Evaluating patterns and predictors of symptom change during a three-week intensive outpatient treatment for veterans with PTSD.

Abstract:

BACKGROUND:Intensive delivery of evidence-based treatment for posttraumatic stress disorder (PTSD) is becoming increasingly popular for overcoming barriers to treatment for veterans. Understanding how and for whom these intensive treatments work is critical for optimizing their dissemination. The goals of the current study were to evaluate patterns of PTSD and depression symptom change over the course of a 3-week cohort-based intensive outpatient program (IOP) for veterans with PTSD, examine changes in posttraumatic cognitions as a predictor of treatment response, and determine whether patterns of treatment outcome or predictors of treatment outcome differed by sex and cohort type (combat versus military sexual trauma [MST]). METHOD:One-hundred ninety-one veterans (19 cohorts: 12 combat-PTSD cohorts, 7 MST-PTSD cohorts) completed a 3-week intensive outpatient program for PTSD comprised of daily group and individual Cognitive Processing Therapy (CPT), mindfulness, yoga, and psychoeducation. Measures of PTSD symptoms, depression symptoms, and posttraumatic cognitions were collected before the intervention, after the intervention, and approximately every other day during the intervention. RESULTS:Pre-post analyses for completers (N = 176; 92.1% of sample) revealed large reductions in PTSD (d = 1.12 for past month symptoms and d = 1.40 for past week symptoms) and depression symptoms (d = 1.04 for past 2 weeks). Combat cohorts saw a greater reduction in PTSD symptoms over time relative to MST cohorts. Reduction in posttraumatic cognitions over time significantly predicted decreases in PTSD and depression symptom scores, which remained robust to adjustment for autocorrelation. CONCLUSION:Intensive treatment programs are a promising approach for delivering evidence-based interventions to produce rapid treatment response and high rates of retention. Reductions in posttraumatic cognitions appear to be an important predictor of response to intensive treatment. Further research is needed to explore differences in intensive treatment response for veterans with combat exposure versus MST.

journal_name

BMC Psychiatry

journal_title

BMC psychiatry

authors

Zalta AK,Held P,Smith DL,Klassen BJ,Lofgreen AM,Normand PS,Brennan MB,Rydberg TS,Boley RA,Pollack MH,Karnik NS

doi

10.1186/s12888-018-1816-6

subject

Has Abstract

pub_date

2018-07-27 00:00:00

pages

242

issue

1

issn

1471-244X

pii

10.1186/s12888-018-1816-6

journal_volume

18

pub_type

杂志文章
  • The prevalence of psychiatric disorders among students aged 6~ 16 years old in central Hunan, China.

    abstract:BACKGROUND:Though several epidemiological surveys of psychiatric disorders have been carried out in China, only a few of them are concerned about the prevalence of psychiatric disorders in central Hunan and reveal the distribution of common psychiatric disorders and their comorbidities. METHODS:Achenbach's Child Behav...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-018-1823-7

    authors: Shen YM,Chan BSM,Liu JB,Zhou YY,Cui XL,He YQ,Fang YM,Xiang YT,Luo XR

    更新日期:2018-07-28 00:00:00

  • Treatment utilization and treatment barriers in individuals with body dysmorphic disorder.

    abstract:BACKGROUND:Although effective treatments are available, most individuals with body dysmorphic disorder (BDD) do not receive an appropriate diagnosis or treatment. We aimed to examine treatment utilization and barriers to treatment, and to identify associated socio-demographic and clinical characteristics. METHODS:Germ...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-020-02489-0

    authors: Schulte J,Schulz C,Wilhelm S,Buhlmann U

    更新日期:2020-02-18 00:00:00

  • Suicidal ideation among the hypertensive individuals in Shandong, China: a path analysis.

