Abstract:
:Cell kinetic information is an important adjuvant to histological typing and grading of human brain tumours. In the current study detection of the proliferating potential of adenomas was attempted using silver colloid technique for argyrophilic protein associated with nucleolar organizer regions (AgNORs). The expression of nucleolar organizer regions was assessed on paraffin sections in 28 pituitary macroadenomas which included all the main types. Nucleolar organiser regions have been quantified with computer-aided image analysis system in order to evaluate the mean area of AgNORs and their number relative to an internal reference, the number and areas of clusters of AgNORs and the area of the nucleus. In the pituitary macroadenomas there were 1.48 +/- 0.30 (mean +/- SEM) AgNORs per cell nucleus and corrected values were 1.66 +/- 0.27 (mean +/- SEM) AgNORs. The mean nucleus area was 867.18 +/- 203.91 pixels. The mean AgNORs size was 54.50 +/- 34.80 pixels. Correlation of nucleus area/AgNORs area was: r = 0.7085. On the number of the AgNORs it was possible to distinguish 3 subgroups of macroadenoma with different proliferative potential: low < = 1.367 (1.479); medium 1.367-1.733 (1.479-1.864) and high > 1.733 (1.864) AgNORs per cell nucleus and corrected number of AgNORs per cell nucleus respectively. Thus, this method provides useful information about the proliferative potential of human pituitary adenoma.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Szymaś J,Liebert W,Beil Msubject
Has Abstractpub_date
1999-09-01 00:00:00pages
1089-97issue
5eissn
0028-3843issn
1897-4260journal_volume
33pub_type
杂志文章abstract::Using the method of Park et al. the author studied spontaneous and stimulated NBT reduction by neutrophil granulocytes in the cerebrospinal fluid and blood, and by monocytic-reticular cells in the cerebrospinal fluid of the patients with bacterial and viral meningitis and meningismus. The author performed 333 investig...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1980-07-01 00:00:00
abstract:INTRODUCTION:Tremor is the most prevalent movement disorder, defined as rhythmic oscillations of a body part, caused by alternating or synchronic contractions of agonistic or antagonistic muscles. The aim of the study was to assess prevalence and to characterize parameters of tremor accompanying de-generative ataxias, ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.5114/ninp.2013.35585
更新日期:2013-05-01 00:00:00
abstract::The authors report the results of EEG monitoring lasting many hours with cassette recording and with interpretation after reproduction on monitor screen. The Medilog 9000 System Oxford was used for that purpose. The group comprised 32 verified cases of epilepsy and 19 cases of seizures with unestablished aetiology. In...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Tiagabine (TGB) is a novel anti-epileptic drug providing new therapeutic possibilities to patients with focal seizures resistant to treatment. Since there is no clear algorithm for the best add-on therapy, the aim of our work was to establish factors that statistically significantly affect tiagabine efficacy and toxic...
journal_title:Neurologia i neurochirurgia polska
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2003-05-01 00:00:00
abstract::Authors evaluated the activity of c-AMP in the CSF as the biochemical marker for evaluation of epileptic seizure activity in patients with epilepsy. The impact of monitored phenytoin treatment on c-AMP activity in CSF was investigated. It was shown that the general tonic-clonic seizures cause a significant concentrati...
journal_title:Neurologia i neurochirurgia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::The group of 20 patients with the preliminary diagnosis of occlusive hydrocephalus were treated by neuroendoscopic technique. Ten ventriculocystocisternostomies in cases with third ventricle arachnoid cysts accompanied by hydrocephalus, 9 ventriculostomies, and 1 ventriculostomy with fenestration of posterior fossa cy...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The aim of the study was to evaluate effects of cranio-cerebral trauma on gastric myoelectric activity. Twenty four patients hospitalized in the Department of Neurotraumatology, Collegium Medicum of the Jagiellonian University were compared with a control group of 16 healthy volunteers matched for gender and age. Thei...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract::Clinical course of disease and results of EEG examinations of 6 patients with severe brain disturbances of various aetiology provided grounds for discussion on the phenomenon of periodic stereotyped EEG discharges (PSD) which is of considerable diagnostic value in some cases. The variability in appearance of these dis...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1977-03-01 00:00:00
abstract::A case of conus medullaris tumour (ependymoma) is reported in which the presenting symptom was subarachnoid haemorrhage, which has left bladder dysfunction. 70-year-old patient was admitted to the Department of Neurology due to symptoms of conus medullaris lesion with retention of urine and diminished pain sensitivity...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::The authors studied 14 patients with epileptic seizures occurring from one to about 20 daily despite monitored pharmacological treatment. Two pairs of silver, properly insulated electrodes were applied to the subtentorial surface of both cerebellar hemispheres through burr-holes. The cerebellar surface was stimulated ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1981-09-01 00:00:00
abstract:AIM OF THE STUDY:The goal of the present study was to analyse the exclusive use of absorbable suture material (Vicryl) in the fixation of transposed bone segments in cranial vault reshaping without modification of the osteotomy design. CLINICAL RATIONALE FOR THE STUDY:In the surgical correction of craniosynostosis, bo...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.5603/PJNNS.a2019.0014
更新日期:2019-01-01 00:00:00
abstract::The authors present the results of own investigations on the occurrence of side effects following myelography with the contrast medium Amipaque administered usually by the lumbar route. Sixty patients aged 21-65 years with various diseases of the spinal cord and cauda equina were studied. Clinical and myelographic inv...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1985-05-01 00:00:00
