Abstract:
:Within a cohort of 1022 consecutive singleton births in the Faroe Islands, we assessed prenatal methylmercury exposure from the maternal hair mercury concentration. At approximately 7 years of age, 917 of the children underwent detailed neurobehavioral examination. Little risk is thought to occur as long as the hair mercury concentration in pregnant women is kept below 10-20 microg/g (50-100 nmol/l). A case group of 112 children whose mothers had a hair mercury concentration of 10-20 microg/g was therefore matched to children with exposure below 3 microg/g, using age, sex, time of examination, and the mother's score on Raven's Progressive Matrices as matching criteria. The two groups were almost identical with regard to other factors that might affect neurobehavioral performance in this community. On six neuropsychological test measures, the case group showed mild decrements, relative to controls, especially in the domains of motor function, language, and memory. Subtle effects on brain function therefore seem to be detectable at prenatal methylmercury exposure levels currently considered to be safe.
journal_name
Environ Resjournal_title
Environmental researchauthors
Grandjean P,Weihe P,White RF,Debes Fdoi
10.1006/enrs.1997.3804subject
Has Abstractpub_date
1998-05-01 00:00:00pages
165-72issue
2eissn
0013-9351issn
1096-0953pii
S0013-9351(97)93804-4journal_volume
77pub_type
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