Effect of glycine on cisplatin nephrotoxicity and heat-shock protein 70 expression in the rat kidney.

abstract：BACKGROUND:Interleukin 17 (IL-17) plays an important role in the pathogenesis of autoimmune diseases and might be associated with IgA nephropathy (IgAN). This study aimed to investigate the effect of IL-17 on autoimmune pathogenesis in IgA nephropathy. METHODS:DAKIKI cells were cultured and stimulated with IL-17 to pe...

journal_title：Renal failure

authors： Lin JR,Wen J,Zhang H,Wang L,Gou FF,Yang M,Fan JM

更新日期：2018-11-01 00:00:00

abstract：:The discoloration of effluent peritoneal dialysate, which is transparent in origin, is seen in some particular conditions including chyloperitoneum, calcium channel blocker usage, hemoperitoneum, perforated cholecystitis, iron administration, and hemorrhagic pancreatitis. We report a case of a 60-year-old woman who un...

journal_title：Renal failure

authors： Ling EK,Lin BS,Chiang SS,Tsai MH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Renal lymphangiectasia is rarely reported benign renal disorder of lymphatic malformation. Though found incidentally; it presents with nonspecific symptoms and shows characteristic findings in radiological imaging studies. AIM:Here, we report eight patients with symptoms, laboratory and imaging findings com...

journal_title：Renal failure

authors： Pandya VK,Sutariya HC,Gandhi SP,Khemchandani SI,Patel HV,Shah MK

更新日期：2017-11-01 00:00:00

abstract：:Increasing evidence suggests that circulating aldosterone per se contributes directly to renal and cardiovascular diseases. We sought to evaluate the effects of a three-month treatment with 25 mg spironolactone, an aldosterone receptor antagonist, on nephron function in 20 type II diabetic patients with persistent mic...

journal_title：Renal failure

authors： Ustundag A,Tugrul A,Ustundag S,Sut N,Demirkan B

更新日期：2008-01-01 00:00:00

abstract：:The clinical course of 15 patients with Wegener's granulomatosis (WG) and eight patients with microscopic polyangiitis (MPA) from one nephrological clinical center is presented for the period from 1984 to 1993, when testing for antineutrophil cytoplasmic antibodies (ANCA) was gradually introduced into routine clinical...

journal_title：Renal failure

authors： Schleiffer T,Burkhard B,Klooker P,Brass H

更新日期：1998-05-01 00:00:00

abstract：INTRODUCTION:Organic solvents are liquid substances commonly used in everyday life at home and in industrial workplaces. These solvents are found primarily in paint as thinner. Because other narcotics are hard to find, thinner is used as a narcotic especially among youngsters of low socioeconomic level. The aim of this...

journal_title：Renal failure

authors： Toros AB,Toros SZ,Aker F,Ersoz F,Derin A,Kesici B,Ozel L

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Morphine is an opioid analgesic drug often used for pain relief in cancer patients. However, there is growing evidence that morphine may modulate tumor growth, progression and metastasis. Unfortunately, the results obtained by these studies are still contradictory. METHODS:In this study, we investigated the...

journal_title：Renal failure

authors： Ma Y,Ren Z,Ma S,Yan W,He M,Wang D,Ding P

更新日期：2017-11-01 00:00:00

abstract：:During embryonic life, renal morphogenesis is characterized by a defined period of intense cellular activity, inductive-transformation of undifferentiated cells to polarized epithelia, in-growth of capillaries into an intricate parenchymal epithelial-mesenchymal mass, and finally the maturation into an organ with dive...

journal_title：Renal failure

authors： Wallner EI,Kumar A,Carone FA,Kanwar YS

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Although adequate peritoneal dialysis is not well defined, Kt/Vurea has been used as an index, and various values have been proposed. However, conflicting evidence existed regarding the appropriateness of using Kt/Vurea to define dialysis adequacy and its optimal value. Therefore, the present study performed...

journal_title：Renal failure

authors： Zhe XW,Shan YS,Cheng L,Tian XK,Wang T

更新日期：2007-01-01 00:00:00

abstract：:The prognosis of uremia patients on continuous ambulatory peritoneal dialysis (CAPD) is related to frequent peritonitis rate. Frequent peritonitis will lead to peritoneum failure, making CAPD unfeasible. We have performed proteomic profiling of peritoneal dialysis effluent samples from a cross-section of CAPD patients...

