Impact of postoperative daily image-guided intensity-modulated radiotherapy on overall and local progression-free survival in patients with oral cavity cancer.

abstract：BACKGROUND:For gastric cancer patients, surgical resection with en-bloc lymphadenectomy is the cornerstone of curative treatment. Open gastrectomy has long been the preferred surgical approach worldwide. However, this procedure is associated with considerable morbidity. Several meta-analyses have shown an advantage in ...

journal_title：BMC cancer

authors： Haverkamp L,Brenkman HJ,Seesing MF,Gisbertz SS,van Berge Henegouwen MI,Luyer MD,Nieuwenhuijzen GA,Wijnhoven BP,van Lanschot JJ,de Steur WO,Hartgrink HH,Stoot JH,Hulsewé KW,Spillenaar Bilgen EJ,Rütter JE,Kouwenhoven EA,van

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the most aggressive cancers lacking efficient early detection biomarkers. Circulating miRNAs are now being considered to have potency to be used as diagnostic and prognostic biomarkers in different diseases as well as cancers. In case of cancer,...

journal_title：BMC cancer

authors： Chhatriya B,Mukherjee M,Ray S,Sarkar P,Chatterjee S,Nath D,Das K,Goswami S

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:18F-FDG PET/CT could satisfactorily show pancreatic and extra-pancreatic lesions in AIP, which can be mistaken for pancreatic cancer (PC). This study aimed to identify 18F-FDG PET/CT findings that might differentiate AIP from PC. METHODS:FDG-PET/CT findings of 26 AIP and 40 PC patients were reviewed. Pancre...

journal_title：BMC cancer

authors： Zhang J,Jia G,Zuo C,Jia N,Wang H

更新日期：2017-10-23 00:00:00

abstract：BACKGROUND:Patients undergone kidney transplantation present higher risk of Urothelial Carcinoma (UC) development and represent a subgroup of special interest. To date, vinflunine is the only drug approved in Europe for the treatment of advanced UC after failure of platinum-based chemotherapy. However, to our knowledge...

journal_title：BMC cancer

authors： Bordi P,Tiseo M,Baldari G,Buti S

更新日期：2016-08-12 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GIST), one of the most common mesenchymal tumors of the gastrointestinal tract, prior to routine immunohistochemical staining and the introduction of tyrosine kinase inhibitors, were often mistaken for neoplasms of smooth muscle origin such as leiomyomas, leiomyosarcomas or l...

journal_title：BMC cancer

authors： Call J,Walentas CD,Eickhoff JC,Scherzer N

更新日期：2012-03-19 00:00:00

abstract：BACKGROUND:We evaluated possible diagnostic and prognostic values of serum midkine in malignant pleural mesothelioma in comparison with those of serum mesothelin, a well-established diagnostic biomarker. METHODS:Serum mesothelin and midkine levels were determined with an enzyme-linked immunosorbent assay. We examined ...

journal_title：BMC cancer

authors： Ak G,Tada Y,Shimada H,Metintas S,Ito M,Hiroshima K,Tagawa M,Metintas M

更新日期：2017-03-23 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a type of neoplasm that is highly prevalent in East Asia and Africa with Epstein-Barr virus (EBV), genetic, and dietary factors implicated as possible aetiologic factors. Previous studies suggested the association of certain cytokines with the invasion and metastatic propert...

journal_title：BMC cancer

authors： Chew MM,Gan SY,Khoo AS,Tan EL

更新日期：2010-10-22 00:00:00

abstract：BACKGROUND:XELOX (capecitabine + oxaliplatin) and FOLFOX 4 (5-FU + folinic acid + oxaliplatin) have shown similar improvements in survival in patients with metastatic colorectal cancer (MCRC). A US cost-minimization study found that the two regimens had similar costs from a healthcare provider perspective but XELOX had...

journal_title：BMC cancer

authors： Tse VC,Ng WT,Lee V,Lee AW,Chua DT,Chau J,McGhee SM

更新日期：2011-07-09 00:00:00

abstract：BACKGROUND:Ovarian carcinoma is a rarely curable disease, for which new treatment options are required. As agents that block HMG-CoA reductase and the mevalonate pathway, the statin family of drugs are used in the treatment of hypercholesterolemia and have been shown to trigger apoptosis in a tumor-specific manner. Rec...

journal_title：BMC cancer

authors： Martirosyan A,Clendening JW,Goard CA,Penn LZ

更新日期：2010-03-18 00:00:00

abstract：BACKGROUND:Preoperative chemoradiotherapy is the recommended standard of care for patients with local advanced rectal cancer. However, it remains unclear, whether a prolonged time interval to surgery results in an increased perioperative morbidity, reduced TME quality or better pathological response. Aim of this study ...

journal_title：BMC cancer

authors： Lichthardt S,Wagner J,Löb S,Matthes N,Kastner C,Anger F,Germer CT,Wiegering A

更新日期：2020-01-20 00:00:00

abstract：BACKGROUND:Currently the majority of cancer patients are considered ineligible for intensive care treatment and oncologists are struggling to get their patients admitted to intensive care units. Critical care and oncology are frequently two separate worlds that communicate rarely and thus do not share novel development...

