Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats.

abstract：:Hypertension is a common finding among obstructive sleep apnea (OSA) patients, and is thought to be caused by sympathetic hyperactivity. The present study compares the contributions of the respiratory disturbance index (RDI) as a reflection of sleep fragmentation, and the magnitude of oxygen desaturation, to sympathet...

journal_title：American journal of hypertension

authors： Peled N,Greenberg A,Pillar G,Zinder O,Levi N,Lavie P

更新日期：1998-11-01 00:00:00

abstract：:Leptin, the gene product of the ob gene, is influenced by gender and insulin sensitivity. Because in human hypertension there are important endocrine-hemodynamic gender-dependent differences, we compared plasma leptin in 39 essential hypertensives (EH) and in 27 normotensive healthy subjects (HS) matched for gender, a...

journal_title：American journal of hypertension

authors： Mallamaci F,Cuzzola F,Tripepi G,Cutrupi S,Parlongo S,Tripepi R,Zoccali C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Remnant-like lipoprotein particle cholesterol (RLP-C) is a highly atherogenic factor. RLP-C induces endothelial dysfunction and is associated with hyperinsulinemia. This study was designed to determine whether high plasma RLP-C levels predispose to the development of hypertension in subjects with normal bloo...

journal_title：American journal of hypertension

authors： Kasahara A,Adachi H,Hirai Y,Enomoto M,Fukami A,Yoshikawa K,Esaki E,Yokoi K,Ogata K,Tsukagawa E,Obuchi A,Yoshimura A,Nakamura S,Imaizumi T

更新日期：2013-06-01 00:00:00

abstract：:Medical literature that has coalesced during the past two to three decades has identified adequate intake of nutrients from dairy foods as a common factor in the reduction of the disease burden of several common medical conditions. These include obesity, hypertension, type 2 diabetes, osteoporosis, kidney stones, cert...

journal_title：American journal of hypertension

authors： McCarron DA,Heaney RP

更新日期：2004-01-01 00:00:00

abstract：:Renal artery stent placement has been shown to improve blood pressure (BP) and stabilize renal function in patients with atherosclerotic renovascular disease. However, limited data are available in patients > or = 75 years of age. We analyzed the prestent characteristics and clinical outcomes of patients aged > or = 7...

journal_title：American journal of hypertension

authors： Bloch MJ,Trost DA,Whitmer J,Pickering TG,Sos TA,August P

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Physical activity (PA) has been associated with decreased left ventricular (LV) hypertrophy in previous studies. However, little is known about the relationship between PA and LV structure and factors which influence this relationship among African Americans. METHODS:We evaluated 1,300 African Americans wit...

journal_title：American journal of hypertension

authors： Kamimura D,Loprinzi PD,Wang W,Suzuki T,Butler KR,Mosley TH,Hall ME

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The mechanism of left atrial (LA) remodeling is poorly understood. The aim of this longitudinal study was to investigate whether changes in NT-proBNP levels relate to alterations of LA structure and function over time in a multi-ethnic population. METHODS:From the prospective cohort study, the Multi-Ethnic ...

journal_title：American journal of hypertension

authors： Varadarajan V,Ambale-Venkatesh B,Hong SY,Habibi M,Ashikaga H,Wu CO,Chen LY,Heckbert SR,Bluemke DA,Lima JAC

更新日期：2021-01-25 00:00:00

abstract：BACKGROUND:We investigated the effects of percutaneous transluminal renal angioplasty on left ventricular (LV) mass, and the impact of LV mass reduction on outcomes. METHODS:A total of 144 hypertensive patients with renal artery stenosis (RAS) (mean age 69 years; 22.2% fibromuscular dysplasia (FMD)) who underwent angi...

journal_title：American journal of hypertension

authors： Iwashima Y,Fukuda T,Horio T,Kusunoki H,Hayashi SI,Kamide K,Kawano Y,Ishimitsu T,Yoshihara F

更新日期：2020-05-21 00:00:00

abstract：:The results of 19 antihypertensive treatment trials spanning some 20 years of research showed that treatment had significant benefits for pressure-related complications of hypertension but generally did not prevent coronary artery disease morbidity or mortality. As possible reasons for this relative failure were explo...

journal_title：American journal of hypertension

authors： Rosenman RH

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:As a serious pregnancy-specific condition, preeclampsia (PE) is a serious pregnancy-specific condition characterized by insufficient trophoblastic invasion and shallow placental implantation. Long noncoding RNA uc.187, which is transcribed from an ultra-conserved region is highly expressed in the placental t...

