Abstract:
:There is a potential need for the official criterion of testosterone abuse in sport (the urinary concentration ratio of testosterone glucuronide/epitestosterone glucuronide, TG/EG > 6) to be backed-up by some complementary markers, more particularly in cases of physiologically high TG/EG and when there is suspicion of joint administration of testosterone and epitestosterone. Testosterone, epitestosterone, their glucuro- and sulfoconjugates, 5-androstene-3 beta, 17 alpha-diol glucuronide and 17-hydroxyprogesterone have been analysed by isotope dilution-gas chromatography-mass spectrometry in plasma and urine of seven subjects supplemented with a single oral dose of undecanoates of testosterone and epitestosterone (respectively 40 mg and 1.5 mg). Adequate plasma criteria for testosterone abuse were the ratios of testosterone glucuronide/17-hydroxyprogesterone and testosterone glucuronide/testosterone which increased significantly above basal values for up to 10 h. The same trend was observed for the ratio of urinary glucuronides of testosterone/5-androstene-3 beta, 17 alpha-diol, while TG/EG was not affected by simultaneous administration of epitestosterone. One subject with low basal TG/EG failed to respond to testosterone administration by any significant increase of analysed parameters.
journal_name
Int J Sports Medjournal_title
International journal of sports medicineauthors
Dehennin L,Pérès Gdoi
10.1055/s-2007-972853subject
Has Abstractpub_date
1996-07-01 00:00:00pages
315-9issue
5eissn
0172-4622issn
1439-3964journal_volume
17pub_type
杂志文章abstract::The nutrition of 57 native Bolivian boys living at high altitude (HA) in La Paz (+/- 4000 m) and of 63 boys living at low altitude (LA) in St. Cruz (+/- 400 m) is described. The dietary information was obtained with a 24-h recall method, by interviewing the child and mother. The food items are listed in household meas...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-1021121
更新日期:1994-04-01 00:00:00
abstract::Serum zinc was determined using atomic absorption spectrophotometry in 160 training athletes (57 females) in the morning at rest. In 23.3% of the male and 43% of the female athletes, serum Zn was lower than the limit accepted for the normal range (75 microgram/dl or 11.5 mumol/l). The average serum Zn (96.7 +/- 12.6 m...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2008-1034599
更新日期:1981-08-01 00:00:00
abstract::We have studied the effect of exercise on the percentage of free plasma estradiol 17-beta (E2) and testosterone (T) in 13 untrained (UT) and 8 trained (marathon runners, MR) eumenorrheic women. All women performed a standardized bicycle ergometer (UT) or treadmill (MR) test in the follicular and luteal phases of their...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2008-1025721
更新日期:1987-12-01 00:00:00
abstract::The hypothalamic-pituitary-testicular (H-P-T) axis was evaluated in groups of endurance-trained (TRG) and untrained (UNT) males. Each group was subjected to: 1) a 4-h resting hormonal profile [testosterone (T), free-testosterone (FT), estradiol (E2), luteinizing hormone (LH), prolactin (PRL), and cortisol (C)], 2) a d...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-1024811
更新日期:1990-08-01 00:00:00
abstract::Mechanical efficiency of positive work (eta+) and elastic behavior of human skeletal muscles were investigated on a special sledge apparatus which allowed the use of the normal stretch-shortening cycle exercises. Twenty-five young men were investigated in a total of 92 exercise situations, in which the intensity of th...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2008-1025751
更新日期:1986-06-01 00:00:00
abstract::Physical exercise is associated with increases of serum and salivary levels of cortisol. The concomitant increase in serum lactate has been implicated as one of the mechanisms responsible for adrenocortical activation. We evaluated the responses of serum lactate and serum and salivary cortisol to an acute bout of high...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2004-830449
更新日期:2005-11-01 00:00:00
abstract::The lipolytic and the cardiac responses to 30 min of two different forms of stress--a standardized mental stress test and submaximal bicycle exercise--were investigated in non-obese healthy subjects. This was done by microdialysis of the extracellular space in the abdominal subcutaneous adipose tissue in order to dete...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-1021079
更新日期:1994-10-01 00:00:00
abstract::To study the hypothesis that more severe damage, caused by controlled lengthening (L) contractions, results in greater myofiber hypertrophy compared to increase in fiber size followed shortening (S) contractions, tibialis anterior muscles of anesthesized male Wistar rats were subjected to 240 either L or S contraction...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2000-8869