abstract::In 24 patients with diagnostically not clear, short, recurrent episodes of consciousness disturbances and heart diseases and/or a history of arrhythmia simultaneous 24-hour recording was done of eeg and ecg. In the differential diagnosis epilepsy was considered, especially since in most cases routine eeg records demon...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::Matrix metalloproteinase-9 (MMP-9) is a member of the family of zinc-dependent endopeptidases that degrade extracellular matrix proteins. It can be activated by serine proteinases or by superoxide radicals. The motor neurons in amyotrophic lateral sclerosis patients express significantly higher levels of MMP-9, sugges...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::Most recent studies on transcranial Doppler (TCD) in the acute phase of ischemic stroke are reviewed in this paper. TCD is a highly sensitive and specific method of quick, bedside assessment of cerebrovascular circulation hemodynamics in the acute phase of ischemic stroke. The following issues are discussed in the pap...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:Patients with obstructive sleep apnoea syndrome (OSAS) can be more prone to accidents due to excessive daytime sleepiness which can lead to attention deficits and thereby cause balance problems. One of the tests evaluating postural balance is static posturography (SPG). In this study, we aimed to evaluate ...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.5603/PJNNS.a2019.0059
更新日期:2020-01-01 00:00:00
abstract:AIM:Sialorrhea is one of the main problems of patients with Parkinson's disease (PD). Most of the medications used for the treatment of it are ineffective. We decided to try in such patients local injections of botulinum toxin, type A, into both parotid glands. MATERIAL:11 patients with clinical diagnosis of idiopathi...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Determinations of AMP-aminohydrolase activity were done in muscles in 34 cases of different neuromuscular diseases, and 30 subjects without skeletal muscle changes. In the group of patients Duchenne's progressive dystrophy accounted for 10 cases, the remaining patients had limb-girdle dystrophy, polymyositis, myotonia...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract::The aim of the study was to establish the prognostic value of early CT findings in predicting the 30-day mortality after stroke, to assess the prevalence of these findings in acute stroke patients, and to examine the correlation between these findings and the clinical status. 134 patients (mean age 67.5 +/- 12.1) with...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract::Mössbauer spectroscopy was used to study iron content, its redox state and binding sites in substantia nigra from parkinsonian and control brains. Measurements performed on fresh frozen samples demonstrated the presence of ferric iron only, both in disease and control. We found no difference in the total amount of iro...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The authors report the results of investigations of 33 healthy subjects and 33 patients with manifestations of intracranial circulatory disturbances in the vascularization area of the vertebrobasilar system. Type II rheography was used. All curves from the vertebral, vertebromastoid and frontomastoid leads were averag...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1982-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Feasibility study and evaluation of complications of two different C1-C2 motion-sparing surgical methods for hangman's fracture of C2. MATERIAL AND METHODS:From 2001 till 2005, seventeen patients were operated on because of unstable type II (according to Effendi) hangman's fractures. The patient...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The outcome in acute stroke strongly depends on patient-related issues, as well as on the availability of human and diagnostic resources. Our aim was to evaluate safety and effectiveness of intravenous alteplase for stroke according to the time of admission to the hospital. MATERIALS AND METHODS...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.1016/j.pjnns.2013.12.003
更新日期:2014-01-01 00:00:00
abstract::A statistical analysis of CSF lactate concentration and CSF pH and PCO2 was performed. The values were obtained from 211 samples taken from 76 neurosurgical patients. The values of pH and pCO2 were classified in three groups corresponding to the following three ranges of lactate concentration: below 15 mg%, 15-30 mg%,...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::Apart from intention tremor essential tremor (ET) patients may display other cerebellar signs, like dysmetria or tandem gait disturbances as well as parkinsonian signs like resting tremor, cogwheel sign, subtle bradykinesia. Previous reports claimed the occurrence of the eye movement abnormalities characteristic for d...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:10.1016/j.pjnns.2017.05.001
更新日期:2017-01-01 00:00:00
abstract::Deep brain stimulation (DBS) is an established and accepted treatment modality of generalized dystonia. The stereotactic target to be approached with DBS leads is the internal segment of the globus pallidus (GPi). Bilateral GPi stimulation in patients suffering from primary generalized dystonia reduced dystonic moveme...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:10.1016/s0028-3843(14)60127-4
更新日期:2011-11-01 00:00:00
abstract::The superficial siderosis (SS) of the central nervous system (CNS) is a rare condition characterized by a wide range of neurological manifestations directly linked to an acquired iron-mediated neurodegeneration. First described more than 100 years ago, only recently SS has been divided into two distinct entities, acco...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章,评审
doi:10.1016/j.pjnns.2017.10.006
更新日期:2018-01-01 00:00:00
abstract::The aim of this study is to present a clinical role for 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in the differential diagnosis in patients with parkinsonian syndromes. We present a 51-year-old woman with parkinsonian syndrome and syncope occurrence. She reproduced spontaneous syncope in the tilt tes...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of our study was to evaluate brain perfusion in patients with vertigo using the SPECT technique. METHODS:The study involved a group of 32 patients and was performed in the Neurological Department of the Medical University in Bialystok. Patients with vertigo of peripheral origin like midd...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract::In 18 men with Horton's headaches the levels of the following hormones were determined in the serum: TSH, T3 and T4. The determinations were performed during disease relapse and before starting treatment. The control group included 18 blood donors. In the control group the mean TSH level was 3.97 +/- 0.88 microunits/m...
journal_title:Neurologia i neurochirurgia polska
pub_type: 杂志文章
doi:
更新日期:1981-09-01 00:00:00