Lymphoepithelial cyst (LEC) of the pancreas: cytomorphology and differential diagnosis on fine-needle aspiration (FNA).

Abstract:

:Lymphoepithelial cyst (LEC) of the pancreas is an extremely rare benign entity. We describe the cytopathologic findings of such a lesion in a 49-yr-old woman who was examined for epigastric pain. A trans-esophageal ultrasound-guided fine-needle aspiration of a pancreatic mass disclosed an intimate mixture of squamous epithelial cells and small, mature lymphocytes in a background of keratinaceous debris, anucleate squames, and multinucleated histiocytes. On histopathologic examination, a subsequent resection showed a multiloculated cystic lesion with a stratified squamous epithelial lining surrounded by well-formed lymphoid tissue, suggestive of LEC. The differential diagnosis includes other pancreatic pseudocysts, dermoid cyst, mucinous cystic neoplasms, adenosquamous carcinoma, and metastatic squamous cell carcinoma.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Mandavilli SR,Port J,Ali SZ

doi

10.1002/(sici)1097-0339(199906)20:6<371::aid-dc8>3

subject

Has Abstract

pub_date

1999-06-01 00:00:00

pages

371-4

issue

6

eissn

8755-1039

issn

1097-0339

pii

10.1002/(SICI)1097-0339(199906)20:6<371::AID-DC8>3

journal_volume

20

pub_type

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