journal_title：American journal of hypertension

authors： Huang J,Qian Y,Cheng Q,Yang J,Ding H,Jia R

更新日期：2020-04-29 00:00:00

abstract：OBJECTIVES:Central blood pressure (BP) can be used to define hypertension. A central BP approach may be more sensitive than a conventional brachial BP approach in detecting hypertension. We aimed to compare the 2 approaches in estimating the prevalence hypertension in a nationally representative population. METHODS:A ...

journal_title：American journal of hypertension

authors： Chuang SY,Chang HY,Cheng HM,Pan WH,Chen CH

更新日期：2018-02-09 00:00:00

abstract：BACKGROUND:The adverse association between blood pressure and carotid artery intima-media thickness (IMT), a surrogate measure of subclinical atherosclerosis, is well-known. However, whether the G-6A polymorphism of the angiotensinogen (AGT) gene, a candidate gene of hypertension and vascular remodeling, modulates this...

journal_title：American journal of hypertension

authors： Bhuiyan AR,Chen W,Srinivasan SR,Rice J,Mock N,Tang R,Bond MG,Boerwinkle E,Berenson GS

更新日期：2007-10-01 00:00:00

abstract：:The benzothiazepine calcium channel antagonist diltiazem is a short-acting drug. To achieve effective 24-h blood pressure control with once-daily dosing, it relies on various extended drug-delivery systems that have grown in importance as a result of the recent reports relating the use of short-acting calcium channel ...

journal_title：American journal of hypertension

authors： Smith DH,Neutel JM,Weber MA

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:There may be a link among stress, adrenal medullary activation, and the development of hypertension. Obesity is characterized by sympathetic activation and predisposes to hypertension, but may be associated with low or normal adrenal medullary activity. We hypothesized that plasma epinephrine (E) levels and ...

journal_title：American journal of hypertension

authors： Reims HM,Fossum E,Høieggen A,Moan A,Eide I,Kjeldsen SE

更新日期：2004-07-01 00:00:00

abstract：:The treatment of diseases has been based on the concept of homeostasis and has not incorporated an understanding of biologic rhythms and their underlying mechanisms. Biologic rhythms are implicated in cardiovascular events. Failure to recognize the circadian decline in blood pressure may result in iatrogenic chronopat...

journal_title：American journal of hypertension

authors： Prisant LM

更新日期：2001-09-01 00:00:00

abstract：:Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide and regulator of blood flow that plays an important role in blood pressure (BP) elevation in some models of experimental hypertension such as DOCA-salt rat, DOCA-salt-treated spontaneously hypertensive rats (SHR), stroke-prone SHR, Dahl salt-sensitive rats, ang...

journal_title：American journal of hypertension

authors： Schiffrin EL

更新日期：2001-06-01 00:00:00

abstract：:It has been suggested that atheroma formation is a chronic inflammatory response to lipid-derived inflammatory mediators accumulating at selected arterial sites. At large artery flow dividers and curvatures, secondary flow phenomena create zones of stagnation and recirculation that deprive endothelial cells of shear s...

journal_title：American journal of hypertension

authors： Henry PD,Chen CH

更新日期：1993-11-01 00:00:00

abstract：:The renin-angiotensin-aldosterone system plays a major role in the pathogenesis of hypertension by enhancing the production or the activity of angiotensin II (ANG II). We evaluated the effects of hormone replacement therapy (HRT) on the renin-angiotensin-aldosterone system and on bradykinin in postmenopausal women (PM...

journal_title：American journal of hypertension

authors： Umeda M,Ichikawa S,Kanda T,Sumino H,Kobayashi I

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Despite an association between visit-to-visit blood pressure (BP) variability (VV-BPV) and cardiovascular (CV) outcomes, many studies performed during the past 4 years have shown conflicting results. This study investigated the impact of VV-BPV on CV outcomes in the Korean National Health Insurance Service (...

journal_title：American journal of hypertension

authors： Choi S,Shin J,Choi SY,Sung KC,Ihm SH,Kim KI,Kim YM

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) and left ventricular (LV) hypertrophy are considered to be closely associated. However, the relationship has not yet been fully demonstrated and is hence still controversial. The purpose of this study was to assess in hypertensive male patients the relationship between OSA and c...

journal_title：American journal of hypertension

authors： Yamaguchi T,Takata Y,Usui Y,Asanuma R,Nishihata Y,Kato K,Shiina K,Yamashina A

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:There is evidence from genome wide association study that single-nucleotide polymorphisms (SNPs) in the 5' end of the uromodulin gene (UMOD) affect uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb of the loop of Henle (TAL) and its effect on...

