Abstract:
BACKGROUND:Over 60 % of human emerging infectious diseases are zoonotic, and there is growing evidence of the zooanthroponotic transmission of diseases from humans to livestock and wildlife species, with major implications for public health, economics, and conservation. Zooanthroponoses are of relevance to critically endangered species; amongst these is the mountain gorilla (Gorilla beringei beringei) of Uganda. Here, we assess the occurrence of Cryptosporidium, Cyclospora, Giardia, and Entamoeba infecting mountain gorillas in the Bwindi Impenetrable National Park (BINP), Uganda, using molecular methods. We also assess the occurrence of these parasites in humans and livestock species living in overlapping/adjacent geographical regions. RESULTS:Diagnostic PCR detected Cryptosporidium parvum in one sample from a mountain gorilla (IIdA23G2) and one from a goat (based on SSU). Cryptosporidium was not detected in humans or cattle. Cyclospora was not detected in any of the samples analysed. Giardia was identified in three human and two cattle samples, which were linked to assemblage A, B and E of G. duodenalis. Sequences defined as belonging to the genus Entamoeba were identified in all host groups. Of the 86 sequence types characterised, one, seven and two have been recorded previously to represent genotypes of Cryptosporidium, Giardia, and Entamoeba, respectively, from humans, other mammals, and water sources globally. CONCLUSIONS:This study provides a snapshot of the occurrence and genetic make-up of selected protists in mammals in and around BINP. The genetic analyses indicated that 54.6% of the 203 samples analysed contained parasites that matched species, genotypes, or genetic assemblages found globally. Seventy-six new sequence records were identified here for the first time. As nothing is known about the zoonotic/zooanthroponotic potential of the corresponding parasites, future work should focus on wider epidemiological investigations together with continued surveillance of all parasites in humans, other mammals, the environment, and water in this highly impoverished area.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Nolan MJ,Unger M,Yeap YT,Rogers E,Millet I,Harman K,Fox M,Kalema-Zikusoka G,Blake DPdoi
10.1186/s13071-017-2283-5subject
Has Abstractpub_date
2017-07-18 00:00:00pages
340issue
1issn
1756-3305pii
10.1186/s13071-017-2283-5journal_volume
10pub_type
杂志文章abstract:BACKGROUND:In 2011, we reported occurrence of natural human infections with Brugia pahangi, a filarial worm of dogs and cats, in a surburb of Kuala Lumpur, the capital city of Malaysia. Our preliminary entomological survey at that time suggested the mosquito species Armigeres subalbatus as the vector of the zoonotic in...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-219
更新日期:2013-07-30 00:00:00
abstract:BACKGROUND:Phlebotomine sand flies are dipterans of the family Psychodidae. They are very important to veterinary medicine because some species are vectors of infective forms of Leishmania spp., the etiological agents of leishmaniasis. The Parque Estadual do Rio Doce is located in an area with constant reports of cases...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-1227-1
更新日期:2015-12-02 00:00:00
abstract:BACKGROUND:Toxoplasmosis is an important zoonosis, being a cause of congenital disease and abortion in animals and humans. DNA vaccination as a promising vaccine remains a challenge for an improved delivery system. METHODS:In this study, attenuated Salmonella typhimurium BRD509 was used to deliver a DNA vaccine encodi...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-145
更新日期:2014-03-31 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3837-5
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abstract:BACKGROUND:Knowledge of insecticide resistance status in the main malaria vectors is an essential component of effective malaria vector control. This study presents the first evaluation of the status of insecticide resistance in Anopheles gambiae populations from Bangui, the Central African Republic. METHODS:Anopheles...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1965-8
更新日期:2017-01-13 00:00:00
abstract::Here we describe a case of paediatric visceral leishmaniasis recorded in an infant initially suspected for acute lymphoblastic leukaemia due to the clinical and haematological presentation. Eventually the patient was found positive for Leishmania infantum infection and successfully treated. This case emphasises how pi...
journal_title:Parasites & vectors
pub_type: 信件
doi:10.1186/1756-3305-6-123
更新日期:2013-04-29 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3401-3
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abstract:BACKGROUND:Hepatocellular carcinoma-associated antigen 59 (HCA59), which is one of the most important excretory/secretory products of Haemonchus contortus (HcESPs), is known to have antigenic functions. However, its immunomodulatory effects on host cells are poorly understood. METHODS:Here, we cloned the HCA59 gene an...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3375-1
更新日期:2019-03-14 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1778-9
更新日期:2016-09-29 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-29
更新日期:2012-02-08 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-136
更新日期:2012-07-09 00:00:00
abstract:BACKGROUND:In Morocco, the main strategies of leishmaniasis vector control are based on environmental modifications. Use of local residual indoor spraying with synthetic pyrethroids is often envisaged. The need to evaluate this control method is essential. The current study was conducted to determine the efficacy of an...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-354
更新日期:2013-12-13 00:00:00
abstract:BACKGROUND:This study was carried out to develop a health education learning package (HELP) about soil-transmitted helminth (STH) infections, and to evaluate what impact such a package could have in terms of reducing the incidence and intensity of STH infections among Orang Asli schoolchildren in Pahang, Malaysia. MET...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-416
更新日期:2014-09-02 00:00:00
abstract:BACKGROUND:Leishmaniasis is a major parasitic disease worldwide, except in Australia and Antarctica, and it poses a significant public health problem. Due to the absence of safe and effective vaccines and drugs, researchers have begun an extensive search for new drugs. The aim of the current study was to investigate th...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04543-y
更新日期:2021-01-11 00:00:00
abstract:BACKGROUND:The role of endemic murid rodents as hosts of arthropod vectors of diseases of medical and veterinary significance is well established in the northern hemisphere. In contrast, endemic murids are comparatively understudied as vector hosts in Africa, particularly in South Africa. Considering the great rodent d...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-366
更新日期:2014-08-15 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-246
更新日期:2012-10-31 00:00:00
abstract:BACKGROUND:Tannin-rich plants have been examined as an alternative for controlling the gastrointestinal nematodes in ruminants. In vivo assays typically examine the anthelmintic activity in female fecundity and/or the adult worm burden, without considering other life-cycle stages or the impact on pasture contamination....
