An in vitro comparison of three fluoride regimens on enamel remineralization.

Abstract:

:The purpose of this study was to compare the enamel remineralization effectiveness of a fluoride rinse, fluoridated dentifrice, and fluoride-releasing restorative material. Forty extracted molars had 1 x 5 mm artificial carious lesions formed at the interproximal contact point. One-hundred-micrometer sections were obtained at the caries sites, and polarized light photomicrographs were obtained. The sections had varnish placed, leaving only the external section site exposed, and were situated back into the original tooth. Forty other molars were obtained; 10 had Class-II glass ionomer cement restorations placed. These 40 teeth were mounted to have interproximal contact with the adjacent teeth containing artificial carious lesions. Specimens were placed in closed environments of artificial saliva for 1 month, with saliva being changed every 48 h. Ten specimen pairs were brushed with a fluoridated dentifrice for 2 min, twice per day, 10 specimen pairs were rinsed with a 0.05% sodium fluoride rinse for 1 min twice per day, 10 specimen pairs had Class-II glass ionomer cement restorations positioned adjacent to 10 teeth with artificial carious lesions, and 10 specimen pairs acted as controls. After 30 days, the same sections were photographed again under polarized light, and areas of the lesions were digitized quantitatively. Results demonstrated the mean (+/- SD) remineralization (mu m2) in Thoulet's 1.41 imbibition media to be: lesions adjacent to glass ionomer cement restorations, 2.45 +/- 170; lesions exposed to a fluoridated dentifrice, 223 +/- 102; lesions exposed to 0.05% sodium fluoride rinse, 374 +/- 120, and control lesions only exposed to artificial saliva, 101 +/- 69. Duncan's analysis indicated the fluoridated rinse to have significantly greater remineralization effects on adjacent caries than the other groups (p < or = 0.05). The glass ionomer restorative material and fluoridated dentifrice also had significantly greater remineralization effects on adjacent caries than the control, yet significantly less than the fluoridated rinse (p < or = 0.05).

journal_name

Caries Res

journal_title

Caries research

authors

Marinelli CB,Donly KJ,Wefel JS,Jakobsen JR,Denehy GE

doi

10.1159/000262432

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

418-22

issue

6

eissn

0008-6568

issn

1421-976X

journal_volume

31

pub_type

杂志文章
  • Caries prevalence after cessation of water fluoridation in La Salud, Cuba.

    abstract::In the past, caries has usually increased after cessation of water fluoridation. More recently an opposite trend could be observed: DMFT remaining stable or even decreasing further. The aim of the present study conducted in La Salud (Province of Habana) in March 1997 was to analyse the current caries trend under the s...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000016565

    authors: Künzel W,Fischer T

    更新日期:2000-01-01 00:00:00

  • Effect of different fluoride levels in dentifrice on the development of approximal caries.

    abstract::The development of approximal carious lesions was monitored on annual bite-wing radiographs obtained from 315 children, participating in a controlled dentifrice trial; 157 of these children had used a dentifrice containing 250 ppm F and 158 a dentifrice containing 1,000 ppm F (both as NaF) during a 3-year period as th...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261369

    authors: Bjarnason S,Finnbogason SY

    更新日期:1991-01-01 00:00:00

  • The Impact of the Demineralized Organic Matrix on the Effect of TiF4 Varnish on the Progression of Dentin Erosive Loss.

    abstract::This in vitro study compared the effect of TiF4 varnish with that of NaF varnish, applied on pre-eroded bovine dentin samples, with respect to the progression of erosive loss, in the presence or absence of the demineralized organic matrix (DOM). One hundred and sixty bovine dentin samples were pre-eroded (0.1% citric ...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000475534

    authors: Martines de Souza B,Vertuan M,Buzalaf MAR,Magalhães AC

    更新日期:2017-01-01 00:00:00

  • Do Patients with Extrinsic Black Tooth Stains Have a Lower Dental Caries Experience? A Systematic Review and Meta-Analysis.

    abstract::Studies have suggested that individuals affected by extrinsic black tooth stains have less dental caries experience in comparison to those without this condition. The aim of the present study was to perform a systematic review and meta-analysis to determine whether there is scientific evidence demonstrating that extri...

    journal_title:Caries research

    pub_type: 杂志文章,meta分析

    doi:10.1159/000500476

    authors: de Rezende VS,Fonseca-Silva T,Drumond CL,Ramos-Jorge ML,Paiva SM,Vieira-Andrade RG

    更新日期:2019-01-01 00:00:00

  • Partial removal of carious dentine: a multicenter randomized controlled trial and 18-month follow-up results.

