Abstract:
:A previously healthy man from eastern Kansas, USA, sought medical care in late spring because of a history of tick bite, fever, and fatigue. The patient had thrombocytopenia and leukopenia and was given doxycycline for a presumed tickborne illness. His condition did not improve. Multiorgan failure developed, and he died 11 days after illness onset from cardiopulmonary arrest. Molecular and serologic testing results for known tickborne pathogens were negative. However, testing of a specimen for antibodies against Heartland virus by using plaque reduction neutralization indicated the presence of another virus. Next-generation sequencing and phylogenetic analysis identified the virus as a novel member of the genus Thogotovirus.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Kosoy OI,Lambert AJ,Hawkinson DJ,Pastula DM,Goldsmith CS,Hunt DC,Staples JEdoi
10.3201/eid2105.150150subject
Has Abstractpub_date
2015-05-01 00:00:00pages
760-4issue
5eissn
1080-6040issn
1080-6059journal_volume
21pub_type
杂志文章abstract::Severe acute respiratory syndrome coronavirus 2 readily transmits between domestic cats. We found that domestic cats that recover from an initial infection might be protected from reinfection. However, we found long-term persistence of inflammation and other lung lesions after infection, despite a lack of clinical sym...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2702.203884
更新日期:2021-02-01 00:00:00
abstract::We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in RNA polymerase and S133A in hemagglutinin) were detected in virus isolates from 2 siblings who died. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1403.061237
更新日期:2008-03-01 00:00:00
abstract::To determine the usefulness of noninvasive cutaneous swab specimens for detecting rickettsiae, we tested skin eschars from 6 guinea pigs and from 9 humans. Specimens from eschars in guinea pigs were positive for rickettsiae as long as lesions were present. Optimal storage temperature for specimens was 4 degrees C for ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1701.100854
更新日期:2011-01-01 00:00:00
abstract::We detected Marburg virus genome in Egyptian fruit bats (Rousettus aegyptiacus) captured in Zambia in September 2018. The virus was closely related phylogenetically to the viruses that previously caused Marburg outbreaks in the Democratic Republic of the Congo. This finding demonstrates that Zambia is at risk for Marb...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2508.190268
更新日期:2019-08-01 00:00:00
abstract::To further assess the geographic occurrence, possible vectors, and prevalence of Candidatus Neoehrlichia mikurensis, we analyzed spleen tissues from 276 voles trapped close to human settlements in France; 5 were infected with the organism. Sequencing showed the isolates carried the same genotype as the bacteria that c...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1812.120846
更新日期:2012-12-01 00:00:00
abstract::Worldwide, West Nile virus (WNV) causes encephalitis in humans, horses, and birds. The Kunjin strain of WNV (WNVKUN) is endemic to northern Australia, but infections are usually asymptomatic. In 2011, an unprecedented outbreak of equine encephalitis occurred in southeastern Australia; most of the ≈900 reported cases w...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2208.151719
更新日期:2016-08-01 00:00:00
abstract::Neisseria meningitidis sequence type 11 is an emerging cause of urethritis. We demonstrate by using whole-genome sequencing orogenital transmission of a N. meningitidis sequence type 11 isolate causing urethritis in a monogamous couple of men who have sex with men. These results suggest dissemination of this clonal co...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2501.171102
更新日期:2019-01-01 00:00:00
abstract::Saudi Arabia has reported >80% of the Middle East respiratory syndrome coronavirus (MERS-CoV) cases worldwide. During April 2015-February 2016, Saudi Arabia identified and tested 57,363 persons (18.4/10,000 residents) with suspected MERS-CoV infection; 384 (0.7%) tested positive. Robust, extensive, and timely surveill...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2304.161793
更新日期:2017-04-01 00:00:00
abstract::Leptospirosis is a neglected zoonotic disease. In 2015, leptospirosis was diagnosed in 2 prison inmates in South Africa. Using real-time PCR and DNA sequencing, we identified Leptospira interrogans serogroup Icterohaemorrhagiae in rodents and water samples within the prison. Leptospirosis might be frequently underdiag...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2605.191132
更新日期:2020-05-01 00:00:00
abstract::During a 2014 outbreak, 450 patients with confirmed chikungunya virus infection were admitted to the University Hospital of Pointe-à-Pitre, Guadeloupe. Of these, 110 were nonpregnant adults; 42 had severe disease, and of those, 25 had severe sepsis or septic shock and 12 died. Severe sepsis may be a rare complication ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2205.151449
更新日期:2016-05-01 00:00:00
abstract::WU polyomavirus (WUPyV) and KI polyomavirus (KIPyV) are novel human polyomaviruses. They were originally identified in human respiratory secretions, but the extent of human infection caused by these viruses has not been described to date. To determine the seroepidemiology of WUPyV and KIpyIV, we used an ELISA to scree...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1508.090270
更新日期:2009-08-01 00:00:00
abstract::We analyzed 43 CTX-M-15-producing Escherichia coli isolates and 6 plasmids encoding the blaCTX-M-15 gene from Canada, India, Kuwait, France, Switzerland, Portugal, and Spain. Most isolates belonged to phylogroups B2 (50%) and D (25%). An EC-B2 strain of clonal complex sequence type (ST) 131 was detected in all countri...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1402.070350
更新日期:2008-02-01 00:00:00
abstract::West Nile virus (WNV) lineage 2 is associated with neurologic disease in horses and humans in South Africa. Surveillance in wildlife and nonequine domestic species during 2010-2018 identified WNV in 11 (1.8%) of 608 animals with severe neurologic and fatal infections, highlighting susceptible hosts and risk for WNV ep...
