Cross-sectional study of the use of antimicrobials following common infections by rural residents in Anhui, China.

Abstract:

OBJECTIVE:To describe help seeking behaviour from a medical doctor and antimicrobial use for common infections among rural residents of Anhui province, China. DESIGN:A cross-sectional retrospective household survey. SETTING:12 administrative villages from rural Anhui, China. PARTICIPANTS:2760 rural residents selected through cluster-randomised sampling using an interviewer administered questionnaire. METHOD:Logistic regression models were used to estimate associations between exposures (health insurance and antimicrobial-related knowledge), adjusted for confounders (sex, age and education), and help-seeking behaviour from a medical doctor and antimicrobial use following common infections, including acute respiratory tract infections (ARTIs), gastrointestinal tract infections (GTIs) and urinary tract infections (UTIs). RESULTS:In total 2611 (94.6%) rural residents completed the questionnaire. Help seeking from a medical doctor was highest for ARTIs (59.4%) followed by GTIs (42.1%), and UTIs (27.8%). Around two-thirds (82.3% for ARTIs, 87.0% for GTIs and 66.0% for UTIs) of respondents sought help within 3 days following symptom onset and over three quarters (88% for ARTIs, 98% for GTIs and 77% for UTIs) reported complete recovery within 7 days. Of the help-seeking respondents, 94.5% with ARTI symptoms recalled being prescribed either oral or intravenous antimicrobials (GTIs 81.7% and UTIs 70.4%). Use of antimicrobials bought from medicine shops without prescriptions ranged from 8.8% for GTIs to 17.2% for ARTIs; while use of antimicrobials leftover from previous illnesses or given by a relative ranged from 7.6% for UTIs to 13.4% for ARTIs. Multivariate logistic regression analysis revealed that respondents with a higher antimicrobial-related knowledge score and lack of insurance were associated with lower levels of help-seeking for ARTIs; while respondents with a higher antimicrobial-related knowledge score were less likely to be prescribed either oral or intravenous antimicrobials. CONCLUSIONS:Excessive antimicrobial use in the studied primary care settings is still prevalent.

journal_name

BMJ Open

journal_title

BMJ open

authors

Chai J,Coope C,Cheng J,Oliver I,Kessel A,Hu Z,Wang D

doi

10.1136/bmjopen-2018-024856

subject

Has Abstract

pub_date

2019-04-11 00:00:00

pages

e024856

issue

4

issn

2044-6055

pii

bmjopen-2018-024856

journal_volume

9

pub_type

杂志文章

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