当前位置： SCI文献检索 > NeuroImage-Clinical期刊下所有文献 > Structural connectomics of anxious arousal in early adolescence: Translating clinical and ethological findings.

Structural connectomics of anxious arousal in early adolescence: Translating clinical and ethological findings.

Abstract：

:Etiological explanations of clinical anxiety can be advanced through understanding the neural mechanisms associated with anxiety in youth prior to the emergence of psychopathology. In this vein, the present study sought to investigate how trait anxiety is related to features of the structural connectome in early adolescence. 40 adolescents (21 female, mean age = 13.49 years) underwent a diffusion-weighted imaging scan. We hypothesized that the strength of several a priori defined structural connections would vary with anxious arousal based on previous work in human clinical neuroscience and adult rodent optogenetics. First, connection strength of caudate to rostral middle frontal gyrus was predicted to be anticorrelated with anxious arousal, predicated on extant work in clinically-diagnosed adolescents. Second, connection strength of amygdala to rostral anterior cingulate and to medial orbital frontal cortex would be positively and negatively correlated with anxious arousal, respectively, predicated on rodent optogenetics showing the former pathway is anxiogenic and the latter is anxiolytic. We also predicted that levels of anxiety would not vary with measures of global network topology, based on reported null findings. Results support that anxiety in early adolescence is associated with (1) the clinical biomarker connecting caudate to frontal cortex, and (2) the anxiogenic pathway connecting amygdala to rostral anterior cingulate, both in left but not right hemisphere. Findings support that in early adolescence, anxious arousal may be related to mechanisms that increase anxiogenesis, and not in a deficit in regulatory mechanisms that support anxiolysis.

journal_name

Neuroimage Clin

journal_title

NeuroImage. Clinical

authors

Sharp PB,Telzer EH

doi

10.1016/j.nicl.2017.09.012

subject

Has Abstract

pub_date

2017-09-21 00:00:00

pages

604-609

issn

2213-1582

pii

S2213-1582(17)30226-7

journal_volume

16

pub_type

杂志文章

相关文献

NeuroImage-Clinical文献大全
  • Relative contributions of lesion location and lesion size to predictions of varied language deficits in post-stroke aphasia.

    abstract：:Despite the widespread use of lesion-symptom mapping (LSM) techniques to study associations between location of brain damage and language deficits, the prediction of language deficits from lesion location remains a substantial challenge. The present study examined several factors which may impact lesion-symptom predic...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.10.017

    authors： Thye M,Mirman D

    更新日期：2018-01-01 00:00:00

  • Neurocognitive and neuroanatomical maturation in the clinical high-risk states for psychosis: A pattern recognition study.

    abstract：BACKGROUND:Findings from neurodevelopmental studies indicate that adolescents with psychosis spectrum disorders have delayed neurocognitive performance relative to the maturational state of their healthy peers. Using machine learning, we generated a model of neurocognitive age in healthy adults and investigated whether...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.101624

    authors： Kambeitz-Ilankovic L,Haas SS,Meisenzahl E,Dwyer DB,Weiske J,Peters H,Möller HJ,Falkai P,Koutsouleris N

    更新日期：2019-01-01 00:00:00

  • Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography.

    abstract：BACKGROUND:Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of t...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.03.009

    authors： Chen Z,Tie Y,Olubiyi O,Rigolo L,Mehrtash A,Norton I,Pasternak O,Rathi Y,Golby AJ,O'Donnell LJ

    更新日期：2015-03-20 00:00:00

  • Sensory and cross-network contributions to response inhibition in patients with schizophrenia.

    abstract：:Patients with schizophrenia show response inhibition deficits equal to or greater than those seen in impulse-control disorders, and these deficits contribute to poor outcome. However, little is known about the circuit abnormalities underlying this impairment. To address this, we examined stop signal task performance i...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.01.001

    authors： Hoptman MJ,Parker EM,Nair-Collins S,Dias EC,Ross ME,DiCostanzo JN,Sehatpour P,Javitt DC

