Development of coronary artery stenosis in a patient with metastatic renal cell carcinoma treated with sorafenib.

abstract：BACKGROUND:UroVysion fluorescence in situ hybridization (uFISH) was reported to have superior sensitivity to urine cytology. However uFISH studies are limited by varying definitions of what is considered a positive result, absence of histopathology and small sample size. The aim of our study was to better determine the...

journal_title：BMC cancer

authors： Lavery HJ,Zaharieva B,McFaddin A,Heerema N,Pohar KS

更新日期：2017-04-07 00:00:00

abstract：BACKGROUND:Oxidative damage to mitochondrial DNA has been implicated as a causative factor in a wide variety of degenerative diseases, aging and cancer. The modified guanine, 7,8-dihydro-8-oxoguanine (also known as 8-hydroxyguanine) is one of the major oxidized bases generated in DNA by reactive oxygen species and has ...

journal_title：BMC cancer

authors： Chatterjee A,Mambo E,Zhang Y,Deweese T,Sidransky D

更新日期：2006-10-03 00:00:00

abstract：BACKGROUND:Patients with hepatocellular carcinoma waiting for liver transplantation are commonly treated with locoregional treatments, such as TACE and ablation, to prevent tumor progression and dropout and to improve long-term outcome after transplantation. We wanted to prospectively assess feasibility of systemic ant...

journal_title：BMC cancer

authors： Eilard MS,Andersson M,Naredi P,Geronymakis C,Lindnér P,Cahlin C,Bennet W,Rizell M

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:RNA from exosomes and other microvesicles contain transcripts of tumour origin. In this study we sought to identify biomarkers of glioblastoma multiforme in microvesicle RNA from serum of affected patients. METHODS:Microvesicle RNA from serum from patients with de-novo primary glioblastoma multiforme (N = 9...

journal_title：BMC cancer

authors： Noerholm M,Balaj L,Limperg T,Salehi A,Zhu LD,Hochberg FH,Breakefield XO,Carter BS,Skog J

更新日期：2012-01-17 00:00:00

abstract：BACKGROUND:Worldwide, acute leukemia is the most common type of childhood cancer. It is particularly common in the Hispanic populations residing in the United States, Costa Rica, and Mexico City. The objective of this study was to determine the incidence of acute leukemia in children who were diagnosed and treated in p...

journal_title：BMC cancer

authors： Pérez-Saldivar ML,Fajardo-Gutiérrez A,Bernáldez-Ríos R,Martínez-Avalos A,Medina-Sanson A,Espinosa-Hernández L,Flores-Chapa Jde D,Amador-Sánchez R,Peñaloza-González JG,Alvarez-Rodríguez FJ,Bolea-Murga V,Flores-Lujano J,Rodríguez-Z

更新日期：2011-08-17 00:00:00

abstract：BACKGROUND:Neoadjuvant systemic therapy (NST) is increasingly used in the treatment of breast cancer, yet it is clear that there is significant geographical variation in its use in the UK. This study aimed to examine stated practice across UK breast units, in terms of indications for use, radiological monitoring, patho...

journal_title：BMC cancer

authors： Whitehead I,Irwin GW,Bannon F,Coles CE,Copson E,Cutress RI,Dave RV,Gardiner MD,Grayson M,Holcombe C,Irshad S,O'Brien C,O'Connell RL,Palmieri C,Shaaban AM,Sharma N,Singh JK,Potter S,McIntosh SA,NeST Study Research Co

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate epigenetic status of cyclin A1 in human papillomavirus-associated cervical cancer. Y. Tokumaru et al., Cancer Res 64, 5982-7 (Sep 1, 2004)demonstrated in head and neck squamous-cell cancer an inverse correlation between cyclin A1 promoter hypermethylation and TP53 mutati...

journal_title：BMC cancer

authors： Kitkumthorn N,Yanatatsanajit P,Kiatpongsan S,Phokaew C,Triratanachat S,Trivijitsilp P,Termrungruanglert W,Tresukosol D,Niruthisard S,Mutirangura A

更新日期：2006-03-08 00:00:00

abstract：BACKGROUND:Worldwide cervical cancer is the third most common malignancy in women. It usually arises from the cervical area which is susceptible to Human Papilloma virus induced malignancy changes. In low-resource setting visual inspection with acetic acid (VIA) is an alternative sensitive cervical screening method. Th...

journal_title：BMC cancer

authors： Hailemariam G,Gebreyesus H,Wubayehu T,Gebregyorgis T,Gebrecherkos K,Teweldemedhin M,Kifle M

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:BCOR acts as a corepressor of BCL6, a potent oncogenic protein in cancers of the lymphoid lineage. We have found the recurrent somatic mutation of BCOR occurred in mature T-cell lymphoma (TCL). The role of BCOR mutation in lymphoid malignancies is unknown. METHODS:Lymphoma patient samples were analyzed to i...

