Clinical experience with prazosin in hypertension.

Abstract:

:Twenty of 24 hypertensive patients, six of whom had severe disease, had a reduction in standing blood pressure to less than 140/90 mm Hg after six weeks of treatment with prazosin alone or prazosin plus other antihypertensive drugs. The absence of significant side effects was impressive.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Turner AS,Watson OF,Peel JO

subject

Has Abstract

pub_date

1975-11-01 00:00:00

pages

88-92

eissn

0032-5481

issn

1941-9260

journal_volume

Spec No

pub_type

临床试验,杂志文章
  • Thyroid function tests. Guidelines for interpretation in common clinical disorders.

    abstract::While a wide variety of thyroid function tests are currently available, all are sometimes abnormal in patients without thyroid disease. To interpret test results properly, the clinician needs to be aware of factors altering thyroid function tests. In every instance, the clinician needs to begin by asking whether the p...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: de los Santos ET,Mazzaferri EL

    更新日期:1989-04-01 00:00:00

  • The kidney and type 2 diabetes mellitus: therapeutic implications of SGLT2 inhibitors.

    abstract::Understanding the role of the kidneys in type 2 diabetes mellitus (T2DM) has taken on an increased importance in recent years with the arrival of sodium-glucose co-transporter 2 (SGLT2) inhibitors - antihyperglycemic agents (AHAs) that specifically target the kidneys. This review includes an update on the physiology o...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2016.1147926

    authors: Weir MR

    更新日期:2016-01-01 00:00:00

  • Rapid evaluation of comatose patients.

    abstract::Coma is a common, life-threatening medical problem encountered by primary care physicians. The principles of emergency management mandate that adequate oxygenation, blood flow, and supplementation with thiamine and glucose be given to the brain before a thorough diagnostic evaluation is undertaken. Knowledge of the us...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11716346

    authors: Alguire PC

    更新日期:1990-05-01 00:00:00

  • Aggressive treatment of acute myocardial infarction. Management options for various settings.

    abstract::Multiple lifesaving options are currently available for treatment of acute myocardial infarction as a medical emergency. Serial electrocardiography and continuous ST-segment monitoring, urgent echocardiography, rapid enzyme analysis, and cardiac catheterization may all assist in the accurate and early diagnosis of acu...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11945769

    authors: Kahn JK,Cragg DR,Almany SL,Ajluni SC

    更新日期:1993-12-01 00:00:00

  • Emergency care of chemical burns.

    abstract::Because of the large number of potentially injurious chemicals present in the home and workplace, chemical burns pose a unique challenge to the health care professional. For the majority of injuries, prompt and prolonged hydrotherapy is the cornerstone of therapy. The clinician needs to remember that the extent and de...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11699164

    authors: Fitzpatrick KT,Moylan JA

    更新日期:1985-10-01 00:00:00

  • Bronchiectasis: the 'other' obstructive lung disease.

    abstract::Bronchiectasis belongs to the family of chronic obstructive lung diseases, even though it is much less common than asthma, chronic bronchitis, or emphysema. Clinical features of these entities overlap significantly. The triad of chronic cough, sputum production, and hemoptysis always should bring bronchiectasis to min...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1999.07.607

    authors: Mysliwiec V,Pina JS

    更新日期:1999-07-01 00:00:00

  • Stress-related disorders. Recent developments in hospital treatment.

    abstract::The stress treatment program at Ochsner, New Orleans, provides participants with knowledge of necessary skills and opportunities for rehearsal and practice within the setting. In addition, the modalities chosen reinforce what Lazarus and Opton described as "perceived control," which was found to be as instrumental as ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11698991

    authors: Wakeman RJ,Mestayer RF 3rd

    更新日期:1985-05-01 00:00:00

  • Physician adherence to ACR gout treatment guidelines: perception versus practice.

    abstract:BACKGROUND:In October 2012, the American College of Rheumatology (ACR) published recommendations for chronic gout treatment goals and pharmacotherapy. OBJECTIVES:Identify potential gaps between real-world chronic gout treatment, ACR guideline recommendations, and physicians' perceived guideline adherence by evaluating...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2014.05.2774

    authors: Oderda GM,Shiozawa A,Walsh M,Hess K,Brixner DI,Feehan M,Akhras K

    更新日期:2014-05-01 00:00:00

  • Treatment of postprandial hyperglycemia in type 2 diabetes.

    abstract::Healthcare providers usually assess glycemic control in diabetic patients by measuring fasting plasma glucose and preprandial glucose levels, as well as hemoglobin A1c (HbA1c). Evidence now suggests that elevated postprandial glucose concentrations may contribute to suboptimal glycemic control. Several medications and...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.12.2001.suppl17.93

    authors: Fasy EA,Buse JB

    更新日期:2001-12-01 00:00:00

  • Reversal agents in development for the new oral anticoagulants.

