Economic and epidemiological impact of early antiretroviral therapy initiation in India.

abstract：:Eastern Europe and Central Asia have the largest drug epidemic globally and the fastest and still expanding HIV epidemic. The Russian Federation and Ukraine together account for over 90% of the reported AIDS cases in the region. If small in absolute numbers, the epidemics are however significant in prevalence rate in ...

journal_title：Journal of the International AIDS Society

authors： Kazatchkine M

更新日期：2014-11-02 00:00:00

abstract：:Family-based interventions with children who are affected by HIV and AIDS are not well established. The Collaborative HIV Prevention and Adolescent Mental Health Program (CHAMP) represents one of the few evidence-based interventions tested in low-income contexts in the US, Caribbean and South Africa. This paper provid...

journal_title：Journal of the International AIDS Society

authors： Bhana A,McKay MM,Mellins C,Petersen I,Bell C

更新日期：2010-06-23 00:00:00

abstract：INTRODUCTION:Two new microbicide products based on topical (vaginal) application of antiretroviral drugs - 1% tenofovir gel and the dapivirine ring - are currently in late-stage clinical testing, and results on their safety and effectiveness are expected to become available in early 2015. WHO guidelines on the use of t...

journal_title：Journal of the International AIDS Society

authors： Lusti-Narasimhan M,Khosla R,Baggaley R,Temmerman M,McGrory E,Farley T

更新日期：2014-09-08 00:00:00

abstract：INTRODUCTION:The majority of new HIV infections occur through mucosal transmission. The availability of readily applicable and accessible platforms for anti-retroviral (ARV) delivery is critical for the prevention of HIV acquisition through sexual transmission in both women and men. There is a compelling need for devel...

journal_title：Journal of the International AIDS Society

authors： Crakes KR,Herrera C,Morgan JL,Olstad K,Hessell AJ,Ziprin P,LiWang PJ,Dandekar S

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:HIV incidence remains high among young women in sub-Saharan Africa in spite of scale-up of HIV testing, behavioural interventions, antiretroviral treatment and medical male circumcision. There is a critical need to critique past approaches and learn about the most effective implementation of evidence-based...

journal_title：Journal of the International AIDS Society

authors： Celum CL,Delany-Moretlwe S,McConnell M,van Rooyen H,Bekker LG,Kurth A,Bukusi E,Desmond C,Morton J,Baeten JM

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:Older adults living with HIV (OALHIV; ≥50 years) who use drugs face unique needs and challenges that compromise their health and wellbeing due to the structural and environmental barriers they experience, in addition to being disproportionately affected by comorbidities. Nevertheless, research on this popu...

journal_title：Journal of the International AIDS Society

authors： Chayama KL,Ng C,McNeil R

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Cardiovascular diseases are increasing in aging HIV-positive patients (HIV+). Impact of traditional cardiovascular risk factors, HIV-specific parameters and antiretroviral therapy (ART) on the incidence of cardiovascular events (CVE) and on the mortality rate are investigated in different HIV+ cohorts. ME...

journal_title：Journal of the International AIDS Society

authors： Esser S,Eisele L,Schwarz B,Schulze C,Holzendorf V,Brockmeyer NH,Hower M,Kwirant F,Rudolph R,Neumann T,Reinsch N

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:The World Health Organization targets for hepatitis C virus (HCV) elimination include a 90% reduction in new infections by 2030. Our objective is to review the modelling evidence and cost data surrounding feasibility of HCV elimination among people living with HIV (PLWH), and identify likely components for...

journal_title：Journal of the International AIDS Society

authors： Martin NK,Boerekamps A,Hill AM,Rijnders BJA

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Since 2003, US government funding to address the HIV and AIDS pandemic has been subject to an anti-prostitution clause. Simultaneously, the efficacy of some HIV prevention efforts for sex work in areas receiving US government funding has diminished. This article seeks to explain why. METHODS:This analysis...

journal_title：Journal of the International AIDS Society

authors： Ditmore MH,Allman D

更新日期：2013-03-28 00:00:00

abstract：BACKGROUND:Psychological factors are often neglected in HIV research, although psychological distress is common in low- to middle-income countries, such as South Africa. There is a need to deepen our understanding of the role of mental health factors in the HIV epidemic. We set out to investigate whether baseline depre...

journal_title：Journal of the International AIDS Society

authors： Nduna M,Jewkes RK,Dunkle KL,Shai NP,Colman I

更新日期：2010-11-15 00:00:00

abstract：INTRODUCTION:The universal test and treat strategy (UTT) was developed to maximize the proportion of all HIV-positive individuals on antiretroviral treatment (ART) and virally suppressed, assuming that it will lead to a reduction in HIV incidence at the population level. The evolution over time of the cross-sectional H...

journal_title：Journal of the International AIDS Society

authors： Larmarange J,Diallo MH,McGrath N,Iwuji C,Plazy M,Thiébaut R,Tanser F,Bärnighausen T,Pillay D,Dabis F,Orne-Gliemann J,ANRS 12249 TasP Study Group.

