Study protocol for a single-centre, prospective, non-blinded, randomised, 12-month, parallel-group superiority study to compare the efficacy of pharmacist intervention versus usual care for elderly patients hospitalised in orthopaedic wards.

abstract：OBJECTIVES:To evaluate the impact of an expansion of liaison psychiatry services (LPS) on patient management, outcomes and treatment costs for emergency department (ED) attendances for self-harm. DESIGN:Retrospective before and after cohort study using routinely collected Self-Harm Surveillance Register data. SETTING...

journal_title：BMJ open

authors： Opmeer BC,Hollingworth W,Marques EMR,Margelyte R,Gunnell D

更新日期：2017-08-21 00:00:00

abstract：OBJECTIVES:To conduct a fully independent, external validation of a research study based on one electronic health record database using a different database sampling from the same population. DESIGN:Retrospective cohort analysis of β-blocker therapy and all-cause mortality in patients with cancer. SETTING:Two UK nati...

journal_title：BMJ open

authors： Springate DA,Ashcroft DM,Kontopantelis E,Doran T,Ryan R,Reeves D

更新日期：2015-04-13 00:00:00

abstract：OBJECTIVE:Neisseria meningitidis carriage prevalence has known variation across the lifespan, but it is unclear whether carriage varies among meningococcal capsular groups. Therefore, we aimed to characterise group-specific meningococcal carriage by age group and world region from 2007 to 2016. DESIGN:Systematic revie...

journal_title：BMJ open

authors： Peterson ME,Li Y,Shanks H,Mile R,Nair H,Kyaw MH,Meningococcal Carriage Group.

更新日期：2019-04-20 00:00:00

abstract：INTRODUCTION:The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery. While this procedure has revolutionised treatment, the incidence of secondary events remains a concern. These repeat events ar...

journal_title：BMJ open

authors： Rathod KS,Jones DA,Van-Eijl TJ,Tsang H,Warren H,Hamshere SM,Kapil V,Jain AK,Deaner A,Poulter N,Caulfield MJ,Mathur A,Ahluwalia A

更新日期：2016-12-20 00:00:00

abstract：OBJECTIVES:Care.data was a 2013 UK government initiative to extract patient data from general practices in England to form a centralised whole-population database for service planning and health research. After a public outcry, the scheme was postponed and cancelled. Public views of care.data have previously been analy...

journal_title：BMJ open

authors： Ford E,Kazempour Y,Cooper MJF,Katikireddi SV,Boyd A

更新日期：2020-09-10 00:00:00

abstract：INTRODUCTION:Trigeminal neuralgia (TN) affects 4 to 28.9/100 000 people worldwide, and antiepileptic drugs such as carbamazepine and oxcarbazepine are the firstline treatment options. However, the efficacy and safety of other antiepileptic drugs remain unclear due to insufficient direct comparisons. OBJECTIVE:To compa...

journal_title：BMJ open

authors： Qin Z,Xie S,Mao Z,Liu Y,Wu J,Furukawa TA,Kwong JSW,Tian J,Liu Z

更新日期：2018-01-21 00:00:00

abstract：OBJECTIVES:To compare the clinical, socioeconomic and demographic characteristics of individuals diagnosed with Neisseria gonorrhoeae (NG) in the community using a concomitant nucleic acid amplification test (NAAT, AptimaCombo2) as part of the (community-based) UK Chlamydia Screening Programme (CSP), with those diagnos...

journal_title：BMJ open

authors： Cook PA,Evans-Jones J,Mallinson H,Wood M,Alloba F,Jones K,Strodtbeck S,Hanna-Bashara L

更新日期：2014-03-14 00:00:00

abstract：INTRODUCTION:Current perspectives present feedback as a dynamic, dialogic process. It is widely accepted that feedback can have an impact on workplace performance, however, how dialogic feedback is enacted with the learner in authentic healthcare settings is less apparent. This paper seeks to describe the design and de...

journal_title：BMJ open

authors： Ossenberg C,Mitchell M,Henderson A

更新日期：2020-06-08 00:00:00

abstract：OBJECTIVE:To describe the circumstances of the elderly with dementia and their caregivers' characteristics in order to examine factors related to activities of daily living (ADL) and household income to propose a long-term care policy for rural areas of Thailand. SETTING:A cross-sectional study at the household level ...

journal_title：BMJ open

authors： Chuakhamfoo NN,Phanthunane P,Chansirikarn S,Pannarunothai S

更新日期：2020-03-24 00:00:00

abstract：OBJECTIVES:To understand the experiences of parents of infants who required surgery early in life. To identify messages and training needs for the extended clinical teams caring for these families-including paediatric surgeons, neonatologists, nurses, obstetricians, midwives and sonographers. SETTING:UK-wide interview...

