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Alpha-interferon and isoprinosine in adult-onset subacute sclerosing panencephalitis.

Abstract：

:We report eight patients with adult-onset subacute sclerosing panencephalitis (SSPE), of which, four were treated with oral isoprinosine and four with intraventricular alpha-interferon plus oral isoprinosine. One of the four patients treated with oral isoprinosine died within two months, and the disease progressed in three patients. Of the four patients treated with oral isoprinosine plus intraventricular alpha-interferon, one showed mild progression, one remission, and the remaining two showed stabilization. The group of patients is relatively small, but our results suggest that treatment with oral isoprinosine plus alpha-interferon is effective for SSPE.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Gokcil Z,Odabasi Z,Demirkaya S,Eroglu E,Vural O

doi

10.1016/s0022-510x(98)00302-5

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

62-4

issue

1

eissn

0022-510X

issn

1878-5883

pii

S0022510X98003025

journal_volume

162

pub_type

临床试验,杂志文章

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