    更新日期：2018-01-06 00:00:00

  • Impact of chronic migraine attacks and their severity on the endogenous μ-opioid neurotransmission in the limbic system.

    abstract：OBJECTIVE:To evaluate, in vivo, the impact of ongoing chronic migraine (CM) attacks on the endogenous μ-opioid neurotransmission. BACKGROUND:CM is associated with cognitive-emotional dysfunction. CM is commonly associated with frequent acute medication use, including opioids. METHODS:We scanned 15 migraine patients d...

    journal_title：NeuroImage. Clinical

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.nicl.2019.101905

    authors： Jassar H,Nascimento TD,Kaciroti N,DosSantos MF,Danciu T,Koeppe RA,Smith YR,Bigal ME,Porreca F,Casey KL,Zubieta JK,DaSilva AF

    更新日期：2019-01-01 00:00:00

  • Brain functional networks become more connected as amyotrophic lateral sclerosis progresses: a source level magnetoencephalographic study.

    abstract：:This study hypothesizes that the brain shows hyper connectedness as amyotrophic lateral sclerosis (ALS) progresses. 54 patients (classified as "early stage" or "advanced stage") and 25 controls underwent magnetoencephalography and MRI recordings. The activity of the brain areas was reconstructed, and the synchronizati...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.08.001

    authors： Sorrentino P,Rucco R,Jacini F,Trojsi F,Lardone A,Baselice F,Femiano C,Santangelo G,Granata C,Vettoliere A,Monsurrò MR,Tedeschi G,Sorrentino G

    更新日期：2018-08-04 00:00:00

  • Insight and emotion regulation in schizophrenia: A brain activation and functional connectivity study.

    abstract：BACKGROUND:Insight is impaired in the majority of schizophrenia patients. The exact neural correlates of impaired insight remain unclear. We assume that the ability to regulate emotions contributes to having good clinical insight, as patients should be able to regulate their emotional state in such a way that they can ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.09.009

    authors： Larabi DI,van der Meer L,Pijnenborg GHM,Ćurčić-Blake B,Aleman A

    更新日期：2018-01-01 00:00:00

  • Cerebellar degeneration affects cortico-cortical connectivity in motor learning networks.

    abstract：:The cerebellum plays an important role in motor learning as part of a cortico-striato-cerebellar network. Patients with cerebellar degeneration typically show impairments in different aspects of motor learning, including implicit motor sequence learning. How cerebellar dysfunction affects interactions in this cortico-...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.07.012

    authors： Tzvi E,Zimmermann C,Bey R,Münte TF,Nitschke M,Krämer UM

    更新日期：2017-07-15 00:00:00

  • Corrigendum to "Medical image analysis methods in MR/CT-imaged acute-subacute ischemic stroke lesion: Segmentation, prediction and insights into dynamic evolution simulation models. A critical appraisal" [NeuroImage: Clinical 1 (2012) 164-178].

    abstract：:[This corrects the article DOI: 10.1016/j.nicl.2012.10.003.]. ...

    journal_title：NeuroImage. Clinical

    pub_type： 已发布勘误

    doi：10.1016/j.nicl.2013.04.013

    authors： Rekik I,Allassonnière S,Carpenter TK,Wardlaw JM

    更新日期：2013-05-02 00:00:00

  • Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients.

    abstract：:Sickle cell disease (SCD) is a life-threatening genetic condition. Patients suffer from chronic systemic and cerebral vascular disease that leads to early and cumulative neurological damage. Few studies have quantified the effects of this disease on brain morphometry and even fewer efforts have been devoted to older p...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.04.023

    authors： Choi S,Bush AM,Borzage MT,Joshi AA,Mack WJ,Coates TD,Leahy RM,Wood JC

    更新日期：2017-04-29 00:00:00

  • Structural brain differences in pre-adolescents who persist in and recover from stuttering.

