Safety of the concurrent treatment of dogs with Bravecto (fluralaner) and Scalibor protectorband (deltamethrin).

Abstract:

BACKGROUND:Bravecto (fluralaner; MSD Animal Health) is a novel systemic ectoparasiticide for dogs providing long-acting flea- and tick-control after a single oral dose. Scalibor Protectorband (deltamethrin; MSD Animal Health) is a collar often used to reduce sandfly feeding for leishmaniasis prevention. This study investigated the safety of the concurrent use of Bravecto and Scalibor Protectorband at the recommended dosage regimens. FINDINGS:Throughout the study period of 24 weeks, there were no clinical findings related to the concurrent treatment with Bravecto in dogs fitted with Scalibor Protectorband at the recommended dosage regimen. CONCLUSIONS:Concurrent treatment with Bravecto in dogs fitted with Scalibor Protectorband is well tolerated.

journal_name

Parasit Vectors

journal_title

Parasites & vectors

authors

Walther FM,Fisara P,Allan MJ,Roepke RK,Nuernberger MC

doi

10.1186/1756-3305-7-105

subject

Has Abstract

pub_date

2014-03-19 00:00:00

pages

105

issn

1756-3305

pii

1756-3305-7-105

journal_volume

7

pub_type

杂志文章
  • Transmission of the eyeworm Thelazia callipaeda: between fantasy and reality.

    abstract:BACKGROUND:Thelazia callipaeda is transmitted by Phortica variegata, a drosophilid that feeds on lachrymal secretions of mammals. Scientific information on human thelaziosis is still relatively limited, mainly for physicians and ophthalmologists. Indeed, the literature is full of misleading information on the transmiss...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-015-0881-7

    authors: Otranto D,Dantas-Torres F

    更新日期:2015-05-14 00:00:00

  • Rapid detection of Babesia motasi responsible for human babesiosis by cross-priming amplification combined with a vertical flow.

    abstract:BACKGROUND:Babesia motasi is known as an etiological agent of human and ovine babesiosis. Diagnosis of babesiosis is traditionally performed by microscopy, examining Giemsa-stained thin peripheral blood smears. Rapid detection and accurate identification of species are desirable for clinical care and epidemiological st...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-020-04246-4

    authors: Wang J,Gao S,Zhang S,He X,Liu J,Liu A,Li Y,Liu G,Luo J,Guan G,Yin H

    更新日期:2020-07-29 00:00:00

  • Nucleoside triphosphate diphosphohydrolase1 (TcNTPDase-1) gene expression is increased due to heat shock and in infective forms of Trypanosoma cruzi.

    abstract:BACKGROUND:Ecto-Nucleoside Triphosphate Diphosphohydrolases (Ecto-NTPDases) are enzymes that hydrolyze tri- and/or di-phosphate nucleotides. Evidences point to their participation in Trypanosoma cruzi virulence and infectivity. In this work, we evaluate TcNTPDase-1 gene expression in comparison with ecto-NTPDase activi...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-014-0463-0

    authors: Silva-Gomes NL,Ennes-Vidal V,Carolo JC,Batista MM,Soeiro MN,Menna-Barreto R,Moreira OC

    更新日期:2014-10-05 00:00:00

  • Characterization of the microbiota in the guts of Triatoma brasiliensis and Triatoma pseudomaculata infected by Trypanosoma cruzi in natural conditions using culture independent methods.

    abstract:BACKGROUND:Chagas disease is caused by Trypanosoma cruzi, which is transmitted by triatomine vectors. The northeastern region of Brazil is endemic for Chagas disease and has the largest diversity of triatomine species. T. cruzi development in its triatomine vector depends on diverse factors, including the composition o...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-015-0836-z

    authors: Gumiel M,da Mota FF,Rizzo Vde S,Sarquis O,de Castro DP,Lima MM,Garcia Ede S,Carels N,Azambuja P

    更新日期:2015-04-24 00:00:00

  • Isolation and identification of Xenorhabdus and Photorhabdus bacteria associated with entomopathogenic nematodes and their larvicidal activity against Aedes aegypti.