    abstract:BACKGROUND:Although massive studies have explored the risk factors of suicidal ideation (SI), the prevalence of SI and its associated factors in the hypertensive individuals are largely unknown. This study aims to investigate the factors associated with SI in the hypertensive individuals. METHODS:Three thousand nine h...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-019-2256-7

    authors: Ge D,Zhang X,Guo X,Chu J,Sun L,Zhou C

    更新日期:2019-09-02 00:00:00

  • A clinical approach to the assessment and management of co-morbid eating disorders and substance use disorders.

    abstract:INTRODUCTION:Research has shown that eating disorder (ED) patients who abuse substances demonstrate worse ED symptomatology and poorer outcomes than those with EDs alone, including increased general medical complications and psychopathology, longer recovery times, poorer functional outcomes and higher relapse rates. Th...

    journal_title:BMC psychiatry

    pub_type: 杂志文章,评审

    doi:10.1186/1471-244X-13-289

    authors: Gregorowski C,Seedat S,Jordaan GP

    更新日期:2013-11-07 00:00:00

  • The Bipolar Affective Disorder Dimension Scale (BADDS)--a dimensional scale for rating lifetime psychopathology in bipolar spectrum disorders.

    abstract:BACKGROUND:Current operational diagnostic systems have substantial limitations for lifetime diagnostic classification of bipolar spectrum disorders. Issues include: (1) It is difficult to operationalize the integration of diverse episodes of psychopathology, (2) Hierarchies lead to loss of information, (3) Boundaries b...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/1471-244X-4-19

    authors: Craddock N,Jones I,Kirov G,Jones L

    更新日期:2004-07-05 00:00:00

  • Cognitive change is more positively associated with an active lifestyle than with training interventions in older adults at risk of dementia: a controlled interventional clinical trial.

    abstract:BACKGROUND:While observational studies show that an active lifestyle including cognitive, physical, and social activities is associated with a reduced risk of cognitive decline and dementia, experimental evidence from corresponding training interventions is more inconsistent with less pronounced effects. The aim of thi...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-016-1018-z

    authors: Küster OC,Fissler P,Laptinskaya D,Thurm F,Scharpf A,Woll A,Kolassa S,Kramer AF,Elbert T,von Arnim CA,Kolassa IT

    更新日期:2016-09-08 00:00:00

  • Community outreach for patients who have difficulties in maintaining contact with mental health services: longitudinal retrospective study of the Japanese outreach model project.

    abstract:BACKGROUND:Japan still has the highest ratio of beds devoted to psychiatric patients in the world. In 2011, in order to reduce re-hospitalization of patients who became disconnected from regular contact with outpatient medical services, the Japanese Ministry established the Japanese Outreach Model Project (JOMP). In th...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-014-0311-y

    authors: Kayama M,Kido Y,Setoya N,Tsunoda A,Matsunaga A,Kikkawa T,Fukuda T,Noguchi M,Mishina K,Nishio M,Ito J

    更新日期:2014-11-18 00:00:00

  • Correction to: Dialectical behaviour therapy for treating adults and adolescents with emotional and behavioural dysregulation: study protocol of a coordinated implementation in a publicly funded health service.

    abstract::Upon publication of the original article (1) it was highlighted by the authors that there was just one error in the manuscript in the 'Sample size' subsection of the Methods/Design. ...

    journal_title:BMC psychiatry

    pub_type: 杂志文章,已发布勘误

    doi:10.1186/s12888-018-1694-y

    authors: Flynn D,Kells M,Joyce M,Suarez C,Gillespie C

    更新日期:2018-05-07 00:00:00

  • Poly-substance use and antisocial personality traits at admission predict cumulative retention in a buprenorphine programme with mandatory work and high compliance profile.

    abstract:BACKGROUND:Continuous abstinence and retention in treatment for alcohol and drug use disorders are central challenges for the treatment providers. The literature has failed to show consistent, strong predictors of retention. Predictors and treatment structure may differ across treatment modalities. In this study the st...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/1471-244X-11-81

    authors: Öhlin L,Hesse M,Fridell M,Tätting P

    更新日期:2011-05-12 00:00:00

  • Potential diagnostic markers of olanzapine efficiency for acute psychosis: a focus on peripheral biogenic amines.

