Abstract：
:To study the hypothesis that more severe damage, caused by controlled lengthening (L) contractions, results in greater myofiber hypertrophy compared to increase in fiber size followed shortening (S) contractions, tibialis anterior muscles of anesthesized male Wistar rats were subjected to 240 either L or S contractions. The highest increase in muscle beta-glucuronidase activity, an indicator of muscle damage, was observed in L (7.1-fold) 4 days and in S (2.6-fold) 8 days postexercise. Dystrophin- and desmin-negative as well as fibronectin-positive fibers (signs of the early phase of damage) were observed immediately after exercise in the L group. At 4 days, massive myofiber injury was visible, and internally localized nuclei were present at 15-80 days after exercise in the L group. The shift towards more glycolytic fiber types (p<0.05 in L and S) and an increased mean cross-sectional area of type IIX/B fibers (p < 0.001 in L and S) at 80 days were observed in both groups. The observed minor damage with unchanged myofiber structures following S induced, however, an increase in myofiber cross-sectional area of nearly the same magnitude as that following L, which was more damaging. The results do not support the hypothesis that fiber hypertrophy depends on the extent of the myofiber damage upon the exercised muscles.
journal_name
Int J Sports Medjournal_title
International journal of sports medicineauthors
Komulainen J,Kalliokoski R,Koskinen SO,Drost MR,Kuipers H,Hesselink MKdoi
10.1055/s-2000-8869subject
Has Abstractpub_date
2000-02-01 00:00:00pages
107-12issue
2eissn
0172-4622issn
1439-3964journal_volume
21pub_type
杂志文章abstract：:Little information exists about the efficacy of various brace designs to restrict inversion during lateral movements. The purpose of the study was to determine whether semi-rigid stirrup (AirCast Sport Stirrup), semi-rigid modified stirrup (Malleoloc), or a soft, sleeve design (Swede-O) brace varied in their abilities...
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pub_type： 杂志文章
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journal_title：International journal of sports medicine
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journal_title：International journal of sports medicine
pub_type： 临床试验,杂志文章,随机对照试验
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