    abstract:BACKGROUND:Aedes aegypti is a potential vector of West Nile, Japanese encephalitis, chikungunya, dengue and Zika viruses. Alternative control measurements of the vector are needed to overcome the problems of environmental contamination and chemical resistance. Xenorhabdus and Photorhabdus are symbionts in the intestine...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-017-2383-2

    authors: Fukruksa C,Yimthin T,Suwannaroj M,Muangpat P,Tandhavanant S,Thanwisai A,Vitta A

    更新日期:2017-09-21 00:00:00

  • Toxoplasma gondii in the Eurasian kestrel (Falco tinnunculus) in northern Italy.

    abstract:BACKGROUND:Identifying factors that sustain parasite transmission is important for understanding their spread and emergence, including how changes in biodiversity may affect parasite prevalence and spread. Toxoplasma gondii is a protozoan parasite infecting humans and animals. Birds can acquire T. gondii infection thro...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-020-04134-x

    authors: Iemmi T,Vismarra A,Mangia C,Zanin R,Genchi M,Lanfranchi P,Kramer LH,Formenti N,Ferrari N

    更新日期:2020-05-19 00:00:00

  • Fluralaner as a novel treatment for sarcoptic mange in the bare-nosed wombat (Vombatus ursinus): safety, pharmacokinetics, efficacy and practicable use.

    abstract:BACKGROUND:Sarcoptic mange causes significant animal welfare and occasional conservation concerns for bare-nosed wombats (Vombatus ursinus) throughout their range. To date, in situ chemotherapeutic interventions have involved macrocytic lactones, but their short duration of action and need for frequent re-administratio...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-020-04500-9

    authors: Wilkinson V,Tokano K,Nichols D,Martin A,Holme R,Phalen D,Mounsey K,Charleston M,Kreiss A,Pye R,Browne E,Næsborg-Nielsen C,Richards SA,Carver S

    更新日期:2021-01-06 00:00:00

  • Molecular fingerprinting of the myxozoan community in common carp suffering swim bladder inflammation (SBI) identifies multiple etiological agents.

    abstract:BACKGROUND:Swim bladder inflammation (SBI) is an important disease of common carp fingerlings in Central Europe. In the 1980s, its etiology was ascribed to multicellular proliferative stages of the myxozoan parasite Sphaerospora dykovae (formerly S. renicola). S. dykovae was reported to proliferate in the blood and in ...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-7-398

    authors: Holzer AS,Hartigan A,Patra S,Pecková H,Eszterbauer E

    更新日期:2014-08-28 00:00:00

  • In vitro culture of Echinococcus multilocularis producing protoscoleces and mouse infection with the cultured vesicles.

    abstract:BACKGROUND:Alveolar echinococcosis (AE) is a lethal zoonosis caused by the fox-tapeworm Echinococcus multilocularis. The disease is difficult to treat and an effective therapeutic drug is urgently needed. Reliable models are essential for drug development. In this study, we developed both in vitro and in vivo models of...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-016-1687-y

    authors: Wang H,Li J,Guo B,Zhao L,Zhang Z,McManus DP,Wen H,Zhang W

    更新日期:2016-07-25 00:00:00

  • Spatial risk analysis for the introduction and circulation of six arboviruses in the Netherlands.

    abstract:BACKGROUND:Arboviruses are a growing public health concern in Europe, with both endemic and exotic arboviruses expected to spread further into novel areas in the next decades. Predicting where future outbreaks will occur is a major challenge, particularly for regions where these arboviruses are not endemic. Spatial mod...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-020-04339-0

    authors: Esser HJ,Liefting Y,Ibáñez-Justicia A,van der Jeugd H,van Turnhout CAM,Stroo A,Reusken CBEM,Koopmans MPG,de Boer WF

    更新日期:2020-09-10 00:00:00

  • Analysis of age-dependent trends in Ov16 IgG4 seroprevalence to onchocerciasis.

    abstract:BACKGROUND:Diagnostics provide a means to measure progress toward disease elimination. Many countries in Africa are approaching elimination of onchocerciasis after successful implementation of mass drug administration programs as well as vector control. An understanding of how markers for infection such as skin snip mi...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-016-1623-1

    authors: Golden A,Faulx D,Kalnoky M,Stevens E,Yokobe L,Peck R,Karabou P,Banla M,Rao R,Adade K,Gantin RG,Komlan K,Soboslay PT,de Los Santos T,Domingo GJ

