当前位置： SCI文献检索 > NeuroImage-Clinical期刊下所有文献 > Pain and spinal cord imaging measures in children with demyelinating disease.

Pain and spinal cord imaging measures in children with demyelinating disease.

Abstract：

:Pain is a significant problem in diseases affecting the spinal cord, including demyelinating disease. To date, studies have examined the reliability of clinical measures for assessing and classifying the severity of spinal cord injury (SCI) and also to evaluate SCI-related pain. Most of this research has focused on adult populations and patients with traumatic injuries. Little research exists regarding pediatric spinal cord demyelinating disease. One reason for this is the lack of reliable and useful approaches to measuring spinal cord changes since currently used diagnostic imaging has limited specificity for quantitative measures of demyelination. No single imaging technique demonstrates sufficiently high sensitivity or specificity to myelin, and strong correlation with clinical measures. However, recent advances in diffusion tensor imaging (DTI) and magnetization transfer imaging (MTI) measures are considered promising in providing increasingly useful and specific information on spinal cord damage. Findings from these quantitative imaging modalities correlate with the extent of demyelination and remyelination. These techniques may be of potential use for defining the evolution of the disease state, how it may affect specific spinal cord pathways, and contribute to the management of pediatric demyelination syndromes. Since pain is a major presenting symptom in patients with transverse myelitis, the disease is an ideal model to evaluate imaging methods to define these regional changes within the spinal cord. In this review we summarize (1) pediatric demyelinating conditions affecting the spinal cord; (2) their distinguishing features; and (3) current diagnostic and classification methods with particular focus on pain pathways. We also focus on concepts that are essential in developing strategies for the detection, monitoring, treatment and repair of pediatric myelitis.

journal_name

Neuroimage Clin

journal_title

NeuroImage. Clinical

authors

Barakat N,Gorman MP,Benson L,Becerra L,Borsook D

doi

10.1016/j.nicl.2015.08.019

subject

Has Abstract

pub_date

2015-09-06 00:00:00

pages

338-47

issn

2213-1582

pii

S2213-1582(15)00157-6

journal_volume

9

pub_type

杂志文章,评审

相关文献

NeuroImage-Clinical文献大全
  • Using concurrent EEG and fMRI to probe the state of the brain in schizophrenia.

    abstract：:Perceptional abnormalities in schizophrenia are associated with hallucinations and delusions, but also with negative symptoms and poor functional outcome. Perception can be studied using EEG-derived event related potentials (ERPs). Because of their excellent temporal resolution, ERPs have been used to ask when percept...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.08.009

    authors： Ford JM,Roach BJ,Palzes VA,Mathalon DH

    更新日期：2016-08-10 00:00:00

  • Prediction of cognitive and motor development in preterm children using exhaustive feature selection and cross-validation of near-term white matter microstructure.

    abstract：Background:Advanced neuroimaging and computational methods offer opportunities for more accurate prognosis. We hypothesized that near-term regional white matter (WM) microstructure, assessed on diffusion tensor imaging (DTI), using exhaustive feature selection with cross-validation would predict neurodevelopment in pre...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.11.023

    authors： Schadl K,Vassar R,Cahill-Rowley K,Yeom KW,Stevenson DK,Rose J

    更新日期：2017-11-29 00:00:00

  • Segregating sustained attention from response inhibition in ADHD: An fMRI study.

    abstract：BACKGROUND:The functional significance of the impairment shown by patients with ADHD on response inhibition tasks is unclear. Dysfunctional behavioral and BOLD responses to rare no-go cues might reflect disruption of response inhibition (mediating withholding the response) or selective attention (identifying the rare c...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101677

    authors： Hwang S,Meffert H,Parsley I,Tyler PM,Erway AK,Botkin ML,Pope K,Blair RJR

    更新日期：2019-01-01 00:00:00

  • Changes in default mode network connectivity in different glucose metabolism status and diabetes duration.

