Recent advances in management of gastroesophageal reflux.

Abstract:

:Gastroesophageal reflux is not synonymous with sliding hiatus hernia. It should be approached as a condition dependent on the intrinsic strength of the lower esophageal sphincter rather than on the presence of a hiatus hernia. The patient's account of symptoms is probably the most important means of diagnosis, but in addition the patient's history should be supplemented by radiographic evaluation. Initially the treatment of gastroesophageal reflux is one of prevention. If this conservative approach proves ineffective, drugs that restore sphincter strength can be tried. Surgery should be resorted to only if medical treatment fails, and then one of the newer specific antireflux procedures should be the operation of choice.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Cohen S

doi

10.1080/00325481.1975.11713946

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

97-102

issue

1

eissn

0032-5481

issn

1941-9260

journal_volume

57

pub_type

杂志文章
  • Counseling the parents of birth-defective children.

    abstract::Parents of a child who is diagnosed as defective face a crisis for which they are usually unprepared. They need an opportunity to work through their intense feelings. In addition, they need specific information about how to be of use to their child. Self-help groups composed of parents of children with a similar handi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1979.11715093

    authors: Vernon M

    更新日期:1979-03-01 00:00:00

  • Taking aim at HDL-C. Raising levels to reduce cardiovascular risk.

    abstract::Although statin therapy has revolutionized management of coronary heart disease (CHD), the lowering of low-density lipoprotein cholesterol (LDL-C) levels is not the whole story. Increased plasma concentrations of high-density lipoprotein cholesterol (HDL-C) have a cardioprotective effect that is just as important for ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2005.04.1610

    authors: McGovern ME

    更新日期:2005-04-01 00:00:00

  • Nonmelanoma skin cancer. Risks, treatment options, and tips on prevention.

    abstract::The incidence of nonmelanoma skin cancer is rapidly increasing. With early diagnosis and treatment, almost all basal cell and squamous cell carcinomas can be cured. Premalignant actinic keratoses are treated with cryosurgery; the CO2 laser is the treatment of choice for actinic cheilitis. Generally, nonmelanoma skin c...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:

    authors: Kibarian MA,Hruza GJ

    更新日期:1995-12-01 00:00:00

  • Efficacy and safety of ranolazine in patients with chronic stable angina.

    abstract::Chronic stable angina (CSA) impairs patient quality of life, is associated with increased patient mortality, and is a prominent symptom of coronary artery disease (CAD), the latter being prevalent worldwide in patients. Currently, therapeutic options for patients with CSA include β-blockers, calcium channel blockers, ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2013.11.2711

    authors: Kloner RA,Hines ME,Geunes-Boyer S

    更新日期:2013-11-01 00:00:00

  • The new hepatitis B vaccine. How, when, and why to use it.

    abstract::A hepatitis B vaccine derived from the plasma of carriers of hepatitis B virus has recently become generally available in the United States. Its use is recommended in groups considered to be at high risk of hepatitis B because of their exposure to potentially infectious blood, saliva, or semen. Experience in more than...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11697828

    authors: Kutcher WL

    更新日期:1983-05-01 00:00:00

  • Chemosensory dysfunction. Clinical evaluation results from a taste and smell clinic.

    abstract::Findings from 441 patient evaluations performed at the Taste and Smell Clinic of the Connecticut Chemosensory Clinical Research Center are presented. Taste and smell dysfunction was the chief complaint in all patients. The diagnostic approach included tests of taste and smell function; history taking; physical, neurol...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699680

    authors: Goodspeed RB,Gent JF,Catalanotto FA

    更新日期:1987-01-01 00:00:00

  • Advances in interventional radiology. The search for less invasive management sparks new approaches.

    abstract::Many new, minimally invasive interventional radiology procedures are now viable alternatives to traditional invasive therapy. The radiology procedures can often be performed in the outpatient setting, and although expensive technology may be required, the overall cost to the patient may be lower in the long run. Endov...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2001.06.958

    authors: Montgomery ML,Sullivan JP

    更新日期:2001-06-01 00:00:00

  • Cushing's syndrome. How to pinpoint and treat the underlying cause.

    abstract::In addition to prolonged glucocorticoid therapy (not discussed here), at least five other conditions cause Cushing's syndrome. They are excessive corticotropin secretion by the pituitary gland (which results in Cushing's disease), ectopic production of corticotropin by malignant nonpituitary tumors, benign adrenal ade...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1989.11704497

    authors: Felicetta JV

    更新日期:1989-12-01 00:00:00

  • Managing the patient with Parkinson's disease.

    abstract::When patients have a clear understanding of the etiology and pathophysiology of Parkinson's disease, management is easier for the physician and the patient is better able to cope with the disease. Patients also should be made aware of the proper use of antihistamines and anticholinergics that control tremor, as well a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1980.11715531

    authors: Riley TL,Massey EW

    更新日期:1980-09-01 00:00:00

  • Anemia of chronic disease.

