Abstract：
:The ketogenic diet has long been recommended in patients with neurological disorders, and its protective effects on the cardiovascular system are of growing research interest. This study aimed to investigate the effects of two-week of low-calorie ketogenic nutrition drinks in obese adults. Subjects were randomized to consume drinks either a ketone-to-non-ketone ratio of 4:1 (KD 4:1), a drink partially complemented with protein at 1.7:1 (KD 1.7:1), or a balanced nutrition drink (BD). Changes in body weight, body composition, blood lipid profile, and blood ketone bodies were investigated. Blood ketone bodies were induced and maintained in the group that consumed both 4:1 and 1.7:1 ketogenic drinks (p < 0.001). Body weight and body fat mass significantly declined in all groups between 0 and 1 week and between 1 and 2 weeks (p < 0.05), while skeletal muscle mass remained unchanged only in the KD 1.7:1 group (p > 0.05). The blood lipid profile improved, appetite was reduced, and fullness was maintained in the two ketogenic drink groups. This study indicates the possibility for the development of obesity treatments based on ketogenic nutrition drinks even with a moderate ketogenic ratio of 1.7:1, as well as adjuvant therapies based on ketosis induction and maintenance for the treatment of other diseases and health conditions.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Choi HR,Kim J,Lim H,Park YKdoi
10.3390/nu10121895subject
Has Abstractpub_date
2018-12-03 00:00:00issue
12issn
2072-6643pii
nu10121895journal_volume
10pub_type
杂志文章,随机对照试验相关文献
Nutrients文献大全abstract：BACKGROUND:low vitamin D status in pregnancy can influence the offspring's lung function and contribute to childhood asthma development. The objective of this study was to examine the influence of neonatal vitamin D status on the development of asthma among children age 3-9 years in a large population sample. METHOD:i...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12030842
更新日期：2020-03-21 00:00:00
abstract：:High sodium intake is estimated to cause approximately 3 million deaths per year worldwide. The estimated average sodium intake of 3.95 g/day far exceeds the recommended intake. Population sodium reduction should be a global priority, while simultaneously ensuring universal salt iodization. This article identifies hig...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12092543
更新日期：2020-08-22 00:00:00
abstract：:The motivation to seek and consume water is an essential component of human fluid-electrolyte homeostasis, optimal function, and health. This review describes the evolution of concepts regarding thirst and drinking behavior, made possible by magnetic resonance imaging, animal models, and novel laboratory techniques. T...
journal_title：Nutrients
pub_type： 历史文章,杂志文章,评审
doi：10.3390/nu11122864
更新日期：2019-11-22 00:00:00
abstract：:Iron and vitamin D deficiencies are common during pregnancy. Our aim was to identify whether antenatal vitamin D₃ supplementation affects iron status (via hepcidin suppression) and/or inflammation. Using a subset of the UK multicenter Maternal Vitamin D Osteoporosis Study (MAVIDOS)-a double-blinded, randomized, placeb...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu11010190
更新日期：2019-01-18 00:00:00
abstract：:We determined whether ring-2 carbon of histidine is folate-dependently transferred to carbons 8 (C8) and/or 2 (C2) in urinary uric acid in humans. Two adults collected each urine void for four days. Aliquots of urine for the first day were used for baseline values; then the subjects ingested 0.7 g (3.3 mmol) of l-[rin...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu7010697
更新日期：2015-01-20 00:00:00
abstract：:In addition to exhibiting antioxidant properties, conjugated linoleic acid (CLA) and vitamin E may modulate gene expression of endogenous antioxidant enzymes. Depending on cellular microenvironments, such modulation reflects either antioxidant or prooxidant outcomes. Although epidemiological/experimental studies have ...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu2070725
更新日期：2010-07-01 00:00:00
abstract：:People living in non-Mediterranean West Balkan countries have diets with a low n-3 polyunsaturated fatty acid (PUFA) content. Walnuts, a traditional Serbian food, could be an excellent source of n-3 PUFA. The first sub-study evaluated the fatty acid and mineral content of Serbian walnuts, demonstrating that walnuts ha...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu12010192
更新日期：2020-01-10 00:00:00