journal_title:Emerging infectious diseases
pub_type: 历史文章,杂志文章
doi:10.3201/eid2512.190572
更新日期:2019-12-01 00:00:00
abstract::During a surveillance study of patients in a long-term care facility and the affiliated acute care hospital in the United States, we identified a Clostridioides difficile strain related to the epidemic PCR ribotype (RT) 027 strain associated with hospital outbreaks of severe disease. Fifteen patients were infected wit...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.3201/eid2602.181965
更新日期:2020-02-01 00:00:00
abstract::Zoonoses with a wildlife reservoir represent a major public health problem, affecting all continents. Hundreds of pathogens and many different transmission modes are involved, and many factors influence the epidemiology of the various zoonoses. The importance and recognition of wildlife as a reservoir of zoonoses are ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid1012.040707
更新日期:2004-12-01 00:00:00
abstract::We report the first genetic characterization of wildtype measles viruses from Uganda. Thirty-six virus isolates from outbreaks in 6 districts were analyzed from 2000 to 2002. Analyses of sequences of the nucleoprotein (N) and hemagglutinin (H) genes showed that the Ugandan isolates were all closely related, and phylog...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1110.050431
更新日期:2005-10-01 00:00:00
abstract::Arboviruses have evolved a number of strategies to survive environmental challenges. This review examines the factors that may determine arbovirus emergence, provides examples of arboviruses that have emerged into new habitats, reviews the arbovirus situation in western Europe in detail, discusses potential arthropod ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid1204.051010
更新日期:2006-04-01 00:00:00
abstract::Adjustable rate mortgages and the downturn in the California housing market caused a 300% increase in notices of delinquency in Bakersfield, Kern County. This led to large numbers of neglected swimming pools, which were associated with a 276% increase in the number of human West Nile virus cases during the summer of 2...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1411.080719
更新日期:2008-11-01 00:00:00
abstract::Several unique features characterize infectious disease epidemiology in New Zealand. Historically, well-organized, government-run control programs have eliminated several zoonoses. More recently, however, communicable disease control has been mixed. Rates of rheumatic fever, tuberculosis, and enteric infectious are hi...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid0705.017501
更新日期:2001-09-01 00:00:00
abstract::Although surgical site infections (SSIs) are known to cause substantial illness and costs during the index hospitalization, little information exists about the impact of infections diagnosed after discharge, which constitute the majority of SSIs. In this study, using patient questionnaire and administrative databases,...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0902.020232
更新日期:2003-02-01 00:00:00
abstract::From January 1995 through July 1998, we investigated the occurrence of Cyclospora cayetanensis infection associated with gastrointestinal illness or diarrhea in foreign residents and natives of West Java, Indonesia. We found that C. cayetanensis was the main protozoal cause of gastrointestinal illness and diarrhea in ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0504.990426
更新日期:1999-07-01 00:00:00
abstract::In the context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly promoted, but concerns about the risk for development of isoniazid-resistant tuberculosis may hinder its widespread implementation. We conducted a systematic review of data published since 1951 to assess the effect of pr...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,meta分析,评审
doi:10.3201/eid1205.050681
更新日期:2006-05-01 00:00:00
abstract::To determine whether guinea pigs are infected with influenza virus in nature, we conducted a serologic study in domestic guinea pigs in Ecuador. Detection of antibodies against influenza A and B raises the question about the role of guinea pigs in the ecology and epidemiology of influenza virus in the region. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1807.111930
更新日期:2012-07-01 00:00:00
abstract::Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2510.190607
更新日期:2019-10-01 00:00:00
abstract::We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion intervals with previous and subsequent intervals, we found that ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2004.131015
更新日期:2014-04-01 00:00:00
abstract::[This corrects the article on p. 1690 in vol. 23, PMID: 28930024.]. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,已发布勘误
doi:10.3201/eid2402.C12402
更新日期:2018-02-01 00:00:00
abstract::During an 8-year study period, Arcobacter butzleri was the fourth most common Campylobacter-like organism isolated from 67,599 stool specimens. Our observations suggest that A. butzleri displays microbiologic and clinical features similar to those of Campylobacter jejuni; however, A. butzleri is more frequently associ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1010.040241
更新日期:2004-10-01 00:00:00
abstract::We used whole-genome sequence typing (WGST) to investigate an outbreak of Sarocladium kiliense bloodstream infections (BSI) associated with receipt of contaminated antinausea medication among oncology patients in Colombia and Chile during 2013-2014. Twenty-five outbreak isolates (18 from patients and 7 from medication...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2203.151193
更新日期:2016-03-01 00:00:00
abstract::To understand the clinical and epidemiologic characteristics of pandemic (H1N1) 2009 virus infection, we retrospectively reviewed medical records of 237 patients with laboratory-confirmed cases reported in Shanghai, China, during May-July 2009. Surveillance activities effectively contained the outbreak and provided us...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1606.090991
更新日期:2010-06-01 00:00:00
abstract::We conducted a program of population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2452 isolates, 1013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of rel...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0811.020292
更新日期:2002-11-01 00:00:00