Membrane sealant Poloxamer P188 protects against isoproterenol induced cardiomyopathy in dystrophin deficient mice.

abstract：BACKGROUND:To help patients with coronary artery disease (CAD) benefit from the positive health effects attained by exercise-based cardiac rehabilitation (CR), adherence to these programmes according to international guidelines is important. Strategies to increase adherence to exercise-based CR are mainly an unexplored...

journal_title：BMC cardiovascular disorders

authors： Borg S,Öberg B,Nilsson L,Söderlund A,Bäck M

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:This study aimed to determine whether midlife obesity predicts heart failure (HF) over an extended follow-up into old age. METHODS:We studied 7495 men (from a population sample of 9,998 men) without HF, who were 47-55 years old when investigated in 1970 to 1973. All participants were followed up for 35 year...

journal_title：BMC cardiovascular disorders

authors： Björck L,Novak M,Schaufelberger M,Giang KW,Rosengren A

更新日期：2015-03-10 00:00:00

abstract：BACKGROUND:The effects on cardiovascular disease (CVD) by treatment recommendations on prevention of atherosclerotic CVD remain to be evaluated. The objectives were to assess treatment gap for low density lipoprotein cholesterol (LDL-C) according to guidelines, potential impact on CVD outcomes, and possible avoided eco...

journal_title：BMC cardiovascular disorders

authors： Journath G,Hambraeus K,Hagström E,Pettersson B,Löthgren M

更新日期：2017-08-16 00:00:00

abstract：BACKGROUND:Previous renal denervation (RDN) studies showed controversial results in reducing blood pressure. The aim of this study was to provide evidence supporting the effectiveness of laparoscopic-based renal denervation (L-RDN) in treating hypertension. METHODS:Sixteen Beagle dogs were randomly divided into RDN gr...

journal_title：BMC cardiovascular disorders

authors： Shao C,Zhou Y,You T,Xue B,Stella PR,Jiang TB,Miao Z,Xu L,Yin,Lan L,Rong G

更新日期：2020-06-11 00:00:00

abstract：BACKGROUND:We characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9. METHODS:Published and individual participant level data (300,000+ participants) were combined to construct a weighted PCSK9 gene-centric score ...

journal_title：BMC cardiovascular disorders

authors： Schmidt AF,Holmes MV,Preiss D,Swerdlow DI,Denaxas S,Fatemifar G,Faraway R,Finan C,Valentine D,Fairhurst-Hunter Z,Hartwig FP,Horta BL,Hypponen E,Power C,Moldovan M,van Iperen E,Hovingh K,Demuth I,Norman K,Steinhagen-

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:In Denmark and other countries, there has been a shift in the management of patients with an implantable cardioverter defibrillator (ICD) with remote device monitoring largely replacing in-hospital visits. Less patient-nurse and patient-physician interaction may lead to gaps in patients' quality of care and ...

journal_title：BMC cardiovascular disorders

authors： Pedersen SS,Skovbakke SJ,Wiil UK,Schmidt T,dePont Christensen R,Brandt CJ,Sørensen J,Vinther M,Larroudé CE,Melchior TM,Riahi S,Smolderen KGE,Spertus JA,Johansen JB,Nielsen JC

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Cardiac fibroblasts, regarded as the immunomodulatory hub of the heart, have been thought to play an important role during sepsis-induced cardiomyopathy (SIC). However, the detailed molecular mechanism and targeted therapies for SIC are still lacking. Therefore, we sought to investigate the likely protective...

journal_title：BMC cardiovascular disorders

authors： Ji J,Liu Z,Hong X,Liu Z,Gao J,Liu J

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Previous studies have found a connection between left coronary artery dominance and worse prognoses in patient with acute coronary syndrome, which remains a predominant cause of morbidity and mortality globally. The aim of this study was to investigate whether coronary dominance is associated with the incide...

journal_title：BMC cardiovascular disorders

authors： Wang L,Li J,Gao Y,Li R,Zhang J,Su D,Wang T,Yang G,Wang X

更新日期：2019-02-04 00:00:00

abstract：BACKGROUND:Heart failure is a major and growing medical and economic problem worldwide as 1-2% of the healthcare budget are spent for heart failure. The prevalence of heart failure has increased over the past decades and it is expected that there will be further raise due to the higher proportion of elderly in the west...

journal_title：BMC cardiovascular disorders

authors： Lesyuk W,Kriza C,Kolominsky-Rabas P

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:We assessed the degree to which differences in guideline-based medical therapy for acute myocardial infarction (AMI) contribute to the higher mortality associated with kidney disease. METHODS:In the PREMIER registry, we evaluated patients from 19 US centers surviving AMI. Cox regression evaluated the associ...

journal_title：BMC cardiovascular disorders

authors： Peterson PN,Ambardekar AV,Jones PG,Krumholz HM,Schelbert E,Spertus JA,Rumsfeld JS,Masoudi FA

