Abstract:
:In hepatocellular carcinoma (HCC) patients, the intratumoral expression of Toll-like receptor-3 (TLR3) correlates with prolonged survival. We demonstrated that TLR3 ligands can operate through three independent mechanisms: by directly killing TLR3-expressing cancer cells, by inducing T- and natural killer (NK)-cell infiltration and by activating TLR3-expressing NK cells.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Chew V,Abastado JPdoi
10.4161/onci.23493subject
Has Abstractpub_date
2013-04-01 00:00:00pages
e23493issue
4eissn
2162-4011issn
2162-402Xpii
2013ONCOIMM0001journal_volume
2pub_type
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