journal_title：BMC cancer

authors： von Bergwelt-Baildon M,Hallek MJ,Shimabukuro-Vornhagen AA,Kochanek M

更新日期：2010-11-08 00:00:00

abstract：BACKGROUND:Interpretation of comparative health-related quality of life (HRQOL) studies following different prostate cancer treatments is often difficult due to differing patient ages. Furthermore, age-related changes can hardly be discriminated from therapy-related changes. The evaluation of age-and comorbidity-relate...

journal_title：BMC cancer

authors： Pinkawa M,Fischedick K,Gagel B,Piroth MD,Asadpour B,Klotz J,Borchers H,Jakse G,Eble MJ

更新日期：2009-08-24 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate epigenetic status of cyclin A1 in human papillomavirus-associated cervical cancer. Y. Tokumaru et al., Cancer Res 64, 5982-7 (Sep 1, 2004)demonstrated in head and neck squamous-cell cancer an inverse correlation between cyclin A1 promoter hypermethylation and TP53 mutati...

journal_title：BMC cancer

authors： Kitkumthorn N,Yanatatsanajit P,Kiatpongsan S,Phokaew C,Triratanachat S,Trivijitsilp P,Termrungruanglert W,Tresukosol D,Niruthisard S,Mutirangura A

更新日期：2006-03-08 00:00:00

abstract：BACKGROUND:Studies have consistently indicated that the majority of individuals meeting the US Prevention Services Task Force guidelines for genetic testing have not had genetic counseling or testing. Despite increased availability and lower costs of multiplex cancer gene panels, there remains a gap in genetics service...

journal_title：BMC cancer

authors： Rayes N,Bowen DJ,Coffin T,Nebgen D,Peterson C,Munsell MF,Gavin K,Lechner R,Crase J,Polinsky D,Romero I,Blank SV,Levine DA,Norquist BM,Swisher EM,Lu KH

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:Several studies show that the regulatory impact of microRNAs (miRNAs) is an essential contribution to the pathogenesis of colorectal cancer (CRC). The expression levels of diverse miRNAs are associated with specific clinical diagnoses and prognoses of CRC. However, this association reveals very little action...

journal_title：BMC cancer

authors： Li J,Mansmann UR

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:SLIT-ROBO families of proteins mediate axon pathfinding and their expression is not solely confined to nervous system. Aberrant expression of SLIT-ROBO genes was repeatedly shown in a wide variety of cancers, yet data about their collective behavior in hepatocellular carcinoma (HCC) is missing. Hence, we qua...

journal_title：BMC cancer

authors： Avci ME,Konu O,Yagci T

更新日期：2008-12-29 00:00:00

abstract：BACKGROUND:In Chile, more than 500 women die every year from cervical cancer, and a majority of Chilean women are not up-to-date with their Papanicolau (Pap) test. Mobile health has great potential in many health areas, particularly in health promotion and prevention. There are no randomized controlled trials in Latin ...

journal_title：BMC cancer

authors： Momany MC,Martinez-Gutierrez J,Soto M,Capurro D,Ciampi F,Thompson B,Puschel K

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:This study aims to evaluate the impact of colony stimulating factor-1 (CSF-1) expression on recurrence and survival of patients with clear-cell renal cell carcinoma (ccRCC) following surgery. METHODS:We retrospectively enrolled 267 patients (195 in the training cohort and 72 in the validation cohort) with c...

journal_title：BMC cancer

authors： Yang L,Wu Q,Xu L,Zhang W,Zhu Y,Liu H,Xu J,Gu J

更新日期：2015-02-18 00:00:00

abstract：BACKGROUND:Hypoxia is an important factor that contributes to tumour aggressiveness and correlates with poor prognosis and resistance to conventional therapy. Therefore, identifying hypoxic environments within tumours is extremely useful for understanding cancer biology and developing novel therapeutic strategies. Seve...

journal_title：BMC cancer

authors： Takei N,Yoneda A,Kosaka M,Sakai-Sawada K,Tamura Y

更新日期：2019-05-29 00:00:00

abstract：BACKGROUND:Although cisplatin is one of the most effective chemotherapeutic agents, cisplatin alone does not achieve a satisfactory therapeutic outcome. Also cisplatin accumulation shows toxicity to normal tissues. In this study, we examined the possibility of HemoHIM both to enhance anticancer effect with cisplatin an...

journal_title：BMC cancer

authors： Park HR,Ju EJ,Jo SK,Jung U,Kim SH,Yee ST

更新日期：2009-03-17 00:00:00

abstract：BACKGROUND:The objective of this systematic review and meta-analysis was to determine the prognostic value of total tumor-infiltrating lymphocytes (TILs) and subtypes of TILs (CD4+, CD8+, and FOXP3+) in triple-negative breast cancer (TNBC). METHODS:A systematic search of the MEDLINE, EMBASE, and Web of Science databas...

journal_title：BMC cancer

authors： Gao G,Wang Z,Qu X,Zhang Z

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:To validate the robust predictive values of tumor vascularity and hand-foot-skin reaction (HFSR) in combination treatment of transarterial chemoembolization (TACE) and sorafenib for patients with intermediate hepatocellular carcinoma (HCC), and then select the potential candidates who would survive best from...

