Abstract：
BACKGROUND:This study aimed to determine whether midlife obesity predicts heart failure (HF) over an extended follow-up into old age. METHODS:We studied 7495 men (from a population sample of 9,998 men) without HF, who were 47-55 years old when investigated in 1970 to 1973. All participants were followed up for 35 years, or until death, using the Swedish National Inpatient Register (IPR) and the Cause of Death Register. Over follow-up, 1855 men (24.7%) were discharged from hospital or died with a diagnosis of HF. RESULTS:There was a strong relation between obesity and future risk of HF, which was accentuated over the last years of the long follow-up. After adjusting for age, the risk of HF increased stepwise with increasing body mass index (BMI), even in those with a normal BMI (22.5-24.9) The subdistribution hazard ratio (SHR) was 1.20 (95% CI: 1.02-1.39) in men with a normal BMI, 1.29 (95% CI: 1.11-1.50) for a BMI of 25-27.49, 1.50 (95% CI: 1.27-1.77) for a BMI of 27.5-29.99, and 1.62 (95% CI: 1.33-1.97) for a BMI >30. After adjusting for, age, smoking, occupational class, and physical activity, the results were unchanged. CONCLUSION:Obesity in midlife is strongly related to the long-term risk of developing HF extending into old age where the risk is highest. Even normal body weight (BMI <25) was related to an increased risk of developing HF during life. Because overweight and obesity are largely preventable, our findings further emphasize the importance of public health interventions against the development of obesity.
journal_name
BMC Cardiovasc Disordjournal_title
BMC cardiovascular disordersauthors
Björck L,Novak M,Schaufelberger M,Giang KW,Rosengren Adoi
10.1186/s12872-015-0008-2subject
Has Abstractpub_date
2015-03-10 00:00:00pages
19issn
1471-2261pii
10.1186/s12872-015-0008-2journal_volume
15pub_type
杂志文章abstract：BACKGROUND:The aim was to investigate the extent to which it is possible to diagnose suspected carotid calcification from dental panoramic radiography (PR) and to establish an association to periodontal risk. METHODS:824 PRs from one dental practice were investigated. Parameters considered were gender, age, bone loss ...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-11-67
更新日期：2011-11-09 00:00:00
abstract：BACKGROUND:We assessed the degree to which differences in guideline-based medical therapy for acute myocardial infarction (AMI) contribute to the higher mortality associated with kidney disease. METHODS:In the PREMIER registry, we evaluated patients from 19 US centers surviving AMI. Cox regression evaluated the associ...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,多中心研究
doi：10.1186/1471-2261-9-29
更新日期：2009-07-08 00:00:00
abstract：BACKGROUND:Intermedin (IMD) is involved in the prevention of atherosclerotic plaque progression, possessing cardioprotective effects from hypertrophy, fibrosis and ischemia-reperfusion injury. Elevated plasma IMD levels have been demonstrated in patients with acute coronary syndromes. No human study has examined the ro...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-14-182
更新日期：2014-12-11 00:00:00
abstract：BACKGROUND:Cardio-metabolic syndrome (CMS) is a highly prevalent condition. There is an urgent need to identify effective and integrated multi-disciplinary approaches that can reduce risk factors for CMS. METHODS:Sixty-two patients with a history of CMS were randomized 1:1 into two groups: a standard information -only...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12872-016-0398-9
更新日期：2016-11-18 00:00:00
abstract：BACKGROUND:Timely restoration of bloodflow acute ST-segment elevation myocardial infarction (STEMI) reduces myocardial damage and improves prognosis. The objective of this study was describe the association of demographic factors with hospitalisation rates for STEMI and time to angiography, Percutaneous Coronary Interv...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-020-01487-0
更新日期：2020-05-14 00:00:00