abstract：:Understanding the regulation of gene activities depending on DNA methylation has been the subject of much recent study. However, although polymorphisms of the HTR2A gene have been associated with both obesity and psychiatric disorders, the role of HTR2A gene methylation in these illnesses remains uncertain. The aim of...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu6062387
更新日期：2014-06-23 00:00:00
abstract：INTRODUCTION:Recent observations have shown that lengthening the daily eating period may contribute to the onset of chronic diseases. Time-restricted eating (TRE) is a diet that especially limits this daily food window. It could represent a dietary approach that is likely to improve health markers. The aim of this stud...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12123770
更新日期：2020-12-08 00:00:00
abstract：:Hyperaminoacidemia following ingestion of cows-milk may stimulate muscle anabolism and attenuate exercise-induced muscle damage (EIMD). However, as dairy-intolerant athletes do not obtain the reported benefits from milk-based products, A2 milk may offer a suitable alternative as it lacks the A1-protein. This study aim...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu9020094
更新日期：2017-01-28 00:00:00
abstract：:High consumption of fructose and high-fructose corn syrup is related to the development of obesity-associated metabolic diseases, which have become the most relevant diet-induced diseases. However, the influences of a high-fructose diet on gut microbiota are still largely unknown. We therefore examined the effect of s...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12113444
更新日期：2020-11-10 00:00:00
abstract：:Gene-environment (G × E) interactions involving job stress and mental health on risk factors of cardiovascular disease (CVD) are minimally explored. This study examined the association and G × E interaction effects of vascular endothelial growth factor receptor-2 (VEGFR-2) gene polymorphisms (rs1870377, rs2071559) on ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051140
更新日期：2019-05-22 00:00:00
abstract：:Consumers' perceptions of five front-of-pack nutrition label formats (health star rating (HSR), multiple traffic lights (MTL), Nutri-Score, reference intakes (RI) and warning label) were assessed across 12 countries (Argentina, Australia, Bulgaria, Canada, Denmark, France, Germany, Mexico, Singapore, Spain, the UK and...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11081934
更新日期：2019-08-16 00:00:00
abstract：:This study investigated the effect of the sodium to potassium ratio on hypertension prevalence and blood pressure. The study population was constructed by pooling the Korean National Health and Nutrition Examination Surveys between 2010 and 2014. The study population was divided into quartiles based on the sodium to p...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8080482
更新日期：2016-08-06 00:00:00
abstract：:A cohort of 50-year-olds from Canterbury, New Zealand (N = 404), representative of midlife adults, undertook comprehensive health and dietary assessments. Fasting plasma vitamin C concentrations (N = 369) and dietary vitamin C intake (N = 250) were determined. The mean plasma vitamin C concentration was 44.2 µmol/L (9...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9080831
更新日期：2017-08-03 00:00:00
abstract：:Omega-3 fatty acids, one of the key building blocks of cell membranes, have been of particular interest to scientists for many years. However, only a small group of the most important omega-3 polyunsaturated fatty acids are considered. This full-length review presents a broad and relatively complete cross-section of k...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu10111662
更新日期：2018-11-04 00:00:00
abstract：:Drug resistance is a major problem in the treatment of non-small-cell lung cancer (NSCLC). In this study, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis was performed to identify the differentially expressed genes in Adriamycin (ADR)-resistant NSCLC A549/ADR cells compared with parental A549 cells. Am...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10121829
更新日期：2018-11-26 00:00:00
abstract：:Whole grain rice is a rich source of fiber, nutrients, and phytochemicals that may promote gastrointestinal health, but such beneficial components are typically removed with the bran during polishing. Soluble feruloylated arabinoxylan oligosaccharides (FAXO) and polyphenols (RBPP) isolated from rice bran are hypothesi...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9111237
更新日期：2017-11-12 00:00:00
abstract：:Glaucoma is a multifactorial blinding disease with a major inflammatory component ultimately leading to apoptotic retinal ganglion cell (RGC) death. Pharmacological treatments lowering intraocular pressure can help slow or prevent vision loss although the damage caused by glaucoma cannot be reversed. Recently, nutriti...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11122931