journal_title：BMC cancer

authors： Wang E,Xia D,Bai W,Yuan J,Li X,Niu J,Yin Z,Xia J,Cai H,Fan D,Han G,Liu L

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND:High resolution anoscopy (HRA) examination is regarded as the best method for the management of anal high grade squamous intraepithelial lesions to prevent anal squamous carcinoma. However, little is known about the acceptability of this procedure. This analysis looks at patient experience of HRA examination...

journal_title：BMC cancer

authors： De-Masi A,Davis E,Cuming T,Chindawi N,Pesola F,Cappello C,Chambers S,Bowring J,Rosenthal AN,Sasieni P,Nathan M

更新日期：2018-05-11 00:00:00

abstract：BACKGROUND:Breast cancer in women is increasingly frequent, and care is complex, onerous and expensive, all of which lend urgency to improvements in care. Quality measurement is essential to monitor effectiveness and to guide improvements in healthcare. METHODS:Ten databases, including Medline, were searched electroni...

journal_title：BMC cancer

authors： Schachter HM,Mamaladze V,Lewin G,Graham ID,Brouwers M,Sampson M,Morrison A,Zhang L,O'Blenis P,Garritty C

更新日期：2006-12-18 00:00:00

abstract：BACKGROUND:c-Met signaling has been implicated in oncogenesis especially in cells with c-met gene amplification. Since 20 % of gastric cancer patients show high level of c-Met expression, c-Met has been identified as a good candidate for targeted therapy in gastric cancer. Herein, we report our newly synthesized c-Met ...

journal_title：BMC cancer

authors： Park CH,Cho SY,Ha JD,Jung H,Kim HR,Lee CO,Jang IY,Chae CH,Lee HK,Choi SU

更新日期：2016-01-22 00:00:00

abstract：BACKGROUND:Reactivation of hepatitis B or C virus can occur in patients undergoing chemotherapy. Recommendations for selective or systematic hepatitis B virus testing prior chemotherapy for solid tumors differ. The primary aim was to determine the seroprevalence of hepatitis B or C in a low endemic country. The second ...

journal_title：BMC cancer

authors： Brasseur M,Heurgué-Berlot A,Barbe C,Brami C,Rey JB,Vella-Boucaud J,Dabouz F,Deslée G,Grange F,Volet J,Bouché O

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Worldwide, acute leukemia is the most common type of childhood cancer. It is particularly common in the Hispanic populations residing in the United States, Costa Rica, and Mexico City. The objective of this study was to determine the incidence of acute leukemia in children who were diagnosed and treated in p...

journal_title：BMC cancer

authors： Pérez-Saldivar ML,Fajardo-Gutiérrez A,Bernáldez-Ríos R,Martínez-Avalos A,Medina-Sanson A,Espinosa-Hernández L,Flores-Chapa Jde D,Amador-Sánchez R,Peñaloza-González JG,Alvarez-Rodríguez FJ,Bolea-Murga V,Flores-Lujano J,Rodríguez-Z

更新日期：2011-08-17 00:00:00

abstract：BACKGROUND:Compared with World Health Organization-defined acute myeloid leukaemia (AML) not otherwise specified, patients with AML with myelodysplasia-related changes (AML-MRC) are generally older and more likely to have poor-risk cytogenetics, leading to poor response and prognosis. More than one-half of all older (≥...

journal_title：BMC cancer

authors： Seymour JF,Döhner H,Butrym A,Wierzbowska A,Selleslag D,Jang JH,Kumar R,Cavenagh J,Schuh AC,Candoni A,Récher C,Sandhu I,Del Castillo TB,Al-Ali HK,Falantes J,Stone RM,Minden MD,Weaver J,Songer S,Beach CL,Dombret H

更新日期：2017-12-14 00:00:00

abstract：BACKGROUND:The molecular chaperone, heat shock protein 90 (Hsp90) has been shown to be overexpressed in a number of cancers, including prostate cancer, making it an important target for drug discovery. Unfortunately, results with N-terminal inhibitors from initial clinical trials have been disappointing, as toxicity an...

journal_title：BMC cancer

authors： Eskew JD,Sadikot T,Morales P,Duren A,Dunwiddie I,Swink M,Zhang X,Hembruff S,Donnelly A,Rajewski RA,Blagg BS,Manjarrez JR,Matts RL,Holzbeierlein JM,Vielhauer GA

更新日期：2011-10-31 00:00:00

abstract：BACKGROUND:The prognostic value of rectal invasion is still unclear in stage IVA cervical cancer. The objective of this study is to evaluate patient outcome and prognostic factors in stage IVA cervical cancer treated with radiation therapy. METHODS:A retrospective review of the medical records of patients treated with...

journal_title：BMC cancer

authors： Wakatsuki M,Kato S,Kiyohara H,Ohno T,Karasawa K,Tamaki T,Ando K,Shiba S,Kamada T,Nakano T

更新日期：2016-03-23 00:00:00