Abstract：
: Microbiologists have extensively worked during the past decade on a particular phase of the bacterial cell cycle known as biofilm, in which single-celled individuals gather together to form a sedentary but dynamic community within a complex structure, displaying spatial and functional heterogeneity. In response to the perception of environmental signals by sensing systems, appropriate responses are triggered, leading to biofilm formation. This process involves various molecular systems that enable bacteria to identify appropriate surfaces on which to anchor themselves, to stick to those surfaces and to each other, to construct multicellular communities several hundreds of micrometers thick, and to detach from the community. The biofilm microbial community is a unique, highly competitive, and crowded environment facilitating microevolutionary processes and horizontal gene transfer between distantly related microorganisms. It is governed by social rules, based on the production and use of "public" goods, with actors and recipients. Biofilms constitute a unique shield against external aggressions, including drug treatment and immune reactions. Biofilm-associated infections in humans have therefore generated major problems for the diagnosis and treatment of diseases. Improvements in our understanding of biofilms have led to innovative research designed to interfere with this process.
journal_name
Ann Intensive Carejournal_title
Annals of intensive careauthors
Bordi C,de Bentzmann Sdoi
10.1186/2110-5820-1-19subject
Has Abstractpub_date
2011-06-13 00:00:00pages
19issue
1issn
2110-5820pii
2110-5820-1-19journal_volume
1pub_type
杂志文章abstract：BACKGROUND:Venous thromboembolism (VTE) is one of the most common preventable causes of in-hospital death in trauma patients surviving their injuries. We assessed the prevalence, incidence and risk factors for deep venous thrombosis (DVT) and pulmonary embolism (PE) in critically ill trauma patients, in the setting of ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0315-0
更新日期：2017-09-12 00:00:00
abstract：:The death of a loved one is often an ordeal and a tragedy for those who witness it, as death is not merely the end of a life, but also the end of an existence, the loss of a unique individual who is special and irreplaceable. In some situations, end-of-life signs, such as agonal gasps, can be an almost unbearable "sig...
journal_title：Annals of intensive care
pub_type： 杂志文章,评审
doi：10.1186/2110-5820-4-23
更新日期：2014-07-08 00:00:00
abstract：BACKGROUND:The effects of perioperative statin therapy on clinical outcome after cardiac or non-cardiac surgery are controversial. We aimed to assess the association between perioperative statin therapy and postoperative outcome. METHODS:Electronic databases were searched up to May 1, 2018, for randomized controlled t...
journal_title：Annals of intensive care
pub_type： 杂志文章,评审
doi：10.1186/s13613-018-0441-3
更新日期：2018-09-27 00:00:00
abstract：BACKGROUND:Assessment of maximum respiratory pressures is a common practice in intensive care because it can predict the success of weaning from ventilation. However, the reliability of measurements through an intubation catheter has not been compared with standard measurements. The aim of this study was to compare max...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0362-1
更新日期：2018-01-30 00:00:00
abstract：BACKGROUND:Pendelluft, the movement of gas within different lung regions, is present in animal models of assisted mechanical ventilation and associated with lung overstretching. Due to rebreathing of CO2 as compared to fresh gas, pendelluft might reduce ventilatory efficiency possibly exacerbating patient's respiratory...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00654-y
更新日期：2020-04-07 00:00:00
abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) patients may present impaired in lung function and structure after hospital discharge that may be related to mechanical ventilation strategy. The aim of this study was to evaluate the association between functional and structural lung impairment, N-terminal-peptide ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0469-4
更新日期：2018-12-07 00:00:00
abstract：BACKGROUND:cRel, a subunit of NF-κB, is implicated in the inflammatory response observed in autoimmune disease. Hence, knocked-out mice for cRel had a significantly higher mortality, providing new and important functions of cRel in the physiopathology of septic shock. Whether genetic variants in the human REL gene are ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-016-0130-z
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:We assessed the association of intravenous insulin and glucose infusion with intensive care unit (ICU) and hospital mortality. METHODS:For this retrospective association study, we used data from all patients admitted to a medical-surgical ICU between January 2012 and September 2017. We excluded patients adm...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0507-x
更新日期：2019-02-11 00:00:00
abstract：: Cancer is a leading cause of death in children. In the past decades, there has been a marked increase in overall survival of children with cancer. However, children whose treatment includes hematopoietic stem cell transplantation still represent a subpopulation with a higher risk of mortality. These improvements in m...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/2110-5820-2-14
更新日期：2012-06-12 00:00:00
abstract：BACKGROUND:SARS coronavirus 2 (SARS-CoV-2) is responsible for high morbidity and mortality worldwide, mostly due to the exacerbated inflammatory response observed in critically ill patients. However, little is known about the kinetics of the systemic immune response and its association with survival in SARS-CoV-2+ pati...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00798-x
更新日期：2021-01-13 00:00:00
abstract：BACKGROUND:Noninvasive ventilation (NIV) is the first-line treatment of adult patients with exacerbations of cystic fibrosis (CF). High-flow nasal oxygen therapy (HFNT) might benefit patients with hypoxemia and can reduce physiological dead space. We hypothesized that HFNT and NIV would similarly reduce work of breathi...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0432-4
更新日期：2018-09-05 00:00:00
abstract：BACKGROUND:The impact of neutropenia in critically ill immunocompromised patients admitted in a context of acute respiratory failure (ARF) remains uncertain. The primary objective was to assess the prognostic impact of neutropenia on outcomes of these patients. Secondary objective was to assess etiology of ARF accordin...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00764-7
更新日期：2020-10-22 00:00:00
abstract：BACKGROUND:The clinical interest of using bubble humidification of oxygen remains controversial. This study was designed to further explore whether delivering dry oxygen instead of bubble-moistened oxygen had an impact on discomfort of ICU patients. METHODS:This randomized multicenter non-inferiority open trial includ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0472-9
更新日期：2018-12-17 00:00:00
abstract：BACKGROUND:Glucose control is an important issue in post-operative patients. The objective here was to compare two insulin infusion lines by syringe pumps to assess the impact of medical devices on glycaemic variability in surgical patients under intensive insulin therapy. This open, prospective, single-centre randomis...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0298-x
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We have adopted an open-l...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0492-0
更新日期：2019-01-18 00:00:00
abstract：:In the past, the only treatment of acute exacerbations of obstructive diseases with hypercapnic respiratory failure refractory to medical treatment was invasive mechanical ventilation (IMV). Considerable technical improvements transformed extracorporeal techniques for carbon dioxide removal in an attractive option to ...
