WHO guidance grounded in a comprehensive approach to sexual and reproductive health and human rights: topical pre-exposure prophylaxis.

abstract：INTRODUCTION:Viral load testing is essential to manage HIV disease, especially in infants and children. Early infant diagnosis is performed using nucleic-acid testing in children under 18 months. Resource-limited health systems face severe challenges to scale-up both viral load and early infant diagnosis to unprecedent...

journal_title：Journal of the International AIDS Society

authors： Vubil A,Nhachigule C,Loquiha O,Meggi B,Mabunda N,Bollinger T,Sacks JA,Jani I,Vojnov L

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:While there is a global consensus on monitoring Human Immunodeficiency Virus (HIV) treatment progress, there has been less attention to the degree of consistency of the measurement of HIV prevention programmes-and the global prevention response is not on-track to achieve 2020 goals. In this paper, we asses...

journal_title：Journal of the International AIDS Society

authors： Sekimitsu S,DePasse J,Morrison M,Mahy M,Rice B,Earle K,Daley K,Larson J,Carter A,Garnett GP,Holmes CB

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:To be used most effectively, pre-exposure prophylaxis (PrEP) should be prioritized to those at high risk of acquisition and would ideally be aligned with time periods of increased exposure. Identifying such time periods is not always straightforward, however. Gaza Province in southern Mozambique is charact...

journal_title：Journal of the International AIDS Society

authors： Cremin I,Morales F,Jewell BL,O'Reilly KR,Hallett TB

更新日期：2015-07-20 00:00:00

abstract：INTRODUCTION:HIV infection impairs maintenance of immunological memory, yet few studies of HIV-positive adults receiving 7-valent pneumococcal conjugate vaccine (PCV7) have followed them beyond the first year. We determined and compared the durability of serological responses and the clinical outcomes of HIV-positive a...

journal_title：Journal of the International AIDS Society

authors： Cheng A,Chang SY,Tsai MS,Su YC,Liu WC,Sun HY,Hung CC

更新日期：2016-01-29 00:00:00

abstract：BACKGROUND:Young people in southern and eastern Africa remain disproportionately vulnerable to HIV with gender inequalities and livelihood insecurities being key drivers of this. Behavioural HIV prevention interventions have had weak outcomes and a new generation of structural interventions have emerged seeking to chal...

journal_title：Journal of the International AIDS Society

authors： Gibbs A,Willan S,Misselhorn A,Mangoma J

更新日期：2012-06-14 00:00:00

abstract：INTRODUCTION:Policies for rationing antiretroviral therapy (ART) have been subject to on-going ethical debates. Introduced in Malawi in 2011, Option B+ prioritized HIV-positive pregnant women for lifelong ART regardless of the underlying state of their immune system, shifting the logic of allocation away from medical e...

journal_title：Journal of the International AIDS Society

authors： Yeatman S,Trinitapoli J

更新日期：2017-03-08 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) on antiretroviral therapy (ART) experience high rates of non-communicable diseases (NCDs). These co-morbidities often accumulate and older adults may suffer from multimorbidity. Multimorbidity has been associated with loss of quality of life, polypharmacy, and increased risk ...

journal_title：Journal of the International AIDS Society

authors： Castilho JL,Escuder MM,Veloso V,Gomes JO,Jayathilake K,Ribeiro S,Souza RA,Ikeda ML,de Alencastro PR,Tupinanbas U,Brites C,McGowan CC,Grangeiro A,Grinsztejn B

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Outbreaks of hepatitis C virus (HCV) infections among HIV-positive men who have sex with men (MSM) have been observed globally. Using a multi-modelling approach we estimate the time and number of direct-acting antiviral treatment courses required to achieve an 80% reduction in HCV prevalence among HIV-posi...

journal_title：Journal of the International AIDS Society

authors： Scott N,Stoové M,Wilson DP,Keiser O,El-Hayek C,Doyle J,Hellard M

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Clinicians often do not have the time and possibilities to read all scientific evidence necessary to maintain high quality patient care. They rely on guidelines made by experts to help them in their daily work. METHODS:We compared the 2012 recommendations and the arguments of the IAS-USA Panel with the da...

journal_title：Journal of the International AIDS Society

authors： Piso RJ

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Evidence suggests that people who inject drugs often begin their drug use and injecting practices in adolescence, yet there are limited data available on the HIV epidemic and the responses for this population. The comprehensive package of interventions for the prevention, treatment and care of HIV infectio...

journal_title：Journal of the International AIDS Society

authors： Krug A,Hildebrand M,Sun N

更新日期：2015-02-26 00:00:00

abstract：INTRODUCTION:In response to the increasing burden of HIV, the Ugandan government has employed different service delivery models since 2004 that aim to reduce costs and remove barriers to accessing HIV care. These models include community-based approaches to delivering antiretroviral therapy (ART) and delegating tasks t...

