Correction to: Metalloproteases meprin-ɑ (MEP1A) is a prognostic biomarker and promotes proliferation and invasion of colorectal cancer.

abstract：BACKGROUND:The relationship between non-steroidal anti-inflammatory drug (NSAID) consumption and breast cancer has been repeatedly studied, although the results remain controversial. Most case-control studies reported that NSAID consumption protected against breast cancer, while most cohort studies did not find this ef...

journal_title：BMC cancer

authors： Dierssen-Sotos T,Gómez-Acebo I,de Pedro M,Pérez-Gómez B,Servitja S,Moreno V,Amiano P,Fernandez-Villa T,Barricarte A,Tardon A,Diaz-Santos M,Peiro-Perez R,Marcos-Gragera R,Lope V,Gracia-Lavedan E,Alonso MH,Michelena-Echeves

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:Fast-track colonoscopy to detect patients with colorectal cancer based on high-risk symptoms is associated with low sensitivity and specificity. The aim was to derive a predictive score of advanced colonic neoplasia in symptomatic patients in fast-track programs. METHODS:All patients referred for fast-track...

journal_title：BMC cancer

authors： Fernández-Bañares F,Clèries R,Boadas J,Ribes J,Oliva JC,Alsius A,Sanz X,Martínez-Bauer E,Galter S,Pujals M,Pujol M,Del Pozo P,Campo R

更新日期：2019-07-25 00:00:00

abstract：BACKGROUND:Estrogen (17β-estradiol) promotes the survival and proliferation of breast cancer cells and its receptors represent important therapeutic targets. The cellular actions of estrogen are mediated by the nuclear estrogen receptors ERα and ERβ as well as the 7-transmembrane spanning G protein-coupled estrogen rec...

journal_title：BMC cancer

authors： Zekas E,Prossnitz ER

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:Pembrolizumab is effective as first-line therapy against advanced non-small cell lung cancer (NSCLC) in patients with programmed death ligand-1 (PD-L1) expression levels ≥50% [1]. However, it is not effective in all patients, and the factors predicting responses among this population remain unknown. METHODS...

journal_title：BMC cancer

authors： Morita M,Tamiya M,Fujimoto D,Tamiya A,Suzuki H,Hirano K,Fukuda Y,Yokoyama T,Kominami R,Kanazu M,Uchida J,Hara S,Yamashita S,Tomioka H

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Although radical surgery remains the cornerstone of cure in resectable gastric cancer, survival remains poor. Current evidence-based (neo)adjuvant strategies have shown to improve outcome, including perioperative chemotherapy, postoperative chemoradiotherapy and postoperative chemotherapy. However, these reg...

journal_title：BMC cancer

authors： Slagter AE,Jansen EPM,van Laarhoven HWM,van Sandick JW,van Grieken NCT,Sikorska K,Cats A,Muller-Timmermans P,Hulshof MCCM,Boot H,Los M,Beerepoot LV,Peters FPJ,Hospers GAP,van Etten B,Hartgrink HH,van Berge Henegouwen MI,

更新日期：2018-09-10 00:00:00

abstract：BACKGROUND:CD73 has both enzymatic and non-enzymatic functions in cells. As a nucleotidase, CD73 plays its enzymatic function by catalyzing the hydrolysis of AMP into adenosine and phosphate. In addition to this, accumulating data have shown that CD73 is a key regulatory molecule involved in cancer growth and metastasi...

journal_title：BMC cancer

authors： Gao ZW,Wang HP,Lin F,Wang X,Long M,Zhang HZ,Dong K

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the impact of the Controlling Nutritional Status (CONUT) score on survival compared with the platelet to lymphocyte ratio (PLR), the neutrophil to lymphocyte ratio (NLR), and the Glasgow Prognostic Score (GPS) in patients with resectable thoracic esophageal squamo...

journal_title：BMC cancer

authors： Toyokawa T,Kubo N,Tamura T,Sakurai K,Amano R,Tanaka H,Muguruma K,Yashiro M,Hirakawa K,Ohira M

更新日期：2016-09-06 00:00:00

abstract：BACKGROUND:Survival after diagnosis is a fundamental concern in cancer epidemiology. In resource-rich settings, ambient clinical databases, municipal data and cancer registries make survival estimation in real-world populations relatively straightforward. In resource-poor settings, given the deficiencies in a variety o...

journal_title：BMC cancer

authors： Freeman E,Semeere A,Wenger M,Bwana M,Asirwa FC,Busakhala N,Oga E,Jedy-Agba E,Kwaghe V,Iregbu K,Jaquet A,Dabis F,Yumo HA,Dusingize JC,Bangsberg D,Anastos K,Phiri S,Bohlius J,Egger M,Yiannoutsos C,Wools-Kaloustian K

更新日期：2016-02-06 00:00:00

abstract：:After publication of the original article [1] the authors found that the article contained an incorrect version of Fig. 4. This does not affect the results and conclusions of the article. ...

journal_title：BMC cancer

authors： Kaveh F,Baumbusch LO,Nebdal D,Børresen-Dale AL,Lingjærde OC,Edvardsen H,Kristensen VN,Solvang HK