    abstract:BACKGROUND:Biomarkers are now widely used in many fields of medicine, and the identification of biomarkers that predict antipsychotic efficacy and adverse reactions is a growing area of psychiatric research. Monoamine molecules of the peripheral bloodstream are possible prospective biomarkers based on a growing body of...

    journal_title:BMC psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12888-017-1562-1

    authors: Taraskina AE,Nasyrova RF,Zabotina AM,Sosin DN,Sosina КА,Ershov EE,Grunina MN,Krupitsky EM

    更新日期:2017-12-08 00:00:00

  • Ego defense mechanisms in Pakistani medical students: a cross sectional analysis.

    abstract:BACKGROUND:Ego defense mechanisms (or factors), defined by Freud as unconscious resources used by the ego to reduce conflict between the id and superego, are a reflection of how an individual deals with conflict and stress. This study assesses the prevalence of various ego defense mechanisms employed by medical student...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/1471-244X-10-12

    authors: Parekh MA,Majeed H,Khan TR,Khan AB,Khalid S,Khwaja NM,Khalid R,Khan MA,Rizqui IM,Jehan I

    更新日期:2010-01-29 00:00:00

  • Analysis on evolution and research focus in psychiatry field.

    abstract:BACKGROUND:With the dramatic rise in mental disorders and mental illnesses, psychiatry has become one of the fastest growing clinical medical disciplines. This has led to a rise in the number of scientific research papers being published in this field. METHODS:We selected research papers in ten psychiatric journals th...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-015-0482-1

    authors: Wu Y,Duan Z

    更新日期:2015-05-07 00:00:00

  • High vitamin B12 level and good treatment outcome may be associated in major depressive disorder.

    abstract:BACKGROUND:Despite of an increasing body of research the associations between vitamin B12 and folate levels and the treatment outcome in depressive disorders are still unsolved. We therefore conducted this naturalistic prospective follow-up study. Our aim was to determine whether there were any associations between the...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/1471-244X-3-17

    authors: Hintikka J,Tolmunen T,Tanskanen A,Viinamäki H

    更新日期:2003-12-02 00:00:00

  • Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): new pharmacological treatment options for crack-cocaine dependence in the Netherlands.

    abstract:BACKGROUND:Cocaine, particularly in its base form ('crack'), has become one of the drugs of most concern in the Netherlands, being associated with a wide range of medical, psychiatric and social problems for the individual, and with significant public order consequences for society. Available treatment options for coca...

    journal_title:BMC psychiatry

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1471-244X-11-135

    authors: Nuijten M,Blanken P,van den Brink W,Hendriks V

    更新日期:2011-08-19 00:00:00

  • Psychometric properties of the self-report version of the Quick Inventory of Depressive Symptoms (QIDS-SR₁₆) questionnaire in patients with schizophrenia.

    abstract:BACKGROUND:Self-report instruments for the assessment of depressive symptoms in patients with psychotic disorders are scarce. The Quick Inventory of Depressive Symptoms (QIDS-SR16) may be a useful self-report instrument, but has received little attention in this field. This paper aimed to test the psychometric properti...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-014-0247-2

    authors: Lako IM,Wigman JT,Klaassen RM,Slooff CJ,Taxis K,Bartels-Velthuis AA,GROUP investigators.