    abstract：AIMS/HYPOTHESES:It is now generally accepted that diabetes increases the risk for cognitive impairment, but the precise mechanisms are poorly understood. In recent years, resting-state functional magnetic resonance imaging (rs-fMRI) is increasingly used to investigate the neural basis of cognitive dysfunction in type 2...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.101629

    authors： Liu H,Liu J,Peng L,Feng Z,Cao L,Liu H,Shen H,Hu D,Zeng LL,Wang W

    更新日期：2019-01-01 00:00:00

  • Disrupted functional connectivity in primary progressive apraxia of speech.

    abstract：:Apraxia of speech is a motor speech disorder thought to result from impaired planning or programming of articulatory movements. It can be the initial or only manifestation of a degenerative disease, termed primary progressive apraxia of speech (PPAOS). The aim of this study was to use task-free functional magnetic res...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.02.036

    authors： Botha H,Utianski RL,Whitwell JL,Duffy JR,Clark HM,Strand EA,Machulda MM,Tosakulwong N,Knopman DS,Petersen RC,Jack CR Jr,Josephs KA,Jones DT

    更新日期：2018-03-03 00:00:00

  • Seizure detection by convolutional neural network-based analysis of scalp electroencephalography plot images.

    abstract：:We hypothesized that expert epileptologists can detect seizures directly by visually analyzing EEG plot images, unlike automated methods that analyze spectro-temporal features or complex, non-stationary features of EEG signals. If so, seizure detection could benefit from convolutional neural networks because their vis...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101684

    authors： Emami A,Kunii N,Matsuo T,Shinozaki T,Kawai K,Takahashi H

    更新日期：2019-01-01 00:00:00

  • Multiparametric brainstem segmentation using a modified multivariate mixture of Gaussians.

    abstract：:The human brainstem is a densely packed, complex but highly organised structure. It not only serves as a conduit for long projecting axons conveying motor and sensory information, but also is the location of multiple primary nuclei that control or modulate a vast array of functions, including homeostasis, consciousnes...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2013.04.017

    authors： Lambert C,Lutti A,Helms G,Frackowiak R,Ashburner J

    更新日期：2013-05-16 00:00:00

  • Structural brain alterations and their association with cognitive function and symptoms in Attention-deficit/Hyperactivity Disorder families.

    abstract：:Gray matter disruptions have been found consistently in Attention-deficit/Hyperactivity Disorder (ADHD). The organization of these alterations into brain structural networks remains largely unexplored. We investigated 508 participants (281 males) with ADHD (N = 210), their unaffected siblings (N = 108), individuals wi...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2020.102273

    authors： Jiang W,Duan K,Rootes-Murdy K,Hoekstra PJ,Hartman CA,Oosterlaan J,Heslenfeld D,Franke B,Buitelaar J,Arias-Vasquez A,Liu J,Turner JA

    更新日期：2020-01-01 00:00:00

  • Intra-individual variability in information processing speed reflects white matter microstructure in multiple sclerosis.

    abstract：:Slowed information processing speed is commonly reported in persons with multiple sclerosis (MS), and is typically investigated using clinical neuropsychological tests, which provide sensitive indices of mean-level information processing speed. However, recent studies have demonstrated that within-person variability o...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2013.06.012

    authors： Mazerolle EL,Wojtowicz MA,Omisade A,Fisk JD

    更新日期：2013-06-28 00:00:00

  • Altered functional brain connectivity in patients with visually induced dizziness.

    abstract：BACKGROUND:Vestibular patients occasionally report aggravation or triggering of their symptoms by visual stimuli, which is called visually induced dizziness (VID). These patients therefore experience dizziness, discomfort, disorientation and postural unsteadiness. The underlying pathophysiology of VID is still poorly u...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.02.020

    authors： Van Ombergen A,Heine L,Jillings S,Roberts RE,Jeurissen B,Van Rompaey V,Mucci V,Vanhecke S,Sijbers J,Vanhevel F,Sunaert S,Bahri MA,Parizel PM,Van de Heyning PH,Laureys S,Wuyts FL

    更新日期：2017-02-28 00:00:00

  • Abnormal brain structure in youth who commit homicide.