    abstract::The new oral anticoagulants have many advantages over vitamin K antagonists, but they are still associated with a troublesome incidence of major bleeding. Additionally, the absence of a reversal agent for the new oral anticoagulants is a barrier to their more widespread use. Currently, there are 3 potential reversal a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2014.11.2829

    authors: Costin J,Ansell J,Laulicht B,Bakhru S,Steiner S

    更新日期:2014-11-01 00:00:00

  • Raising the curtain on cancer. Is the puzzle finally becoming clear?

    abstract::Looking back at the long history of cancer, we can still relate to that POSTGRADUATE MEDICINE editorial written 50 years ago: "None of the basic problems of cancer has been solved. The death rate is constantly mounting. Small wonder that many doctors face cancer with a pessimism bordering on resignation." The temptati...

    journal_title:Postgraduate medicine

    pub_type: 历史文章,杂志文章

    doi:10.3810/pgm.1997.09.307

    authors: Harpham WS,Hoel D

    更新日期:1997-09-01 00:00:00

  • Diabetic diarrhea. An underdiagnosed complication?

    abstract::Diarrhea is a common gastrointestinal problem in diabetes, and its prevalence has been underestimated. The cause of diabetic diarrhea is unknown, but it is probably related to gastrointestinal motility disturbances secondary to diabetic autonomic neuropathy. Other causes (especially primary malabsorption syndromes and...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1992.11701372

    authors: Beebe DK,Walley E

    更新日期:1992-06-01 00:00:00

  • A checklist for evaluation of HIV-infected patients.

    abstract::To aid in making care of HIV-infected patients part of your office routine, Dr Coodley presents here a checklist that combines the various clinical aspects of initial management. Covering the steps from the history to plans for follow-up, this article should allay anxiety and promote confidence in your entire staff by...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11701640

    authors: Coodley GO

    更新日期:1993-03-01 00:00:00

  • Weight considerations in psychotropic drug prescribing and switching.

    abstract::Our review describes potential weight-altering effects of psychotropic medications (antipsychotics, antidepressants, anti-anxiety medications, mood stabilizers, sedative-hypnotics, medications for attention-deficit/hyperactivity disorder, and other psychotropic medications) and offers guidance on switching a medicatio...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2013.09.2706

    authors: Hasnain M,Vieweg WV

    更新日期:2013-09-01 00:00:00

  • PDI-4A: an augmented provisional screening instrument assessing 5 additional common anxiety-related diagnoses in adult primary care patients.

    abstract::Patients with nonpsychotic mental health and emotional problems are commonly seen by primary care physicians. The objective of this study was to expand the Provisional Diagnostic Instrument-4 (PDI-4) to include a short self-report screen for 5 common anxiety-related diagnoses: panic attack (PA), social phobia (SP), ob...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2011.09.2463

    authors: Houston JP,Kroenke K,Davidson JR,Adler LA,Faries DE,Ahl J,Swindle R,Trzepacz PT

    更新日期:2011-09-01 00:00:00

  • Blood-loss anemia.

    abstract::Effective management of blood-loss anemia depends on an understanding of the physiologic response to volume loss, the pattern of marrow response to acute depletion of red cell mass, and the controlling influence of iron supply. Each of these elements must be evaluated and incorporated into the plan of management. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1978.11714948

    authors: Hillman RS

    更新日期:1978-10-01 00:00:00

  • Colorectal carcinoma: overview of management techniques.

    abstract::The fact that the national death rate from carcinoma of the colon and rectum has remained static over the past two decades is strong incentive for future investigation of measures to allow detection in its early and more favorable stage. Although no significant improvements in surgical techniques have afforded improve...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1979.11715249

    authors: Bland KI,Garrison RN,Knutson CO

    更新日期:1979-09-01 00:00:00

  • Evaluation of a first seizure. Is it epilepsy?

    abstract::The first step in evaluation of a presumed seizure is to determine whether the event was indeed a seizure and which diagnostic studies are needed. The second step is to correctly diagnose the seizure on the basis of the medical history and findings from the physical, neurologic, and laboratory evaluation. The third st...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2002.01.1074

    authors: Prego-Lopez M,Devinsky O

    更新日期:2002-01-01 00:00:00

  • Controversies in resuscitation.

    abstract::Many controversies, only a few of which have been discussed here, are now raging in the field of resuscitation. Much is expected to change in the next five to ten years. The American Heart Association is now considering changes for its new advanced cardiac life support course, which should be ready this year. The cour...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699404

    authors: Hankins DG

    更新日期:1986-05-15 00:00:00

  • The place of inhaled corticosteroids in the treatment of chronic obstructive pulmonary disease: a narrative review.