    abstract:AIM:The aim of this study was to evaluate the effectiveness of partial removal of carious dentine and restoration in a single session (PDR) and stepwise excavation (SW), both of which are treatments for deep carious lesions, in Public Health Services in Brazil. METHODS: INCLUSION CRITERIA:patients ≥6 years old, perma...

    journal_title:Caries research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1159/000344013

    authors: Maltz M,Jardim JJ,Mestrinho HD,Yamaguti PM,Podestá K,Moura MS,de Paula LM

    更新日期:2013-01-01 00:00:00

  • Secondary Caries Development in in situ Gaps next to Composite and Amalgam.

    abstract::This in situ study investigated the secondary caries development in dentin in gaps next to composite and amalgam. For 21 days, 14 volunteers wore a modified occlusal splint containing human dentin samples with an average gap of 215 µm (SD=55 µm) restored with three different materials: Filtek Supreme composite, Clearf...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000438728

    authors: Kuper NK,Montagner AF,van de Sande FH,Bronkhorst EM,Opdam NJ,Huysmans MC

    更新日期:2015-01-01 00:00:00

  • Influence of salivary macromolecules and fluoride on enamel lesion remineralization in vitro.

    abstract::The aim of this study was to investigate the influence of salivary macromolecules on enamel lesion remineralization in the presence or absence of fluoride. Paraffin-stimulated whole saliva was centrifuged, and the supernatant was dialyzed in 1,000 molecular-weight cutoff dialysis tubes, first against a phosphate buffe...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000111748

    authors: Fujikawa H,Matsuyama K,Uchiyama A,Nakashima S,Ujiie T

    更新日期:2008-01-01 00:00:00

  • Detection of approximal caries in 5-year-old Swedish children.

    abstract::The aim was to assess how accurately some commonly used risk factors/risk markers (predictors) for caries development could identify children with and without approximal caries as judged from bitewing radiography. Two hundred and sixty-seven consecutive 5-year-old children from two Swedish cities participated. Three e...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000083153

    authors: Anderson M,Stecksén-Blicks C,Stenlund H,Ranggård L,Tsilingaridis G,Mejàre I

    更新日期:2005-03-01 00:00:00

  • Caries-preventive effect of fluoride varnish with different fluoride concentrations.

    abstract::Based on the current concept of the caries-preventive mechanism of fluoride, the fluoride concentration of some professionally applied fluoride preparations appears unnecessarily high. The aim of this trial was to study whether reducing the fluoride concentration of the sodium fluoride varnish Duraphat from the presen...

    journal_title:Caries research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000261623

    authors: Seppä L,Pöllänen L,Hausen H

    更新日期:1994-01-01 00:00:00

  • In vitro remineralization of caries lesions treated with surface-active phosphates.

    abstract::Intact human enamel was demineralized in vitro to obtain artificial caries lesions. Part of the lesions was then treated with different surface-active compounds and remineralized with a remineralizing solution. The other part of the lesions was de- and remineralized in the same way, but was not treated with a surface-...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261339

    authors: Borggreven JM,Lammers PC,Hoeks T,Zwanenburg B,Driessens FC

    更新日期:1991-01-01 00:00:00

  • Clinical diagnosis of occlusal dentin caries.

    abstract::An occlusal restoration is usually considered necessary when a lesion extends into the dentin. This study aimed to assess the relationship between the clinical appearance of occlusal caries and the lesion depth. Special attention was paid to differentiate the inner, partly demineralitzed layer of carious dentin that s...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000262003

    authors: Tveit AB,Espelid I,Fjelltveit A

    更新日期:1994-01-01 00:00:00

  • Identification of Caries Risk Determinants in Toddlers: Results of the GUSTO Birth Cohort Study.

    abstract::The aim of this study was to identify risk determinants leading to early childhood caries (ECC) and visible plaque (VP) in toddlers. Data for mother-child pairs participating in the Growing Up in Singapore towards Healthy Outcomes (GUSTO) birth cohort were collected from pregnancy to toddlerhood. Oral examinations wer...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000471811

    authors: Un Lam C,Khin LW,Kalhan AC,Yee R,Lee YS,Chong MF,Kwek K,Saw SM,Godfrey K,Chong YS,Hsu CY

    更新日期:2017-01-01 00:00:00

  • A competing risk survival analysis model to assess the efficacy of filling carious primary teeth.

    abstract::In recent years a strategy of selective, symptom-based intervention of carious primary teeth has been developed amongst some British general dental practitioners. Practice-based studies appear to provide evidence that policies of restoration of symptomless carious primary teeth do not confer any significant benefits a...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000314677

    authors: Stephenson J,Chadwick BL,Playle RA,Treasure ET

    更新日期:2010-01-01 00:00:00

  • Synergistic inhibitory effect of cationic peptides and antimicrobial agents on the growth of oral streptococci.

