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Synthesis and immobilization of ceramide analogs on silica particles.

Abstract：

:Ceramides are the major lipid components of the stratum corneum, the major permeability barrier of the skin. Here we report a chemical synthesis of ceramide analogs covalently bonded on the silica particles, that can be used to predict the skin permeability of chemicals via HPLC methods.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Yin J,Liu H,Pidgeon C

doi

10.1016/s0960-894x(97)10217-7

subject

Has Abstract

pub_date

1998-01-20 00:00:00

pages

179-82

issue

2

eissn

0960-894X

issn

1464-3405

pii

S0960894X97102177

journal_volume

8

pub_type

杂志文章

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