    abstract：BACKGROUND:Stuttering is a complex speech fluency disorder occurring in childhood. In young children, stuttering has been associated with speech-related auditory and motor areas of the brain. During transition into adolescence, the majority of children who stutter (75-80%) will experience remission of their symptoms. T...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2020.102334

    authors： Koenraads SPC,van der Schroeff MP,van Ingen G,Lamballais S,Tiemeier H,Baatenburg de Jong RJ,White T,Franken MC,Muetzel RL

    更新日期：2020-01-01 00:00:00

  • Identifying preclinical vascular dementia in symptomatic small vessel disease using MRI.

    abstract：:Sporadic cerebral small vessel disease is an important cause of vascular dementia, a syndrome of cognitive impairment together with vascular brain damage. At post-mortem pure vascular dementia is rare, with evidence of co-existing Alzheimer's disease pathology in 95% of cases. This work used MRI to characterize struct...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.06.023

    authors： Lambert C,Zeestraten E,Williams O,Benjamin P,Lawrence AJ,Morris RG,Mackinnon AD,Barrick TR,Markus HS

    更新日期：2018-06-20 00:00:00

  • Novel surface features for automated detection of focal cortical dysplasias in paediatric epilepsy.

    abstract：:Focal cortical dysplasia is a congenital abnormality of cortical development and the leading cause of surgically remediable drug-resistant epilepsy in children. Post-surgical outcome is improved by presurgical lesion detection on structural MRI. Automated computational techniques have improved detection of focal corti...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.12.030

    authors： Adler S,Wagstyl K,Gunny R,Ronan L,Carmichael D,Cross JH,Fletcher PC,Baldeweg T

    更新日期：2016-12-30 00:00:00

  • Association between migraine frequency and neural response to emotional faces: An fMRI study.

    abstract：:Previous studies have demonstrated that migraine is associated with enhanced perception and altered cerebral processing of sensory stimuli. More recently, it has been suggested that this sensory hypersensitivity might reflect a more general enhanced response to aversive emotional stimuli. Using functional magnetic res...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101790

    authors： Szabó E,Galambos A,Kocsel N,Édes AE,Pap D,Zsombók T,Kozák LR,Bagdy G,Kökönyei G,Juhász G

    更新日期：2019-01-01 00:00:00

  • Whole-brain analytic measures of network communication reveal increased structure-function correlation in right temporal lobe epilepsy.

    abstract：:The in vivo structure-function relationship is key to understanding brain network reorganization due to pathologies. This relationship is likely to be particularly complex in brain network diseases such as temporal lobe epilepsy, in which disturbed large-scale systems are involved in both transient electrical events a...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.05.010

    authors： Wirsich J,Perry A,Ridley B,Proix T,Golos M,Bénar C,Ranjeva JP,Bartolomei F,Breakspear M,Jirsa V,Guye M

    更新日期：2016-05-19 00:00:00

  • Assessment of longitudinal hippocampal atrophy in the first year after ischemic stroke using automatic segmentation techniques.

    abstract：:We assessed first-year hippocampal atrophy in stroke patients and healthy controls using manual and automated segmentations: AdaBoost, FIRST (fsl/v5.0.8), FreeSurfer/v5.3 and v6.0, and Subfields (in FreeSurfer/v6.0). We estimated hippocampal volumes in 39 healthy controls and 124 stroke participants at three months, a...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.102008

    authors： Khlif MS,Werden E,Egorova N,Boccardi M,Redolfi A,Bird L,Brodtmann A

    更新日期：2019-01-01 00:00:00

  • Data fusion detects consistent relations between non-lesional white matter myelin, executive function, and clinical characteristics in multiple sclerosis.

    abstract：:We examined the influence of dysfunctional, non-lesional white matter on cognitive performance in multiple sclerosis (MS). Forty-six MS subjects were assessed using MRI-based myelin water imaging (MWI), and average myelin water fraction (MWF) values across 20 white matter regions of interest (ROIs) were determined. A ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101926

    authors： Baumeister TR,Lin SJ,Vavasour I,Kolind S,Kosaka B,Li DKB,Traboulsee A,MacKay A,McKeown MJ