    abstract::Although chlorhexidine is one of the most efficacious antimicrobial agents used for the prevention of dental caries, side effects limit its application. The effects of gaegurin 6 (GGN6), an animal-derived cationic peptide, and its derivatives PTP6 and PTP12 on the growth of oral streptococci were investigated to asses...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000073394

    authors: Kim SS,Kim S,Kim E,Hyun B,Kim KK,Lee BJ

    更新日期:2003-11-01 00:00:00

  • Fluoride uptake in human teeth from fluoride-releasing restorative material in vivo and in vitro: two-dimensional mapping by EPMA-WDX.

    abstract::Class V cavities were prepared in the upper and lower left second premolars from an individual under infiltration anesthesia. The cavities were filled with fluoride- releasing resin (TF). One month later, the teeth were extracted. As a control (in vitro), the upper and lower right second premolars were extracted at th...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000047441

    authors: Yamamoto H,Iwami Y,Unezaki T,Tomii Y,Ebisu S

    更新日期:2001-03-01 00:00:00

  • Caries incidence and lesion progression from adolescence to young adulthood: a prospective 15-year cohort study in Sweden.

    abstract::The objectives were (1) to assess caries development, including the incidence and rate of lesion progression, in a Swedish cohort from adolescence to young adulthood and (2) to compare the caries incidence rates in adolescents with those of young adults. The original material consisted of 536 children aged 11-13 years...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000075937

    authors: Mejàre I,Stenlund H,Zelezny-Holmlund C

    更新日期:2004-03-01 00:00:00

  • The influence of enamel defects on the development of early childhood caries in a population with low socioeconomic status: a longitudinal study.

    abstract::The purpose of this study was to evaluate the influence of enamel defects in the development of dental caries and their association with feeding practices and oral health behaviors in a cohort study of low-socioeconomic children from birth to 36 months of age in northeastern Brazil. Subjects were registered at birth a...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000093188

    authors: Oliveira AF,Chaves AM,Rosenblatt A

    更新日期:2006-01-01 00:00:00

  • The effect of chlorhexidine/xylitol chewing-gum on cariogenic salivary microflora: a clinical trial in elderly patients.

    abstract::The effects of 14-day use of either a chlorhexidine/xylitol or a xylitol chewing gum on salivary levels of mutans streptococci, lactobacilli, and yeasts were determined for 53 subjects (mean age 79.49 +/- 7.7 years) participating in this randomised, double-blind, placebo-controlled trial. Salivary flow rates and ename...

    journal_title:Caries research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000262382

    authors: Simons D,Kidd EA,Beighton D,Jones B

    更新日期:1997-01-01 00:00:00

  • Deposition of fluoride on tooth surfaces by a two-solution mouthrinse in vitro.

    abstract::A constant-composition fluoride (F) titration method was used to measure the amount of leachable F deposited on tooth surfaces in vitro by a 1-min rinse with a 228-ppm F solution (12 mmol/l sodium fluoride). The mean F uptake was 0.23 +/- (SE) 0.07 microgram/cm2, corresponding to less than 0.2% of the F contained in t...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261400

    authors: Chow LC,Takagi S

    更新日期:1991-01-01 00:00:00

  • Evaluation of Fluorescence Imaging with Reflectance Enhancement (FIRE) for Quantifying Enamel Demineralization In vitro.

    abstract:OBJECTIVES:To assess the ability of fluorescence imaging with reflectance enhancement (FIRE) to quantify early enamel demineralization in vitro. METHODS:A total of 30 bovine enamel specimens were immersed in demineralizing solution to produce artificial caries. Specimens were examined by FIRE, quantitative light-induc...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000365298

    authors: Xiao Q,Tu R,He T,Yin W,Li X,Hu D,Zhang X

    更新日期:2015-01-01 00:00:00

  • A light microscopic study of odontoblastic and non-odontoblastic cells involved in tertiary dentinogenesis in well-defined cavitated carious lesions.

    abstract::This study examines cellular and microradiographic findings in thin, undemineralized sections of 46 cavitated lesions, that were clinically well-defined with respect to lesion activity and estimated lesion age at extraction time. The progressive stages of surface breakdown ranged from enamel cavitation to larger denti...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000016495

    authors: Bjørndal L,Darvann T

    更新日期:1999-01-01 00:00:00

  • The influence of mineral loss on the auto-fluorescent behaviour of in vitro demineralised dentine.