    abstract：BACKGROUND:Violence that leads to homicide results in an extreme financial and emotional burden on society. Juveniles who commit homicide are often tried in adult court and typically spend the majority of their lives in prison. Despite the enormous costs associated with homicidal behavior, there have been no serious ne...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2014.05.002

    authors： Cope LM,Ermer E,Gaudet LM,Steele VR,Eckhardt AL,Arbabshirani MR,Caldwell MF,Calhoun VD,Kiehl KA

    更新日期：2014-05-10 00:00:00

  • Distinct neural correlates of trait resilience within core neurocognitive networks in at-risk children and adolescents.

    abstract：Background:Most children who are exposed to threat-related adversity (e.g., violence, abuse, neglect) are resilient - that is, they show stable trajectories of healthy psychological development. Despite this, most research on neurodevelopmental changes following adversity has focused on the neural correlates of negativ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.06.026

    authors： Iadipaolo AS,Marusak HA,Paulisin SM,Sala-Hamrick K,Crespo LM,Elrahal F,Peters C,Brown S,Rabinak CA

    更新日期：2018-06-27 00:00:00

  • Multivariate pattern analysis strategies in detection of remitted major depressive disorder using resting state functional connectivity.

    abstract：:Understanding abnormal resting-state functional connectivity of distributed brain networks may aid in probing and targeting mechanisms involved in major depressive disorder (MDD). To date, few studies have used resting state functional magnetic resonance imaging (rs-fMRI) to attempt to discriminate individuals with MD...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.02.018

    authors： Bhaumik R,Jenkins LM,Gowins JR,Jacobs RH,Barba A,Bhaumik DK,Langenecker SA

    更新日期：2016-03-02 00:00:00

  • MRI and cognitive scores complement each other to accurately predict Alzheimer's dementia 2 to 7 years before clinical onset.

    abstract：BACKGROUND:Predicting cognitive decline and the eventual onset of dementia in patients with Mild Cognitive Impairment (MCI) is of high value for patient management and potential cohort enrichment in pharmaceutical trials. We used cognitive scores and MRI biomarkers from a single baseline visit to predict the onset of d...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.102121

    authors： Zandifar A,Fonov VS,Ducharme S,Belleville S,Collins DL,Alzheimer’s Disease Neuroimaging Initiative.

    更新日期：2020-01-01 00:00:00

  • Association between migraine frequency and neural response to emotional faces: An fMRI study.

    abstract：:Previous studies have demonstrated that migraine is associated with enhanced perception and altered cerebral processing of sensory stimuli. More recently, it has been suggested that this sensory hypersensitivity might reflect a more general enhanced response to aversive emotional stimuli. Using functional magnetic res...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101790

    authors： Szabó E,Galambos A,Kocsel N,Édes AE,Pap D,Zsombók T,Kozák LR,Bagdy G,Kökönyei G,Juhász G

    更新日期：2019-01-01 00:00:00

  • Predicting primary progressive aphasias with support vector machine approaches in structural MRI data.

    abstract：:Primary progressive aphasia (PPA) encompasses the three subtypes nonfluent/agrammatic variant PPA, semantic variant PPA, and the logopenic variant PPA, which are characterized by distinct patterns of language difficulties and regional brain atrophy. To validate the potential of structural magnetic resonance imaging da...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.02.003

    authors： Bisenius S,Mueller K,Diehl-Schmid J,Fassbender K,Grimmer T,Jessen F,Kassubek J,Kornhuber J,Landwehrmeyer B,Ludolph A,Schneider A,Anderl-Straub S,Stuke K,Danek A,Otto M,Schroeter ML,FTLDc study group.

