Unilateral renal artery stenosis presented with hyponatremic-hypertensive syndrome - case report and literature review.

Abstract:

BACKGROUND:Renal artery stenosis is one of the secondary causes of pediatric hypertension. Cases with critical unilateral renal artery stenosis manifesting with the hyponatremic hypertensive syndrome are rare and a comprehensive description of this disorder in the pediatric population is lacking in the literature. CASE PRESENTATION:We describe a 4-year-old boy who presented with severe hypertension, profound hyponatremia, hypokalemia, nephrotic range proteinuria, and polyuria. Distinctly, the diagnosis of hyponatremic hypertensive syndrome secondary to unilateral renal artery stenosis was confirmed in light of laboratory and radiographic findings of severe natriuresis, elevated renin, and unilateral small kidney. Two weeks following nephrectomy, there was resolution of hyponatremia, hypokalemia, nephrotic range proteinuria and hypertension. CONCLUSIONS:Findings of hyponatremia, hypokalemia, hypertension, polyuria, and unilateral renal hypoplasia can be attributed to a unifying pathology of unilateral renal artery stenosis.

journal_name

BMC Nephrol

journal_title

BMC nephrology

authors

Ding JJ,Lin SH,Lai JY,Wu TW,Huang JL,Chung HT,Tseng MH

doi

10.1186/s12882-019-1246-9

subject

Has Abstract

pub_date

2019-02-21 00:00:00

pages

64

issue

1

issn

1471-2369

pii

10.1186/s12882-019-1246-9

journal_volume

20

pub_type

杂志文章