journal_title：Annals of intensive care
pub_type： 杂志文章,评审
doi：10.1186/s13613-019-0551-6
更新日期：2019-07-02 00:00:00
abstract：BACKGROUND:Despite improvements in intermittent hemodialysis management, intradialytic hemodynamic instability (IHI) remains a common issue that could account for increased mortality and delayed renal recovery. However, predictive factors of IHI remain poorly explored. The objective of this study was to evaluate the re...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00663-x
更新日期：2020-04-22 00:00:00
abstract：BACKGROUND:Occlusion pressure at 100 ms (P0.1), defined as the negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit, has been shown to be well correlated with central respiratory drive and respiratory effort. Automated P0.1 measurement is availab...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0576-x
更新日期：2019-09-13 00:00:00
abstract：BACKGROUND:The Lung Injury Score (LIS) remains a commonly utilized measure of lung injury severity though the additive value of LIS to predict ARDS outcomes over the recent Berlin definition of ARDS, which incorporates severity, is not known. METHODS:We tested the association of LIS (in which scores range from 0 to 4,...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/2110-5820-4-4
更新日期：2014-02-18 00:00:00
abstract：:Jean-Luc Diehl The French Intensive Care Society organized on 5th and 6th June 2014 its 4th "Paris International Conference in Intensive Care", whose principle is to bring together the best international experts on a hot topic in critical care medicine. The 2014 theme was "Breakthrough in cardiac arrest", with many hi...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-015-0064-x
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Mortality of critically ill hematology (HM) patients has improved over time. Thus, those patients require an extensive diagnostic workup and the optimal use of available treatments. There are no data regarding nutrition strategy for critically ill HM patients, while nutritional support is crucial for both HM...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0527-6
更新日期：2019-05-07 00:00:00
abstract：BACKGROUND:Lactate is a robust prognostic marker for the outcome of critically ill patients. Several small studies reported that metformin users have higher lactate levels at ICU admission without a concomitant increase in mortality. However, this has not been investigated in a larger cohort. We aimed to determine whet...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00652-0
更新日期：2020-03-26 00:00:00
abstract：BACKGROUND:The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin (MR-proADM) in predicting mortality in sepsis patients with different degrees of or...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0238-9
更新日期：2017-12-01 00:00:00
abstract：:Although improving, the mortality from septic shock still remains high despite increased international awareness. As a consequence, much effort has focused on alternative treatment strategies in an effort to improve outcomes. The application of blood purification therapies to improve immune homeostasis has been sugges...
journal_title：Annals of intensive care
pub_type： 杂志文章,评审
doi：10.1186/s13613-019-0530-y
更新日期：2019-05-14 00:00:00
abstract：BACKGROUND:Hyponatremia occurring as a result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting syndrome is a common complication in patients with subarachnoid hemorrhage (SAH). The efficacy and safety of urea as treatment for SIADH-induced hyponatremia has not been report...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/2110-5820-2-13
更新日期：2012-05-30 00:00:00
abstract：BACKGROUND:Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-clinical data from mouse, rat, sheep and ex vivo perfused human lung models support the use of human ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-014-0022-z
更新日期：2014-07-03 00:00:00
abstract：BACKGROUND:Knowledge of patients' height is essential for daily practice in the intensive care unit. However, actual height measurements are unavailable on a daily routine in the ICU and measured height in the supine position and/or visual estimates may lack consistency. Clinicians do need simple and rapid methods to e...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-016-0154-4
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE) abnormalities are not well defined. METHODS:Observational study of patients with ARDS, admitted f...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0343-9
更新日期：2017-12-19 00:00:00
abstract：BACKGROUND:Acute kidney injury (AKI) occurs in up to 50% of all critically ill patients and hemodynamic abnormalities are assumed to contribute, but their nature and share is still unclear. We explored the associations between hemodynamic variables, including cardiac index and right ventricular function, and the occurr...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0513-z
更新日期：2019-03-13 00:00:00
abstract：BACKGROUND:Intravenous crystalloid solutions are administered commonly for critically ill patients. We performed this meta-analysis of randomized trials with trial sequential analysis (TSA) to evaluate effects of chloride content of intravenous crystalloid solutions on clinical outcomes among critically ill adult patie...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0506-y
更新日期：2019-02-13 00:00:00