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:Despite recent advances in the management of HIV infection and increased access to treatment, prevention, care and support, the HIV/AIDS epidemic continues to be a major global health problem, with sub-Saharan Africa suffering by far the greatest humanitarian, demographic and socio-economic burden of the e...

journal_title：Journal of the International AIDS Society

authors： Divaris K,Newman J,Hemingway-Foday J,Akam W,Balimba A,Dusengamungu C,Kalenga L,Mbaya M,Molu BM,Mugisha V,Mukumbi H,Mushingantahe J,Nash D,Niyongabo T,Atibu J,Azinyue I,Kiumbu M,Woelk G

更新日期：2012-11-21 00:00:00

abstract：INTRODUCTION:Antiretroviral (ARV)-based pre-exposure prophylaxis (PrEP) is a promising new HIV prevention strategy. However, variable levels of adherence have yielded mixed results across several PrEP trials and populations. It is not clear how taking ARV - traditionally used for HIV treatment - is perceived and how th...

journal_title：Journal of the International AIDS Society

authors： van der Straten A,Stadler J,Luecke E,Laborde N,Hartmann M,Montgomery ET,VOICE-C Study Team.

更新日期：2014-09-08 00:00:00

abstract：INTRODUCTION:Mortality among HIV-positive adults awaiting antiretroviral therapy (ART) has previously been found to be high. Here, we compare adolescent pre-ART mortality to that of adults in a public sector HIV care programme in Bulawayo, Zimbabwe. METHODS:In this retrospective cohort study, we compared adolescent pr...

journal_title：Journal of the International AIDS Society

authors： Shroufi A,Ndebele W,Nyathi M,Gunguwo H,Dixon M,Saint-Sauveur JF,Taziwa F,Viñoles MC,Ferrand RA

更新日期：2015-02-23 00:00:00

abstract：BACKGROUND:While the number of HIV-positive patients on antiretroviral therapy (ART) in resource-limited settings has increased dramatically, some patients eligible for treatment do not initiate ART even when it is available to them. Understanding why patients opt out of care, or are unable to opt in, is important to a...

journal_title：Journal of the International AIDS Society

authors： Fox MP,Mazimba A,Seidenberg P,Crooks D,Sikateyo B,Rosen S

更新日期：2010-03-06 00:00:00

abstract：INTRODUCTION:Women living with HIV are required to transition into the prevention of mother-to-child transmission of HIV (PMTCT) services when they become pregnant and back to ART services after delivery. Transition can be a vulnerable time when many women are lost from HIV care yet there is little guidance on the opti...

journal_title：Journal of the International AIDS Society

authors： Phillips TK,Teasdale CA,Geller A,Ng'eno B,Mogoba P,Modi S,Abrams EJ

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Treatment as prevention has mobilized new opportunities in preventing HIV transmission and has led to bold new UNAIDS targets in testing, treatment coverage and transmission reduction. These will require not only an increase in investment but also a deeper understanding of the dynamics of combining behavio...

journal_title：Journal of the International AIDS Society

authors： Brown G,Reeders D,Dowsett GW,Ellard J,Carman M,Hendry N,Wallace J

更新日期：2015-12-14 00:00:00

abstract：INTRODUCTION:The clinical value of monitoring CD4 counts in immune reconstituted, virologically suppressed HIV-infected patients is limited. We investigated if absolute lymphocyte counts (ALC) from an automated blood counting machine could accurately estimate CD4 counts. MATERIALS AND METHODS:CD4 counts, ALC and HIV v...

journal_title：Journal of the International AIDS Society

authors： Young B,Lye D,Ng OT,Leo YS

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Within monocyte-derived macrophages, HIV-1 accumulates in intracellular virus-containing compartments (VCCs) that are inaccessible to the external environment, which implicate these cells as latently infected HIV-1 reservoirs. During mother-to-child transmission of HIV-1, human placental macrophages (Hofba...

journal_title：Journal of the International AIDS Society

authors： Johnson EL,Chu H,Byrareddy SN,Spearman P,Chakraborty R

更新日期：2015-01-22 00:00:00

abstract：INTRODUCTION:The evolving HIV epidemic, coupled with advances in HIV treatment, has resulted in an ageing HIV-diagnosed population. It has been suggested that adverse physical and psychological effects of HIV may be higher among older people. However, few studies have examined the effect of older age on well-being for ...

journal_title：Journal of the International AIDS Society

authors： McGowan J,Sherr L,Rodger A,Fisher M,Miners A,Johnson M,Elford J,Collins S,Hart G,Phillips A,Speakman A,Lampe F

