Should antibiotic treatment of Helicobacter-positive patients with non-ulcer dyspepsia now be recommended?

Abstract:

:Whether cure of Helicobacter pylori infection leads to sustained improvement of non-ulcer dyspepsia (NUD) symptoms is one of the most important unresolved clinical questions in this area. H. pylori has not helped in explaining pathophysiological abnormalities which may cause dyspepsia symptoms. Currently there is insufficient evidence from randomized clinical trials to be sure that cure of H. pylori infection will improve symptoms. There are potential downsides to the widespread use of antibiotics, these include the problem of antibiotic resistance and the possibility of less adequate pH control with acid-suppressive therapy after the infection has been cured.

authors

Veldhuyzen van Zanten SJ,Talley NJ

doi

10.1097/00042737-199805000-00002

subject

Has Abstract

pub_date

1998-05-01 00:00:00

pages

367-70

issue

5

eissn

0954-691X

issn

1473-5687

journal_volume

10

pub_type

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