journal_title：BMJ open

authors： Hinton L,Locock L,Long AM,Knight M

更新日期：2018-06-30 00:00:00

abstract：INTRODUCTION:Osteoarthritis (OA) pain is a major cause of long-term disability and chronic pain in the adult population. One in five patients does not receive satisfactory pain relief, which reflects the complexity of chronic pain and the current lack of understanding of mechanisms of chronic pain. Recently, duloxetine...

journal_title：BMJ open

authors： Reckziegel D,Bailey H,Cottam WJ,Tench CR,Mahajan RP,Walsh DA,Knaggs RD,Auer DP

更新日期：2017-06-26 00:00:00

abstract：INTRODUCTION:Premature infants are particularly vulnerable to brain injuries with associated cognitive and behavioural deficits. The worldwide first randomised interventional multicentre trial investigating the neuroprotective effects of erythropoietin (entitled 'Does erythropoietin improve outcome in very preterm infa...

journal_title：BMJ open

authors： Wehrle FM,Held U,O'Gorman RT,Disselhoff V,Schnider B,Fauchère JC,Hüppi P,Latal B,Hagmann CF

更新日期：2018-04-24 00:00:00

abstract：OBJECTIVE:There has been concern that an increase in billing for high-intensity emergency care is due to changes in coding practices facilitated by electronic health records. We sought to characterise the trends in billing for high-intensity emergency care among Medicare beneficiaries and to examine the degree to which...

journal_title：BMJ open

authors： Burke LG,Wild RC,Orav EJ,Hsia RY

更新日期：2018-01-30 00:00:00

abstract：OBJECTIVE:Osteosarcopenic obesity (OSO) may be associated with an increased prevalence of hypertension. The aim of this study was to examine the difference in the prevalence of OSO and hypertension among four minority populations in China and explore the relationship between OSO and hypertension by sex. DESIGN:This st...

journal_title：BMJ open

authors： Chen X,Kong C,Yu H,Gong J,Lan L,Zhou L,Gong J,Liu P,Xu L,Deng Q

更新日期：2019-07-18 00:00:00

abstract：OBJECTIVES:The need for thorough patient information is increasing as maternity care becomes more medicalised. The aim was to assess the quality of written patient information on labour induction. In most Danish hospitals, misoprostol is the first-choice drug for induction in low-risk pregnancies. Misoprostol has been ...

journal_title：BMJ open

authors： Clausen JA,Juhl M,Rydahl E

更新日期：2016-05-27 00:00:00

abstract：OBJECTIVES:In England, the NHS111 service provides assessment and triage by telephone for urgent health problems. A digital version of this service has recently been introduced. We aimed to systematically review the evidence on digital and online symptom checkers and similar services. DESIGN:Systematic review. DATA S...

journal_title：BMJ open

authors： Chambers D,Cantrell AJ,Johnson M,Preston L,Baxter SK,Booth A,Turner J

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:To clarify the association between glucose intolerance and high altitudes (2900-4800 m) in a hypoxic environment in Tibetan highlanders and to verify the hypothesis that high altitude dwelling increases vulnerability to diabetes mellitus (DM) accelerated by lifestyle change or ageing. DESIGN:Cross-sectional...

journal_title：BMJ open

authors： Okumiya K,Sakamoto R,Ishimoto Y,Kimura Y,Fukutomi E,Ishikawa M,Suwa K,Imai H,Chen W,Kato E,Nakatsuka M,Kasahara Y,Fujisawa M,Wada T,Wang H,Dai Q,Xu H,Qiao H,Ge RL,Norboo T,Tsering N,Kosaka Y,Nose M,Yamaguchi

更新日期：2016-02-23 00:00:00

abstract：OBJECTIVE:Since most biomedical research focuses on a specific disease, evaluation of research output requires disease-specific bibliometric indicators. Currently used methods are insufficient. The aim of this study is to develop a method that enables detailed analysis of worldwide biomedical research output by disease...

journal_title：BMJ open

authors： van de Laar L,de Kruif T,Waltman L,Meijer I,Gupta A,Hagenaars N

更新日期：2018-06-04 00:00:00

abstract：OBJECTIVE:The risk of fetal death increases steeply after 42 gestational weeks. Since 2009, Denmark has had a more proactive policy including prevention of prolonged pregnancy, and early intervention in women with diabetes, preeclampsia, high body mass index and of a higher age group. The aim of this study was to descr...

journal_title：BMJ open

authors： Hedegaard M,Lidegaard Ø,Skovlund CW,Mørch LS,Hedegaard M

更新日期：2014-08-14 00:00:00

abstract：OBJECTIVE:To explore the perspectives of primary healthcare (PHC) professionals providing care to refugees through mainstream general practice. DESIGN:Qualitative exploratory design with semistructured interviews subjected to inductive thematic analysis. SETTING AND PARTICIPANTS:Nine general practices enrolled in the...