    更新日期：2017-02-06 00:00:00

  • DTI detects water diffusion abnormalities in the thalamus that correlate with an extremity pain episode in a patient with multiple sclerosis.

    abstract：BACKGROUND:Various types of multiple sclerosis (MS) related pain have been discussed. One concept is that deafferentation secondary to lesions in the spino-thalamo-cortical network can cause central pain. However, this hypothesis is somehow limited by a lack of a robust association between pain episodes and sites of le...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2013.01.008

    authors： Deppe M,Müller D,Kugel H,Ruck T,Wiendl H,Meuth SG

    更新日期：2013-01-28 00:00:00

  • White matter integrity in small vessel disease is related to cognition.

    abstract：:Cerebral small vessel disease, including white matter hyperintensities (WMH) and lacunes of presumed vascular origin, is common in elderly people and is related to cognitive impairment and dementia. One possible mechanism could be the disruption of white matter tracts (both within WMH and normal-appearing white matter...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.02.003

    authors： Tuladhar AM,van Norden AG,de Laat KF,Zwiers MP,van Dijk EJ,Norris DG,de Leeuw FE

    更新日期：2015-02-16 00:00:00

  • Role of the default mode resting-state network for cognitive functioning in malignant glioma patients following multimodal treatment.

    abstract：BACKGROUND:Progressive cognitive decline following multimodal neurooncological treatment is a common observation in patients suffering from malignant glioma. Alterations of the default-mode network (DMN) represent a possible source of impaired neurocognitive functioning and were analyzed in these patients. METHODS:Eig...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2020.102287

    authors： Kocher M,Jockwitz C,Caspers S,Schreiber J,Farrher E,Stoffels G,Filss C,Lohmann P,Tscherpel C,Ruge MI,Fink GR,Shah NJ,Galldiks N,Langen KJ

    更新日期：2020-01-01 00:00:00

  • Neural correlates of taste reactivity in autism spectrum disorder.

    abstract：:Selective or 'picky' eating habits are common among those with autism spectrum disorder (ASD). These behaviors are often related to aberrant sensory experience in individuals with ASD, including heightened reactivity to food taste and texture. However, very little is known about the neural mechanisms that underlie tas...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.04.008

    authors： Avery JA,Ingeholm JE,Wohltjen S,Collins M,Riddell CD,Gotts SJ,Kenworthy L,Wallace GL,Simmons WK,Martin A

    更新日期：2018-04-04 00:00:00

  • Hippocampal volume correlates with attenuated negative psychotic symptoms irrespective of antidepressant medication.

    abstract：BACKGROUND:Individuals with at-risk mental state for psychosis (ARMS) often suffer from depressive and anxiety symptoms, which are clinically similar to the negative symptomatology described for psychosis. Thus, many ARMS individuals are already being treated with antidepressant medication. OBJECTIVES:To investigate c...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.04.016

    authors： Bernasconi R,Smieskova R,Schmidt A,Harrisberger F,Raschle NM,Lenz C,Walter A,Simon A,Riecher-Rössler A,Radue EW,Lang UE,Fusar-Poli P,Borgwardt SJ

    更新日期：2015-04-29 00:00:00

  • Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment.

    abstract：:A commonly carried C677T polymorphism in a folate-related gene, MTHFR, is associated with higher plasma homocysteine, a well-known mediator of neuronal damage and brain atrophy. As homocysteine promotes brain atrophy, we set out to discover whether people carrying the C677T MTHFR polymorphism which increases homocyste...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2012.09.012

    authors： Rajagopalan P,Jahanshad N,Stein JL,Hua X,Madsen SK,Kohannim O,Hibar DP,Toga AW,Jack CR Jr,Saykin AJ,Green RC,Weiner MW,Bis JC,Kuller LH,Riverol M,Becker JT,Lopez OL,Thompson PM,Alzheimer's Disease Neuroimaging Initiat

    更新日期：2012-10-04 00:00:00

  • Relation of 18-F-Dopa PET with hypokinesia-rigidity, tremor and freezing in Parkinson's disease.

    abstract：INTRODUCTION:In this retrospective study concerning patients with Parkinson's disease (PD) scanned with 18-F-Dopa PET (N = 129), we looked for an association between reduced 18-F-Dopa uptake and the key PD symptoms tremor and hypokinesia-rigidity. We hypothesized to find a stronger correlation between dopaminergic depl...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.01.010

    authors： Pikstra ARA,van der Hoorn A,Leenders KL,de Jong BM

    更新日期：2016-01-12 00:00:00

  • Using fMRI and machine learning to predict symptom improvement following cognitive behavioural therapy for psychosis.