    更新日期：2019-01-01 00:00:00

  • Neural correlates of cognitive function and symptoms in attention-deficit/hyperactivity disorder in adults.

    abstract：:While gray matter (GM) anomalies have been reported for attention-deficit/hyperactivity disorder (ADHD), investigating their associations with cognitive deficits and individual symptom domains can help pinpoint the neural underpinnings critical for the pathology of ADHD, particularly the persist form of ADHD. In this ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.04.035

    authors： Duan K,Chen J,Calhoun VD,Lin D,Jiang W,Franke B,Buitelaar JK,Hoogman M,Arias-Vasquez A,Turner JA,Liu J

    更新日期：2018-05-02 00:00:00

  • Damage to white matter bottlenecks contributes to language impairments after left hemispheric stroke.

    abstract：:Damage to the white matter underlying the left posterior temporal lobe leads to deficits in multiple language functions. The posterior temporal white matter may correspond to a bottleneck where both dorsal and ventral language pathways are vulnerable to simultaneous damage. Damage to a second putative white matter bot...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.02.019

    authors： Griffis JC,Nenert R,Allendorfer JB,Szaflarski JP

    更新日期：2017-02-24 00:00:00

  • Disrupted structural connectivity of fronto-deep gray matter pathways in progressive supranuclear palsy.

    abstract：BACKGROUND:Structural connectivity is a promising methodology to detect patterns of neural network dysfunction in neurodegenerative diseases. This approach has not been tested in progressive supranuclear palsy (PSP). OBJECTIVES:The aim of this study is reconstructing the structural connectome to characterize and detec...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101899

    authors： Abos A,Segura B,Baggio HC,Campabadal A,Uribe C,Garrido A,Camara A,Muñoz E,Valldeoriola F,Marti MJ,Junque C,Compta Y

    更新日期：2019-01-01 00:00:00

  • MRI and cognitive scores complement each other to accurately predict Alzheimer's dementia 2 to 7 years before clinical onset.

    abstract：BACKGROUND:Predicting cognitive decline and the eventual onset of dementia in patients with Mild Cognitive Impairment (MCI) is of high value for patient management and potential cohort enrichment in pharmaceutical trials. We used cognitive scores and MRI biomarkers from a single baseline visit to predict the onset of d...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.102121

    authors： Zandifar A,Fonov VS,Ducharme S,Belleville S,Collins DL,Alzheimer’s Disease Neuroimaging Initiative.

    更新日期：2020-01-01 00:00:00

  • Thalamic functional connectivity predicts seizure laterality in individual TLE patients: application of a biomarker development strategy.

    abstract：:Noninvasive markers of brain function could yield biomarkers in many neurological disorders. Disease models constrained by coordinate-based meta-analysis are likely to increase this yield. Here, we evaluate a thalamic model of temporal lobe epilepsy that we proposed in a coordinate-based meta-analysis and extended in ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2014.08.002

    authors： Barron DS,Fox PT,Pardoe H,Lancaster J,Price LR,Blackmon K,Berry K,Cavazos JE,Kuzniecky R,Devinsky O,Thesen T

    更新日期：2014-08-07 00:00:00

  • Multivariate pattern analysis strategies in detection of remitted major depressive disorder using resting state functional connectivity.

    abstract：:Understanding abnormal resting-state functional connectivity of distributed brain networks may aid in probing and targeting mechanisms involved in major depressive disorder (MDD). To date, few studies have used resting state functional magnetic resonance imaging (rs-fMRI) to attempt to discriminate individuals with MD...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.02.018

    authors： Bhaumik R,Jenkins LM,Gowins JR,Jacobs RH,Barba A,Bhaumik DK,Langenecker SA