journal_title：BMJ open

authors： Richard L,Richardson G,Jaye C,Stokes T

更新日期：2019-12-31 00:00:00

abstract：OBJECTIVES:Despite widespread availability of evidence-based guidelines to inform rational use of medicines, considerable unwarranted variation exists in prescribing. A greater understanding of key determinants of contemporary prescribing in UK general practice could inform strategies to promote evidence-based prescrib...

journal_title：BMJ open

authors： Carter M,Chapman S,Watson MC

更新日期：2021-01-11 00:00:00

abstract：OBJECTIVES:This study aims to examine the tracking and predictability of physical activity in old age from overall physical activity and participation in sport, recreational activity and walking in mid-life. DESIGN:Prospective population-based cohort study. SETTING:British Regional Heart Study participants recruited ...

journal_title：BMJ open

authors： Aggio D,Papacosta O,Lennon L,Whincup P,Wannamethee G,Jefferis BJ

更新日期：2017-09-21 00:00:00

abstract：INTRODUCTION:Recreational drug use in the nightlife setting carries the risk of many negative consequences, such as violence, injuries, aberrant driving and sexual risk-taking. The aim of this study is to investigate recreational drug use and user characteristics among people visiting licensed premises, for example, ni...

journal_title：BMJ open

authors： Nordfjærn T,Edland-Gryt M,Bretteville-Jensen AL,Buvik K,Gripenberg J

更新日期：2016-04-22 00:00:00

abstract：OBJECTIVES:We aimed to examine longitudinally whether workplace bullying was associated with subsequent psychotropic medication among women and men. DESIGN:A cohort study. SETTING:Helsinki, Finland. PARTICIPANTS:Employees of the City of Helsinki, Finland (n=6606, 80% women), 40-60 years at baseline in 2000-2002, and...

journal_title：BMJ open

authors： Lallukka T,Haukka J,Partonen T,Rahkonen O,Lahelma E

更新日期：2012-12-12 00:00:00

abstract：INTRODUCTION:Developmental alterations to the circadian rhythm, in combination with lifestyle changes (eg, changes in school start time, part-time employment), contribute to insufficient sleep among youth. Insufficient sleep is associated with poor eating behaviours in other developmental stages (ie, childhood, adultho...

journal_title：BMJ open

authors： Doan N,Ferro MA

更新日期：2019-12-11 00:00:00

abstract：INTRODUCTION:WHO recommends the introduction of at least one single dose of inactivated polio vaccine (IPV) in routine immunisation schedules. Thus, there has been an increased demand and concurrent supply shortages of IPV worldwide. One of the strategies to improve access is the use of fractional instead of full doses...

journal_title：BMJ open

authors： Mashunye TR,Ndwandwe DE,Dube KR,Shey M,Shelton M,Wiysonge CS

更新日期：2019-03-09 00:00:00

abstract：OBJECTIVES:Mental health problems and hazardous alcohol consumption often co-exist. Hazardous drinking could have a negative impact on different aspects of health and also negatively influence the effect of mental health treatment. The aims of this study were to examine if alcohol consumption patterns changed after tre...

journal_title：BMJ open

authors： Strid C,Hallgren M,Forsell Y,Kraepelien M,Öjehagen A

更新日期：2019-11-10 00:00:00

abstract：INTRODUCTION:The improvement in breast cancer survival rates, along with the expected overdiagnosis and overtreatment associated with breast cancer screening, requires a comprehensive assessment of its burden. Neurological complications can have a devastating impact on these patients; neuropathic pain and chemotherapy-...

journal_title：BMJ open

authors： Pereira S,Fontes F,Sonin T,Dias T,Fragoso M,Castro-Lopes J,Lunet N

更新日期：2014-10-28 00:00:00

abstract：OBJECTIVE:Evidence-based performance measures have been increasingly used to evaluate hospital quality of stroke care, but their impact on stroke outcomes has not been verified. We aimed to evaluate the correlations between hospital performance measures and outcomes among patients with acute ischaemic stroke in a Chine...

journal_title：BMJ open

authors： Zhang X,Li Z,Zhao X,Xian Y,Liu L,Wang C,Wang C,Li H,Prvu Bettger J,Yang Q,Wang D,Jiang Y,Bao X,Yang X,Wang Y,Wang Y

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To examine the damage location distribution of five main body region injuries of maximum abbreviated injury score (MAIS) 3-6 injured occupants for nearside struck vehicle in front-to-side impact crashes. DESIGN AND SETTING:MAIS 3-6 injured occupants information was extracted from the US-National Automotive ...

journal_title：BMJ open

authors： Tang Y,Cao L,Kan S

更新日期：2014-05-08 00:00:00