A single cell analysis of apoptosis. Ordering the apoptotic phenotype.

abstract：:Like other somatic cells, human T lymphocytes have a finite replicative capacity in vitro, and, by implication and consistent with the limited data available, in vivo as well. An accumulation of dysfunctional T cells may be detrimental under conditions of chronic antigenic stress (chronic infection, cancer, autoimmuni...

journal_title：Annals of the New York Academy of Sciences

authors： Pawelec G,Mariani E,McLeod J,Ben-Yehuda A,Fulop T,Aringer M,Barnett Y

更新日期：2004-06-01 00:00:00

abstract：:This work examines distinct aspects of effortful control and attention predicted aggression in a group of children at elevated risk for the development of conduct problems. Results suggested that behavioral inhibition, rather than attentional control, best predicted maternal reports of child aggressive behaviors. ...

journal_title：Annals of the New York Academy of Sciences

authors： Dennis TA,Brotman LM

更新日期：2003-12-01 00:00:00

abstract：:Systemic administration of 5,7-HT to newborn rats produces an altered development of the 5-HT neurons in the central nervous system, with marked regional differences. 5,7-Hydroxytryptamine can enter the brain and elicit its neurotoxic actions after systemic administration in the neonatal stage due to an incompletely d...

journal_title：Annals of the New York Academy of Sciences

authors： Jonsson G,Pollare T,Hallman H,Sachs C

更新日期：1978-06-12 00:00:00

abstract：:Ischemia and reperfusion injure the heart, as manifested by myocardial infarction, postischemic ventricular functional dysfunctions, arrhythmias, and cardiomyocyte apoptosis. Hearts can be adapted to ischemic-reperfusion injury by subjecting them to non-lethal cyclic episodes of short-term ischemia and reperfusion. Th...

journal_title：Annals of the New York Academy of Sciences

authors： Maulik N,Sasaki H,Galang N

更新日期：1999-06-30 00:00:00

abstract：:Phosphorus nuclear magnetic resonance studies of various normal and dystrophic muscles have demonstrated differences in phosphodiester contents. Dystrophic chicken pectoralis muscle contains elevated levels of the diester SEP, and Duchenne dystrophic human leg muscle lacks the diester GPC. It is shown that SEP may be ...

journal_title：Annals of the New York Academy of Sciences

authors： Chalovich JM,Burt CT,Danon MJ,Glonek T,Bárány M

更新日期：1979-01-01 00:00:00

abstract：:Clostridium difficile infection, also known as C. difficile-associated diarrhea (CDAD), is the most common cause of nosocomial diarrhea, typically initiated by the use of broad-spectrum antibiotics that disrupt gut flora, thereby allowing C. difficile to proliferate. It is an increasing cause of morbidity and mortalit...

journal_title：Annals of the New York Academy of Sciences

authors： Sears P,Ichikawa Y,Ruiz N,Gorbach S

更新日期：2013-07-01 00:00:00

abstract：:In the popular and widely used Atkins diet, the body burns fat as its main fuel. This process produces ketosis and hence increased levels of beta-hydroxybutyrate (BOB) acetoacetate (AcAc) and its by-products acetone and acetol. These products are potential precursors of the glycotoxin methylglyoxal. Since methylglyoxa...

journal_title：Annals of the New York Academy of Sciences

authors： Beisswenger BG,Delucia EM,Lapoint N,Sanford RJ,Beisswenger PJ

更新日期：2005-06-01 00:00:00

abstract：:Mutualistic interactions, where two interacting species have a net beneficial effect on each other's fitness, play a crucial role in the survival and evolution of many species. Despite substantial empirical and theoretical work in past decades, the impact of these interactions on natural selection is not fully underst...

journal_title：Annals of the New York Academy of Sciences

authors： Hillesland KL

更新日期：2018-06-01 00:00:00

abstract：:HIV encephalopathy has been in the past years the most typical CNS disorder in patients with AIDS. Histologic abnormalities consist in astrocytosis, myelin pallor, infiltration by infected macrophages, resident microglia and multinucleated giant cells, generally in absence of direct infection of neurons. Mononuclear p...

journal_title：Annals of the New York Academy of Sciences

authors： Antinori A,Giancola ML,Alba L,Soldani F,Grisetti S

更新日期：2001-11-01 00:00:00

abstract：:Recent immunologic studies have provided important new information about the nature of AHF deficiency diseases and the structure and synthesis of this protein. They provide, moreover, a considerably improved ability to identify the carrier state in hemophilia A. Additional progress may be possible in the identificatio...