    更新日期:2016-06-13 00:00:00

  • Genetic, serological and biochemical characterization of Leishmania tropica from foci in northern Palestine and discovery of zymodeme MON-307.

    abstract:BACKGROUND:Many cases of cutaneous leishmaniasis (CL) have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth. METHODS:Leishmanial parasites isolated from 12 human cases of CL from the Jenin District were cultured as promastigotes, whose DNA w...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-5-121

    authors: Azmi K,Schnur L,Schonian G,Nasereddin A,Pratlong F,El Baidouri F,Ravel C,Dedet JP,Ereqat S,Abdeen Z

    更新日期:2012-06-18 00:00:00

  • Canine and feline vector-borne diseases in Italy: current situation and perspectives.

    abstract::In Italy, dogs and cats are at risk of becoming infected by different vector-borne pathogens, including protozoa, bacteria, and helminths. Ticks, fleas, phlebotomine sand flies, and mosquitoes are recognized vectors of pathogens affecting cats and dogs, some of which (e.g., Anaplasma phagocytophilum, Borrelia burgdorf...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-3-2

    authors: Otranto D,Dantas-Torres F

    更新日期:2010-01-11 00:00:00

  • Spatio-temporal occurrence of Culicoides biting midges in the climatic regions of Switzerland, along with large scale species identification by MALDI-TOF mass spectrometry.

    abstract:BACKGROUND:Culicoides biting midges are incriminated as biological vectors of a number of viruses, e.g. bluetongue virus. In order to define vector-free periods/areas and to assess the vectorial role of the various Culicoides species, a comprehensive knowledge on their spatio-temporal occurrence is required. METHODS:B...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-5-246

    authors: Kaufmann C,Steinmann IC,Hegglin D,Schaffner F,Mathis A

    更新日期:2012-10-31 00:00:00

  • High prevalence of Toxoplasma gondii oocyst shedding in stray and pet cats (Felis catus) in Virginia, United States.

    abstract:BACKGROUND:The protozoan Toxoplasma gondii is the causative agent of toxoplasmosis, with complications varying from mental disease to death. While human infection can occur via ingestion of tissue cysts from infected meat, most human infection comes from oocysts. Cats are the only definitive host, and thus shedding of ...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-6-266

    authors: Lilly EL,Wortham CD

    更新日期:2013-09-17 00:00:00

  • Impact of repeated ivermectin treatments against onchocerciasis on the transmission of loiasis: an entomologic evaluation in central Cameroon.

    abstract:BACKGROUND:Annual community-directed treatment with ivermectin (CDTI) have been carried out since 1999 in the Lekie division (central region of Cameroon where most cases of Loa-related post ivermectin severe adverse events were reported) as part of the joined activities of the African Programme for Onchocerciasis Contr...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-6-283

    authors: Kouam MK,Tchatchueng-Mbougua JB,Demanou M,Boussinesq M,Pion SD,Kamgno J

    更新日期:2013-09-27 00:00:00

  • Insecticide resistance mechanisms with novel 'kdr' type gene mutations in the tropical bed bug Cimex hemipterus.

    abstract:BACKGROUND:The tropical bed bug, Cimex hemipterus, is a serious indoor public health pest in tropical regions causing intense physical discomfort and mental distress to humans. At present, the application of insecticides is the major control strategy. The present study was designed to evaluate the development of resist...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-019-3565-x

    authors: Punchihewa R,de Silva WAPP,Weeraratne TC,Karunaratne SHPP

    更新日期:2019-06-21 00:00:00

  • The colonization of pyrethroid resistant strain from wild Anopheles sinensis, the major Asian malaria vector.

    abstract:BACKGROUND:Anopheles sinensis is one of the most important malaria vectors in Asian countries. The rapid spread of insecticide resistance has become a major obstacle for insecticide-based strategies for vector control. Therefore, it is necessary to prepare an insecticide-resistant strain of An. sinensis to further unde...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-014-0582-7

    authors: Zhu G,Zhou H,Li J,Tang J,Bai L,Wang W,Gu Y,Liu Y,Lu F,Cao Y,Zhang C,Xu S,Cao J,Gao Q