    abstract::The aim of this study is to investigate the influence of demineralisation on the fluorescent properties of dentine. The fluorescence emission at 529 nm due to 515 nm excitation of in vitro demineralised lesions was determined with a micro-Raman spectroscope as a function of location. Results were compared with the min...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000262143

    authors: van der Veen MH,ten Bosch JJ

    更新日期:1996-01-01 00:00:00

  • Gastro-oesophageal reflux disease symptoms and tooth wear in patients with Sjögren's syndrome.

    abstract::The aim of this study was to assess the prevalence of gastro-oesophageal reflux disease (GORD) symptoms and tooth wear in patients with Sjögren's syndrome (SS) compared with matched controls. GORD symptoms were assessed for 33 SS patients and 20 age- and sex-matched controls. Tooth wear was assessed in all patients an...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000329381

    authors: Wan Nik WN,Banerjee A,Moazzez R

    更新日期:2011-01-01 00:00:00

  • Methods of projecting long-term relative efficacy of products exhibiting small short-term efficacy.

    abstract::There is ample evidence that caries can develop well into the middle-aged years, and for many subjects, for most of their adult lives. The kinds of benefits to expect for adults in the longer term for improved fluoride products, especially dentifrices, based upon small observed relative improvements in short-term effi...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261561

    authors: Kingman A

    更新日期:1993-01-01 00:00:00

  • What is the optimum fluoride concentration needed for the remineralization process?

    abstract::In vitro experiments could demonstrate that only negligible amounts of fluoride are necessary to promote remineralization of incipient caries lesions. From the clinical point of view, there is evidence that only under certain circumstances is a stabilization of the surface zone of an incipient caries lesion the true m...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000049112

    authors: Hellwig E,Lussi A

    更新日期:2001-01-01 00:00:00

  • Effects of lactate dehydrogenase on fissure caries in rats.

    abstract::The effect of supplementing the diet or drinking water with lactate dehydrogenase (LDH) on the formation of caries lesions in rats was investigated. Addition of LDH [20 and 5 mg/kg in the high-sucrose (65%) diet, 2 and 1 U/ml in the drinking water (LDH-specific activity 735 U/mg solid)] resulted in significant reducti...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261236

    authors: Higham SM,Edgar WM

    更新日期:1990-01-01 00:00:00

  • Interactions of zinc with fluoride on growth, glycolysis and survival of Streptococcus mutans GS-5.

    abstract::Effects of zinc and/or fluoride on growth, glycolysis and survival of Streptococcus mutans GS-5 were examined in vitro. Zinc inhibited growth and glycolysis, and enhanced the antimetabolic activity of fluoride. Zinc alone had little effect on cell survival. During cell growth without pH control a protection from cell ...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000261149

    authors: Izaguirre-Fernández EJ,Eisenberg AD,Curzon ME

    更新日期:1989-01-01 00:00:00

  • The remineralization of EDTA-treated human dentine.

    abstract::The remineralization of whole human dentine treated with a neutral EDTA solution was investigated: the treatment periods were 15, 30 and 120 min. From the literature it is known that EDTA removes noncollagenous proteins (NCPs) from dentine powders. In order to extract more phosphoproteins from dentine lesions, in part...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000016529

    authors: Kawasaki K,Ruben J,Stokroos I,Takagi O,Arends J

    更新日期:1999-07-01 00:00:00

  • The effect of adding calcium lactate to xylitol chewing gum on remineralization of enamel lesions.

    abstract::The purpose of the study was to determine whether adding calcium lactate to chewing gum containing xylitol enhances remineralization of enamel surfaces using an early caries lesion model. Enamel slabs were cut from human extracted sound teeth and artificial subsurface lesions created within each. Half the enamel slabs...

    journal_title:Caries research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000088905

    authors: Suda R,Suzuki T,Takiguchi R,Egawa K,Sano T,Hasegawa K

    更新日期:2006-01-01 00:00:00

  • Chitosan nanoparticles affect the acid tolerance response in adhered cells of Streptococcus mutans.

    abstract::In this study we evaluated the effect of chitosan nanoparticles on the acid tolerance response (ATR) of adhered Streptococcus mutans. An ATR was induced by exposing S. mutans to pH 5.5 for 2 h and confirmed by exposing the acid-adapted cells to pH 3.5 for 30 min, with the majority of cells appearing viable according t...

    journal_title:Caries research

    pub_type: 杂志文章

    doi:10.1159/000331206

    authors: Neilands J,Sutherland D,Resin A,Wejse PL,Chávez de Paz LE

    更新日期:2011-01-01 00:00:00