Abstract:
:Fibromyalgia is a musculoskeletal disorder characterized by generalized myalgias, arthralgias widespread tender points in discreet areas on examination. It is frequently accompanied by fatigue, stiffness, and a nonrestorative sleep pattern. These patients generally have a normal blood count and chemistry profile. There is a subset of people with fibromyalgia (FM) who test positive for the antinuclear antibody (ANA) and have constitutional symptoms that resemble those of patients with early lupus. We studied the immunologic profile of patients with FM who are ANA-positive (+). A retrospective review of patient records in a university-based rheumatology practice was conducted. In a group of 66 FM patients, 30% (20) were ANA+, with a 75% preponderance of the speckled pattern and 20% diffuse pattern. The remaining 5% were equally split between diffuse-speckled and speckled-nucleolar patterns. All had negative staining for extractable nuclear antibodies. The Smart Index (SI), a ratio of the sedimentation rate to one-half the patient's age, was developed to characterize each patient's inflammatory response. The FM patients who were ANA negative (-) had a mean SI of 0.55, whereas the FM patient's who were ANA+ had a SI of 1.07. These ANA+ patients represent a subgroup of patients who have FM with an inflammatory response profile larger than that of the ANA-patients.
journal_name
Am J Phys Med Rehabiljournal_title
American journal of physical medicine & rehabilitationauthors
Smart PA,Waylonis GW,Hackshaw KVdoi
10.1097/00002060-199705000-00014subject
Has Abstractpub_date
1997-05-01 00:00:00pages
231-4issue
3eissn
0894-9115issn
1537-7385journal_volume
76pub_type
杂志文章abstract::Heterotopic ossification in the residual lower limb in an adult nontraumatic amputee patient.Heterotopic ossification usually occurs in association with various neurologic injuries, trauma, and burns. There have been few reports in the literature of heterotopic bone formation at the distal residual limb in the adult a...
journal_title:American journal of physical medicine & rehabilitation
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doi:10.1097/PHM.0b013e3181c5657c
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199603000-00003
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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doi:
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pub_type: 杂志文章,多中心研究
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更新日期:2012-02-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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doi:10.1097/00002060-199901000-00016
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journal_title:American journal of physical medicine & rehabilitation
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doi:10.1097/00002060-199308000-00011
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
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更新日期:2002-11-01 00:00:00
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
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更新日期:2007-01-01 00:00:00
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