Cost-effectiveness of Interferon-free therapy for Hepatitis C in Germany--an application of the efficiency frontier approach.

abstract：BACKGROUND:The current low access to virological testing to confirm chronic viraemic HCV infection in low- and middle-income countries (LMIC) is limiting the rollout of hepatitis C (HCV) care. Existing tests are complex, costly and require sophisticated laboratory infrastructure. Diagnostic manufacturers need guidance ...

journal_title：BMC infectious diseases

authors： Ivanova Reipold E,Easterbrook P,Trianni A,Panneer N,Krakower D,Ongarello S,Roberts T,Miller V,Denkinger C

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Following infection with Mycobacterium tuberculosis (M.tb), individuals may rapidly develop tuberculosis (TB) disease or enter a "latent" infection state with a low risk of progression to disease. Mathematical models use a variety of structures and parameterisations to represent this process. The effect of t...

journal_title：BMC infectious diseases

authors： Sumner T,White RG

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:The mobility of female sex workers (FSWs) is a factor in the geographic spread of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). This study describes FSW mobility patterns in a high risk area of China to identify factors associated with increased mobility, and to study t...

journal_title：BMC infectious diseases

authors： Wang H,Chen RY,Sharp GB,Brown K,Smith K,Ding G,Jin X,Xu J,Dong R,Wang N

更新日期：2010-07-09 00:00:00

abstract：BACKGROUND:Pregnant women in malaria endemic areas are at high risk of P. falciparum infection and its complications. This study investigated the prevalence and risk factors for P. falciparum infection and malaria among pregnant women reporting for first antenatal care (ANC) clinic visit in the mount Cameroon area. ME...

journal_title：BMC infectious diseases

authors： Anchang-Kimbi JK,Nkweti VN,Ntonifor HN,Apinjoh TO,Tata RB,Chi HF,Achidi EA

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:Osteomyelitis is a difficult-to-cure infection with a high relapse rate despite combined medical and surgical therapies. Some severity factors, duration of antimicrobial therapy and type of surgical procedure might influence osteomyelitis relapse. METHODS:116 patients with osteomyelitis were followed for ≥1...

journal_title：BMC infectious diseases

authors： Garcia Del Pozo E,Collazos J,Carton JA,Camporro D,Asensi V

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:In vitro data suggests that suboptimal initial vancomycin exposure may select for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) infections. However, no clinical studies have evaluated the relationship between initial vancomycin exposure and emergence of hVISA. This pilot study seeks to ...

journal_title：BMC infectious diseases

authors： Martirosov DM,Bidell MR,Pai MP,Scheetz MH,Rosenkranz SL,Faragon C,Malik M,Mendes RE,Jones RN,McNutt LA,Lodise TP

更新日期：2017-08-02 00:00:00

abstract：BACKGROUND:To better understand potential transmission risks from contact with the body fluids of children, we monitored the presence and amount of CMV shedding over time in healthy CMV-seropositive children. METHODS:Through screening we identified 36 children from the Atlanta, Georgia area who were CMV-seropositive, ...

journal_title：BMC infectious diseases

authors： Cannon MJ,Stowell JD,Clark R,Dollard PR,Johnson D,Mask K,Stover C,Wu K,Amin M,Hendley W,Guo J,Schmid DS,Dollard SC

更新日期：2014-11-13 00:00:00

abstract：BACKGROUND:The risk factors, microbial etiology, differentiation, and clinical features of purulent and non-purulent cellulitis are not well defined in Taiwan. METHODS:We conducted a retrospective cohort study of hospitalized adults with cellulitis in Taiwan in 2013. The demographic characteristics, underlying disease...

journal_title：BMC infectious diseases

authors： Lee CY,Tsai HC,Kunin CM,Lee SS,Chen YS

更新日期：2015-08-05 00:00:00

abstract：BACKGROUND:Nitric oxide (NO*) plays a pivotal role as a leishmanicidal agent in mouse macrophages. NO* resistant Escherichia coli and Mycobacterium tuberculosis have been associated with a severe outcome of these diseases. METHODS:In this study we evaluated the in vitro toxicity of nitric oxide for the promastigote st...

journal_title：BMC infectious diseases

authors： Giudice A,Camada I,Leopoldo PT,Pereira JM,Riley LW,Wilson ME,Ho JL,de Jesus AR,Carvalho EM,Almeida RP

更新日期：2007-02-22 00:00:00

abstract：BACKGROUND:Group B Streptococcus (GBS) serotype (Ia, Ib, II-IX) correlates with pathogen virulence and clinical prognosis. Epidemiological studies of seroprevalence are an important metric for determining the proportion of serotypes in a given population. The purpose of this study was to evaluate the prevalence of indi...

journal_title：BMC infectious diseases

authors： Ippolito DL,James WA,Tinnemore D,Huang RR,Dehart MJ,Williams J,Wingerd MA,Demons ST