journal_title：Journal of the International AIDS Society

authors： Vu L,Waliggo S,Zieman B,Jani N,Buzaalirwa L,Okoboi S,Okal J,Borse NN,Kalibala S

更新日期：2016-07-20 00:00:00

abstract：INTRODUCTION:Transactional sex is a structural driver of HIV for women and girls in sub-Saharan Africa. In transactional relationships, sexual and economic obligations intertwine and may have positive and negative effects on women's financial standing and social status. We conducted a clinic-based survey with pregnant ...

journal_title：Journal of the International AIDS Society

authors： Fielding-Miller R,Dunkle KL,Hadley C,Cooper HL,Windle M

更新日期：2017-07-18 00:00:00

abstract：INTRODUCTION:The clinical value of monitoring CD4 counts in immune reconstituted, virologically suppressed HIV-infected patients is limited. We investigated if absolute lymphocyte counts (ALC) from an automated blood counting machine could accurately estimate CD4 counts. MATERIALS AND METHODS:CD4 counts, ALC and HIV v...

journal_title：Journal of the International AIDS Society

authors： Young B,Lye D,Ng OT,Leo YS

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:WHO recommends assisted partner notification (APN) for people living with HIV (PLHIV). These services have not been widely scaled in Central Asia. We describe the results from an APN intervention implemented within a programme focused on PLHIV and people who inject drugs in Kazakhstan, the Kyrgyz Republic ...

journal_title：Journal of the International AIDS Society

authors： Little KM,Kan M,Samoylova O,Rsaldinova A,Saliev D,Ishokov F,Gray R,Hasen NS

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:Rilpivirine (RPV) is a new once-daily, non-nucleoside, reverse transcriptase inhibitor (NNRTI). In treatment-naïve patients, RPV has shown non-inferior antiviral activity to efavirenz but data in treatment-experienced patients are more limited. We assessed the efficacy and safety of RPV in treatment-experi...

journal_title：Journal of the International AIDS Society

authors： Gazaignes S,Resche-Rigon M,Yang C,Gatey C,Munier AL,Desseaux K,Rozenbaum W,Molina JM

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:The majority of new HIV infections occur through mucosal transmission. The availability of readily applicable and accessible platforms for anti-retroviral (ARV) delivery is critical for the prevention of HIV acquisition through sexual transmission in both women and men. There is a compelling need for devel...

journal_title：Journal of the International AIDS Society

authors： Crakes KR,Herrera C,Morgan JL,Olstad K,Hessell AJ,Ziprin P,LiWang PJ,Dandekar S

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:The long-term effects of an intensified induction regimen are unknown. In this pilot, randomized, prospective study we evaluate the effect of a short-term four-drugs induction regimen in patients with high baseline viral load. METHODS:Naive patients with HIV-RNA>100.000 copies/ml receiving TDF+FTC+EFV+RAL...

journal_title：Journal of the International AIDS Society

authors： Maggiolo F,Masini G,Astuti N,Di Filippo E,Benatti S,Valenti D,Callegaro AP,Rizzi M

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Switching to a rilpivirine, tenofovir and emtricitabine (RTE) single-tablet regimen (STR) has been evaluated in a limited number of virologically suppressed patients. The aim of this study was to describe clinical outcomes in HIV-positive patients switched from a suppressive antiretroviral regimen to RTE S...

journal_title：Journal of the International AIDS Society

authors： Gianotti N,Poli A,Nozza S,Spagnuolo V,Tambussi G,Bossolasco S,Cinque P,Maillard M,Cernuschi M,Galli L,Lazzarin A,Castagna A

更新日期：2015-07-30 00:00:00

abstract：INTRODUCTION:Mortality among HIV-positive adults awaiting antiretroviral therapy (ART) has previously been found to be high. Here, we compare adolescent pre-ART mortality to that of adults in a public sector HIV care programme in Bulawayo, Zimbabwe. METHODS:In this retrospective cohort study, we compared adolescent pr...

journal_title：Journal of the International AIDS Society

authors： Shroufi A,Ndebele W,Nyathi M,Gunguwo H,Dixon M,Saint-Sauveur JF,Taziwa F,Viñoles MC,Ferrand RA

更新日期：2015-02-23 00:00:00

abstract：INTRODUCTION:Cenicriviroc (CVC), a once-daily, dual CCR5/CCR2 co-receptor antagonist, has completed Phase 2b development. CVC demonstrated favourable safety and similar efficacy compared with efavirenz (EFV) in Study 202 (NCT01338883); an ex vivo sub-analysis evaluated treatment effects on HIV entry, measured by intrac...

journal_title：Journal of the International AIDS Society

authors： Kramer V,Hassounah S,Colby-Germinario S,Mesplède T,Lefebvre E,Wainberg M