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1370-3
更新日期:2016-02-24 00:00:00
abstract:BACKGROUND:Schistosomiasis japonica remains a major public health problem in China. Integrating molecular analyses, such as population genetic analyses, of the parasite into the on-going surveillance programs is helpful in exploring the factors causing the persistence and/or spread of Schistosoma japonicum. However, ge...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-1074-0
更新日期:2015-09-08 00:00:00
abstract:BACKGROUND:Zoonotic onchocerciasis is a vector-borne disease, which involves many animal species, including large ungulates, boars, dogs, and sporadically, humans. So far, 39 cases of zoonotic onchocerciasis have been reported worldwide, 30 of which have been found in the last 20 years. Onchocerca nematodes are transmi...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-3925-6
更新日期:2020-02-12 00:00:00
abstract:BACKGROUND:The Lowland tapir (Tapirus terrestris) is the largest Brazilian mammal and despite being distributed in various Brazilian biomes, it is seriously endangered in the Atlantic Rainforest. These hosts were never evaluated for the presence of Trypanosoma parasites. METHODS:The Lowland tapirs were captured in the...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-349
更新日期:2013-12-11 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-124
更新日期:2014-03-25 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2556-z
更新日期:2017-12-27 00:00:00
abstract::The Companion Vector-Borne Diseases (CVBD) World Forum is a working group of leading international experts who meet annually to evaluate current scientific findings and future trends concerning the distribution, pathogenesis, clinical presentation, diagnosis and prevention of vector-borne infections of dogs and cats. ...
journal_title:Parasites & vectors
pub_type: 信件
doi:10.1186/s13071-020-04407-5
更新日期:2020-11-10 00:00:00
abstract:BACKGROUND:Whipworms (Nematoda: Trichuridae), among the most common soil-transmitted helminths (STHs), can cause the socioeconomically important disease trichuriasis in various mammalian hosts including humans and non-human primates. For many years, Trichuris from non-human primates has been assigned to the same specie...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3100-5
更新日期:2018-09-20 00:00:00
abstract:BACKGROUND:Helminth neuroinfections represent a serious health problem, but host immune mechanisms in the nervous tissue often remain undiscovered. This study aims at in vitro characterization of the response of murine astrocytes and microglia exposed to Trichobilharzia regenti which is a neuropathogenic schistosome mi...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1869-7
更新日期:2016-11-14 00:00:00
abstract:BACKGROUND:The bacteria Anaplasma platys and Ehrlichia canis and the protozoan Leishmania infantum are vector-borne agents that cause canine vector-borne diseases, some of which are zoonotic. The present survey investigated the prevalence of Anaplasma, Ehrlichia and Leishmania in red foxes (Vulpes vulpes) from Portugal...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0756-y
更新日期:2015-03-23 00:00:00
abstract:BACKGROUND:Human and animal fascioliasis poses serious public health problems in South America. In Venezuela, livestock infection represents an important veterinary problem whereas there appear to be few human cases reported, most of which are passively detected in health centres. However, results of recent surveys sug...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-200
更新日期:2011-10-14 00:00:00
abstract:BACKGROUND:Acanthamoebiasis is most often found in patients with immune deficiency, with infections facilitated by the intake of immunosuppressive drugs. The host immune response to Acanthamoeba spp. infection is poorly understood. Thus, in this study, we aimed to examine the course of Acanthamoeba spp. infection takin...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3108-x
更新日期:2018-09-20 00:00:00
abstract:BACKGROUND:Novel transgenic mosquito control methods require progressively more realistic evaluation. The goal of this study was to determine the effect of a transgene that causes a male-bias sex ratio on Anopheles gambiae target populations in large insectary cages. METHODS:Life history characteristics of Anopheles g...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3289-y
更新日期:2019-02-06 00:00:00
abstract:BACKGROUND:Ov16 serology is considered a reference method for Onchocerca volvulus epidemiological mapping. Given the suboptimal sensitivity of this test and the fact that seroconversion takes more than a year after infection, additional serological tests might be needed to guide onchocerciasis elimination programmes. R...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3308-z
更新日期:2019-01-28 00:00:00