journal_title：BMC cancer

authors： Kang JH,Lee SH,Lee J,Choi M,Cho J,Kim SJ,Kim WS,Ko YH,Yoo HY

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:It is well known that women suffer from negative consequences following breast cancer (BC) treatment and that their largely varying needs for rehabilitation are often unmet. Up to 43% of these women are at risk of developing chronic distress requiring complex interventions; however, how to early identify and...

journal_title：BMC cancer

authors： Olsson Möller U,Rydén L,Malmström M

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:Quantifying the response of cell lines to drugs or other perturbagens is the cornerstone of pre-clinical drug development and pharmacogenomics as well as a means to study factors that contribute to sensitivity and resistance. In dividing cells, traditional metrics derived from dose-response curves such as IC...

journal_title：BMC cancer

authors： Clark NA,Hafner M,Kouril M,Williams EH,Muhlich JL,Pilarczyk M,Niepel M,Sorger PK,Medvedovic M

更新日期：2017-10-24 00:00:00

abstract：BACKGROUND:Territorial differences in the access to innovative anticancer drugs have been reported from many countries. The objectives of this study were to evaluate access to innovative treatments for metastatic lung cancer in France, and to assess whether socioeconomic indicators were predictors of access at the leve...

journal_title：BMC cancer

authors： Scherpereel A,Durand-Zaleski I,Cotté FE,Fernandes J,Debieuvre D,Blein C,Gaudin AF,Tournier C,Vainchtock A,Chauvin P,Souquet PJ,Westeel V,Chouaïd C

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Total mesorectal excision is the standard surgical treatment for mid- and low-rectal cancer. Laparoscopy represents a clear leap forward in the management of rectal cancer patients, offering significant improvements in post-operative measures such as pain, first bowel movement, and hospital length of stay. H...

journal_title：BMC cancer

authors： Lelong B,de Chaisemartin C,Meillat H,Cournier S,Boher JM,Genre D,Karoui M,Tuech JJ,Delpero JR,French Research Group of Rectal Cancer Surgery (GRECCAR).

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Patients with unresectable malignant biliary obstruction have limited life expectancy because of limited stent patency and tumor progression. The aim of our study was to retrospectively evaluate the safety and efficacy of combining intraductal RFA with biliary metal stent placement for patients with malignan...

journal_title：BMC cancer

authors： Cui W,Fan W,Lu M,Zhang Y,Yao W,Li J,Wang Y

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:Altered expression of microRNAs (miRNAs) is known to contribute to cancer progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported to have both tumor suppressive and oncogenic activity across human cancers, including breast cancer. METHODS:To clarify this dichotomous role in bre...

journal_title：BMC cancer

authors： Hannafon BN,Cai A,Calloway CL,Xu YF,Zhang R,Fung KM,Ding WQ

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:Response-guided neoadjuvant chemotherapy (RG-NACT) with magnetic resonance imaging (MRI) is effective in treating oestrogen receptor positive/human epidermal growth factor receptor-2 negative (ER-positive/HER2-negative) breast cancer. We estimated the expected cost-effectiveness and resources required for it...

journal_title：BMC cancer

authors： Miquel-Cases A,Steuten LM,Rigter LS,van Harten WH

更新日期：2016-09-05 00:00:00

abstract：:It has been highlighted that the original manuscript [1] contains a typesetting error in the surname of Jesson Butcon. This was incorrectly captured as Jessica Butcon in the original manuscript which has since been updated. ...

journal_title：BMC cancer

authors： Chan RJ,Yates P,Li Q,Komatsu H,Lopez V,Thandar M,Chacko ST,So WKW,Pongthavornkamol K,Yi M,Pittayapan P,Butcon J,Wyld D,Molassiotis A,STEP study collaborators.

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The human leucine-rich, repeat-containing G protein-coupled receptor 5 (LGR5) is a stem cell marker in numerous adult tissues and is overexpressed in a large number of human carcinoma including colon cancer, breast cancer and oral squamous cell carcinomas (OSCC). The role of the full length transcript (LGR5F...

journal_title：BMC cancer

authors： Rot S,Kaune T,Taubert H,Greither T,Kotrba J,Güttler A,Wichmann H,Bilkenroth U,Wienke A,Al-Nawas B,Bache M,Vordermark D,Wickenhauser C,Bethmann D,Eckert AW,Kappler M

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:Solitary plasmacytoma (SP) is a localized neoplastic plasma cell disorder with an annual incidence of less than 450 cases. Given the rarity of this disorder, it is difficult to conduct large-scale population studies. Consequently, very limited information on the disorder is available, making it difficult to ...

journal_title：BMC cancer

authors： Thumallapally N,Meshref A,Mousa M,Terjanian T

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:Deciphering the meaning of the human DNA is an outstanding goal which would revolutionize medicine and our way for treating diseases. In recent years, non-coding RNAs have attracted much attention and shown to be functional in part. Yet the importance of these RNAs especially for higher biological functions ...

