Inhibition of spontaneous contractility of the human and the rabbit fallopian tube by potassium.

Abstract:

:Spontaneous contractions of circular and longitudal muscle of the ampulla and isthmus of human and rabbit Fallopian tubes were recorded isometrically. Addition of K+ to tissue in K+-free medium always caused immediate inhibition of spontaneous contractility. K+-induced inhibition was prevented by ouabain and reversed by removal of K+. It is suggested that K+ caused inhibition of contractility by activating electrogenic Na+ pumping with resultant hyperpolarization of the muscle cells.

journal_name

Am J Obstet Gynecol

authors

Johns A,Molnar S,Paton DM

doi

10.1016/0002-9378(76)90178-2

subject

Has Abstract

pub_date

1976-03-01 00:00:00

pages

506-9

issue

5

eissn

0002-9378

issn

1097-6868

pii

0002-9378(76)90178-2

journal_volume

124

pub_type

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