    更新日期:2014-12-11 00:00:00

  • Genetic homogeneity among Leishmania (Leishmania) infantum isolates from dog and human samples in Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil.

    abstract:BACKGROUND:Certain municipalities in the Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil, have the highest human visceral leishmaniasis (VL) mortality rates in the country and also demonstrate high canine seropositivity. In Brazil, the etiologic agent of VL is Leishmania (Leishmania) infantum. The aim of ...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-015-0837-y

    authors: da Silva TA,Gomes LI,Oliveira E,Coura-Vital W,Silva Lde A,Pais FS,Ker HG,Reis AB,Rabello A,Carneiro M

    更新日期:2015-04-15 00:00:00

  • The Namaqua rock mouse (Micaelamys namaquensis) as a potential reservoir and host of arthropod vectors of diseases of medical and veterinary importance in South Africa.

    abstract:BACKGROUND:The role of endemic murid rodents as hosts of arthropod vectors of diseases of medical and veterinary significance is well established in the northern hemisphere. In contrast, endemic murids are comparatively understudied as vector hosts in Africa, particularly in South Africa. Considering the great rodent d...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-7-366

    authors: Fagir DM,Ueckermann EA,Horak IG,Bennett NC,Lutermann H

    更新日期:2014-08-15 00:00:00

  • Field clinical study evaluating the efficacy and safety of an oral formulation containing milbemycin oxime/praziquantel (Milbemax®, Novartis Animal Health) in the chemoprevention of the zoonotic canine infection by Dirofilaria repens.

    abstract:BACKGROUND:Dirofilaria repens is the causative agent of subcutaneous dirofilariosis of dogs, other animals and humans. This nematode is transmitted by mosquitoes of Aedes, Anopheles and Culex genera. In dogs, the parasite may cause subclinical infection or cutaneous signs. Recently, D. repens has emerged and spread in ...

    journal_title:Parasites & vectors

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1756-3305-7-347

    authors: Di Cesare A,Braun G,Di Giulio E,Paoletti B,Aquilino V,Bartolini R,La Torre F,Meloni S,Drake J,Pandolfi F,Avolio S,Traversa D

    更新日期:2014-07-29 00:00:00

  • A cross-sectional study of the filarial and Leishmania co-endemicity in two ecologically distinct settings in Mali.

    abstract:BACKGROUND:Filariasis and leishmaniasis are two neglected tropical diseases in Mali. Due to distribution and associated clinical features, both diseases are of concern to public health. The goal of this study was to determine the prevalence of co-infection with filarial (Wuchereria bancrofti and Mansonella perstans) an...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-017-2531-8

    authors: Sangare MB,Coulibaly YI,Coulibaly SY,Coulibaly ME,Traore B,Dicko I,Sissoko IM,Samake S,Traore SF,Nutman TB,Valenzuela JG,Faye O,Kamhawi S,Oliveira F,Semnani RT,Doumbia S

    更新日期:2018-01-08 00:00:00

  • Environmental suitability for lymphatic filariasis in Nigeria.

    abstract:BACKGROUND:Lymphatic filariasis (LF) is a mosquito-borne parasitic disease and a major cause of disability worldwide. It is one of the neglected tropical diseases identified by the World Health Organization for elimination as a public health problem by 2020. Maps displaying disease distribution are helpful tools to ide...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-018-3097-9

    authors: Eneanya OA,Cano J,Dorigatti I,Anagbogu I,Okoronkwo C,Garske T,Donnelly CA

    更新日期:2018-09-17 00:00:00

  • Field efficacy and safety of a novel oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against naturally acquired gastrointestinal nematode infections in dogs presented as veterinary patients in Europe and the USA.

    abstract:BACKGROUND:Gastrointestinal nematodes are parasites that commonly infect dogs, and infections can be subclinical or may cause considerable clinical disease. Some species are zoonotic and may also cause clinical disease in humans. Year-round treatment of dogs is recommended to eliminate existing infections, which also i...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-020-3947-0

    authors: Becskei C,Kryda K,Fias D,Follis SL,Wozniakiewicz M,Mahabir SP,Farkas R

    更新日期:2020-03-01 00:00:00

  • Molecular typing of Trichomonas vaginalis isolates by actin gene sequence analysis and carriage of T. vaginalis viruses.

