Chitosan nanoparticles affect the acid tolerance response in adhered cells of Streptococcus mutans.

Abstract:

:In this study we evaluated the effect of chitosan nanoparticles on the acid tolerance response (ATR) of adhered Streptococcus mutans. An ATR was induced by exposing S. mutans to pH 5.5 for 2 h and confirmed by exposing the acid-adapted cells to pH 3.5 for 30 min, with the majority of cells appearing viable according to the LIVE/DEAD® technique. However, when chitosan nanoparticles were present during the exposure to pH 5.5, no ATR occurred as most cells appeared dead after the pH 3.5 shock. We conclude that the chitosan nanoparticles tested had the ability to hinder ATR induction in adhered S. mutans.

journal_name

Caries Res

journal_title

Caries research

authors

Neilands J,Sutherland D,Resin A,Wejse PL,Chávez de Paz LE

doi

10.1159/000331206

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

501-5

issue

6

eissn

0008-6568

issn

1421-976X

pii

000331206

journal_volume

45

pub_type

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