    更新日期：2016-03-02 00:00:00

  • Conflict processing in juvenile patients with neurofibromatosis type 1 (NF1) and healthy controls - Two pathways to success.

    abstract：:Neurofibromatosis Type 1 (NF1) is a monogenetic autosomal-dominant disorder with a broad spectrum of clinical symptoms and is commonly associated with cognitive deficits. Patients with NF1 frequently exhibit cognitive impairments like attention problems, working memory deficits and dysfunctional inhibitory control. Th...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.02.014

    authors： Bluschke A,von der Hagen M,Papenhagen K,Roessner V,Beste C

    更新日期：2017-02-20 00:00:00

  • Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis.

    abstract：Background:The aim of this study was to investigate the potential of combined textural feature analysis of contrast-enhanced MRI (CE-MRI) and static O-(2-[18F]fluoroethyl)-L-tyrosine (FET) PET for the differentiation between local recurrent brain metastasis and radiation injury since CE-MRI often remains inconclusive. ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.08.024

    authors： Lohmann P,Kocher M,Ceccon G,Bauer EK,Stoffels G,Viswanathan S,Ruge MI,Neumaier B,Shah NJ,Fink GR,Langen KJ,Galldiks N

    更新日期：2018-08-19 00:00:00

  • Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities.

    abstract：:The amyloid imaging agent, Pittsburgh Compound-B, binds with high affinity to β-amyloid (Aβ) in the brain, and it is well established that PiB also shows non-specific retention in white matter (WM). However, little is known about retention of PiB in areas of white matter hyperintensities (WMH), abnormalities commonly ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.09.009

    authors： Goodheart AE,Tamburo E,Minhas D,Aizenstein HJ,McDade E,Snitz BE,Price JC,Mathis CA,Lopez OL,Klunk WE,Cohen AD

    更新日期：2015-09-29 00:00:00

  • Metabolic brain networks in aging and preclinical Alzheimer's disease.

    abstract：:Metabolic brain networks can provide insight into the network processes underlying progression from healthy aging to Alzheimer's disease. We explore the effect of two Alzheimer's disease risk factors, amyloid-β and ApoE ε4 genotype, on metabolic brain networks in cognitively normal older adults (N = 64, ages 69-89) co...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.12.037

    authors： Arnemann KL,Stöber F,Narayan S,Rabinovici GD,Jagust WJ

    更新日期：2017-12-28 00:00:00

  • MEG-based detection and localization of perilesional dysfunction in chronic stroke.

    abstract：:Post-stroke impairment is associated not only with structural lesions, but also with dysfunction in surviving perilesional tissue. Previous studies using equivalent current dipole source localization of MEG/EEG signals have demonstrated a preponderance of slow-wave activity localized to perilesional areas. Recent stud...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.03.019

    authors： Chu RK,Braun AR,Meltzer JA

    更新日期：2015-04-08 00:00:00

  • Multiparametric graph theoretical analysis reveals altered structural and functional network topology in Alzheimer's disease.

    abstract：:Alzheimer's disease (AD), an irreversible neurodegenerative disease, is the most common type of dementia in elderly people. This present study incorporated multiple structural and functional connectivity metrics into a graph theoretical analysis framework and investigated alterations in brain network topology in patie...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101680

    authors： Lin SY,Lin CP,Hsieh TJ,Lin CF,Chen SH,Chao YP,Chen YS,Hsu CC,Kuo LW

    更新日期：2019-01-01 00:00:00

  • Alzheimer's disease patients activate attention networks in a short-term memory task.

    abstract：:Network functioning during cognitive tasks is of major interest in Alzheimer's disease (AD). Cognitive functioning in AD includes variable performance in short-term memory (STM). In most studies, the verbal STM functioning in AD patients has been interpreted within the phonological loop subsystem of Baddeley's working...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101892

    authors： Kurth S,Bahri MA,Collette F,Phillips C,Majerus S,Bastin C,Salmon E

    更新日期：2019-01-01 00:00:00