journal_title：Renal failure

authors： Lin WT,Tsai CC,Chen CY,Lee WJ,Su CC,Wu YJ

更新日期：2008-01-01 00:00:00

abstract：:In kidney disease, inflammation and lipid dysmetabolism are often associated together, however, the effect and mechanism of inflammatory mediators and lipid dysmetabolism on kidney damage is still unclear. In this study, Wistar rats were randomized into four groups: normal diet + saline (Group N), high-fat diet (HF)+ ...

journal_title：Renal failure

authors： Wang Z,Huang W,Li H,Tang L,Sun H,Liu Q,Zhang L

更新日期：2018-11-01 00:00:00

abstract：:We evaluated amount and composition of amino acids in supplementation of hyperalimentation from the standpoint of whether it may improve nutrition and/or reduce the indexes of uremia such as BUN. Rats with established uremia, by 5/6 nephrectomy, were treated with various isocaloric solutions containing different amoun...

journal_title：Renal failure

authors： Kikuchi T,Tanaka H,Kokuba Y,Sato M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:We aimed to evaluate whether serum apelin could reflect the nutritional status of children on dialysis. METHODS:Twelve patients on peritoneal dialysis (PD) and 20 patients on hemodialysis (HD) were enrolled. Patients received individualized diet for six months. Anthropometric and laboratory indices were mea...

journal_title：Renal failure

authors： Yavuz S,Cetinkaya S,Anarat A,Bayazıt AK

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Acquired cystic kidney disease (ACKD) is a frequent complication in chronic hemodialysis (HD) patients and a risk factor for renal cell carcinoma. Online hemodiafiltration (HDF) provides better clearance of middle molecular weight solutes, but its effect on ACKD has not been investigated. MATERIALS AND METH...

journal_title：Renal failure

authors： Weng CJ,Chang MY,Chen YC,Tian YC,Fang JT,Yang CW

更新日期：2009-01-01 00:00:00

abstract：:Creatol (CTL) is a hydroxyl radical adduct of creatinine (Cr). The serum methylguanidine (MG) level and the MG/Cr molar ratio are reported to be biomarkers for oxidative stress. The aim of this study was to examine whether urinary excretion of CTL, another oxidative stress-related marker, is increased in patients with...

journal_title：Renal failure

authors： Ienaga K,Nakamura K,Fujisawa T,Fukunaga Y,Nihei H,Narita M,Tomino Y,Sanaka T,Aoyagi K,Nakano K,Koide H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) and chronic kidney disease (CKD) are serious medical conditions with significant morbidity and mortality and often coexist. Because of perioperative risks in these patients, they may not be considered a candidate for renal transplantation (RTx). MATERIAL AND METHODS:We compare re...

journal_title：Renal failure

authors： Kute VB,Vanikar AV,Patel HV,Gumber MR,Shah PR,Engineer DP,Balwani MR,Gautam RS,Modi PR,Shah VR,Trivedi HL

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Acute hyperammonemia caused by urea cycle disorder is a medical emergency for which immediate managements should be taken to minimize permanent brain damage. Among different enzyme defects, ornithine transcarbamylase deficiency (OTC) is one of the most common enzyme defect in urea cycle disorders. We utilize...

journal_title：Renal failure

authors： Chen CY,Chen YC,Fang JT,Huang CC

更新日期：2000-11-01 00:00:00

abstract：:The derangements in bone metabolism in patients with chronic renal failure (CRF) are summarized as uremic bone disease (UBD). In this study, we planned to determine the serum prolidase to compare it with the other biochemical markers. This study was performed on 44 patients (19 females, 25 males, mean age = 56.8 +/- 1...

journal_title：Renal failure

authors： Evrenkaya TR,Atasoyu EM,Kara M,Unver S,Gultepe M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Hypertension very often accompanies progression of chronic kidney disease (CKD) in children. A cross-sectional analysis of hypertension prevalence in dialyzed children in Poland was designed with a comparison with the data previously recorded 10 years earlier. METHODS:Two cohorts of children were analyzed: ...

journal_title：Renal failure

authors： Tkaczyk M,Stańczyk M,Miklaszewska M,Zachwieja K,Wierciński R,Stankiewicz R,Firszt-Adamczyk A,Zachwieja J,Borzęcka H,Zagożdżon I,Leszczyńska B,Medyńska A,Adamczyk P,Szczepańska M,Fendler W

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with markedly increased cardiovascular (CV) risk. This increase is not fully explained by traditional CV risk factors but may in part be mediated by nontraditional risk factors, such as inadequate vitamin D (vit D) levels and insulin resistance (IR). Although IR is ...

