Abstract:
OBJECTIVE:To demonstrate that after spinal cord injury (SCI) suppression of the parathyroid-vitamin D axis is associated with the degree of neurologic impairment and not the level of injury. DESIGN:A retrospective analysis of clinical and biochemical data obtained from hospital records of patients with SCI compared to a control group of patients with traumatic brain injury (TBI). SETTING:The inpatient rehabilitation unit of a tertiary care hospital. SUBJECTS:The medical records of 82 consecutive admissions to the rehabilitation unit with a diagnosis of SCI or TBI were reviewed. Patients with SCI were classified by the American Spinal Injury Association (ASIA) impairment scale and then grouped based on the completeness and level of injury. MAIN OUTCOME MEASURE:Comparisons of serum parathyroid hormone (PTH), 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D (1,25-D) were planned. Multiple comparisons were performed for total and ionized serum calcium levels, serum phosphorus levels, and 24-hour urinary calcium excretion rates to reflect changes in mineral homeostasis. Multiple comparisons were also performed for serum albumin, prolactin, thyroid function tests, and AM cortisol levels, as well as 24-hour urinary urea nitrogen and cortisol excretion rates to reflect metabolic responses to stress. RESULTS:Patients with SCI had significant suppression in PTH (p < .000009) and 1,25-D (p < .02) levels with elevated phosphorus (p < 0.03) and prolactin (p < .03) levels compared to patients with TBI. Also, more patients with SCI were hypoalbuminemic (p < .003) than patients with TBI. Patients with complete SCI (ASIA A) had more suppressed PTH (p < .03) and higher urinary urea nitrogen (p < .05) levels than SCI patients with incomplete injuries (ASIA B-D). Patients with complete, but not incomplete, SCI had lower albumin levels than patients with TBI (p < .05). These differences were not found between patients with tetraplegic and paraplegic SCI. ASIA motor scores did not correlate with any of the measured parameters but when used as a covariate did abolish differences in PTH and 1,25-D among the study groups by ANOVA. CONCLUSION:In patients with SCI, the degree of neurologic impairment, and not the level of injury, is associated with PTH suppression and markers of metabolic stress.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Mechanick JI,Pomerantz F,Flanagan S,Stein A,Gordon WA,Ragnarsson KTdoi
10.1016/s0003-9993(97)90075-7subject
Has Abstractpub_date
1997-07-01 00:00:00pages
692-6issue
7eissn
0003-9993issn
1532-821Xpii
S0003-9993(97)90075-7journal_volume
78pub_type
杂志文章abstract::Safe assessment of standing balance and gait is often jeopardized by the potential for falls, which may have major physical and legal consequences. This article describes the design and use of a system that enhances the safety of the patient and clinician during balance and gait assessment and training. The system con...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVES:To determine the relative and absolute reliability of the assessment of ambulatory walking activity during 2 consecutive weeks in patients with hematologic malignancies recovering at home from their medical treatment and to compare the physical activity level of hematologic cancer patients after high-dose ch...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2008.06.020
更新日期:2009-01-01 00:00:00
abstract::Atrial fibrillation is an arrhythmia characterized by disorganized atrial depolarizations and an irregular ventricular response. Most patients with atrial fibrillation have underlying cardiac pathology. This paper presents the cases of three patients with high-level spinal cord injury and symptoms of autonomic dysrefl...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVES:To examine the safety, feasibility, and balance performance effects of a 4-week home-based balance therapy program using a commercially available videogame system. DESIGN:A pilot study involving a preintervention and postintervention design was conducted with measurements taken at baseline, immediately post...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2011.08.031
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of 2 rehabilitative approaches for improving paretic limb reaching by chronic stroke subjects. DESIGN:Pre- and posttest reaching to targets ipsilateral, midline, and contralateral to the impaired side. SETTING:Training in subjects' homes; testing in a laboratory setting. PARTI...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.apmr.2004.01.028
更新日期:2004-10-01 00:00:00