abstract：BACKGROUND:Preoperative low left ventricular ejection fraction (LVEF) has been reported as an independent risk factor for in-hospital mortality. However, there were few studies evaluating the long-term mortality in these patients. We, therefore, conducted this study to investigate long-term outcomes of surgery on patie...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-020-01651-6
更新日期：2020-08-20 00:00:00
abstract：BACKGROUND:The optimal cutoff of the waist-to-hip ratio (WHR) among Han adults in Xinjiang, which is located in the center of Asia, is unknown. We aimed to examine the relationship between different WHRs and cardiovascular risk factors among Han adults in Xinjiang, and determine the optimal cutoff of the WHR. METHODS:...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-14-93
更新日期：2014-07-29 00:00:00
abstract：BACKGROUND:Neointimal formation in atherosclerosis has been subject for intense research. However, good animal models mimicking asymmetrical lesion formation in human subjects have been difficult to establish. The aim of this study was to develop a model which would lead to the formation of eccentric lesions under macr...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-12-91
更新日期：2012-10-17 00:00:00
abstract：BACKGROUND:The association of platelet reactivity and clinical outcomes, especially stent thrombosis, was not so clear. We sought to investigate whether high platelet reactivity affects clinical outcomes of patients with drug eluting stents (DESs) implantation. METHODS:All enrolled individuals treated with DESs implan...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-016-0394-0
更新日期：2016-11-29 00:00:00
abstract：BACKGROUND:Myeloperoxidase (MPO) -containing macrophages and neutrophils have been described at sites of plaque rupture. The presence of these cells in precursor lesions to acute rupture (thin cap atheroma, or vulnerable plaque) and within thrombi adjacent to ruptures has not been described, nor an association with iro...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-9-27
更新日期：2009-06-23 00:00:00
abstract：BACKGROUND:Risk stratification is recommended as the key step to prevent contrast-associated acute kidney injury (CA-AKI) among at-risk patients following coronary angiography (CAG) and/or percutaneous coronary intervention (PCI). Patients with hypoalbuminemia are prone to CA-AKI and do not have their own risk stratifi...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-020-01689-6
更新日期：2020-08-31 00:00:00
abstract：BACKGROUND:In subjects with hypercholesterolaemia, cholesterol values remain above guideline levels. One of the limiting factors to the achievement of goals in such patients is therapeutic non-adherence. The aim of this study is to assess the effectiveness of an intervention designed to improve control of hypercholeste...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,随机对照试验
doi：10.1186/1471-2261-15-8
更新日期：2015-01-19 00:00:00
abstract：BACKGROUND:Ectonucleotidase plays an important role in the regulation of cardiac function by controlling extracellular levels of adenine nucleotides and adenosine. To determine the influence of ischemia-reperfusion injury on ectonucleotidase activity in coronary vascular bed, we compared the metabolic profile of adenin...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-13-53
更新日期：2013-07-28 00:00:00
abstract：BACKGROUND:Patients with rheumatoid arthritis (RA) have an increased risk for cardiovascular disease (CVD) with poor parasympathetic function being implicated as an underlying factor. Factors related to parasympathetic function, commonly assessed by heart rate recovery (HRR) following maximal exercise, are currently no...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-016-0264-9
更新日期：2016-05-10 00:00:00
abstract：BACKGROUND:Aortic intramural hematoma is a life-threatening condition reported with increasing frequency. It can be classified into Stanford type A or B depending on whether the ascending or descending aorta are involved, respectively. However, the onset of acute type A aortic dissection following recovery of type B in...
