Abstract:
OBJECTIVES:To determine the relative and absolute reliability of the assessment of ambulatory walking activity during 2 consecutive weeks in patients with hematologic malignancies recovering at home from their medical treatment and to compare the physical activity level of hematologic cancer patients after high-dose chemotherapy with healthy subjects. DESIGN:Test-retest study of 2 consecutive 7-day recordings using the microprocessor-based step accelerometer 3 (SAM3). SETTING:Home and community. PARTICIPANTS:Patients (n=23) with hematologic malignancies recovering from high-dose chemotherapy and healthy controls (n=30). INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:The intraclass correlation coefficient (ICC(3,1)) and its 95% confidence interval (CI), SE of measurement procedure and its 95% CI, the smallest detectable difference (SDD), the coefficient of variation (CV), and t tests for the variables total steps and peak activity. RESULTS:The day-to-day and week-to-week CVs for walking activity and peak activity were 35.17% and 13.17% and 18.61% and 6.90%, respectively. For relative reliability, the ICCs for 2 consecutive 7-day recordings including the 95% CI for total steps and peak activity were 0.90 (95% CI, 0.75-0.98) and 0.85 (95% CI, 0.66-0.94), respectively. The absolute reliability for total steps and peak activity including the SE of measurement procedure and the 95% CI were 564 (95% CI, +/-1106) and 2.42 steps (95% CI, +/-4.74), respectively, for 2 consecutive 7-day recordings. The week-to-week SDD was 1564 for total steps and 6.70 for peak activity. The 7-day mean for total step activity was 5355 for the patients with hematologic malignancies and 6364 for healthy subjects (P<0.05). CONCLUSIONS:The results of this study indicate that there is good relative reliability for the assessment of 2 consecutive 7-day recordings of ambulatory walking activity, and it showed that the SDD derived from this sample may be useful in detecting changes in daily walking activity in hematologic cancer patients who are recovering from intensive medical treatment. The study also documented compromised levels of ambulatory walking activity among hematologic cancer patients recovering from high-dose chemotherapy as compared with healthy controls.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Knols RH,de Bruin ED,Aufdemkampe G,Uebelhart D,Aaronson NKdoi
10.1016/j.apmr.2008.06.020subject
Has Abstractpub_date
2009-01-01 00:00:00pages
58-65issue
1eissn
0003-9993issn
1532-821Xpii
S0003-9993(08)01495-0journal_volume
90pub_type
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journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,评审
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journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
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pub_type: 杂志文章,多中心研究
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journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
doi:10.1016/s0003-9993(97)90135-0
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,评审
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
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pub_type: 临床试验,杂志文章
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更新日期:2009-05-01 00:00:00
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更新日期:2013-01-01 00:00:00
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