abstract::The pneumatic orthosis is potentially a substitute or replacement for conventional long-ler and under outer clothing. Pneumatic tubes are incorporated into the orthosis and may be inflated at will by the patient. In a preliminary test it was found to be lighter, more comfortable and cosmetically more acceptable than...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:To examine the system of connections among traumatic brain injury (TBI) patient social functioning, family functioning, and caregiver depression and burden in Mexico. DESIGN:Cross-sectional survey. SETTING:A public medical facility. PARTICIPANTS:Mexican TBI patient-caregiver dyads (N=84) participated in th...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2012.08.210
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To assess perceptual performances of patients with intracerebral hemorrhage (ICH) compared with those of ischemic patients early after stroke and to analyze the psychometric properties of three perceptual tests used in the study. DESIGN:Cross-sectional study. SETTING:A rehabilitation unit at a teaching hosp...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(00)90097-2
更新日期:2000-06-01 00:00:00
abstract::Postdischarge progress in 11 types of patients was analyzed with regard to eating, dressing, transfers, bladder management, ambulation, cognition, language comprehension and speech, placement (living arrangement), and mortality rates. Of 273 patients admitted, 263 were available for foillow-up, which disclosed that pa...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1980-08-01 00:00:00
abstract:OBJECTIVE:To compare 3-dimensional (3D) shoulder joint reaction forces and stride characteristics during bilateral forearm crutches and front-wheeled walker ambulation in persons with incomplete spinal cord injury (SCI). DESIGN:Cross-sectional cohort study. SETTING:Biomechanics laboratory. PARTICIPANTS:Fourteen adul...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2005.07.311
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The primary aim of this study was to assess the intrarater reliability of ultrasonographic measurements of acromion-greater tuberosity (AGT) distance in patients with stroke using portable ultrasound. A secondary aim was to determine the discriminant validity of the ultrasonographic technique by comparison o...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2010.10.018
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To investigate the characteristics of rehabilitation hospitals and units correlated with gains in motor and cognitive function, after adjusting for case severity of the patients admitted and for length of stay (LOS). DESIGN:The Uniform Data System for Medical Rehabilitation (UDSMR) database was first analyze...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1053/apmr.2003.50009
更新日期:2003-03-01 00:00:00
abstract::This article introduces the Archives supplement presenting a conceptual framework for the creation of a rehabilitation treatment taxonomy (RTT). It describes the key theoretical and empirical articles and their role, and the commentaries that were solicited. More importantly, based on feedback received to date, it ske...
journal_title:Archives of physical medicine and rehabilitation
pub_type:
doi:10.1016/j.apmr.2013.09.023
更新日期:2014-01-01 00:00:00
abstract::This double-blind cross-over study of 14 severely spastic inpatients with chronic multiple sclerosis reveals that once-daily doses of ketazolam, a new drug, are effective in reducing spasticity in a significant proportion of patients without significant side-effects. Added to the similar findings of an earlier double-...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract:OBJECTIVE:To determine the impact of long-term, body weight-supported locomotor training after chronic, incomplete spinal cord injury (SCI), and to estimate the health care costs related to lost recovery potential and preventable secondary complications that may have occurred because of visit limits imposed by insurers...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2017.10.003
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To investigate the physiologic differences during multispeed treadmill walking and physical activity profiles for the Otto Bock C-Walk foot (C-Walk), Flex-Foot, and solid ankle cushion heel (SACH) foot in people with transtibial amputation. DESIGN:A repeated-measures design with 3 prostheses. SETTING:Resear...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2005.07.310
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To determine whether the preferred pattern of arm use after unilateral hemispheric damage was associated with better everyday functioning. Our previous work showed that right-handed stroke patients with right hemisphere damage (RHD) used their right, ipsilesional arm most frequently, while those with left hem...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2012.05.011
更新日期:2012-11-01 00:00:00