    abstract::Anemia is one of the consistent findings with inflammation. Whether the anemia is helpful or harmful in the general context of the illness is unclear. It may be recognized by demonstration of iron-deficient erythropoiesis due to an internal block in iron supply. Only when its severity is disproportionate to the severi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1978.11714951

    authors: Finch CA

    更新日期:1978-10-01 00:00:00

  • The implications of tamper-resistant formulations for opioid rotation.

    abstract::Because rates of both opioid prescribing and opioid abuse have increased, drug companies have responded by considering strategies to make opioid formulations less attractive for abuse without compromising safety or efficacy for patients with legitimate pain management needs. The emergence of tamper-resistant opioid fo...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2012.09.2588

    authors: Pappagallo M,Sokolowska M

    更新日期:2012-09-01 00:00:00

  • Layered closure of lacerations.

    abstract::The cause, depth, and location of a laceration are major determining factors in its treatment. In all cases, the wound must be completely cleansed with irrigation under pressure and then examined radiographically if necessary and debrided. Successful repair depends on understanding and using the principles of wound he...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1988.11700310

    authors: Phillips LG,Heggers JP

    更新日期:1988-06-01 00:00:00

  • Beneficial effects resulting from thiazolidinediones for treatment of type 2 diabetes mellitus.

    abstract::Because new drugs continue to be developed, physicians treating patients with type 2 diabetes have a wide range of agents from which to choose. The newest class, the thiazolidinediones (TZDs), should be a mainstay of treatment for most patients with type 2 diabetes, because these agents reduce insulin resistance as we...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Bell DS

    更新日期:2003-05-01 00:00:00

  • Coughing up a stone. What to do about broncholithiasis.

    abstract::Broncholithiasis, a disease that is probably much more common than has been reported, is most often associated with pulmonary infections, for example, tuberculosis and histoplasmosis. Stones originate from calcified peribronchial lymph nodes that erode into the tracheobronchial tree, but lithoptysis occurs infrequentl...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1988.11700166

    authors: Haines JD Jr

    更新日期:1988-02-15 00:00:00

  • Cutaneous irritancy of an ibuprofen medicated plaster in healthy volunteers.

    abstract:OBJECTIVE:Ibuprofen is a commonly used non-steroidal anti-inflammatory drug administered to treat injuries, joint pain, and recurrent muscular skeletal pain. The aim of this study was to determine the cutaneous irritancy of a medicated ibuprofen plaster compared with a placebo plaster in healthy volunteers. METHODS:He...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00325481.2018.1398047

    authors: Maganji M,Connolly MP,Bhatt A

    更新日期:2018-01-01 00:00:00

  • Rheumatoid arthritis. Targeted interventions can minimize joint destruction.

    abstract::Rheumatoid arthritis can cause joint erosion and deformity, pain, stiffness, and decreased function and range of motion. Early diagnosis is crucial to prevent permanent joint damage. In this article, Drs Williams and Fye discuss articular and extra-articular manifestations of rheumatoid arthritis as well as the evolvi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2003.11.1525

    authors: Williams EA,Fye KH

    更新日期:2003-11-01 00:00:00

  • Uncomplicated peptic ulcer disease. An overview of formation and treatment principles.

    abstract::The end point in peptic ulcer disease is a crater in the mucosa. The cause of gastric ulcers seems to be the breakdown of defensive factors, which then allows damage from endogenous and/or exogenous aggressive factors. Aggressive factors are more important in duodenal ulcer formation. Treatment options discussed herei...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11701642

    authors: Ziller SA 3rd,Netchvolodoff CV

    更新日期:1993-03-01 00:00:00

  • Treating a transgender patient: overview of the guidelines.

    abstract::Transgenderism and gender dysphoria are becoming more prevalent diagnoses and the patient population is increasing. Primary care practitioners, endocrinologists, and mental health professionals are all part of the medical care team that treats these patients, but family and internal medicine physicians continue to del...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2014.11.2840

    authors: Wilczynski C,Emanuele MA

    更新日期:2014-11-01 00:00:00

  • Psychiatry: unresolved grief. Clinical considerations.

    abstract::Unresolved grief refers either to the absence or to the prolongation of normal grief. It is identified by (1) painful response to recall of the deceased, (2) realization of not having accepted the loss or of not being able to grieve, and (3) unaccountable depression, emergence of medical symptoms on the anniversary of...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11714374

    authors: DeVaul RA,Zisook S

    更新日期:1976-05-01 00:00:00

  • Dermatologic emergencies.