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:The use of high-dose chemotherapy combined with autologous stem cell transplantation has improved the outcome of hematologic malignancies. Nevertheless, this treatment can cause persistent fatigue and a reduced global quality of life, role and physical function. Physical exercise interventions may be benefic...

journal_title：BMC cancer

authors： Persoon S,Kersten MJ,Chinapaw MJ,Buffart LM,Burghout H,Schep G,Brug J,Nollet F

更新日期：2010-12-06 00:00:00

abstract：BACKGROUND:From 2008, Danish general practitioners could refer patients suspected of having cancer to standardised cancer patient pathways (CPPs). We aimed to compare the length of the diagnostic interval in 2010 with the length of the diagnostic interval before (2004/05) and during (2007/08) the implementation of CPPs...

journal_title：BMC cancer

authors： Jensen H,Tørring ML,Olesen F,Overgaard J,Fenger-Grøn M,Vedsted P

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Although advanced-stage cervical cancer can benefit from current treatments, approximately 30% patients may fail after definitive treatment eventually. Therefore, exploring alternative molecular therapeutic approaches is imperatively needed for this disease. We have recently shown that activation of AMP-acti...

journal_title：BMC cancer

authors： Yung MM,Chan DW,Liu VW,Yao KM,Ngan HY

更新日期：2013-07-03 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are short, non-coding RNAs (~22 nt) that play important roles in the pathogenesis of human diseases by negatively regulating gene expression. Although miR-196a has been implicated in several other cancers, its role in non-small cell lung cancer (NSCLC) is unknown. The aim of the present st...

journal_title：BMC cancer

authors： Liu XH,Lu KH,Wang KM,Sun M,Zhang EB,Yang JS,Yin DD,Liu ZL,Zhou J,Liu ZJ,De W,Wang ZX

更新日期：2012-08-09 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors are the first line standard of care for treatment of metastatic renal cell carcinoma (RCC). Accurate response assessment in the setting of antiangiogenic therapies remains suboptimal as standard size-related response criteria do not necessarily accurately reflect clinical benefit, ...

journal_title：BMC cancer

authors： Kelly-Morland C,Rudman S,Nathan P,Mallett S,Montana G,Cook G,Goh V

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:The effectiveness of cervical cancer screening programs is challenged by suboptimal participation and coverage. Offering cervico-vaginal self-sampling for human papillomavirus testing (HPV self-sampling) to non-participants can increase screening participation. However, the effect varies substantially among ...

journal_title：BMC cancer

authors： Tranberg M,Bech BH,Blaakær J,Jensen JS,Svanholm H,Andersen B

更新日期：2016-11-03 00:00:00

abstract：BACKGROUND:Earlier studies have reported the production of histamine in colorectal cancers (CRCs). The effect of histamine is largely determined locally by the histamine receptor expression pattern. Recent evidence suggests that the expression level of histamine receptor H4 (HRH4) is abnormal in colorectal cancer tissu...

journal_title：BMC cancer

authors： Fang Z,Yao W,Xiong Y,Li J,Liu L,Shi L,Zhang W,Zhang C,Nie L,Wan J

更新日期：2011-05-24 00:00:00

abstract：BACKGROUND:The goal of this exploratory study was to develop and assess a prediction model which can potentially be used as a biomarker of breast cancer, based on anthropometric data and parameters which can be gathered in routine blood analysis. METHODS:For each of the 166 participants several clinical features were ...

journal_title：BMC cancer

authors： Patrício M,Pereira J,Crisóstomo J,Matafome P,Gomes M,Seiça R,Caramelo F

更新日期：2018-01-04 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NAC) is one of the standard care regimens for patients with resectable early-stage breast cancer. It would be advantageous to determine the chemosensitivity of tumors before initiating NAC. One of the parameters potentially compromising such chemosensitivity would be a hypoxic micro...

journal_title：BMC cancer

authors： Aomatsu N,Yashiro M,Kashiwagi S,Kawajiri H,Takashima T,Ohsawa M,Wakasa K,Hirakawa K

更新日期：2014-06-04 00:00:00

abstract：BACKGROUND:Higher sunlight exposure is correlated with lower incidence of breast cancer in ecological studies, but findings from prospective studies regarding the association of circulating levels of vitamin D with the risk of breast cancer have been null. The objective of this study was to examine the relation between...

journal_title：BMC cancer

authors： Kim Y,Franke AA,Shvetsov YB,Wilkens LR,Cooney RV,Lurie G,Maskarinec G,Hernandez BY,Le Marchand L,Henderson BE,Kolonel LN,Goodman MT

更新日期：2014-01-17 00:00:00

abstract：BACKGROUND:Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is accepted standard for prevention of chemotherapy-induced neutropenia. RGB-02 (Gedeon Richter) is a proposed biosimilar to pegylated G-CSF (Neulasta®, Amgen) with sustained release properties. This is a randomized, comparative, ...

journal_title：BMC cancer

authors： Kahan Z,Grecea D,Smakal M,Tjulandin S,Bondarenko I,Perjesi L,Illes A,Horvat-Karajz K,Aradi I