更新日期:2000-02-01 00:00:00
abstract::One hundred and three women who were habitual distance runners and 74 age-matched physically inactive women provided three-day diet records. Intergroup differences in intakes of energy nutrients, micronutrients, cholesterol and fiber were evaluated via analysis of variance and, to assess qualitative differences, via a...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-1024838
更新日期:1990-12-01 00:00:00
abstract::The purpose of this study was to determine whether a player's physical impairment or activity profile was related to the amount of thermal strain experienced during wheelchair rugby match play. 17 elite wheelchair rugby players played a competitive match, whilst activity profiles, measures of core and skin temperature...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-0042-121263
更新日期:2017-03-01 00:00:00
abstract::Cardiac vagal tone (CVT), a key determinant of resting heart rate (HR), is progressively withdrawn with incremental exercise and nearly abolished at maximal effort. While maximal HR decreases with age, there remains a large interindividual variability of results for any given age. In the present study, we hypothesized...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-0032-1323818
更新日期:2013-06-01 00:00:00
abstract::The purpose of this study was to establish the validity of a 90-s all-out test for the estimation of maximal oxygen uptake (V.O (2max)) and submaximal aerobic ability as represented by critical power. We hypothesized that the fall in power output by the end of the 90-s all-out test (end power) would represent the exha...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2006-924513
更新日期:2007-05-01 00:00:00
abstract::The purpose of this study was to investigate the effects of recombinant human erythropoietin (rHuEPO) administration on energy metabolism during exercise. Specifically, the contribution of anaerobic (glycogen) metabolism during exercise was evaluated. Sprague-Dawley rats were randomly assigned to an experimental [rHuE...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-971919
更新日期:1998-05-01 00:00:00
abstract::The aim of the present study was to monitor the nutritional status of 9 Greek national top-level swimmers during a competitive season of eight months. The swimmers were assessed through recording of food and supplement intake, blood sampling, and anthropometry at four landmarks: in the beginning of the season (baselin...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-964907
更新日期:2007-09-01 00:00:00
abstract::Exercise induced pain in the posterior part of the leg is common among runners; the underlying reason for these complaints may be very different. The purpose of the present, controlled study was therefore 1. to confirm a clinically diagnosed deep posterior compartment syndrome by using intramuscular pressure measureme...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-972650
更新日期:1997-07-01 00:00:00
abstract::The present series of experiments were conducted to access the surface EMG frequency parameters during repeated fingertip isometric contractions to determine if they can be used as a fatigue index under specific grip used in rock climbing. Electromyograms of the finger flexors and extensors were characterised in ten e...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2003-41174
更新日期:2003-08-01 00:00:00
abstract::We compared 35 prepubertal girls, 9 artistic gymnasts and 13 rhythmic gymnasts with 13 nonphysically active controls to study the effect of gymnastics on bone and muscle mass. Lean mass, bone mineral content and areal density were measured by dual energy X-ray absorptiometry, and physical fitness was also assessed. Th...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2006-924397
更新日期:2007-05-01 00:00:00
abstract::The aim of the present study was to understand if sport improves attention symptoms, social competency, and cognitive functions in children with attention deficit and hyperactivity disorder (ADHD). The present study was designed as a 6-week, prospective trial, including 12 sessions of education/sports therapy. 13 ADHD...
journal_title:International journal of sports medicine
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0031-1283175
更新日期:2011-12-01 00:00:00
abstract::There are ethical objections to inducing cumulative muscle damage and associated decrements of performance deliberately in a healthy athlete. Available data on acute and chronic over-exertion thus include the changes of immune response observed following a single bout of exhausting exercise, sequential observations ma...