    abstract:BACKGROUND:The protozoan parasite Trichomonas vaginalis is the most common non-viral, sexually transmitted pathogen. Although T. vaginalis is highly prevalent among women in Kenya, there is lack of data regarding genetic diversity of isolates currently in circulation in Kenya. METHODS:Typing was performed on 22 clinic...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-017-2496-7

    authors: Masha SC,Cools P,Crucitti T,Sanders EJ,Vaneechoutte M

    更新日期:2017-10-30 00:00:00

  • Neurotoxocarosis: marked preference of Toxocara canis for the cerebrum and T. cati for the cerebellum in the paratenic model host mouse.

    abstract:BACKGROUND:Infective larvae of the worldwide occurring zoonotic roundworm T. canis exhibit a marked affinity to the nervous tissues of paratenic hosts. In humans, most cases of neurotoxocarosis are considered to be caused by larvae of T. canis as T. cati larvae have rarely been found in the CNS in previous studies. How...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/1756-3305-7-194

    authors: Janecek E,Beineke A,Schnieder T,Strube C

    更新日期:2014-04-22 00:00:00

  • A novel progesterone receptor membrane component (PGRMC) in the human and swine parasite Taenia solium: implications to the host-parasite relationship.

    abstract:BACKGROUND:We have previously reported that progesterone (P4) has a direct in vitro effect on the scolex evagination and growth of Taenia solium cysticerci. Here, we explored the hypothesis that the P4 direct effect on T. solium might be mediated by a novel steroid-binding parasite protein. METHODS:By way of using imm...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-018-2703-1

    authors: Aguilar-Díaz H,Nava-Castro KE,Escobedo G,Domínguez-Ramírez L,García-Varela M,Del Río-Araiza VH,Palacios-Arreola MI,Morales-Montor J

    更新日期:2018-03-09 00:00:00

  • NLRP3 inflammasome activation from Kupffer cells is involved in liver fibrosis of Schistosoma japonicum-infected mice via NF-κB.

    abstract:BACKGROUND:NOD-like receptor protein 3 (NLRP3) inflammasome was reported as expressed in schistosomiasis-induced liver fibrosis (SSLF). We used an NLRP3 inflammasome inhibitor, MCC950, to investigate whether it inhibited liver fibrosis, and explored the preliminary molecular mechanism. METHODS:BALB/c mice were infecte...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-018-3223-8

    authors: Zhang WJ,Fang ZM,Liu WQ

    更新日期:2019-01-11 00:00:00

  • Reservoir hosts for Gyrodactylus salaris may play a more significant role in epidemics than previously thought.

    abstract:BACKGROUND:Gyrodactylus salaris Malmberg, 1957 has had a devastating impact on wild Norwegian stocks of Atlantic salmon Salmo salar L., and it is the only Office International des Epizooties (OIE) listed parasitic pathogen of fish. The UK is presently recognised as G. salaris-free, and management plans for its containm...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-014-0576-5

    authors: Paladini G,Hansen H,Williams CF,Taylor NG,Rubio-Mejía OL,Denholm SJ,Hytterød S,Bron JE,Shinn AP

    更新日期:2014-12-20 00:00:00

  • Vaccination of mice with a recombinant novel cathepsin B inhibits Trichinella spiralis development, reduces the fecundity and worm burden.

    abstract:BACKGROUND:Trichinella spiralis is a major zoonotic tissue-dwelling nematode, which is a public health concern and a serious hazard to animal food safety. It is necessary to exploit an anti-Trichinella vaccine to interrupt the transmission of Trichinella infection among animals and from animals to humans. The purpose o...

    journal_title:Parasites & vectors

    pub_type: 杂志文章

    doi:10.1186/s13071-019-3833-9

    authors: Cui J,Han Y,Yue X,Liu F,Song YY,Yan SW,Lei JJ,Zhang X,Jiang P,Wang ZQ

    更新日期:2019-12-11 00:00:00