Echocardiographic predictors of outcome in newborns with congenital diaphragmatic hernia.

Abstract:

OBJECTIVE:Despite new treatments, congenital diaphragmatic hernia (CDH) still has high mortality. The aim of this study was to identify echocardiographic predictors of outcome in newborns with an isolated CDH. METHODS:We reviewed medical charts and echocardiograms of 40 newborns who presented with CDH in the first 24 hours of life, from 1992 to 1996. We compared the cardiac valves and great arteries diameters, left-ventricular volume and mass, Apgar scores, and modified McGoon index (the combined diameter of hilar pulmonary arteries, indexed to the descending aorta) of survivors and nonsurvivors. We performed Student's t test and multiple logistic regression analysis between the 2 groups. RESULTS:Fourteen patients died 1 to 33 days after birth (median: 3 days), including 8 from progressive hypoxemia without operation; 26 have survived up to 5 years (median: 2 years) after successful operations. Nonsurvivors had significantly smaller diameters of right and left hilar pulmonary arteries, more frequent right-sided CDH, and lower mean Apgar scores at 1 and 5 minutes. The most significant prognostic factor was the modified McGoon index. A modified McGoon index

journal_name

Pediatrics

journal_title

Pediatrics

authors

Suda K,Bigras JL,Bohn D,Hornberger LK,McCrindle BW

doi

10.1542/peds.105.5.1106

subject

Has Abstract

pub_date

2000-05-01 00:00:00

pages

1106-9

issue

5

eissn

0031-4005

issn

1098-4275

journal_volume

105

pub_type

杂志文章
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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

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  • Socioeconomic Status and Long-term Outcomes in Single Ventricle Heart Disease.

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