journal_title：American journal of hypertension

authors： McCallum L,Brooksbank K,McConnachie A,Aman A,Lip S,Dawson J,MacIntyre IM,MacDonald TM,Webb DJ,Padmanabhan S

更新日期：2020-10-21 00:00:00

abstract：:It has been speculated for some time that various antihypertensive medications may have a deleterious effect on respiration during sleep and thereby enhance the apparent association between hypertension and sleep apnea/hypopnea (SAH). However, there are few data to support this contention. The present study used a dou...

journal_title：American journal of hypertension

authors： Bartel PR,Loock M,Becker P,Robinson E,van der Meyden C,Rossouw S

更新日期：1997-06-01 00:00:00

abstract：:Cultured vascular smooth muscle cells (VSMCs) of the spontaneously hypertensive rat (SHR) show a higher density (Bmax) of ANP receptors and a blunted cyclic (c) GMP response to the hormone. To explore the idea that a higher cytosolic free Ca2+ (Cai2+) may be responsible for a blunted cGMP response to ANP, we examined ...

journal_title：American journal of hypertension

authors： Nakamura M,Nakamura A,Hatori N,Fine BP,Aviv A

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Functional status may be useful for identifying older adults who benefit from lower blood pressure. We examined whether functional status modifies the effect of antihypertensive treatment among older adults. METHODS:Post hoc analyses of the Systolic Hypertension in the Elderly Program (SHEP), a randomized t...

journal_title：American journal of hypertension

authors： Charlesworth CJ,Peralta CA,Odden MC

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Differences between the antihypertensive responses to drug therapy measured by office blood pressure (OBP) and ambulatory blood pressure monitoring (ABPM) techniques have been noted but rarely analyzed. We studied whether the OBP and 24-h ABPM responses to hydrochlorothiazide differ and, if so, the relevance...

journal_title：American journal of hypertension

authors： Finkielman JD,Schwartz GL,Chapman AB,Boerwinkle E,Turner ST

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:To clarify whether the double product (DP) (product of systolic blood pressure (SBP) and pulse rate (PR)) at rest based on home blood pressure (HBP) measurement has prognostic value for mortality. METHODS:HBP data of 2,583 participants from a Japanese general population (40% men) ≥35 years of age (mean, 59 ...

journal_title：American journal of hypertension

authors： Inoue R,Ohkubo T,Kikuya M,Metoki H,Asayama K,Kanno A,Obara T,Hirose T,Hara A,Hoshi H,Totsune K,Satoh H,Kondo Y,Imai Y

更新日期：2012-05-01 00:00:00

abstract：:Responses of renin release and blood pressure to aspirin DL-lysine (ASP) were examined to find out if the responses could help in the differentiation between unilateral renovascular hypertension (RVH) and hyperreninemic essential hypertension (EHT). The two studies involved ten patients with unilateral RVH, eight with...

journal_title：American journal of hypertension

authors： Imanishi M,Ohta M,Kawamura M,Akabane S,Matsushima Y,Kuramochi M,Kojima S,Kimura K,Takamiya M,Ito K

更新日期：1991-09-01 00:00:00

abstract：:Understanding the causes and treatment of chronic hypotension is of benefit to affected patients and may also shed light on the physiology and genetics of mechanisms of blood pressure control. Symptomatic hypotension (almost always with a blood pressure fall greater than or equal to 20/10 mm Hg) may reflect unrecogniz...

journal_title：American journal of hypertension

authors： Robertson D,Mosqueda-Garcia R,Robertson RM,Biaggioni I

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:The prevalence of hypertension in the Middle East is not well defined. We examined the prevalence, awareness, treatment, and control of hypertension in Iran. METHODS:The Survey of Risk Factors of Noncommunicable Diseases was conducted in 2005 and contains a representative sample of the Iranian adult populat...

journal_title：American journal of hypertension

authors： Esteghamati A,Abbasi M,Alikhani S,Gouya MM,Delavari A,Shishehbor MH,Forouzanfar M,Hodjatzadeh A,Ramezani RD

更新日期：2008-06-01 00:00:00

abstract：:To evaluate the possible physiologic role of atrial natriuretic factor (ANF) in the observed dissociation of aldosterone secretion from the renin-angiotensin system during hypoxic exercise, 12 untrained men, ages 18 to 24, were studied on two separate days for 30 min during hypoxic (16% O2) and normoxic (room air) exe...

journal_title：American journal of hypertension

authors： Lawrence DL,Shenker Y

更新日期：1991-04-01 00:00:00