Abstract:
:Malignant melanoma, the least common but most serious form of skin cancer, is increasing at a faster rate than any other form of cancer. Early diagnosis can lead to cures through surgery alone. Patients with deeper primary lesions (greater than 4 mm) or regional lymph node involvement have a high risk of relapse. High-dose alpha interferon-2b is the first agent to significantly affect the relapse-free survival of high-risk patients with melanoma in a large randomized, controlled trial. Knowledge of the stages of malignant melanoma, its treatments, the mechanism of action of interferon, and commonly experienced adverse events will contribute to the nurse's ability to manage the clinical problems patients with melanoma face.
journal_name
Clin J Oncol Nursjournal_title
Clinical journal of oncology nursingauthors
Gale DM,Kiley KEsubject
Has Abstractpub_date
1998-01-01 00:00:00pages
5-10issue
1eissn
1092-1095issn
1538-067Xjournal_volume
2pub_type
杂志文章,评审abstract::Gastrointestinal stromal tumor (GIST), a form of soft-tissue sarcoma, is the most common noncarcinomatous tumor of the gastrointestinal tract. Despite its high incidence of recurrence, the malignant potential of GIST has been under-recognized. Advances in diagnostic technology since 2000 have led to increased diagnose...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/05.CJON.161-169
更新日期:2005-04-01 00:00:00
abstract::Neuroendocrine tumors (NETs), including gastroenteropancreatic NETs, or GEP-NETs, are heterogenous tumors that arise from diffuse neuroendocrine cells and other organs, such as the lung, ovary, and thyroid. Lutetium Lu 177 dotatate (Lutathera®) is a newly approved targeted therapy for patients with advanced GEP-NETs. ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/18.CJON.565-568
更新日期:2018-10-01 00:00:00
abstract::First-line treatment for chronic myelogenous leukemia (CML) is imatinib, but some patients do not respond or develop resistance to the drug, leading to suboptimal responses. Dasatinib and nilotinib are approved second-line compounds for patients experiencing imatinib failure. In a prospective comparison of dasatinib w...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/09.CJON.537-542
更新日期:2009-10-01 00:00:00
abstract::The COVID-19 pandemic has required us to recognize a new normal and other additions to our general and clinical vocabulary. Some were preexisting terms that now have been broadened or changed during these unprecedented times. Others have helped to bring to light some of the issues or difficulties that healthcare profe...
journal_title:Clinical journal of oncology nursing
pub_type: 社论
doi:10.1188/20.CJON.223
更新日期:2020-06-01 00:00:00
abstract::Genetic testing for hereditary cancer syndromes is an integral component of oncology care. Various types of common errors that occur in the genetic testing process are presented in this article with actual clinical case examples and commentary. Genetic errors are expensive and may result in poor outcomes for the patie...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.673-676
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Hematopoietic stem cell transplantation (HCT) is a complicated treatment modality used to address hematologic malignancies and other disorders. The complex care of patients undergoing HCT places them at high risk for poor outcomes during times of transition. Education is a critical component of preparing pat...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/15.CJON.E74-E79
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Women who have been identified with a BRCA mutation benefit from a multidisciplinary, individualized medical evaluation to reduce their risk of developing cancers. Identifying women who would gain from testing for BRCA mutations is essential. Nurse practitioners (NPs) as primary care providers are important ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/16.CJON.327-331
更新日期:2016-06-01 00:00:00
abstract::Treatment with the humanized monoclonal antibody trastuzumab can significantly improve outcomes for patients with early or metastatic HER2-positive breast cancer. In a small proportion of patients, trastuzumab is associated with an increased risk of cardiac dysfunction. Although the mechanisms have yet to be fully est...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/10.CJON.630-640
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:A cancer diagnosis is a serious stressor that is associated with anxiety, depression, sleep disorders, and inability to fulfill daily routines. Many pharmacologic and nonpharmacologic options are available to help patients with cancer manage anxiety. OBJECTIVES:This randomized, controlled trial examined the...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,随机对照试验
doi:10.1188/18.CJON.203-210
更新日期:2018-04-01 00:00:00
abstract::Chronic lymphocytic leukemia (CLL) is the most commonly diagnosed form of leukemia in the Western world, accounting for approximately 20%-30% of all cases of leukemia. Despite recent medical and scientific advances, the literature on the subjective experience and nursing care of patients diagnosed with CLL remains sca...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/08.CJON.417-423
更新日期:2008-06-01 00:00:00
abstract::Many hospitalized patients with cancer are malnourished. Some become critically ill and experience delayed wound healing, loss of muscle strength, and reduced infection fighting ability as a consequence of the loss of nutritional reserves. Complications of critical illness may cause interruption in normal gastrointest...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/02.CJON.287-289
更新日期:2002-09-01 00:00:00
abstract::Today, I am writing for the first time as the new editor of the Clinical Journal of Oncology Nursing (CJON). It is my honor to assume this role from my colleague and mentor, Deborah K. Mayer, PhD, RN, AOCN, FAAN. For eight years, Deb served as the editor of one of the most widely read journals in oncology nursing, CJO...
