当前位置： SCI文献检索 > BMJ Open期刊下所有文献 > Retention in care prior to antiretroviral treatment eligibility in sub-Saharan Africa: a systematic review of the literature.

Retention in care prior to antiretroviral treatment eligibility in sub-Saharan Africa: a systematic review of the literature.

Abstract：

OBJECTIVE:We aimed at summarising rates and factors associated with retention in HIV care prior to antiretroviral treatment (ART) eligibility in sub-Saharan Africa. DESIGN:We conducted a systematic literature review (2002-2014). We searched Medline/Pubmed, Scopus and Web of Science, as well as proceedings of conferences. We included all original research studies published in peer-reviewed journals, which used quantitative indicators of retention in care prior to ART eligibility. PARTICIPANTS:People not yet eligible for ART. PRIMARY AND SECONDARY OUTCOMES:Rate of retention in HIV care prior to ART eligibility and associated factors. RESULTS:10 papers and 2 abstracts were included. Most studies were conducted in Southern and Eastern Africa between 2004 and 2011 and reported retention rates in pre-ART care up to the second CD4 measurement. Definition of retention in HIV care prior to ART eligibility differed substantially across studies. Retention rates ranged between 23% and 88% based on series ranging from 112 to 10,314 individuals; retention was higher in women, individuals aged >25 years, those with low CD4 count, high body mass index or co-infected with tuberculosis, and in settings with free cotrimoxazole use. CONCLUSIONS:Retention in HIV care prior to ART eligibility in sub-Saharan Africa has been insufficiently described so far leaving major research gaps, especially regarding long-term retention rates and sociodemographic, economic, clinical and programmatic logistic determinants. The prospective follow-up of newly diagnosed individuals is required to better evaluate attrition prior to ART eligibility among HIV-infected people.

journal_name

BMJ Open

journal_title

BMJ open

authors

Plazy M,Orne-Gliemann J,Dabis F,Dray-Spira R

doi

10.1136/bmjopen-2014-006927

subject

Has Abstract

pub_date

2015-06-24 00:00:00

pages

e006927

issue

6

issn

2044-6055

pii

bmjopen-2014-006927

journal_volume

5

pub_type

杂志文章,评审

相关文献

BMJ Open文献大全