journal_title：BMC cardiovascular disorders
pub_type：
doi：10.1186/s12872-020-01440-1
更新日期：2020-04-06 00:00:00
abstract：BACKGROUND:The health-related quality of life (HRQOL) of hypertensives may be influenced by blood pressure, adverse effects of drugs used to treat hypertension, or other factors, such as the labelling effect, or beliefs and attitudes about illness and treatment. There is paucity of information on the determinants of HR...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-9-25
更新日期：2009-06-17 00:00:00
abstract：BACKGROUND:Aneurysmal subarachnoid hemorrhage is a life- threatening condition with high rate of disability and mortality. Apolipoprotein E (APOE) and Factor XIIIA (F13A) genes are involved in the pathogenetic mechanism of aneurysmal subarachnoid haemorrhage (aSAH). We evaluated the association of promoter methylation ...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-019-1146-8
更新日期：2019-07-17 00:00:00
abstract：BACKGROUND:Systematic investigation and analysis of cardiovascular health status (CVHS) of Chinese women is rare. This study aimed to assess CVHS and atherosclerotic cardiovascular disease (ASCVD) burden in the Chinese women physicians (CWP) and community-based non-physician cohort (NPC). METHODS:In this prospective, ...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-020-01748-y
更新日期：2020-11-25 00:00:00
abstract：BACKGROUND:Metabolic Syndrome (MetS) and Non-communicable diseases (NCDs) are alarmingly increasing in low-income countries. Yet, very limited is known about the prevalence and risk factors associated with MetS in Ethiopia. METHODS:A cross-sectional study was conducted among adult outpatients (N = 325) at St. Paul's H...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-019-1201-5
更新日期：2019-10-26 00:00:00
abstract：BACKGROUND:Hypertension is a growing public health problem in many developing countries including Ethiopia. However, its prevention and control has not yet received due attention. This study aimed to determine the prevalence and associated factors of hypertension among adults in Gondar city, North-West Ethiopia. METHO...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-12-113
更新日期：2012-11-28 00:00:00
abstract：BACKGROUND:This study aimed at investigating the CV health and CV disease knowledge in terms of LS7 score among 3 age groups in Hong Kong. METHODS:A cross-sectional multicenter observational study was conducted to observe the CV health and disease risk knowledge in Hong Kong. Elderly subjects were recruited from 15 el...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,多中心研究
doi：10.1186/s12872-019-1171-7
更新日期：2019-08-02 00:00:00
abstract：BACKGROUND:Studies regarding the association between prehypertension and the structual changes of left heart are scanty. However, which type of the geometrical change of left heart is predominated one in prehypertension and hypertension is controversial. It is therefore important to investigate geometrical and function...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-016-0286-3
更新日期：2016-05-28 00:00:00
abstract：:After publication of the original article [1], we were notified that the name of the software mentioned in the Background section is TAONET and not Tao Net. ...
journal_title：BMC cardiovascular disorders
pub_type： 已发布勘误
doi：10.1186/s12872-019-1268-z
更新日期：2019-11-26 00:00:00
abstract：BACKGROUND:Left ventricular (LV) rotation is increasingly examined in those with heart disease. The available evidence measuring LV rotation in those with heart diseases has not been systematically reviewed. METHODS:To review systematically the evidence measuring LV rotational changes in various heart diseases compare...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,评审
doi：10.1186/1471-2261-12-46
更新日期：2012-06-24 00:00:00
abstract：BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO). METHODS:The study population included 225 patients, a control group (n = 75), a coronary ...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-14-130
更新日期：2014-09-27 00:00:00
abstract：BACKGROUND:Anomalous aortic origin of the coronary artery (AAOCA) from the opposite sinus of Valsalva with an interarterial course has received much attention due to its association with sudden death in otherwise healthy individuals. AAOCA is relatively common and may have significant public health implications. While ...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,评审
doi：10.1186/1471-2261-12-83
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Coronary artery bypass graft (CABG) surgery is an effective therapeutic strategy for coronary heart disease (CHD). Myocardial longitudinal strain echocardiography with 2D speckle tracking could obtain ventricular function with better accuracy and reliability than the left ventricular ejection fraction. The a...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-019-1162-8
更新日期：2019-08-05 00:00:00
abstract：BACKGROUND:Cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) imaging is increasingly used to assess myocardial involvement in patients with Fabry disease, an X linked lipid storage disorder. However, it is often proposed as an optional tool. A different cardiomyopathic disease progression b...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-14-86
更新日期：2014-07-16 00:00:00
abstract：BACKGROUND:Ideal cardiovascular health (CVH) metrics have been found to be associated with subclinical vascular abnormalities. However, the relationship between ideal CVH metrics and retinal vessel calibers and retinal nerve fiber layer (RNFL) thickness in a Chinese population is unknown. METHODS:We collected informat...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-018-0922-1
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation (AF) is a life-threatening arrhythmia that carries the high risk of thromboembolic complication. Stroke often develops in patients who undergo successful Cox Maze procedure, despite the fact that the procedure has shown a high rate of success in sinus conversion from AF. This study examin...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-14-116
更新日期：2014-09-11 00:00:00
