Abstract:
OBJECTIVE:The evaluation of discomfort in paediatric research is scarcely evidence-based. In this study, we make a start in describing children's self-reported discomfort during common medical research procedures and compare this with discomfort during dental check-ups which can be considered as a reference level of a 'minimal discomfort' medical procedure. We exploratory study whether there are associations between age, anxiety-proneness, gender, medical condition, previous experiences and discomfort. We also describe children's suggestions for reducing discomfort. DESIGN:Cross-sectional descriptive study. SETTING:Paediatric research at three academic hospitals. PATIENTS:357 children with and without illnesses (8-18 years, mean=10.6 years) were enrolled: 307 from paediatric research studies and 50 from dental care. MAIN OUTCOME MEASURES:We measured various generic forms of discomfort (nervousness, annoyance, pain, fright, boredom, tiredness) due to six common research procedures: buccal swabs, MRI scans, pulmonary function tests, skin prick tests, ultrasound imaging and venepunctures. RESULTS:Most children reported limited discomfort during the research procedures (means: 1-2.6 on a scale from 1 to 5). Compared with dental check-ups, buccal swab tests, skin prick tests and ultrasound imaging were less discomforting, while MRI scans, venepunctures and pulmonary function tests caused a similar degree of discomfort. 60.3% of the children suggested providing distraction by showing movies to reduce discomfort. The exploratory analyses suggested a positive association between anxiety-proneness and discomfort. CONCLUSIONS:The findings of this study support the acceptability of participation of children in the studied research procedures, which stimulates evidence-based research practice. Furthermore, the present study can be considered as a first step in providing benchmarks for discomfort of procedures in paediatric research.
journal_name
BMJ Openjournal_title
BMJ openauthors
Staphorst MS,Benninga MA,Bisschoff M,Bon I,Busschbach JJV,Diederen K,van Goudoever JB,Haarman EG,Hunfeld JAM,Jaddoe VVW,de Jong KJM,de Jongste JC,Kindermann A,Königs M,Oosterlaan J,Passchier J,Pijnenburg MW,Reneman L,doi
10.1136/bmjopen-2017-016077subject
Has Abstractpub_date
2017-08-01 00:00:00pages
e016077issue
7issn
2044-6055pii
bmjopen-2017-016077journal_volume
7pub_type
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