journal_title：Annals of the New York Academy of Sciences

authors： Hoyer LW,Rick ME

更新日期：1975-01-20 00:00:00

abstract：:Bacterial protein, staphylocoagulase, binds stoichiometrically to human prothrombin resulting in a coagulant complex, staphylothrombin. The enzymatic properties of staphylothrombin differ from those of alpha-thrombin in their substrate specificities toward natural and synthetic substrates, in addition to their interac...

journal_title：Annals of the New York Academy of Sciences

authors： Kawabata S,Morita T,Miyata T,Kaida S,Igarashi H,Iwanaga S

更新日期：1986-01-01 00:00:00

abstract：:As recently as ten years ago, the nature of the T-cell receptor for antigen was a mystery, as was the precise role of histocompatibility molecules in antigen-presentation to T cells. Although T-cell receptors have now been cloned and crystal structures of MHC/peptide molecules exist, our understanding of the parameter...

journal_title：Annals of the New York Academy of Sciences

authors： Boniface JJ,Davis MM

更新日期：1995-09-07 00:00:00

abstract：:B lymphocytes contribute to the pathogenesis of autoimmune disorders since B-cell depletion treatment improves such diseases. However, B cells seem ambivalent. Murine strains of nonorgan-specific as well as organ-specific autoimmune conditions present with aggravated symptoms when B cells are depleted. It is thus like...

journal_title：Annals of the New York Academy of Sciences

authors： Lemoine S,Morva A,Youinou P,Jamin C

更新日期：2009-09-01 00:00:00

abstract：:The availability of computer-controlled artificial hearts, kidneys, and lungs, as well as the possibility of implanting human embryos in ex vivo uterus models or an artificial endometrium, presents new perspectives for creating an artificial uterus. Survival rates have also improved, with fetuses surviving from as ear...

journal_title：Annals of the New York Academy of Sciences

authors： Bulletti C,Palagiano A,Pace C,Cerni A,Borini A,de Ziegler D

更新日期：2011-03-01 00:00:00

abstract：:In most countries, tuberculosis caused by Mycobacterium bovis is mainly a disease of domestic cattle and can be controlled successfully by means of a test-and-slaughter program. Once the infection spills over into a wild animal species with maintenance host potential, conventional measures are no longer sufficient to ...

journal_title：Annals of the New York Academy of Sciences

authors： Michel AL

更新日期：2002-10-01 00:00:00

abstract：:Eight children with congenital adrenal hyperplasia and late initiation of corticosteroid treatment are included in the present study. Four of them received LHRHa treatment for the arrest of central precocious puberty, while the other four served as controls. The administration of LHRHa was effective in arresting the m...

journal_title：Annals of the New York Academy of Sciences

authors： Dacou-Voutetakis C,Karidis N

更新日期：1993-05-28 00:00:00

abstract：:During relapses in relapsing-remitting multiple sclerosis (RRMS), serum soluble HLA class I surface antigen (sHLA-I) levels are reported to either decrease or remain unchanged, whereas serum sHLA-II levels increase. Interferon-beta1b therapy was recently reported to increase serum sHLA-I in RRMS. In the present prospe...

journal_title：Annals of the New York Academy of Sciences

authors： Minagar A,Adamashvilli I,Jaffe SL,Glabus MF,Gonzalez-Toledo E,Kelley RE

更新日期：2005-06-01 00:00:00

abstract：:Converging lines of evidence indicate that withdrawal from prolonged exposure to stimulants and alcohol results in synaptic deficits of both dopamine (DA) and serotonin (5-HT). According to the dual deficit model proposed by the authors, DA dysfunction during cocaine or alcohol withdrawal underlies anhedonia and psych...

journal_title：Annals of the New York Academy of Sciences

authors： Rothman RB,Partilla JS,Dersch CM,Carroll FI,Rice KC,Baumann MH

更新日期：2000-09-01 00:00:00

abstract：:We have evaluated the performance of a novel line-blot immunoassay (LIA; Mikrogen) and compared results with those obtained by CIE (in-house), ELISA (Pharmacia Diagnostics), and FEIA (Pharmacia Diagnostics). Sera from systemic lupus erythematosus (SLE) patients (n = 123), systemic sclerosis patients (n = 25), and heal...

journal_title：Annals of the New York Academy of Sciences

authors： Damoiseaux J,Boesten K,Giesen J,Austen J,Tervaert JW

更新日期：2005-06-01 00:00:00

abstract：:Using a newly developed algorithm in conjunction with the front tracking scheme, we have evaluated the transport associated with a deformable bubble moving in a tube in the presence of a soluble or an insoluble surfactant. Such evaluations are useful to the understanding of gas embolism--a common syndrome for decompre...