    abstract：:Cognitive behavioural therapy for psychosis (CBTp) involves helping patients to understand and reframe threatening appraisals of their psychotic experiences to reduce distress and increase functioning. Whilst CBTp is effective for many, it is not effective for all patients and the factors predicting a good outcome rem...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.10.011

    authors： Tolmeijer E,Kumari V,Peters E,Williams SCR,Mason L

    更新日期：2018-01-01 00:00:00

  • Premature white matter aging in patients with right mesial temporal lobe epilepsy: A machine learning approach based on diffusion MRI data.

    abstract：:Brain age prediction based on machine learning has been applied to various neurological diseases to discover its clinical values. By this innovative approach, it has been reported that the patients with refractory epilepsy had premature brain aging. Of refractory epilepsy, right and left subtypes of mesial temporal lo...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.102033

    authors： Chen CL,Shih YC,Liou HH,Hsu YC,Lin FH,Tseng WI

    更新日期：2019-01-01 00:00:00

  • MEG-based detection and localization of perilesional dysfunction in chronic stroke.

    abstract：:Post-stroke impairment is associated not only with structural lesions, but also with dysfunction in surviving perilesional tissue. Previous studies using equivalent current dipole source localization of MEG/EEG signals have demonstrated a preponderance of slow-wave activity localized to perilesional areas. Recent stud...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.03.019

    authors： Chu RK,Braun AR,Meltzer JA

    更新日期：2015-04-08 00:00:00

  • APPswe/PS1dE9 mice with cortical amyloid pathology show a reduced NAA/Cr ratio without apparent brain atrophy: A MRS and MRI study.

    abstract：:Transgenic animal models of Aβ pathology provide mechanistic insight into some aspects of Alzheimer disease (AD) pathology related to Aβ accumulation. Quantitative neuroimaging is a possible aid to improve translation of mechanistic findings in transgenic models to human end phenotypes of brain morphology or function....

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.06.009

    authors： Kuhla A,Rühlmann C,Lindner T,Polei S,Hadlich S,Krause BJ,Vollmar B,Teipel SJ

    更新日期：2017-06-09 00:00:00

  • Phasic amygdala and BNST activation during the anticipation of temporally unpredictable social observation in social anxiety disorder patients.

    abstract：:Anticipation of potentially threatening social situations is a key process in social anxiety disorder (SAD). In other anxiety disorders, recent research of neural correlates of anticipation of temporally unpredictable threat suggests a temporally dissociable involvement of amygdala and bed nucleus of the stria termina...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101735

    authors： Figel B,Brinkmann L,Buff C,Heitmann CY,Hofmann D,Bruchmann M,Becker MPI,Herrmann MJ,Straube T

    更新日期：2019-01-01 00:00:00

  • Hippocampal CA1 subfield predicts episodic memory impairment in Parkinson's disease.

    abstract：OBJECTIVE:Parkinson's disease (PD) episodic memory impairments are common; however, it is not known whether these impairments are due to hippocampal pathology. Hippocampal Lewy-bodies emerge by Braak stage 4, but are not uniformly distributed. For instance, hippocampal CA1 Lewy-body pathology has been specifically asso...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101824

    authors： La C,Linortner P,Bernstein JD,Ua Cruadhlaoich MAI,Fenesy M,Deutsch GK,Rutt BK,Tian L,Wagner AD,Zeineh M,Kerchner GA,Poston KL

    更新日期：2019-01-01 00:00:00

  • Structural connectomics of anxious arousal in early adolescence: Translating clinical and ethological findings.

    abstract：:Etiological explanations of clinical anxiety can be advanced through understanding the neural mechanisms associated with anxiety in youth prior to the emergence of psychopathology. In this vein, the present study sought to investigate how trait anxiety is related to features of the structural connectome in early adole...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.09.012

    authors： Sharp PB,Telzer EH

    更新日期：2017-09-21 00:00:00