abstract::The spinal cord injured patient has been the focus of clinical and research efforts to restore functional movement and obtain therapeutic benefits by electric stimulation of upper-motor-neuron paralyzed muscles. Our review articles treat developments in this field from 1983 to 1990. Efforts have been directed to resto...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To determine if a single, over-the-counter dose of the H1 antagonist chlorpheniramine maleate (CM) alters total peripheral resistance (TPR) and oxygen uptake (VO2) during submaximal exercise. DESIGN:The study was a prospective, longitudinal, double-blind, random crossover analysis of the cardiovascular and r...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0003-9993(98)90365-3
更新日期:1998-07-01 00:00:00
abstract::Traumatic brain injury (TBI) is often accompanied by additional trauma that can be obscured by cognitive dysfunction or multiple injuries in the same region of the body. This report describes the case of an unhelmeted motorcycle rider who collided with a telephone pole. He sustained a diffuse subarachnoid hemorrhage, ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1053/apmr.2001.26245
更新日期:2001-12-01 00:00:00
abstract:UNLABELLED:Pua Y-H, Cowan SM, Wrigley TV, Bennell KL. Discriminant validity of the Western Ontario and McMaster Universities Osteoarthritis Index Physical Functioning Subscale in community samples with hip osteoarthritis. OBJECTIVE:To evaluate, in a community hip osteoarthritis (OA) sample, the discriminant validity o...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2009.04.011
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To examine demographic, psychiatric symptom, and neuropsychological performance factors associated with duration of unemployment in Iraq/Afghanistan Veterans with a history of mild-to-moderate traumatic brain injury (TBI). DESIGN:Cross-sectional, secondary data analysis of baseline measures in a supported em...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2020.04.008
更新日期:2020-08-01 00:00:00
abstract::The functional effects of three types of therapy for subjects with long-term incomplete cervical spinal cord injuries were investigated. Men and women, aged 18 to 45 years, were assigned to one of four groups using a restricted randomization process. The training period was divided into two consecutive eight-week time...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-08-01 00:00:00
abstract:OBJECTIVE:To determine the safety and feasibility of percutaneous radiologic gastrostomy (PRG) tube placement in patients with amyotrophic lateral sclerosis (ALS) with too low a vital capacity to be weaned off noninvasive positive pressure ventilation (NPPV). DESIGN:Five-year follow-up cohort study. SETTING:Inpatient...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2008.12.006
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of an exergame-based intervention on a population sample of women with fibromyalgia. DESIGN:Single-blinded, randomized controlled trial with 8-week intervention. SETTING:Fibromyalgia center. PARTICIPANTS:Participants (all women) (N=83) were divided into 2 groups: an exercise group (...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.apmr.2017.02.011
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To quantify the initial deficit, change, and outcome in gait velocity during inpatient rehabilitation following stroke. DESIGN:The initial deficit on admission to rehabilitation was quantified by comparing 42 stroke patients with 42 controls matched by gender and age. The change in the stroke patients during...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(96)90072-6
更新日期:1996-10-01 00:00:00
abstract::The aims of this study were to examine effects of high-voltage stimulation (HVS) on wound closure, tensile properties, and mitotic activity. Thirty-six rabbits were assigned to experimental (n = 18) or control groups. Each animal was anesthetized and a full-thickness incision, 3.5 cm long, was made on its back. After ...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is a degenerative neurologic disease having both upper and lower motor neuron signs and symptoms. When the speech musculature is involved, a mixed dysarthria and dysphagia usually result. In a 49-year-old man with ALS, dysarthria and dysphagia progressed from mild to severe forms ov...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1979-09-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between foot pressures measured during level walking and other types of ambulatory activity in subjects with diabetes mellitus (DM) and peripheral neuropathy (PN). DESIGN:Descriptive survey with repeated measures. SETTING:University medical center. PARTICIPANTS:Convenience sample...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/j.apmr.2003.06.004
更新日期:2004-02-01 00:00:00
abstract::This research compared the performance of 20 individuals with global and mixed nonfluent aphasia across the four auditory comprehension subtests of the Boston Diagnostic Aphasia Examination (Word Discrimination, Body Part Identification, Commands, and Complex Ideational Material) and across the six subcomponents of th...
journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:
更新日期:1991-08-01 00:00:00