journal_title：Annals of the New York Academy of Sciences

authors： Ayyaswamy PS,Zhang J,Eckmann DM

更新日期：2006-09-01 00:00:00

abstract：:Human diploid fibroblasts (WI38) were inoculated into Rose multipurpose culture chambers, using a high population density to develop confluency. After 24 hours, cells from a 1 mm swath were scraped from the center of the chamber. This cleared path was positioned to permit an unobstructed transmission of a 0.9 X 20 mm ...

journal_title：Annals of the New York Academy of Sciences

authors： Rounds DE,Olson RS,Booher J

更新日期：1976-01-30 00:00:00

abstract：:Taking into account that methamphetamine (MA) is a popular recreational drug among young adult women, i.e., in gestational age, the present model aims to assess the effects of its exposure during development. In this experimental model, MA effects are assessed in the rat during the first month of life, regarding both ...

journal_title：Annals of the New York Academy of Sciences

authors： Gomes-DA-Silva J,Silva MC,Tavares MA

更新日期：1998-05-01 00:00:00

abstract：:Astronomers and physicists of diverse interest are teaming up to study enigmatic cosmic phenomena, such as the life cycle of black holes. A "disruptive innovation" is about to emerge during the next decade: Advanced gravitational-wave observatories. The emergence of gravitational-wave physics as a viable observational...

journal_title：Annals of the New York Academy of Sciences

authors： Márka S

更新日期：2012-07-01 00:00:00

abstract：:The epidemiologic features are described of cases of human monocytic ehrlichiosis and human granulocytic anaplasmosis in the United States. ...

journal_title：Annals of the New York Academy of Sciences

authors： Demma LJ,Holman RC,McQuiston JH,Krebs JW,Swerdlow DL

更新日期：2006-10-01 00:00:00

abstract：:The kinetics of the E(2) --> E(1) conformational change of unphosphorylated Na(+),K(+)-ATPase from rabbit kidney were investigated via the stopped-flow technique using the fluorescent label RH421 (pH 7.4, 24 degrees C). The enzyme was preequilibrated in a solution containing 25 mM histidine and 0.1 mM EDTA to initiall...

journal_title：Annals of the New York Academy of Sciences

authors： Clarke RJ,Humphrey PA,Lüpfert C,Apell HJ,Cornelius F

更新日期：2003-04-01 00:00:00

abstract：:Aged F344 female rats (21 months) showed decreased performance, as compared to young rats (4 months), on an object recognition memory task. Golgi impregnation measured dendritic spine density of pyramidal neurons in the prefrontal cortex (layer II-III), a brain area important for recognition memory. Densities of spine...

journal_title：Annals of the New York Academy of Sciences

authors： Wallace M,Frankfurt M,Arellanos A,Inagaki T,Luine V

更新日期：2007-02-01 00:00:00

abstract：:The risk of cardiovascular (CV) disease increases in patients with rheumatoid arthritis (RA). This is due to a number of different triggers including traditional and disease-related factors. Among established risk factors for CV disease, smoking may exert a more dangerous effect on arterial wall in RA than in the gene...

journal_title：Annals of the New York Academy of Sciences

authors： Gerli R,Sherer Y,Bocci EB,Vaudo G,Moscatelli S,Shoenfeld Y

更新日期：2007-06-01 00:00:00

abstract：:Imatinib is a selective tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive leukemias and other malignancies. An important clinical observation is that imatinib can affect the function of normal nonmalignant cells resulting in myelosuppression in treated patients. This observation is s...

journal_title：Annals of the New York Academy of Sciences

authors： Balabanov S,Appel S,Kanz L,Brossart P,Brümmendorf TH

更新日期：2005-06-01 00:00:00

abstract：:Sex differences in social behavior are center stage in recent formulations of evolutionary psychology. Evolutionary psychology, with its emphasis on the long-term consequences of early adaptations, offers itself as an alternative meta-theory to mainstream social psychology, which emphasizes the importance of social st...

journal_title：Annals of the New York Academy of Sciences

authors： Rabinowitz VC,Valian V

更新日期：2000-04-01 00:00:00

abstract：:A mouse strain lacking SMP30 can be regarded as a strain showing ultimate decrease of the SMP30 molecule. After three months of age, SMP30-KO mice had an increased mortality rate, compared with the SMP30-WT mice, all of which remained alive. Electron microscopic observation of the hepatocytes from 12-month-old SMP30-K...

journal_title：Annals of the New York Academy of Sciences

authors： Maruyama N,Ishigami A,Kuramoto M,Handa S,Kubo S,Imasawa T,Seyama K,Shimosawa T,Kasahara Y

更新日期：2004-06-01 00:00:00