当前位置： SCI文献检索 > JOURNAL OF CLINICAL EPIDEMIOLOGY期刊下所有文献 > One-hour postload plasma glucose and risks of fatal coronary heart disease and stroke among nondiabetic men and women: the Chicago Heart Association Detection Project in Industry (CHA) Study.

One-hour postload plasma glucose and risks of fatal coronary heart disease and stroke among nondiabetic men and women: the Chicago Heart Association Detection Project in Industry (CHA) Study.

Abstract：

:Associations of baseline one-hour postload plasma glucose with 22-year coronary heart disease, stroke, cardiovascular diseases, and all cause mortality were assessed in five age-specific cohorts of nondiabetic men and women from the Chicago Heart Association Detection Project in Industry: 10,269 men ages 18-39 years; 7993 men ages 40-59 years; 1240 men ages 60-74 years; 6319 women ages 40-59 years; and 932 women ages 60-74 years. Plasma glucose was determined one hour after a 50-gram oral glucose load. Cox regression analyses were used to control for age and other covariates. Generally, higher glucose was significantly associated with mortality from coronary heart disease, stroke, cardiovascular diseases, and all cause mortality in men and women. This large longitudinal study provides evidence that one-hour postload plasma glucose in the absence of clinical diabetes at baseline apparently is an independent risk factor for fatal coronary heart disease and stroke in middle-aged and older nondiabetic men and women, and also for cardiovascular diseases and for all cause mortality.

journal_name

J Clin Epidemiol

journal_title

Journal of clinical epidemiology

authors

Orencia AJ,Daviglus ML,Dyer AR,Walsh M,Greenland P,Stamler J

doi

10.1016/s0895-4356(97)00201-1

subject

Has Abstract

pub_date

1997-12-01 00:00:00

pages

1369-76

issue

12

eissn

0895-4356

issn

1878-5921

pii

S0895435697002011

journal_volume

50

pub_type

杂志文章

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