Abstract:
:Since the late 1970s, 8.4 million people worldwide, including 1.7 million children, have died of AIDS, and an estimated 22 million people are infected with human immunodeficiency virus (HIV)(1). During 1995 and 1996, major clinical and laboratory discoveries regarding HIV pathogenesis provided new hope for the prevention and treatment of HIV infection. One major discovery was that members of the chemokine receptor family serve as cofactors for HIV entry into cells. We describe the role of allelic polymorphism in the gene coding for the CCR5 chemokine receptor with regard to susceptibility to and disease course of HIV infection. We also examine the effect of this discovery on medical and public health practices.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
McNicholl JM,Smith DK,Qari SH,Hodge Tdoi
10.3201/eid0303.970302subject
Has Abstractpub_date
1997-07-01 00:00:00pages
261-71issue
3eissn
1080-6040issn
1080-6059journal_volume
3pub_type
杂志文章,评审abstract::Brucellosis causes appreciable economic losses in livestock. Examination of milk and tissues from animals in Egypt for Brucella spp. showed increased prevalence rates of serologically reactive animals. All isolates were B. melitensis biovar 3. One Brucella sp. was isolated from milk of serologically nonreactive buffal...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.3201/eid1412.071452
更新日期:2008-12-01 00:00:00
abstract::A 56-year-old man receiving rituximab who had months of neurologic symptoms was found to have Jamestown Canyon virus in cerebrospinal fluid by clinical metagenomic sequencing. The patient died, and postmortem examination revealed extensive neuropathologic abnormalities. Deep sequencing enabled detailed characterizatio...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2701.203448
更新日期:2021-01-01 00:00:00
abstract::The severe epidemic of Ebola virus disease in Liberia started in March 2014. On May 9, 2015, the World Health Organization declared Liberia free of Ebola, 42 days after safe burial of the last known case-patient. However, another 6 cases occurred during June-July; on September 3, 2015, the country was again declared f...
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pub_type: 历史文章,杂志文章
doi:10.3201/eid2202.151456
更新日期:2016-02-01 00:00:00
abstract::We studied the role of European rabbits (Oryctolagus cuniculus) as a reservoir for Coxiella burnetii in the Iberian region. High individual and population seroprevalences observed in wild and farmed rabbits, evidence of systemic infections, and vaginal shedding support the reservoir role of the European rabbit for C. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2106.141537
更新日期:2015-06-01 00:00:00
abstract::Human penicilliosis marneffei is an emerging infectious disease caused by the fungus Penicillium marneffei. High prevalence of infection among bamboo rats of the genera Rhizomys and Cannomys suggest that these rodents are a key facet of the P. marneffei life cycle. We trapped bamboo rats during June 2004-July 2005 acr...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1702.100718
更新日期:2011-02-01 00:00:00
abstract::Host association of Campylobacter jejuni was analyzed by using multilocus sequence typing data for 713 isolates from chickens and bovids (cattle and sheep). Commonly used summary measures of genotypes (sequence type and clonal complex) showed poor accuracy, but a method using the full allelic profile showed 80% accura...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1302.060620
更新日期:2007-02-01 00:00:00
abstract::During an investigation conducted December 17-20, 2001, we collected environmental samples from a U.S. postal facility in Washington, D.C., known to be extensively contaminated with Bacillus anthracis spores. Because methods for collecting and analyzing B. anthracis spores have not yet been validated, our objective wa...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0810.020382
更新日期:2002-10-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid0302.970202
更新日期:1997-04-01 00:00:00
abstract::We describe a patient in Wuhan, China, with severe acute respiratory syndrome coronavirus 2 infection who had progressive pulmonary lesions and rhabdomyolysis with manifestations of lower limb pain and fatigue. Rapid clinical recognition of rhabdomyolysis symptoms in patients with severe acute respiratory syndrome cor...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2607.200445
更新日期:2020-07-01 00:00:00
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journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1205.050560
更新日期:2006-03-01 00:00:00
abstract::Highland areas where malaria transmission is unstable are targets for malaria elimination because transmission decreases to low levels during the dry season. In highland areas of Kipsamoite and Kapsisiywa, Kenya (population approximately 7,400 persons), annual household indoor residual spraying with a synthetic pyreth...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1512.090627
更新日期:2009-12-01 00:00:00
abstract::Prior immunization of hamsters with three heterologous flaviviruses (Japanese encephalitis virus [JEV] SA14-2-8 vaccine, wild-type St. Louis encephalitis virus [SLEV], and Yellow fever virus [YFV] 17D vaccine) reduces the severity of subsequent West Nile virus (WNV) infection. Groups of adult hamsters were immunized w...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0803.010238
更新日期:2002-03-01 00:00:00
abstract::This issue of Emerging Infectious Diseases contains 2 articles that report increases in England in the incidence of hospitalizations for specific diseases, one on pneumonias and the other on community-acquired staphylococcal diseases. Both articles report increases in disease among those >65 years of age. ...