journal_title：Renal failure

authors： Lai S,Coppola B,Dimko M,Galani A,Innico G,Frassetti N,Mariotti A

更新日期：2014-02-01 00:00:00

abstract：:The ability to predict the rate of progression of renal parenchymal disease may help in its clinical management. We undertook characterization of urinary macrophages obtained from patients with various renal diseases paying special attention to the differentiation from non-progressive to progressive renal diseases. A ...

journal_title：Renal failure

authors： Hotta O,Kitamura H,Taguma Y

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Spontaneous crescentic glomerulonephritis (SCG)/Kj mice are a candidate for suitable animal model of human pauci-immune crescentic glomerulonephritis (GN). In the present study, we used renal biopsy technique and analyzed time sequence correlations among crescent formation and glomerular neutrophil infiltrat...

journal_title：Renal failure

authors： Miyazawa S,Saiga K,Nemoto K,Mae T,Hotta O

更新日期：2002-09-01 00:00:00

abstract：:Atrial Natriuretic Peptide (ANP), has protective effect on the outcome of acute renal failure in animals when infused over short periods of time. Escherichia Coli heat-stable enterotoxin (STa) acts on a particulate guanylate cyclase receptors leading to an increase in cytosolic cGMP similar to ANP. STa has longer dura...

journal_title：Renal failure

authors： Abdulla HM

更新日期：2000-01-01 00:00:00

abstract：:Studies were performed to reexamine the response of erythropoietin (Epo) production to acute hypoxic stimuli in patients with end-stage renal disease (ESRD). In the absence of acute bleeding or hypoxia, the serum Epo level in ESRD was similar to that of normal subjects despite severe anemia. In 11 dialysis patients wi...

journal_title：Renal failure

authors： Kato A,Hishida A,Kumagai H,Furuya R,Nakajima T,Honda N

更新日期：1994-01-01 00:00:00

abstract：:In the present study, we investigated the protective effect of Withania somnifera, an indigenous medicinal herb used in ayurvedic traditional systems for more than 3000 years in India, on gentamicin (GEN)-induced nephrotoxicity. The root extract of three different doses of W. somnifera (viz., 250, 500, and 750 mg/kg) ...

journal_title：Renal failure

authors： Jeyanthi T,Subramanian P

更新日期：2009-01-01 00:00:00

abstract：:Aldosterone is reported to promote fibrosis of multiple organs. Recent studies showed that Na+-H+ exchanger isoform 1 (NHE1) was involved in mineralocorticoid-induced tissue fibrosis. The present study examined the role of NHE1 in aldosterone-induced glomerulosclerosis in rats. SD male rats were subjected to 5/6 nephr...

journal_title：Renal failure

authors： Zhang M,Chen J,Liu S,You L,Lin S,Gu Y

更新日期：2009-01-01 00:00:00

abstract：AIM:Returning to society plays an important role in improving the quality of life in maintenance hemodialysis (MHD) patients, and retention of employment is one of the core enablers. The study is to assess the employment status and to determine the variables for unemployment in Chinese MHD patients. METHODS:Prevalent ...

journal_title：Renal failure

authors： Huang B,Lai B,Xu L,Wang Y,Cao Y,Yan P,Chen J

更新日期：2017-11-01 00:00:00

abstract：AIM:To investigate the effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats and the feasibility of lentivirus-mediated shRNA delivery through renal parenchyma injection. METHODS:Anti-collagen type I shRNA lentiviral vector was constructed, and rat mesangial cells were transfect...

journal_title：Renal failure

authors： Zhou C,Shan Y,Zhao H,He P

更新日期：2011-01-01 00:00:00

abstract：:Kidney biopsy is an investigation for diagnosis and prognosis of a variety of nephritides. It also influences therapeutic options. Immunofluorescence (IMF) greatly adds in identifying the pathologies which may not be obvious on light microscopy (L/M), such as IgM, IgA nephropathy, pauci-immune glomerulonephritis, and ...

journal_title：Renal failure

authors： Ali A,Ali MU,Ali MA

更新日期：2011-01-01 00:00:00

abstract：:Amidinotransferase (transamidinase, L-arginine: glycine amidinotransferase, EC 2.1.4.1) is an enzyme that catalyses the first step in creatine synthesis primarily in the kidney and pancreas. The kidney is also the primary target organ for the toxic effect of mercury. Therefore, we studied the effect of acute uremic sy...

journal_title：Renal failure

authors： Nikolic J,Sokolovic D

更新日期：2004-11-01 00:00:00