journal_title:Clinical journal of oncology nursing
pub_type: 社论
doi:10.1188/15.CJON.387
更新日期:2015-08-01 00:00:00
abstract::An intervention with the Scored Patient-Generated Subjective Global Assessment was implemented at a community cancer center to identify patients with sarcoma at risk for malnutrition. This population usually is not considered to be at nutritional risk because of young age and the site of diagnosis; however, 60% of pat...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/10.CJON.375-377
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:In the management of lung cancer, molecular profiling of the tumor is pivotal to defining a personalized treatment plan and is recommended for each patient. OBJECTIVES:The purpose of this article is to provide an update on genomic testing in lung cancer and the associated targeted treatment options. In addi...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.648-656
更新日期:2020-12-01 00:00:00
abstract::Although uncommon, 5-fluorouracil (5-FU) infiltrations do occur. Two case studies involving 5-FU infiltration from totally implanted venous access devices identified at the conclusion of a 46-hour continuous infusion via an ambulatory infusion pump are presented. These cases highlight the importance of patient and car...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/19.CJON.537-539
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Early childhood dental caries (dental cavities) is an infectious process. The development of oral problems during cancer care results in pain, fever, and delay in treatment. . OBJECTIVES:The objective of this project was to integrate preventive oral care into pediatric oncology care. . METHODS:This proje...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/17.CJON.611-616
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Patients with cancer often experience prominent deficiencies in cancer care in the immediate period following initial cancer diagnosis. OBJECTIVES:This article aims to determine whether the inclusion of a gastrointestinal (GI) oncology nurse navigator (ONN) on the multidisciplinary cancer care team is assoc...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/18.CJON.E141-E145
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The concept of transitional care and the methods and processes to efficiently and effectively transition patients between a variety of care settings remains a continuous healthcare goal. Despite the numerous transitional care models that have been developed and implemented in a myriad of healthcare settings,...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/18.CJON.S2.37-41
更新日期:2018-12-01 00:00:00
abstract::My personal experience with nursing school can be best described as floating in the middle of the ocean with a life vest while kicking and paddling to keep my head above the water. I spent countless hours studying for examinations, rewriting care plans, and practicing skills. In addition to my own efforts to survive, ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.455
更新日期:2020-08-01 00:00:00
abstract::The BCR-ABL inhibitor imatinib is standard first-line therapy for patients with chronic myeloid leukemia (CML) and has revolutionized treatment of the disease. However, resistance and intolerance to the agent have emerged as major clinical complications. Dasatinib is the first and only dual BCR-ABL/SRC family kinase i...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/09.CJON.316-323
更新日期:2009-06-01 00:00:00
abstract::This study examined the value and effectiveness of a patient navigation program in terms of timeliness of access to cancer care, resolution of barriers, and satisfaction in 55 patients over a six-month period. Although not statistically significant, the time interval between diagnostic biopsy to first consultation wit...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/11.CJON.41-48
更新日期:2011-02-01 00:00:00
abstract::Providing care for patients with cancer places caregivers at risk for experiencing elevated levels of stress. Caregivers of patients with brain tumors may be at increased risk because of the multifaceted needs of this patient population. As such, the authors sought to determine caregiver preferences toward various typ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/07.CJON.723-727
更新日期:2007-10-01 00:00:00
abstract::The goal of achieving maximum productivity through process redesign and teamwork in oncology laboratory (lab) operations can be challenging in cancer care organizations. At an urban cancer center, missing lab orders occurred frequently and led to increases in lab errors, turnaround time, and patient wait times. Patien...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/20.CJON.571-574
更新日期:2020-10-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) ranks as the eighth most common cancer in the world. Although uncommon in North America, the incidence of HCC in the United States has increased by 70% since the 1980s (Yu, Yuan, Govindarajan, & Ross, 2000). The most frequent causes of malignant hepatic disease in the United States are m...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/03.CJON.647-652
更新日期:2003-11-01 00:00:00
abstract::Radioimmunotherapy is a new cancer therapy that combines the cytotoxicity of radiation with the tumor-specific targeting of monoclonal antibodies. Yttrium 90 (Y-90) ibritumomab tiuxetan (Zevalin, IDEC Pharmaceuticals Corporation, San Diego, CA) is indicated for the treatment of patients with relapsed or refractory low...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/04.CJON.31-34
更新日期:2004-02-01 00:00:00
abstract::Increased understanding of the molecular composition of breast cancer tumors has led to the development of targeted anticancer agents. Novel therapies directed against human epidermal growth factor receptor 2 (HER2) in breast cancer have been developed. One such agent, trastuzumab emtansine (T-DM1), is an antibody dru...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章
doi:10.1188/13.CJON.E58-E62
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Since the completion of the Human Genome Project in 2003, the implications of genetics and genomics for health and illness have become clearer. All nurses, at all levels and across all specialties, must have a basic understanding of genetics and genomics to provide appropriate care. . OBJECTIVES:This artic...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/17.CJON.747-753
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Cervical cancer is the fourth most common cancer among women worldwide. Most diagnoses occur in developing countries where cases are detected in later stages with poorer prognoses. Cervical cancer is a preventable disease; however, most women in developing and resource-limited countries do not have the acces...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/16.CJON.79-83
更新日期:2016-02-01 00:00:00
abstract::Selection of letters to be published is the decision of the editor. For acceptance, letters must be signed. A letter can appear anonymously if requested by the author. All letters are subject to editing. A letter that questions, criticizes, or responds to a previously published Clinical Journal of Oncology Nursing art...
journal_title:Clinical journal of oncology nursing
pub_type: 信件
doi:10.1188/14.CJON.14-15
更新日期:2014-02-01 00:00:00
abstract::Approximately 11,000 Americans will be diagnosed with acute myeloid leukemia (AML) in 2003, and about 75% ultimately will die from the disease. Despite significant advances in understanding biologic, molecular, and cytogenetic aspects of this malignancy, several other areas remain poorly understood. During the 1990s, ...
journal_title:Clinical journal of oncology nursing
pub_type: 杂志文章,评审
doi:10.1188/03.CJON.535-540
更新日期:2003-09-01 00:00:00