Intralesional corticosteroid therapy in proliferating head and neck hemangiomas: a review of 155 cases.

Abstract:

PURPOSE:The purpose of this paper is to review the effect of intralesional corticosteroid therapy in the treatment of 155 head and neck hemangiomas. METHODS:In the past 10 years, we have treated 155 proliferating head and neck hemangiomas with intralesional corticosteroid injections. Three to 6 injections of triamcinolone acetonide (10 mg/mL) in monthly intervals were given. Using slides and chart review, the results were assessed 1 month after completion of the treatment. RESULTS:Eighty-five percent of the lesions showed greater than 50% reduction in volume. Varied treatment response was noted in different classes of hemangioma. Eighty percent of the superficial, 75% of the deep, and 60% of the combined hemangiomas show more than 50% reduction in volume. Further growth was not found after treatment. The postinjection complication rate was 6.4% in this series. There were 2 patients with cushingoid appearance, 5 with cutaneous atrophy, and 3 suffered from anaphylactic shock. We found that lesions showing less than 50% reduction in volume were located mostly in the perioral area. CONCLUSIONS:Intralesional corticosteroid injections are safe and effective in arresting hemangioma proliferation. Superficial hemangiomas yield the best results.

journal_name

J Pediatr Surg

authors

Chen MT,Yeong EK,Horng SY

doi

10.1016/s0022-3468(00)90205-7

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

420-3

issue

3

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(00)90205-7

journal_volume

35

pub_type

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