Abstract:
OBJECTIVE:The aim of the study was to present the methodology, cohort demographics, and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA). DESIGN:The SPICA is based on the Swedish CArdioPulmonary BioImage Study, a study on cardiopulmonary diseases in a cohort of 30,000 people. The assessments in the SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and spinal cord injury-specific assessment tools. The inclusion criteria were as follows: age 50-65 yrs, traumatic spinal cord injury of 5 yrs or more, and injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C. RESULTS:Of 38 potential participants, 25 comprised the final sample (20% women, mean age 58 yrs, mean time since injury 28 yrs). Eight percent had sustained a cardiovascular event, and 72% were classified as a high risk for cardiovascular disease. Asthma was previously diagnosed in only 8%, and none had chronic obstructive pulmonary disease. CONCLUSIONS:The risk for cardiovascular disease in people with severe high-level spinal cord injury is a major clinical concern. Forthcoming studies in the SPICA will provide new knowledge of cardiopulmonary health in this cohort, which can guide future research and be used to develop long-term management.
journal_name
Am J Phys Med Rehabiljournal_title
American journal of physical medicine & rehabilitationauthors
Hill M,Jörgensen S,Engström G,Persson M,Lexell Jdoi
10.1097/PHM.0000000000001365subject
Has Abstractpub_date
2020-06-01 00:00:00pages
522-531issue
6eissn
0894-9115issn
1537-7385journal_volume
99pub_type
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e3182a51fc2
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
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doi:10.1097/PHM.0b013e31815e67d8
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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journal_title:American journal of physical medicine & rehabilitation
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