Abstract：
:We have previously reported on a novel autoantibody in a patient with paraneoplastic sensory-dominant neuropathy. This autoantibody immunostains the rat primary sensory system and reacts with a 47 kDa protein on immunoblotting. Here, we report on the isolation from rat spinal cord of a molecule that is recognized by this autoantibody. By ammonium sulfate cut and gel filtration, affinity and ion exchange chromatographies, the immunoreactive protein was purified to homogeneity and identified as brain-type creatine kinase (B-CK). Our study revealed that the autoantibody of the patient reacted with B-CK in the primary sensory system.
journal_name
Int J Mol Medjournal_title
International journal of molecular medicineauthors
Arawaka S,Daimon M,Sasaki H,Suzuki JI,Kato Tdoi
10.3892/ijmm.1.3.597subject
Has Abstractpub_date
1998-03-01 00:00:00pages
597-600issue
3eissn
1107-3756issn
1791-244Xjournal_volume
1pub_type
杂志文章abstract：:For a number of years, seaweed has been used as a functional food in Asian countries, particularly in Korea, Japan and China. Pyropia yezoensis is a marine red alga that has potentially beneficial biological activities. In this study, we examined the mechanisms through which a Pyropia yezoensis peptide [PYP1 (1-20)] i...
journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
pub_type： 杂志文章
doi：10.3892/ijmm.13.5.623
更新日期：2004-05-01 00:00:00
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更新日期：2000-06-01 00:00:00
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journal_title：International journal of molecular medicine
pub_type： 杂志文章
doi：10.3892/ijmm.2011.612
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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doi：
更新日期：2002-02-01 00:00:00
abstract：:Evodiamine is a botanical alkaloid compound extracted from Tetradium plants. Previous studies have reported that evodiamine (Evo) treatment can reduce food uptake and improve insulin resistance in animals . The skeletal muscle comprises about 40% of the body mass of adults and has a vital role in regulating whole body...
journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
pub_type： 杂志文章
doi：10.3892/ijmm.2.5.545
更新日期：1998-11-01 00:00:00
abstract：:Soy sauce (Shoyu) is a traditional Japanese fermented seasoning and is available worldwide. We investigated the effect of Shoyu polysaccharides (SPS) prepared from soy sauce on the intestinal immune system of mice. SPS enhanced the production of immunoglobulin A (IgA) from Peyer's patch cells in vitro, and its oral ad...
journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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更新日期：2005-09-01 00:00:00
abstract：:Interleukin (IL)‑18, a pro‑inflammatory cytokine, plays an important role in a number of skin diseases. The aim of the present study was to investigate the role of IL‑18 in the development of atopic dermatitis (AD). For this purpose, mice were divided into 4 groups (n=5/group) as follows: i) The wild‑type (WT) control...
journal_title：International journal of molecular medicine
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更新日期：2003-10-01 00:00:00
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
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journal_title：International journal of molecular medicine
pub_type： 杂志文章
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