更新日期：2010-11-24 00:00:00

abstract：BACKGROUND:Due to limited therapeutic options, the spread of extended-spectrum beta-lactamases (ESBLs) have become a major public health concern. We conducted a prospective, randomized, open-label comparison of the therapeutic efficacy of piperacillin-tazobactam (PTZ), cefepime, and ertapenem in febrile nosocomial urin...

journal_title：BMC infectious diseases

authors： Seo YB,Lee J,Kim YK,Lee SS,Lee JA,Kim HY,Uh Y,Kim HS,Song W

更新日期：2017-06-07 00:00:00

abstract：BACKGROUND:Drug susceptibility testing (DST) remains an important concern for implementing treatment of MDR tuberculosis patients. Implementation of molecular tests for drug resistance identification would facilitate DST particularly in developing countries where culturing is difficult to perform. We have characterized...

journal_title：BMC infectious diseases

authors： Surcouf C,Heng S,Pierre-Audigier C,Cadet-Daniel V,Namouchi A,Murray A,Gicquel B,Guillard B

更新日期：2011-09-28 00:00:00

abstract：BACKGROUND:Molecular strain typing of tuberculosis isolates has led to increased understanding of the epidemiological characteristics of the disease and improvements in its control, diagnosis and treatment. However, molecular cluster investigations, which aim to detect previously unidentified cases, remain challenging....

journal_title：BMC infectious diseases

authors： Smith CM,Hayward AC

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:Following delivery by caesarean section, surgical site infection is the most common infectious complication. Despite a large number of caesarean sections performed at Debre Markos Referral Hospital, there was no study documenting the incidence of surgical site infection after caesarean section. Therefore, th...

journal_title：BMC infectious diseases

authors： Ketema DB,Wagnew F,Assemie MA,Ferede A,Alamneh AA,Leshargie CT,Kibret GD,Petrucka P,Telayneh AT,Alebel A

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:Plasma proteins are known to interfere the drug metabolism during therapy. As limited information is available regarding the role of plasma proteins in HIV drug resistance during ART in HIV/AIDS patients, the present study aimed to identify and characterize the differentially expressed plasma proteins in the...

journal_title：BMC infectious diseases

authors： Barik SK,Mohanty KK,Mohanty AK,Rawat P,Gopal G,Bisht D,Patil SA,Singh R,Sharma D,Tripathy SP,Tandon R,Singh TP,Jena S

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:After the onset of HAART, some HIV-infected individuals under treatment present a exacerbated inflammation in response to a latent or a previously treated opportunistic pathogen termed immune reconstitution inflammatory syndrome (IRIS). Few reports of tegumentary leishmaniasis have been described in associat...

journal_title：BMC infectious diseases

authors： Gois L,Badaró R,Schooley R,Grassi MF

更新日期：2015-02-03 00:00:00

abstract：BACKGROUND:Klebsiella pneumoniae bloodstream infections (BSIs) occur with significant prevalence and high mortality worldwide. Antimicrobial resistance and virulence are two main factors participating in the pathogenicity of K. pneumoniae. Here we investigated the prevalence of blaKPC and virulence factors in K. pneumo...

journal_title：BMC infectious diseases

authors： Xu M,Fu Y,Kong H,Chen X,Chen Y,Li L,Yang Q

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:There is conclusive evidence that human papillomavirus (HPV) infections of the cervix are a necessary cause of cervical cancer. In Italy there are consistent data of HPV prevalence in women aged 25 - 64 years, but there is limited data for younger women. The objective of this on-going 3-year prospective coho...

journal_title：BMC infectious diseases

authors： Confortini M,Carozzi F,Zappa M,Ventura L,Iossa A,Cariaggi P,Brandigi L,Franchini M,Mirri F,Viacava P,Scarfantoni A,Bazzanti D,Sani C

更新日期：2010-06-07 00:00:00

abstract：BACKGROUND:Under-reporting of tuberculosis (TB) cases complicates disease control, hinders contact tracing and alters the accuracy of epidemiological data, including disease burden. The objective of the present study is to evaluate the proportion of unreported TB cases in Spanish healthcare facilities and to identify t...

journal_title：BMC infectious diseases

authors： Morales-García C,Rodrigo T,García-Clemente MM,Muñoz A,Bermúdez P,Casas F,Somoza M,Milá C,Penas A,Hidalgo C,Casals M,Caylá JA,Working Group on Under-reporting of Tuberculosis in Spain.