    abstract::Inhaled corticosteroids (ICSs) belong to the armament for treatment of chronic obstructive pulmonary disease (COPD) and as such, they are widely used in real life. This is a narrative review on evidence-based papers published in the English language listed in Medline between 1990 and March 2016 discussing ICS applicat...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2016.1186487

    authors: Andreeva-Gateva PA,Stamenova E,Gatev T

    更新日期:2016-06-01 00:00:00

  • Coronary revascularization in multivessel disease. Which is better, stents or surgery?

    abstract::Coronary artery disease (CAD) remains the major cardiovascular health issue in contemporary clinical practice. Treatment options for multivessel CAD include medical therapy, percutaneous coronary intervention (PCI), and coronary artery bypass grafting (CABG). Here, the authors review the most recent data that compare ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2005.12.1670

    authors: Almeda FQ,Snell RJ

    更新日期:2005-12-01 00:00:00

  • Principles of therapeutic drug monitoring.

    abstract::Biochemical monitoring is generally advised for drugs that are potentially toxic, have a narrow therapeutic range, or are prescribed for life-threatening disease. Monitoring should not be attempted until the serum concentration reaches a plateau, or steady state, and sampling must be timed carefully. Besides incorrect...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1981.11715801

    authors: Burke MD

    更新日期:1981-07-01 00:00:00

  • Managing type 2 diabetes: balancing HbA1c and body weight.

    abstract::Most patients with type 2 diabetes present with comorbid overweight or obesity. Reaching and maintaining acceptable glycemic control is more difficult in overweight and obese patients, and these conditions are associated with increased risk for cardiovascular and other diseases. Glycemic management for these patients ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2010.05.2148

    authors: Mavian AA,Miller S,Henry RR

    更新日期:2010-05-01 00:00:00

  • Nephrolithiasis: how it happens and what to do about it.

    abstract::Nephrolithiasis is caused by several biochemical mechanisms, identification of which allows specific therapy that may prevent recurrences. In patients with their first kidney stone, careful evaluation is needed to identify those at highest risk for recurrence. Extensive evaluation of this subgroup should lead to prope...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1996.12.127

    authors: Trivedi BK

    更新日期:1996-12-01 00:00:00

  • Laboratory tests for rheumatic diseases.

    abstract::A carefully taken history and thorough physical examination remain the most crucial aspects of diagnosing rheumatic disorders. Non-rheumatologic conditions also need to be kept in mind. Laboratory tests should be looked on as mostly supportive or confirmatory, because many of the tests are relatively nonspecific and m...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1991.11700818

    authors: Yancey WB Jr,Williams RC Jr

    更新日期:1991-02-01 00:00:00

  • Life-threatening neck infections. Early diagnosis to forestall crisis.

    abstract::Infections of the neck become life-threatening with airway or systemic involvement. The first step in successful management is early recognition by the initial examiner. Patient evaluation includes a thorough history and physical examination, laboratory studies, and if the patient's condition is stable, roentgenograph...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1984.11698815

    authors: Beck HJ,McCaffrey TV

    更新日期:1984-12-01 00:00:00

  • Progressive congestive heart failure. Ways to approach office management.

    abstract::Treatment of congestive heart failure depends on the cause, precipitating factors, and symptoms of the disease in each patient. Dr Kahn outlines the use of the three main types of pharmacologic agents given for heart failure--diuretics, vasodilators, and digoxin. He describes a stepwise regimen, whereby agents are add...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1991.11700920

    authors: Kahn JK

    更新日期:1991-05-01 00:00:00

  • Allergic disease in children. Guide to diagnosis and treatment.

    abstract::Allergy is responsible for many problems in the pediatric age-group. At times the most difficult job for the physician is to determine if the patient is indeed allergic and, if so, to what. Allergy skin testing remains the first choice for diagnostic study. Treatment consists of avoiding the offending allergen if poss...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1984.11716317

    authors: Hein EW,Kishore R

    更新日期:1984-05-01 00:00:00

  • Milk-alkali syndrome. A consequence of chronic antacid abuse.

    abstract::The case described here illustrates the need to consider milk-alkali syndrome in the differential diagnosis of hypercalcemia, even in this age of histamine2 blockers and mucosal protectors. Thorough history taking and gastrointestinal workup help rule out alternative causes of hypercalcemia, such as cancer, hyperparat...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1993.11701690

    authors: Newmark K,Nugent P

    更新日期:1993-05-01 00:00:00

  • Brain failure in older patients. Uncovering treatable causes of a diminished ability to think.

    abstract::The term "brain failure" implies only dysfunction of a major organ system, not that an exact diagnosis has been made. Assessment and treatment of older patients with diminished cognitive ability can be challenging; however, the experience can also be extremely rewarding when a reversible condition is alleviated and th...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Paist SS 3rd,Martin JR

    更新日期:1996-05-01 00:00:00