journal_title：BMC cancer

authors： Smolander J,Stupnikov A,Glazko G,Dehmer M,Emmert-Streib F

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Whether perioperative blood transfusions (PBTs) adversely influence oncological outcomes for intrahepatic cholangiocarcinoma (ICC) patients after curative resection remains undetermined. METHODS:Of the 605 patients who underwent curative liver resection for ICC between 2000 and 2012, 93 received PBT. We con...

journal_title：BMC cancer

authors： Zhou PY,Tang Z,Liu WR,Tian MX,Jin L,Jiang XF,Wang H,Tao CY,Ding ZB,Peng YF,Qiu SJ,Dai Z,Zhou J,Fan J,Shi YH

更新日期：2017-11-14 00:00:00

abstract：BACKGROUND:Previous data from our laboratory has indicated that there is a functional link between the beta-adrenergic receptor signaling pathway and the G-protein inwardly rectifying potassium channel (GIRK1) in human breast cancer cell lines. We wanted to determine if GIRK channels were expressed in lung cancers and ...

journal_title：BMC cancer

authors： Plummer HK 3rd,Dhar MS,Cekanova M,Schuller HM

更新日期：2005-08-18 00:00:00

abstract：BACKGROUND:Amphiregulin (AREG) and Epiregulin (EREG), ligands of EGFR, are reported to be predictive biomarkers of colorectal cancer patients treated with Cetuximab, an anti-EGFR antibody. The purpose of this study is to determine the correlation of AREG and EREG expression between primary colorectal cancer and corresp...

journal_title：BMC cancer

authors： Kuramochi H,Nakajima G,Kaneko Y,Nakamura A,Inoue Y,Yamamoto M,Hayashi K

更新日期：2012-03-13 00:00:00

abstract：BACKGROUND:Success of cancer prodrugs relying on a foreign gene requires specific delivery of the gene to the cancer, and improvements such as higher level gene transfer and expression. Attaining these objectives will be facilitated in preclinical studies using our newly discovered CNOB-GDEPT, consisting of the produrg...

journal_title：BMC cancer

authors： Wang JH,Endsley AN,Green CE,Matin AC

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the most aggressive cancers lacking efficient early detection biomarkers. Circulating miRNAs are now being considered to have potency to be used as diagnostic and prognostic biomarkers in different diseases as well as cancers. In case of cancer,...

journal_title：BMC cancer

authors： Chhatriya B,Mukherjee M,Ray S,Sarkar P,Chatterjee S,Nath D,Das K,Goswami S

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:The miRNA isoforms (isomiRs) have been suggested to regulate the same pathways as the canonical miRNA and play an important biological role in miRNA-mediated gene regulation. Recently, a study has demonstrated that the presence or absence of all isomiRs could efficiently discriminate amongst 32 TCGA cancer t...

journal_title：BMC cancer

authors： Wang S,Zheng Z,Chen P,Wu M

更新日期：2019-02-07 00:00:00

abstract：BACKGROUND:Whether chronic inflammation increases prostate cancer risk remains unclear. This study investigated whether chronic inflammatory diseases (CID) or anti-inflammatory medication use (AIM) were associated with prostate cancer risk. METHODS:Fifty-five thousand nine hundred thirty-seven cases (all prostate canc...

journal_title：BMC cancer

authors： Beckmann K,Russell B,Josephs D,Garmo H,Haggstrom C,Holmberg L,Stattin P,Van Hemelrijck M,Adolfsson J

更新日期：2019-06-21 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate the association between matrix metalloproteinase-9 (MMP-9) expression with BRAF V600E mutation and clinicopathological features, in Iranian papillary thyroid cancer (PTC) patients. METHODS:In total, 90 participants including 60 PTC patients (15 males and 45 fe...

journal_title：BMC cancer

authors： Zarkesh M,Zadeh-Vakili A,Akbarzadeh M,Fanaei SA,Hedayati M,Azizi F

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND:Of all female genital tract tumors, 1-3% are stromal malignancies. In 8-10% of cases, these are represented by Müllerian adenosarcoma an extremely rare tumor characterized by a stromal component of usually low-grade malignancy and by a benign glandular epithelial component. Variant that arises in the pouch o...

journal_title：BMC cancer

authors： Patrelli TS,Silini EM,Gizzo S,Berretta R,Franchi L,Thai E,Lukanovic A,Nardelli GB,Modena AB

更新日期：2011-05-15 00:00:00

abstract：BACKGROUND:Recent reports indicate the existence of breast cancer cells expressing very high levels of the Arylhydrocarbon receptor (AhR), a ubiquitous intracellular receptor best known for mediating toxic action of dioxin and related pollutants. Positive correlation between the degree of AhR overexpression and states ...

journal_title：BMC cancer

authors： Wong PS,Li W,Vogel CF,Matsumura F

更新日期：2009-07-15 00:00:00