journal_title:Emerging infectious diseases
pub_type: 评论,杂志文章
doi:10.3201/eid1405.080218
更新日期:2008-05-01 00:00:00
abstract::To study a 2001 dengue fever outbreak in Iracoubo, French Guiana, we recorded the location of all patients' homes and the date when symptoms were first observed. A geographic information system (GIS) was used to integrate the patient-related information. The Knox test, a classic space-time analysis technique, was used...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1004.030186
更新日期:2004-04-01 00:00:00
abstract::A previously healthy man from eastern Kansas, USA, sought medical care in late spring because of a history of tick bite, fever, and fatigue. The patient had thrombocytopenia and leukopenia and was given doxycycline for a presumed tickborne illness. His condition did not improve. Multiorgan failure developed, and he di...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2105.150150
更新日期:2015-05-01 00:00:00
abstract::Fourteen influenza A(H7N9) viruses were isolated from poultry or the environment in live poultry markets in Guangdong Province, China during 2014-2015. Phylogenetic analysis showed that all viruses were descended from viruses of the second wave of influenza A(H7N9) virus infections during 2013. These viruses can be di...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2109.150635
更新日期:2015-09-01 00:00:00
abstract::Conjugate vaccines have reduced the incidence of invasive disease caused by Haemophilus influenzae, type b (Hib), in industrialized countries and may be highly effective against Streptococcus pneumoniae. However, the serotype specificity of these vaccines has led to concern that their use may increase carriage of and ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0503.990304
更新日期:1999-05-01 00:00:00
abstract::This study is the first confirmation of Rickettsia felis in Australia. The organism was identified from 4 species of fleas obtained from dogs and cats in Western Australia, by using polymerase chain reaction amplification and DNA sequencing of the citrate synthase and outer membrane protein A genes. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1205.051458
更新日期:2006-05-01 00:00:00
abstract::Primary bloodstream infection (BSI) is a leading, preventable infectious complication in critically ill patients and has a negative impact on patients' outcome. Surveillance definitions for primary BSI distinguish those that are microbiologically documented from those that are not. The latter is known as clinical seps...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1001.030407
更新日期:2004-01-01 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) continues to be a notable cause of hospital-acquired infections. A statewide screening and control policy was implemented in Western Australia (WA) after an outbreak of epidemic MRSA in a Perth hospital in 1982. We report on statutory notifications from 1998 to 2002 a...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1110.050125
更新日期:2005-10-01 00:00:00
abstract::A decision analytical model was developed to investigate the cost-effectiveness of stockpiling antiviral (AV) drugs for a potential influenza pandemic in the United Kingdom and the possible role of near-patient testing in conserving AV drug stocks. Under base-case assumptions (including a fixed stockpile that was smal...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1402.070478
更新日期:2008-02-01 00:00:00
abstract::We evaluated West Nile (WN) virus seroprevalence in healthy horses, dogs, and cats in New York City after an outbreak of human WN virus encephalitis in 1999. Two (3%) of 73 horses, 10 (5%) of 189 dogs, and none of 12 cats tested positive for WN virus-neutralizing antibodies. Domestic mammals should be evaluated as sen...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0704.010424
更新日期:2001-07-01 00:00:00
abstract::In 2008, acute hepatitis E infection was confirmed in 4 passengers returning to the United Kingdom after a world cruise. Epidemiologic investigation showed that of 789 persons who provided blood samples, 195 (25%) were seropositive, 33 (4%) had immunoglobulin [Ig] M levels consistent with recent acute infection (11 of...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1511.091094
更新日期:2009-11-01 00:00:00
abstract::Extended-spectrum β-lactamase (ESBL)- and plasmid-encoded ampC (pAmpC)-producing Enterobacteriaceae might spread from farm animals to humans through food. However, most studies have been limited in number of isolates tested and areas studied. We examined genetic relatedness of 716 isolates from 4,854 samples collected...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2204.151142
更新日期:2016-04-01 00:00:00
abstract::Human papillomavirus (HPV) has been implicated as the primary etiologic agent of cervical cancer. Potential vaccines against high-risk HPV types are in clinical trials. We evaluated vaccination programs with a vaccine against HPV-16 and HPV-18. We developed disease transmission models that estimated HPV prevalence and...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1011.040222
更新日期:2004-11-01 00:00:00
abstract::We describe a case of treatment failure caused by a strain of USA300 community-associated methicillin-resistant Staphylococcus aureus (MRSA) with intermediate susceptibility to vancomycin and reduced susceptibility to daptomycin. The strain was isolated from the bone of a 56-year-old man with lumbar osteomyelitis afte...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1303.060960
更新日期:2007-03-01 00:00:00
abstract::We conducted a program of population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2452 isolates, 1013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of rel...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0811.020292
更新日期:2002-11-01 00:00:00
abstract::Subclinical infection of vaccinated chickens with a highly pathogenic avian influenza A(H5N2) virus was identified through routine surveillance in China. Investigation suggested that the virus has evolved into multiple genotypes. To better control transmission of the virus, we recommend a strengthened program of educa...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2012.140733
更新日期:2014-12-01 00:00:00
abstract::A task force of experts on influenza, public health, and animal health met at the conference One Health Approach to Influenza: Assessment of Critical Issues and Options in Washington, DC, on December 1-2, 2009. These experts discussed the role of the One Health approach in preparing for and responding to an influenza ...
journal_title:Emerging infectious diseases
pub_type: 共识发展会议,杂志文章
doi:10.3201/eid1608.100673
更新日期:2010-08-01 00:00:00
abstract::Using reported case data from ArboNET and previous seroprevalence data stratified by age and sex, we conservatively estimate that ≈7 million persons in the United States have been infected with West Nile virus since its introduction in 1999. Our data support the need for public health interventions and improved survei...
journal_title:Emerging infectious diseases
pub_type: 历史文章,杂志文章
doi:10.3201/eid2502.180765
更新日期:2019-02-01 00:00:00