Tuberous sclerosis complex and Wolff-Parkinson-White syndrome.

Abstract:

:This report highlights the association between tuberous sclerosis and Wolff-Parkinson-White syndrome. Ten patients with concurrent diagnoses of Wolff-Parkinson-White syndrome and tuberous sclerosis were identified. Wolff-Parkinson-White syndrome presented early in life, nine cases being diagnosed in the first year. Eight of the 10 cases were male. In eight cases, the syndrome was associated with supraventricular tachycardias, and in nine with cardiac rhabdomyomata. One child died from cardiac failure secondary to obstruction of the left ventricular outflow tract by a rhabdomyoma. Five of nine survivors showed resolution of Wolff-Parkinson-White syndrome on follow up. The accessory pathway was localised in nine patients from surface electrocardiograms: six children had left sided pathways and three had right sided pathways.

journal_name

Arch Dis Child

authors

O'Callaghan FJ,Clarke AC,Joffe H,Keeton B,Martin R,Salmon A,Thomas RD,Osborne JP

doi

10.1136/adc.78.2.159

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

159-62

issue

2

eissn

0003-9888

issn

1468-2044

journal_volume

78

pub_type

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