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:Recent debates on how to achieve an optimal HIV response are dominated by intervention strategies that fail to recognize children's role in the community response to HIV. Whilst formal responses are key to the HIV response, they must recognize and build on indigenous community resources. This study examine...

journal_title：Journal of the International AIDS Society

authors： Skovdal M,Magutshwa-Zitha S,Campbell C,Nyamukapa C,Gregson S

更新日期：2013-02-04 00:00:00

abstract：INTRODUCTION:Preventive therapy is essential for reducing tuberculosis (TB) burden among people living with HIV (PLWH) in high-burden settings. Short-course preventive therapy regimens, such as three-month weekly rifapentine and isoniazid (3HP) and one-month daily rifapentine and isoniazid (1HP), may help facilitate up...

journal_title：Journal of the International AIDS Society

authors： Ferguson O,Jo Y,Pennington J,Johnson K,Chaisson RE,Churchyard G,Dowdy D

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:For many women living with HIV (WLWH), the disclosure of positive status can lead to either an extension of former violence or new conflict specifically associated with HIV status disclosure. This study aims to explore the following about WLWH: 1. the women's experiences of intimate partner violence (IPV) ...

journal_title：Journal of the International AIDS Society

authors： Colombini M,James C,Ndwiga C,Integra team.,Mayhew SH

更新日期：2016-03-31 00:00:00

abstract：INTRODUCTION:Lipodystrophy is still a matter of concern in HIV+ patients receiving ART. However, long-term fat change in patients taking non-thymidine regimens is not well known. MATERIALS AND METHODS:A prospective ongoing fat change assessment including clinical evaluation and dexa scans (Hologic QDR 4500) is being c...

journal_title：Journal of the International AIDS Society

authors： Ferrer E,Navarro A,Curto J,Medina P,Rozas N,Barrera G,Saumoy M,Tiraboschi JM,Gomez C,Podzamczer D

更新日期：2014-11-02 00:00:00

abstract：INTRODUCTION:HIV incidence among men who have sex with men (MSM) is high in China. Pre-exposure prophylaxis (PrEP) is a promising mean to prevent HIV transmission but it is not widely available in China. We conducted a large Internet-based online survey to assess the willingness of Chinese MSM to take PrEP and associat...

journal_title：Journal of the International AIDS Society

authors： Han J,Bouey JZ,Wang L,Mi G,Chen Z,He Y,Viviani T,Zhang F

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:HIV self-testing (HIVST) offers an alternative to facility-based HIV testing services, particularly for populations such as men who have sex with men (MSM) who may fear accessing testing due to stigma, discrimination and criminalization. Innovative HIV testing approaches are needed to meet the goal of 90% ...

journal_title：Journal of the International AIDS Society

authors： Tun W,Vu L,Dirisu O,Sekoni A,Shoyemi E,Njab J,Ogunsola S,Adebajo S

更新日期：2018-07-01 00:00:00

abstract：:Improved knowledge, better programmes and policies, effective treatment and other scientific developments have reduced levels of new HIV infections globally. Evidence shows that programmes that prevent HIV among sex workers and their clients are most successful when all aspects of vulnerability are addressed and when ...

journal_title：Journal of the International AIDS Society

authors： Overs C,Loff B

更新日期：2013-08-29 00:00:00

abstract：INTRODUCTION:The World Health Organization targets for hepatitis C virus (HCV) elimination include a 90% reduction in new infections by 2030. Our objective is to review the modelling evidence and cost data surrounding feasibility of HCV elimination among people living with HIV (PLWH), and identify likely components for...

journal_title：Journal of the International AIDS Society

authors： Martin NK,Boerekamps A,Hill AM,Rijnders BJA

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Global guidelines emphasize the ethical obligation of investigators to help participants in HIV-endpoint trials reduce HIV risk by offering an optimal HIV prevention package. Oral pre-exposure prophylaxis (PrEP) has increasingly become part of state-of-the-art HIV prevention. Here we describe the process o...

journal_title：Journal of the International AIDS Society

authors： Beesham I,Welch JD,Heffron R,Pleaner M,Kidoguchi L,Palanee-Phillips T,Ahmed K,Baron D,Bukusi EA,Louw C,Mastro TD,Smit J,Batting JR,Malahleha M,Bailey VC,Beksinska M,Donnell D,Baeten JM,ECHO Trial Consortium.

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to determine the prevalence of neurocognitive impairment among HIV-positive individuals in Botswana, using the International HIV Dementia Scale (IHDS). We also compared performance on the IHDS with performance on tests of verbal learning/memory and processing speed, an...

journal_title：Journal of the International AIDS Society

authors： Lawler K,Mosepele M,Ratcliffe S,Seloilwe E,Steele K,Nthobatsang R,Steenhoff A

更新日期：2010-04-20 00:00:00