    更新日期:2014-09-03 00:00:00

  • The establishment of the objective diagnostic markers and personalized medical intervention in patients with major depressive disorder: rationale and protocol.

    abstract:BACKGROUND:Major depressive disorders (MDD) is a common mental disorder with high prevalence, frequent relapse and associated with heavy disease burden. Heritability, environment and their interaction play important roles in the development of MDD. MDD patients usually display a wide variation in clinical symptoms and ...

    journal_title:BMC psychiatry

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1186/s12888-016-0953-z

    authors: Lv X,Si T,Wang G,Wang H,Liu Q,Hu C,Wang J,Su Y,Huang Y,Jiang H,Yu X

    更新日期:2016-07-15 00:00:00

  • The impact of immigration detention on mental health: a systematic review.

    abstract:BACKGROUND:The number of asylum seekers, refugees and internally displaced people worldwide has increased dramatically over the past 5 years. Many countries are continuing to resort to detaining asylum seekers and other migrants, despite concerns that this may be harmful. In light of the considerable body of recent res...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-018-1945-y

    authors: von Werthern M,Robjant K,Chui Z,Schon R,Ottisova L,Mason C,Katona C

    更新日期:2018-12-06 00:00:00

  • Borderline personality disorder and violence in the UK population: categorical and dimensional trait assessment.

    abstract:BACKGROUND:Borderline personality disorder (BPD) is characterised by difficulties with impulse control and affective dysregulation. It is unclear whether BPD contributes to the perpetration of violence or whether this is explained by comorbidity. We explored independent associations between categorical and dimensional ...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-016-0885-7

    authors: González RA,Igoumenou A,Kallis C,Coid JW

    更新日期:2016-06-03 00:00:00

  • A cross-sectional study on spouse and parent differences in caregiving experiences of people living with schizophrenia in rural China.

    abstract:BACKGROUND:Conflicting evidence exists on whether parent or spouse caregivers experience better outcomes when caring for family members with schizophrenia. The current study aims to examine relative caregiving experiences and impacts of spouse and parent caregivers for people living with schizophrenia (PLS) in China. ...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-020-02633-w

    authors: Yu Y,Li TX,Li YL,Qiu D,Xi SJ,Xiao SY,Tebes JK

    更新日期:2020-05-12 00:00:00

  • Understanding and meeting information needs for patients with posttraumatic stress disorder.

    abstract:BACKGROUND:Posttraumatic Stress Disorder (PTSD) is a commonly occurring mental illness. There are multiple treatments for PTSD that have similar effectiveness, but these treatments differ substantially in other ways. It is desirable to have well-informed patients involved in treatment choices. A patient decision aid (P...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-016-0724-x

    authors: Watts BV,Zayed MH,Llewellyn-Thomas H,Schnurr PP

    更新日期:2016-02-01 00:00:00

  • Adolescent self-harm in Ghana: a qualitative interview-based study of first-hand accounts.

    abstract:BACKGROUND:Recent prevalence studies suggest that self-harm among adolescents in sub-Saharan Africa is as common as it is in high income countries. However, very few qualitative studies exploring first-person accounts of adolescent self-harm are available from sub-Saharan Africa. We sought to explore the experiences an...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-020-02599-9

    authors: Quarshie EN,Waterman MG,House AO

    更新日期:2020-06-01 00:00:00

  • High-dose benzodiazepine dependence: a qualitative study of patients' perception on cessation and withdrawal.

    abstract:BACKGROUND:Benzodiazepine withdrawal syndrome has been reported following attempts to withdraw even from low or therapeutic doses and has been compared to barbiturate and alcohol withdrawal. This experience is known to deter patients from future cessation attempts. Research on other psychotropic substances shows that t...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-015-0493-y

    authors: Liebrenz M,Gehring MT,Buadze A,Caflisch C

    更新日期:2015-05-13 00:00:00

  • Evaluating differential developmental trajectories to adolescent-onset mood and psychotic disorders.

    abstract:BACKGROUND:It is an open question as to whether differential developmental trajectories, potentially representing underlying pathophysiological processes, can form the basis of a more useful typology in young persons who present for mental health care. METHODS:A cohort of 605 young people was recruited from youth ment...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/1471-244X-13-303

    authors: Hickie IB,Hermens DF,Naismith SL,Guastella AJ,Glozier N,Scott J,Scott EM

    更新日期:2013-11-12 00:00:00

  • Onset of common mental disorders and suicidal behavior following women's first exposure to gender based violence: a retrospective, population-based study.

