Abstract:
:In this study we evaluated the effect of chitosan nanoparticles on the acid tolerance response (ATR) of adhered Streptococcus mutans. An ATR was induced by exposing S. mutans to pH 5.5 for 2 h and confirmed by exposing the acid-adapted cells to pH 3.5 for 30 min, with the majority of cells appearing viable according to the LIVE/DEAD® technique. However, when chitosan nanoparticles were present during the exposure to pH 5.5, no ATR occurred as most cells appeared dead after the pH 3.5 shock. We conclude that the chitosan nanoparticles tested had the ability to hinder ATR induction in adhered S. mutans.
journal_name
Caries Resjournal_title
Caries researchauthors
Neilands J,Sutherland D,Resin A,Wejse PL,Chávez de Paz LEdoi
10.1159/000331206subject
Has Abstractpub_date
2011-01-01 00:00:00pages
501-5issue
6eissn
0008-6568issn
1421-976Xpii
000331206journal_volume
45pub_type
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