更新日期：2019-12-03 00:00:00
abstract：:To address limited food frequency questionnaire (FFQ) capacity in public health monitoring in Malaysia, we aimed to develop a semi-quantitative FFQ for an adult multiethnic population for comprehensive fatty acid (FA) profiling inclusive of saturated (SFA), monounsaturated (MUFA), polyunsaturated fatty acids (PUFA), P...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu13010120
更新日期：2020-12-31 00:00:00
abstract：:In the present study, we aimed to investigate whether chronic oral glutamine (Gln) supplementation may alter metabolic parameters and the inflammatory profile in overweight and obese humans as well as whether Gln may modulate molecular pathways in key tissues linked to the insulin action in rats. Thirty-nine overweigh...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu11030536
更新日期：2019-03-01 00:00:00
abstract：:Low diet quality is a driver of general and micronutrient malnutrition in urban and rural areas. The objective was to compare malnutrition and micronutrient deficiencies linked to dietary intake among urban and rural schoolchildren from food insecure settings in Kenya. The cross-sectional study was conducted among urb...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12010207
更新日期：2020-01-13 00:00:00
abstract：:Cocoa has beneficial health effects partly due to its high flavanol content. This study was aimed at assessing the absorption and metabolism of polyphenols in two soluble cocoa products: a conventional (CC) and a flavanol-rich product (CC-PP). A crossover, randomized, blind study was performed in 13 healthy men and wo...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu11071441
更新日期：2019-06-26 00:00:00
abstract：:Sialic acid (SA) is an integral component of gangliosides and signaling molecules in the brain and its dietary intake may support cognitive development. We previously reported that feeding sialyllactose, a milk oligosaccharide that contains SA, alters SA content and diffusivity in the pig brain. The present research s...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10040395
更新日期：2018-03-23 00:00:00
abstract：:Pancreatic β-cells secrete insulin to lower blood glucose, following a meal. Maintenance of β-cell function is essential to preventing type 2 diabetes. In pancreatic β-cells, mitochondrial matrix calcium is an activating signal for insulin secretion. Recently, the molecular identity of the mitochondrial calcium unipor...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12020538
更新日期：2020-02-19 00:00:00
abstract：:(1) Introduction: Current evidence on managing infants under six months with growth failure or other nutrition-related risk is sparse and low quality. This review aims to inform research priorities to fill this evidence gap, focusing on breastfeeding practices. (2) Methods: We searched PubMed, CINAHL Plus, and Cochran...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12072044
更新日期：2020-07-09 00:00:00
abstract：:Milk fat is encased in a polar lipid-containing tri-layer milk fat globule membrane (MFGM), composed of phospholipids (PLs) and sphingolipids (SLs). Milk PLs and SLs comprise about 1% of total milk lipids. The surfactant properties of PLs are important for dairy products; however, dairy products vary considerably in t...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12041001
更新日期：2020-04-04 00:00:00
abstract：:The World Health Organization promotes salt reduction as a best-buy strategy to reduce chronic diseases, and Member States have agreed to a 30% reduction target in mean population salt intake by 2025. Whilst the UK has made the most progress on salt reduction, South Africa was the first country to pass legislation for...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu6093672
更新日期：2014-09-16 00:00:00
abstract：:Large portions of high energy dense (HED) snacks are offered to children from a young age and are pervasive in our food environment. This study aimed to explore the feasibility, acceptability, and preliminary efficacy of two strategies of snack portion control: reduction and replacement. Forty-six mother-child dyads a...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10101493
更新日期：2018-10-12 00:00:00
abstract：:Coffee, wine and chocolate are three frequently consumed substances with a significant impact on cognition. In order to define the structural and cerebral blood flow correlates of self-reported consumption of coffee, wine and chocolate in old age, we assessed cognition and brain MRI measures in 145 community-based eld...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10101391
更新日期：2018-10-01 00:00:00