更新日期：2009-07-08 00:00:00

abstract：BACKGROUND:Diabetes is one of the major risk factors for cardiomyopathy and heart failure with reduced ejection fraction (EF) and highly associated with left ventricular (LV) dysfunction in human. This study aimed 1) to noninvasively assess cardiac function using echocardiography; 2) to test the hypothesis that like di...

journal_title：BMC cardiovascular disorders

authors： Gu H,Liu Y,Mei S,Wang B,Sun G,Wang X,Xiao Y,Staup M,Gregoire FM,Chng K,Wang YJ

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:Atrial fibrillatory cycle length has been considered one of the indices of atrial electrical remodelling during atrial fibrillation (AF), which can be assessed from surface ECG by computer-assisted calculation of atrial fibrillatory rate (AFR). Horses have been suggested as a bona fide model for AF studies s...

journal_title：BMC cardiovascular disorders

authors： Hesselkilde EZ,Carstensen H,Haugaard MM,Carlson J,Pehrson S,Jespersen T,Buhl R,Platonov PG

更新日期：2017-12-08 00:00:00

abstract：BACKGROUND:Genetic variation at 1p13 modulates serum lipid levels and the risk of coronary heart disease through the regulation of serum lipid levels. Here we investigate if the interaction between genetic variants at 1p13 and serum lipid levels affects the risk of non-fatal myocardial infarction (MI) in the Stockholm ...

journal_title：BMC cardiovascular disorders

authors： Gigante B,Leander K,Vikström M,Ye S,de Faire U

更新日期：2012-10-16 00:00:00

abstract：BACKGROUND:For patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI), the efficacy and safety of novel P2Y12 antagonists, including prasugrel or ticagrelor, has not been established relative to that of the clopidogrel-based triple-antiplatelet treatments (T...

journal_title：BMC cardiovascular disorders

authors： Wang Z,Zhou DY,Su Y,Si LY,Xu Q

更新日期：2020-03-12 00:00:00

abstract：BACKGROUND:Ticagrelor and clopidogrel, P2Y12 receptor antagonists, can prevent thrombotic events and are used to treat cardiovascular diseases such as acute coronary syndrome and chronic obstructive pulmonary disease, in which inflammation is involved. Moreover, NF-B is the central regulator of inflammation. Thus, we s...

journal_title：BMC cardiovascular disorders

authors： Jia Z,Huang Y,Ji X,Sun J,Fu G

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Cardio-metabolic syndrome (CMS) is a highly prevalent condition. There is an urgent need to identify effective and integrated multi-disciplinary approaches that can reduce risk factors for CMS. METHODS:Sixty-two patients with a history of CMS were randomized 1:1 into two groups: a standard information -only...

journal_title：BMC cardiovascular disorders

authors： Zhang Y,Mei S,Yang R,Chen L,Gao H,Li L

更新日期：2016-11-18 00:00:00

abstract：BACKGROUND:Preoperative low left ventricular ejection fraction (LVEF) has been reported as an independent risk factor for in-hospital mortality. However, there were few studies evaluating the long-term mortality in these patients. We, therefore, conducted this study to investigate long-term outcomes of surgery on patie...

journal_title：BMC cardiovascular disorders

authors： Fan FD,Zhang HT,Pan T,Tang XL,Wang DJ

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:Aortic calcification is a major risk factor for death from cardiovascular disease. We investigated the relationship between mortality and the composite markers of number, size, morphology and distribution of calcified plaques in the lumbar aorta. METHODS:308 postmenopausal women aged 48-76 were followed for...

journal_title：BMC cardiovascular disorders

authors： Nielsen M,Ganz M,Lauze F,Pettersen PC,de Bruijne M,Clarkson TB,Dam EB,Christiansen C,Karsdal MA

更新日期：2010-11-10 00:00:00

abstract：BACKGROUND:There is a controversy about the association between vitamin D and cardiovascular diseases (CVDs). The effect of serum 25-OH-vitD on the risk of CVDs was evaluated. METHODS:Major electronic databases including Scopus, Science Direct, and PubMed were searched. All prospective cohort studies on the relationsh...

journal_title：BMC cardiovascular disorders

authors： Gholami F,Moradi G,Zareei B,Rasouli MA,Nikkhoo B,Roshani D,Ghaderi E

更新日期：2019-11-07 00:00:00

abstract：BACKGROUND:High blood glucose impairs voltage-gated K+ (Kv) channel-mediated vasodilation in rat coronary artery smooth muscle cells (CSMCs) via oxidative stress. Advanced glycation end product (AGE) and receptor for AGE (RAGE) axis has been found to impair coronary dilation by reducing Kv channel activity in diabetic ...