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:HIV-1 viral escape in the cerebrospinal fluid (CSF) despite viral suppression in plasma is rare [1,2]. We describe the case of a 50-year-old HIV-1 infected patient who was diagnosed with HIV-1 in 1995. Antiretroviral therapy (ART) was started in 1998 with a CD4 T cell count of 71 cells/ìL and HIV-viremia o...

journal_title：Journal of the International AIDS Society

authors： Béguelin C,Vázquez M,Bertschi M,Yerly S,de Jong D,Rauch A,Cusini A

更新日期：2014-11-02 00:00:00

abstract：:Paediatric antiretroviral treatment (ART) failure is an under-recognized issue that receives inadequate attention in the field of paediatrics and within HIV treatment programmes. With paediatric ART failure rates ranging from 19.3% to over 32% in resource limited settings, a comprehensive evaluation of the causes of f...

journal_title：Journal of the International AIDS Society

authors： Bernheimer JM,Patten G,Makeleni T,Mantangana N,Dumile N,Goemaere E,Cox V

更新日期：2015-07-23 00:00:00

abstract：INTRODUCTION:Engaging at-risk men in HIV prevention programs and services is a current priority, yet there are few effective ways to identify which men are at highest risk or how to best reach them. In this study we generated multi-factor profiles of HIV acquisition/transmission risk for men in Durban, South Africa, to...

journal_title：Journal of the International AIDS Society

authors： Gottert A,Pulerwitz J,Heck CJ,Cawood C,Mathur S

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:HIV diagnoses among gay and bisexual men have increased over the past decade in Australia. HIV point-of-care testing (POCT) was introduced in Australia in 2011 as a strategy to increase HIV testing by making the testing process more convenient. We surveyed gay and bisexual men undergoing POCT to assess bar...

journal_title：Journal of the International AIDS Society

authors： Conway DP,Holt M,Couldwell DL,Smith DE,Davies SC,McNulty A,Keen P,Cunningham P,Guy R,Sydney Rapid HIV Test Study.

更新日期：2015-08-27 00:00:00

abstract：BACKGROUND:Social constructions of masculinity have been shown to serve as an obstacle to men's access and adherence to antiretroviral therapies (ART). In the light of women's relative lack of power in many aspects of interpersonal relationships with men in many African settings, our objective is to explore how male de...

journal_title：Journal of the International AIDS Society

authors： Skovdal M,Campbell C,Nyamukapa C,Gregson S

更新日期：2011-06-09 00:00:00

abstract：INTRODUCTION:HIV-1-associated CD4+ T-cell depletion is a consequence of uninfected cell death. Nef is one of the viral factors that trigger apoptosis on bystander cells, though the plasma Nef levels do not correlate with Th lymphocytes counts. The aim of our study was to evaluate whether anti-Nef antibodies were involv...

journal_title：Journal of the International AIDS Society

authors： Corró G,Crudeli CM,Rocco CA,Marino SA,Sen L

更新日期：2014-02-14 00:00:00

abstract：INTRODUCTION:This was a descriptive non-interventional study in HIV-1-infected patients treated with DRV/r conducted in the clinical setting, with a single-arm prospective design. The primary objective was to collect data on utilization of darunavir/ritonavir (DRV/r) under the conditions described in the marketing auth...

journal_title：Journal of the International AIDS Society

authors： Antinori A,Galli M,Gianotti N,Mussini C,Quirino T,Sterrantino K,Mancusi D,Termini R

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Infection with HIV subtype A has been associated with poorer neurocognitive outcomes compared to HIV subtype D in Ugandan children not eligible for antiretroviral therapy (ART). In this study, we sought to determine whether subtype-specific differences are also observed among children receiving ART. MATER...

journal_title：Journal of the International AIDS Society

authors： Bangirana P,Ruel TD,Boivin MJ,Pillai SK,Giron LB,Sikorskii A,Banik A,Achan J

更新日期：2017-10-01 00:00:00

abstract：INTRODUCTION:Gonorrhoea and chlamydia cases have been rising among gay, bisexual and other men who have sex with men (MSM) over the last decade. The majority of cases are extragenital and occur at the oropharynx and anorectum. The aim of this narrative review was to review the risk factors and mode of transmission for ...

journal_title：Journal of the International AIDS Society

authors： Chow EP,Fairley CK

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Despite significant gains in access to early infant diagnosis (EID) over the past decade, most HIV-exposed infants still do not get tested for HIV in the first two months of life. For those who are tested, the long turnaround time between when the sample is drawn and when the results are returned leads to ...

journal_title：Journal of the International AIDS Society

authors： Essajee S,Vojnov L,Penazzato M,Jani I,Siberry GK,Fiscus SA,Markby J

更新日期：2015-12-02 00:00:00