更新日期：2019-02-06 00:00:00

abstract：BACKGROUND:It is often difficult to diagnose inflammatory bowel disease (IBD)-associated neoplasia endoscopically due to background inflammation. In addition, due to the absence of sensitive tumor biomarkers, countermeasures against IBD-associated neoplasia are crucial. The purpose of this study is to develop a new dia...

journal_title：BMC cancer

authors： Kinugasa H,Hiraoka S,Nouso K,Yamamoto S,Hirai M,Terasawa H,Yasutomi E,Oka S,Ohmori M,Yamasaki Y,Inokuchi T,Takahara M,Harada K,Tanaka T,Okada H

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:To provide estimations of partial and total prevalence of 24 cancer sites in France in 2008. The estimations of partial prevalence were compared with the previous estimations for 2002. METHODS:Nationwide estimations of incidence and survival data from cancer registries were used for partial prevalence. Nati...

journal_title：BMC cancer

authors： Colonna M,Mitton N,Bossard N,Belot A,Grosclaude P,French Network of Cancer Registries (FRANCIM).

更新日期：2015-03-19 00:00:00

abstract：BACKGROUND:The scientific and public debate concerning organized mammography screening is unprecedentedly strong. With research evidence concerning its efficacy being ambiguous, the recommendations pertaining to the age-thresholds for program inclusion vary between - and even within - countries. Data shows that young w...

journal_title：BMC cancer

authors： Labrie NH,Ludolph R,Schulz PJ

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain. METHODS:Within the EPIC cohort, Cox proportional hazards models were used to describe the relationships of reproductive factors (menarcheal age, time between menarche and first pregnancy, parity, num...

journal_title：BMC cancer

authors： Ritte R,Tikk K,Lukanova A,Tjønneland A,Olsen A,Overvad K,Dossus L,Fournier A,Clavel-Chapelon F,Grote V,Boeing H,Aleksandrova K,Trichopoulou A,Lagiou P,Trichopoulos D,Palli D,Berrino F,Mattiello A,Tumino R,Sacerdote

更新日期：2013-12-09 00:00:00

abstract：BACKGROUND:Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer that is thought to be a precursor to most invasive and metastatic breast cancers. Understanding the mechanisms regulating the invasive transition of DCIS is critical in order to better understand how some types of DCIS become invasive. W...

journal_title：BMC cancer

authors： Bischel LL,Beebe DJ,Sung KE

更新日期：2015-01-21 00:00:00

abstract：BACKGROUND:Several lines of evidence indicate that Sirt1, a class III histone deacetylase (HDAC) is implicated in the initiation and progression of malignancies and thus gained attraction as druggable target. Since data on the role of Sirt1 in pancreatic ductal adenocarcinoma (PDAC) are sparse, we investigated the expr...

journal_title：BMC cancer

authors： Stenzinger A,Endris V,Klauschen F,Sinn B,Lorenz K,Warth A,Goeppert B,Ehemann V,Muckenhuber A,Kamphues C,Bahra M,Neuhaus P,Weichert W

更新日期：2013-10-02 00:00:00

abstract：BACKGROUND:Tamoxifen has dramatically reduced the recurrence and mortality rate of estrogen receptor positive breast cancer. However, the efficacy of tamoxifen varies between individuals and 40% of patients will have a recurrence despite adjuvant tamoxifen treatment. Factors that predict tamoxifen efficacy would be hel...

journal_title：BMC cancer

authors： Jager NG,Koornstra RH,Vincent AD,van Schaik RH,Huitema AD,Korse TM,Schellens JH,Linn SC,Beijnen JH

更新日期：2013-12-28 00:00:00

abstract：BACKGROUND:Patients with cancer of unknown primary account for 10% of patients with metastatic spinal cord compression (MSCC). This retrospective study was performed to identify prognostic factors for functional outcome, local control of MSCC, and survival in 175 of such patients treated with radiotherapy alone. METHO...

journal_title：BMC cancer

authors： Douglas S,Huttenlocher S,Bajrovic A,Rudat V,Schild SE,Rades D

更新日期：2012-06-21 00:00:00

abstract：BACKGROUND:Racial disparities are well-documented in preventive cancer care, but they have not been fully explored in the context of lung cancer screening. We sought to explore racial differences in lung cancer screening outcomes within a lung cancer screening program (LCSP) at our urban academic medical center includi...

journal_title：BMC cancer

authors： Lake M,Shusted CS,Juon HS,McIntire RK,Zeigler-Johnson C,Evans NR,Kane GC,Barta JA

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:Mammalian target of rapamycin (mTOR) inhibitors have anti-tumor effects against renal cell carcinoma, pancreatic neuroendocrine cancer and breast cancer. In this study, we analyzed the antitumor effects of mTOR inhibitors in small cell lung cancer (SCLC) cells and sought to clarify the mechanism of resistanc...

journal_title：BMC cancer

authors： Matsumoto M,Seike M,Noro R,Soeno C,Sugano T,Takeuchi S,Miyanaga A,Kitamura K,Kubota K,Gemma A

更新日期：2015-04-09 00:00:00