journal_title：BMC cardiovascular disorders

authors： Gao S,Hua B,Liu Q,Liu H,Li W,Li H

更新日期：2020-07-14 00:00:00

abstract：BACKGROUND:Candida prosthetic endocarditis is associated with high mortality rates and valve replacement surgery, together with antifungal treatment, play a major role in eradicating the fungal infection. Valve reoperations in these scenarios may be relatively common due to the high infection relapse rates and, in some...

journal_title：BMC cardiovascular disorders

authors： de Santis A,Gilberto GM,Mangini S,Megale AB,Gaiotto FA,Terra RM,Garcia RG

更新日期：2020-10-31 00:00:00

abstract：BACKGROUND:In heart failure (HF) patients with implantable cardioverter defibrillators (ICD) or cardiac resynchronisation therapy defibrillators (CRT-D), remote monitoring has been shown to result in at least non-inferior outcomes relative to in-clinic visits. We aimed to provide further evidence for this effect, and t...

journal_title：BMC cardiovascular disorders

authors： Hansen C,Loges C,Seidl K,Eberhardt F,Tröster H,Petrov K,Grönefeld G,Bramlage P,Birkenhauer F,Weiss C

更新日期：2018-06-28 00:00:00

abstract：BACKGROUND:An unusual case of typical angina which occurred on a long haul flight is presented. This case is notable as this was the index presentation, with no previous symptoms prior to this. Physiological changes at altitude can be marked, and include hypoxia, tachycardia and an increase in cardiac output. These cha...

journal_title：BMC cardiovascular disorders

authors： Al-Janabi F,Mammen R,Karamasis G,Davies J,Keeble T

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:The previous genome-wide studies have shown that rs7193343 single-nucleotide polymorphism (SNP) in zinc finger homeobox 3 (ZFHX3) gene correlate with risk of atrial fibrillation (AF). However, the distribution of this SNP differs significantly among various populations. The present study was to investigate w...

journal_title：BMC cardiovascular disorders

authors： Zhai C,Cong H,Liu Y,Zhang Y,Liu X,Zhang H,Ren Z

更新日期：2015-06-26 00:00:00

abstract：BACKGROUND:Implantation of left atrial appendage (LAA) occlusion devices was shown to be a feasible and effective alternative to oral anticoagulation in patients with non-valvular atrial fibrillation. However, only few data about in-hospital and peri-procedural data are currently available. This study aims to report ab...

journal_title：BMC cardiovascular disorders

authors： Fastner C,Behnes M,Sartorius B,Yildiz M,Mashayekhi K,El-Battrawy I,Lehmann R,Baumann S,Becher T,Borggrefe M,Akin I

更新日期：2016-01-28 00:00:00

abstract：BACKGROUND:The arterial wall possesses several functional and structural properties that define arterial health. Once they become impaired, cardiovascular risk increases. We aimed to ascertain the pattern of correlations among different arterial wall properties and to explore their relations to traditional risk factors...

journal_title：BMC cardiovascular disorders

authors： Lunder M,Janic M,Kejzar N,Sabovic M

更新日期：2012-04-25 00:00:00

abstract：BACKGROUND:Fabry disease (FD) is a hereditary metabolic disorder caused by the partial or total inactivation of a lysosomal hydrolase, the enzyme α-galactosidase A (GLA). This inactivation is responsible for the storage of undegraded glycosphingolipids in the lysosomes with subsequent cellular and microvascular dysfunc...

journal_title：BMC cardiovascular disorders

authors： Pisani A,Imbriaco M,Zizzo C,Albeggiani G,Colomba P,Alessandro R,Iemolo F,Duro G

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:Cardiovascular diseases (CVDs) are one of the leading causes of death and disability in the world. Over 80% of CVD deaths take place in low-and middle-income countries. One-third of the population aged above 40 years suffers from Hypertension (HTN) and this is largely unreported as there is no registry for C...

journal_title：BMC cardiovascular disorders

authors： Khan MA,Javed W,Ahmed M,Walley J,Khan HJ

更新日期：2013-09-25 00:00:00

abstract：BACKGROUND:The ten year probability of cardiovascular events can be calculated, but many people are unaware of their risk and unclear how to reduce it. The aim of this study was to assess whether a community based intervention, for men and women aged between 45 and 64 years without pre-existing coronary heart disease, ...

journal_title：BMC cardiovascular disorders

authors： Richardson G,van Woerden HC,Morgan L,Edwards R,Harries M,Hancock E,Sroczynsk S,Bowley M

更新日期：2008-07-26 00:00:00

abstract：BACKGROUND:Factors affecting heart rate variability (HRV) in patients with atrial septal defect (ASD) have not been clarified. This study sought to identify those factors and establish a preliminary risk model. METHODS:A total of 154 patients with ASD who underwent transcatheter closure and met the study requirements ...

journal_title：BMC cardiovascular disorders

authors： Su Z,Cao Q,Zhang H,Sun W,Zhang H,Sheng Y,Yang R,Kong X

更新日期：2020-09-11 00:00:00