journal_title:International journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1055/s-2007-971898
更新日期:1998-04-01 00:00:00
abstract::Maximal voluntary contractions (MVC) were performed by five male subjects as repeated knee extensions separated by 13-s rest periods for the purposes of studying performance capability, physiologic responses, and recruitment patterns among fast-twitch (FT) and slow-twitch (ST) extrafusal muscle fibers for this type of...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2008-1034593
更新日期:1981-05-01 00:00:00
abstract::The oxygen uptake (VO2) attained during a constant speed 800-m pace trial on a treadmill is less than the maximal VO2 (VO2max) in male middle-distance runners with a high VO2max (i.e., > 65 ml x kg (-1) x min (-1)). We therefore investigated whether the VO2 attained was influenced by the pacing strategy adopted. Eight...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2005-837468
更新日期:2006-01-01 00:00:00
abstract::Training effects on peak oxygen consumption (VO2), specific to the mode of movement, are well-known in exercise training of young, healthy adults. However, these specific training effects were never studied in patients with coronary artery disease, but may be important in the evaluation of training effects of cardiac ...
journal_title:International journal of sports medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2007-971930
更新日期:1998-07-01 00:00:00
abstract::The ventilatory (anaerobic) threshold during short-term exercise has been defined as the O2 uptake (VO2) immediately below the VO2 at which pulmonary ventilation (VE) increases disproportionally relative to VO2 and the ventilatory threshold for long-term exercise as the VO2 immediately below the VO2 at which the VE co...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2008-1025730
更新日期:1986-02-01 00:00:00
abstract::Increasing exercise intensities will induce an increase in glycolytic flux. High glycolytic activity is associated with reduced fat oxidation rates and increased accumulation of lactate. Both lactate and hydrogen ions have been shown to be directly related to the decreased fat oxidation rates. The aim of the present s...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2003-45231
更新日期:2004-01-01 00:00:00
abstract::We aimed to determine whether blood flow restriction (BFR) alters the characteristics of individual motor units during low-intensity (LI) exercise. Eight men (26.0±3.8 yrs) performed 5 sets of 15 knee extensions at 20% of one-repetition maximum (with and without BFR). Maximal isometric voluntary contractions (MVC) wer...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/a-0888-8816
更新日期:2019-09-01 00:00:00
abstract::Three different procedures to analyse fencing performances were tested. The test subjects were ten world class epée fencers from the Swedish national team. The procedures involved measurements of reaction time and response time to different stimuli. Test 1 measured the lunging performance as a response to a light. Tes...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-1024736
更新日期:1991-12-01 00:00:00
abstract::In a group of male distance runners, 23 out of 45 athletes showed decreased serum ferritin values (< 35 micrograms). The high prevalence of a typical iron deficiency in runners was confirmed in a subgroup of eight athletes in which the iron metabolism was studied in detail using radio-iron labelling and liver iron qua...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-972881
更新日期:1996-10-01 00:00:00
abstract::Male Sprague-Dawley rats (n = 48, > 200 g) were progressively treadmill trained over 5 wk where they were running 60 min/d, 5 d/wk. One-half of the group consumed a high-fat diet (HF, 78.7% of energy), while one-half consumed a high-carbohydrate diet (HC, 68.7% of energy). On the day of the experiment, 6 rats per diet...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-971939
更新日期:1998-08-01 00:00:00
abstract::The purpose of this investigation was to determine the accuracy of the critical velocity (CV) test for predicting time to exhaustion (time limit = TL) during treadmill running. Ten adult males (mean +/- SD of age = 23 +/- 2 years) volunteered to perform a maximal treadmill test, a CV test, and five exhaustive treadmil...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-1021242
更新日期:1992-02-01 00:00:00
abstract::The effects of physical activity (PA) on bioenergetic characteristics were studied in 53 prepubertal boys. Maximal oxygen consumption (VO2max; direct method), maximal anaerobic power (Pmax, force-velocity test), and mean power in 30 s (P30s, Wingate test) were compared (mean +/- SD) in three groups of boys of the same...
journal_title:International journal of sports medicine
pub_type: 杂志文章
doi:10.1055/s-2007-1021208
更新日期:1993-11-01 00:00:00