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:The management of disseminated cysticercosis is unclear and largely considered hazardous. The role of albendazole remains controversial in such patients. METHODS:A tertiary care, University hospital-based prospective intervention study was conducted from December 2015 to December 2017. Patients with dissemi...

journal_title：BMC infectious diseases

authors： Pandey S,Malhotra HS,Garg RK,Malhotra KP,Kumar N,Rizvi I,Jain A,Kohli N,Verma R,Sharma P,Uniyal R,Pandey S

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:The epidemic patterns of influenza B infection and their association with climate conditions are not well understood. Influenza surveillance in Okinawa is important for clarifying transmission patterns in both temperate and tropical regions. Using surveillance data, collected over 7 years in the subtropical ...

journal_title：BMC infectious diseases

authors： Iha Y,Kinjo T,Parrott G,Higa F,Mori H,Fujita J

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:Recent analysis of trends of non-invasive infections with methicillin resistant Staphylococcus aureus (MRSA), of trends of MRSA infections in outpatient settings and of co-resistance profiles of MRSA isolates are scarce or lacking in Germany. METHODS:We analysed data from the Antimicrobial Resistance Survei...

journal_title：BMC infectious diseases

authors： Walter J,Noll I,Feig M,Weiss B,Claus H,Werner G,Eckmanns T,Hermes J,Abu Sin M

更新日期：2017-02-23 00:00:00

abstract：BACKGROUND:Due to a lack of survey of health care seeking behavior for influenza, the actual magnitude of influenza in Beijing of China has not been well described. METHODS:During 2013-2014 influenza season, two cross-sectional household surveys were carried out respectively during the epidemic and non-epidemic season...

journal_title：BMC infectious diseases

authors： Wang X,Wu S,Yang P,Li H,Chu Y,Tang Y,Hua W,Zhang H,Li C,Wang Q

更新日期：2017-02-03 00:00:00

abstract：BACKGROUND:Lemierre's syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction. CASE PRESENTATION:A 17-year old female, with no previous medical hist...

journal_title：BMC infectious diseases

authors： Constantin JM,Mira JP,Guerin R,Cayot-Constantin S,Lesens O,Gourdon F,Romaszko JP,Linval P,Laurichesse H,Bazin JE

更新日期：2006-07-17 00:00:00

abstract：BACKGROUND:Kazakhstan remains a high-burden TB prevalence country with a concomitent high-burden of multi-drug resistant tuberculosis. For this reason, we performed an in depth genetic diversity and population structure characterization of Mycobacterium tuberculosis complex (MTC) genetic diversity in Kazakhstan with bo...

journal_title：BMC infectious diseases

authors： Klotoe BJ,Kacimi S,Costa-Conceicão E,Gomes HM,Barcellos RB,Panaiotov S,Haj Slimene D,Sikhayeva N,Sengstake S,Schuitema AR,Akhalaia M,Alenova A,Zholdybayeva E,Tarlykov P,Anthony R,Refrégier G,Sola C

更新日期：2019-06-24 00:00:00

abstract：BACKGROUND:Antiretroviral therapy dramatically reduced HIV-related morbidity and mortality, prolonging the lifespan of HIV-infected patients. Greater duration of infection and exposure to antiretroviral therapy makes these patients susceptible to traditional cardio-metabolic risk factors and pathologies. The optimal di...

journal_title：BMC infectious diseases

authors： Coelho AR,Moreira FA,Santos AC,Silva-Pinto A,Sarmento A,Carvalho D,Freitas P

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:Haemorrhagic fever with renal syndrome (HFRS) is a natural epidemic disease caused by various types of viruses of the genus Hantavirus, which are mainly transmitted by contact with the infected rodents and their droppings. Pregnancy complicated with HFRS is rare; however, adverse maternal and foetal outcomes...

journal_title：BMC infectious diseases

authors： Ying X,Lai X,Jin X,Cai L,Li X

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:The pathogenic potential and commensal nature of Staphylococcus aureus allows for easy transmission both within and outside of the hospital environment, and nasal carriage may be responsible for some serious infections. This study aimed to determine the molecular and epidemiological characteristics of nasal ...

journal_title：BMC infectious diseases

authors： Chen B,Dai X,He B,Pan K,Li H,Liu X,Bao Y,Lao W,Wu X,Yao Y,Huang S

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:Evidence has existed for decades that higher doses of rifampin may be more effective, but potentially more toxic, than standard doses used in tuberculosis treatment. Whether increased doses of rifampin could safely shorten treatment remains an open question. METHODS/DESIGN:The HIRIF study is a phase II rand...

journal_title：BMC infectious diseases

authors： Milstein M,Lecca L,Peloquin C,Mitchison D,Seung K,Pagano M,Coleman D,Osso E,Coit J,Vargas Vasquez DE,Sanchez Garavito E,Calderon R,Contreras C,Davies G,Mitnick CD

更新日期：2016-08-27 00:00:00

abstract：BACKGROUND:Hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a serious public health problem in China. The National Notifiable Disease Surveillance System (NNDSS) was established online by China CDC in 2004 and rodent surveillance sites were adjusted to 40 sites in 22 provinces in 2005. Here we ana...

journal_title：BMC infectious diseases

authors： Zhang S,Wang S,Yin W,Liang M,Li J,Zhang Q,Feng Z,Li D

更新日期：2014-07-11 00:00:00