    abstract:BACKGROUND:Women exposed to gender-based violence (GBV) experience a high rate of common mental disorders and suicidal behaviour ("mental disturbance"). Little is known however about the timing of onset of mental disturbance following first exposure to GBV amongst women with no prior mental disorder. METHODS:The analy...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-014-0312-x

    authors: Rees S,Steel Z,Creamer M,Teesson M,Bryant R,McFarlane AC,Mills KL,Slade T,Carragher N,O'Donnell M,Forbes D,Silove D

    更新日期:2014-11-18 00:00:00

  • Harsh discipline relates to internalizing problems and cognitive functioning: findings from a cross-sectional study with school children in Tanzania.

    abstract:BACKGROUND:Child maltreatment poses a risk to children and adolescents' mental health and may also affect cognitive functioning. Also harsh discipline has been frequently associated with mental health problems. However, within societies in which harsh disciplinary methods are culturally normed and highly prevalent less...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-016-0828-3

    authors: Hecker T,Hermenau K,Salmen C,Teicher M,Elbert T

    更新日期:2016-04-29 00:00:00

  • Relevance of a subjective quality of life questionnaire for long-term homeless persons with schizophrenia.

    abstract:BACKGROUND:Increasing numbers of programs are addressing the specific needs of homeless people with schizophrenia in terms of access to housing, healthcare, basic human rights and other domains. Although quality of life scales are being used to evaluate such programs, few instruments have been validated for people with...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-017-1227-0

    authors: Girard V,Tinland A,Bonin JP,Olive F,Poule J,Lancon C,Apostolidis T,Rowe M,Greacen T,Simeoni MC

    更新日期:2017-02-17 00:00:00

  • Mental health of refugees following state-sponsored repatriation from Germany.

    abstract:BACKGROUND:In recent years, Voluntary Assisted Return Programmes (VARPs) have received increasing funding as a potential way of reducing the number of refugees in EU member states. A number of factors may affect the mental well-being of returnees. These include adjustment to the home country following return, difficult...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/1471-244X-8-88

    authors: von Lersner U,Elbert T,Neuner F

    更新日期:2008-11-10 00:00:00

  • Stress reactions after a patient suicide and their relations to the profile of mental health professionals.

    abstract:BACKGROUND:Patient suicide is a professional hazard for mental health professionals and an event likely to trigger stress reactions among them. This study aimed to identify typical profiles of professionals after a patient suicide to address the severity of stress reactions and its discriminant variables. METHODS:Ment...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-015-0655-y

    authors: Castelli Dransart DA,Heeb JL,Gulfi A,Gutjahr EM

    更新日期:2015-10-28 00:00:00

  • Developmental brain trajectories in children with ADHD and controls: a longitudinal neuroimaging study.

    abstract:BACKGROUND:The symptom profile and neuropsychological functioning of individuals with Attention Deficit/Hyperactivity Disorder (ADHD), change as they enter adolescence. It is unclear whether variation in brain structure and function parallels these changes, and also whether deviations from typical brain development tra...

    journal_title:BMC psychiatry

    pub_type: 杂志文章

    doi:10.1186/s12888-016-0770-4

    authors: Silk TJ,Genc S,Anderson V,Efron D,Hazell P,Nicholson JM,Kean M,Malpas CB,Sciberras E

    更新日期:2016-03-11 00:00:00

  • Training in dual diagnosis interventions (the COMO Study): randomised controlled trial.

    abstract:BACKGROUND:Despite the high prevalence of co-morbid substance use among mental health service users (dual diagnosis), very few mental health workers in the UK have had training and/or clinical experience to equip them to deliver targeted interventions to this client group. METHOD:In a randomised controlled trial of tr...

    journal_title:BMC psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-244X-8-12

    authors: Hughes E,Wanigaratne S,Gournay K,Johnson S,Thornicroft G,Finch E,Marshall J,Smith N

    更新日期:2008-02-27 00:00:00