    abstract::Preview Several dermatoses are potentially fatal, and the mortality rate for some is quite high; prompt recognition and treatment are essential. Dr Gannon's succinct discussions of pemphigus vulgaris, necrotizing fasciitis, toxic epidermal necrolysis, Stevens-Johnson syndrome, toxic shock syndrome, and urticaria and a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1994.11945875

    authors: Gannon T

    更新日期:1994-07-01 00:00:00

  • Office gynecology: fibroids-when not to operate.

    abstract::The mere presence of uterine fibroids is not, since qua non, an indication for their surgical removal. Knowing when not to operate is probably more important for the physician than knowing when to operate. It is easy to fall into diagnostic and therapeutic traps when uterine fibroids are known to be present, especiall...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:

    authors: Russell KP

    更新日期:1976-09-01 00:00:00

  • Hypercalcemia.

    abstract::Preview An elevated serum calcium level requires thorough investigation. Is hyperparathyroidism at the root of the abnormality? Malignant disease? Vitamin toxicity? In this article, Dr Kaye discusses clinical evaluation of hypercalcemia and outlines pharmacologic therapy, surgical intervention, and other treatment opt...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1995.11945953

    authors: Kaye TB

    更新日期:1995-01-01 00:00:00

  • Behavioral medicine. Broadening the interface between medicine and behavioral science.

    abstract::The work of psychotherapists who have a cognitive-behavioral orientation and are trained in time-limited, focused psychotherapy has proved to be beneficial in the setting of a comprehensive medical and health maintenance organization. Group interventions that deal with relaxation, social skills, depression, agoraphobi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1984.11698601

    authors: Upper D,Kantor LE,Kulich RJ,Wurzelmann H,Bigwood GF

    更新日期:1984-02-15 00:00:00

  • Medical clearance for vigorous exercise. Clinical evaluation and exercise testing.

    abstract::The practitioner plays an important role in providing guidance for exercise. Physical activity is one component of a life-style aimed at enhancing the health of the individual. When entered into with appropriate understanding and with reasonable expectations and goals, exercise can also be a major source of enjoyment....

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1988.11700108

    authors: Smith LK

    更新日期:1988-01-01 00:00:00

  • Treating serum lipid abnormalities in high-priority patients.

    abstract::Normalization of serum lipid levels should be initiated as soon as possible in patients with myocardial, cerebrovascular, or peripheral vascular disease. Clinical trials indicate that coronary artery disease and overall mortality rates can be reduced and atherosclerosis stabilized or reversed by lipid-lowering therapy...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1991.11700787

    authors: Blankenhorn DH,Hodis HN

    更新日期:1991-01-01 00:00:00

  • patient notes index.

    abstract::Patient Notes are indexed alphabetically and by subject. The number immediately following the title is the number of the Patient Note, and the number in parentheses is the date of publication. This index includes all 82 Patient Notes published so far, from February 1, 1988, through this issue. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1993.11701589

    authors:

    更新日期:1993-01-01 00:00:00

  • Resource use and costs in high-risk symptomatic peripheral artery disease patients with diabetes and prior acute coronary syndrome: a retrospective analysis.

    abstract:OBJECTIVES:As the prevalence of peripheral artery disease (PAD) increases there is growing concern about the associated healthcare burden. This burden has not been well-characterized in high-risk patients with concurrent diabetes and/or acute coronary syndrome (ACS). The objective of this analysis was to assess comorbi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2016.1144447

    authors: Reed Chase M,Friedman HS,Navaratnam P,Heithoff K,Simpson RJ Jr

    更新日期:2016-01-01 00:00:00

  • Asthma and COPD: definitions, epidemiology, and treatment guidelines.

    abstract::Asthma and chronic obstructive pulmonary disease (COPD) are disorders that affect millions of people in the United States and other countries in the world. Asthma is a chronic inflammatory disease of the airways that has cellular and molecular pathways. Affected patients have recurrent episodes of wheezing, dyspnea, c...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.12.2005.suppl44.232

    authors: Berger WE,Cline DC

    更新日期:2005-12-01 00:00:00

  • Neonatal jaundice: when to treat, when to watch and wait.

    abstract::What clinical circumstances call for aggressive treatment of jaundice in newborns? Is cessation of breast-feeding necessary to help bring down the high bilirubin concentration? When should phototherapy be started--and stopped? The authors address these and other questions in this thorough guide to differential diagnos...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Lasker MR,Holzman IR

    更新日期:1996-03-01 00:00:00

  • Drug-induced illness. Causes for delayed diagnosis and a strategy for early recognition.

    abstract::Drug-induced illness is common in any clinical practice. The consequences of failure or delay in diagnosis--persistent or recurring illness, unnecessary diagnostic evaluation, inappropriate treatment, and future jeopardy from the drug--can be avoided by early recognition. Using descriptions of cases from his practice,...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1980.11715344

    authors: Savett LA

    更新日期:1980-01-01 00:00:00