Abstract:
:Pesticide-induced oxidative stress as a possible mechanism of toxicity has been a focus of toxicological research for the last decade. Yet for certain pesticides, mechanisms leading to oxidative stress are only partly understood. Pesticide-induced oxidative stress is the final manifestation of a multi-step pathway, resulting in an imbalance between pro-oxidant and antioxidant defense mechanisms. Concomitantly, pesticide intoxication induces a derangement of certain antioxidant mechanisms in different tissues, including alterations in antioxidant enzymes and the glutathione redox system. In this article, we discuss the impact of certain factors that are important in the potentiation of pesticide-induced oxidative stress, immunotoxicity, and apoptosis. Understanding risk factors largely depends upon the cellular and molecular events underlying pesticide-induced stress in experimental animals. These factors must be considered in the safety/toxicity evaluation of any pesticide. The identification and characterization of plant products/drugs might be helpful for understanding the mechanisms of compensation and repair that are due to oxidative stress-induced injury. This paper reviews the nature of such damage, the cellular conditions in which it occurs, and oxidative-stress data that may be applied to the development of risk-assessment methods and models that are designed to reduce some of these uncertainties.
journal_name
Rev Environ Healthjournal_title
Reviews on environmental healthauthors
Banerjee BD,Seth V,Ahmed RSdoi
10.1515/reveh.2001.16.1.1subject
Has Abstractpub_date
2001-01-01 00:00:00pages
1-40issue
1eissn
0048-7554issn
2191-0308journal_volume
16pub_type
杂志文章,评审abstract::Environmental exposures are changing dramatically in location, intensity, and frequency. Many developing countries are undergoing a transition in which they face the double burden of infectious diseases as well as chronic diseases. Noncommunicable diseases have emerged as the leading cause of death and disability in d...
journal_title:Reviews on environmental health
pub_type: 杂志文章
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2013-0990
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journal_title:Reviews on environmental health
pub_type: 社论
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journal_title:Reviews on environmental health
pub_type: 杂志文章
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abstract::Background This review intends to explore the household hazardous waste (HHW) generation rates, HHW management, and people's awareness regarding HHW in Asian countries based on the economic levels using the available published articles. Methods This is a systematic review of the scientific literature based on several ...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2019-0049
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2012-0035
更新日期:2013-01-01 00:00:00
abstract::Cytostatic anticancer drugs are known as carcinogenic, mutagenic, and teratogenic risk factors for health care workers who are occupationally exposed during the preparation and administration of such drugs. During the last 20 years, several researchers have developed and validated methods to monitor occupational expos...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.1997.12.1.43
更新日期:1997-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2018-0057
更新日期:2019-03-26 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh.1994.10.1.67
更新日期:1994-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2016-0040
更新日期:2016-12-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2003.18.1.33
更新日期:2003-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0036
更新日期:2016-03-01 00:00:00
abstract::Protecting the public from waterborne diseases is an environmental health responsibility that every government worldwide must deal with. Canada's recent experience with waterborne outbreaks has brought the effectiveness of its water-monitoring and treatment systems under scrutiny. This paper focuses on microbial water...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2008.23.2.119
更新日期:2008-04-01 00:00:00
abstract::Children living in poverty are disproportionately at risk from and affected by environmental hazards. According to the National Center for Children in Poverty, 13 million children in America live in poverty. Thus, not only are millions of children living in poverty but are also living in environments that are hazardou...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2011.021
更新日期:2011-01-01 00:00:00
abstract::Nowadays the use of conventional wastewater treatment methods is becoming increasingly challenging mainly due to the presence of organic matter in wastewater. Therefore, an emerging technology is needed to deal with these highly concentrated and toxic non-biodegradable organic matters. In the last few decades, advance...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2019-0024
更新日期:2019-12-18 00:00:00
abstract::Aedes aegypti mosquitoes are primary vectors of dengue, yellow fever, chikungunya and Zika viruses. Ae. aegypti is highly anthropophilic and relies nearly exclusively on human blood meals and habitats for reproduction. Socioeconomic factors may be associated with the spread of Ae. aegypti due to their close relationsh...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2020-0028
更新日期:2020-08-24 00:00:00
abstract::The indoor environment is a major source of human exposure to pollutants. Some pollutants can have concentrations that are several times higher indoors than outdoors. Prolonged exposure may lead to adverse biologic effects, even at low concentrations. Several studies done in Malaysia had underlined the role of indoor ...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2014-0065
更新日期:2015-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2014-0016
更新日期:2014-01-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh.2009.24.2.147
更新日期:2009-04-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.1997.12.3.191
更新日期:1997-07-01 00:00:00
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journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-1989-1-407
更新日期:1989-01-01 00:00:00
abstract::Six organochlorine pesticides and pesticide metabolites in human blood were tested to determine their relationships with diabetic nephropathy. The data were derived from the National Health and Nutrition Examination Survey (NHANES) 1999-2004 (unweighted, n=2992, population estimate=133,088,752). The six chemicals were...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2015-0003
更新日期:2015-01-01 00:00:00
abstract::Polybrominated diphenyl ethers (PBDEs) are a class of synthetic halogenated organic compounds used in commercial and household products, such as textiles, furniture, and electronics, to increase their flame ignition resistance and to meet fire safety standards. The demonstrated persistence, bioaccumulation, and toxic ...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh.2009.24.3.157
更新日期:2009-07-01 00:00:00
abstract::Surveillance systems to inform controls for waterborne disease (WBD) are important for the protection of public health. Member States of the European Union (EU) will soon be required to implement Directives and the Protocol on Water and Health for controlling WBD. The investigation reported here considers the consiste...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh.2002.17.2.149
更新日期:2002-04-01 00:00:00
abstract::In our environment, various naturally occurring radionuclides are present (both underground and overground) in several places, which results in lifelong human exposure. The radiation dose received by human beings from the radiation emitted by these naturally occurring radionuclides is approximately 87%. Exposure to ra...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2018-0058
更新日期:2019-06-26 00:00:00
abstract::Vapor intrusion (VI) is a term used to describe indoor air (IA) contamination that occurs due to the migration of chemical vapors in the soil and groundwater. The overall vapor transport process depends on several factors such as contaminant source characteristics, subsurface conditions, building characteristics, and ...
journal_title:Reviews on environmental health
pub_type: 杂志文章,评审
doi:10.1515/reveh-2016-0039
更新日期:2017-03-01 00:00:00
abstract::AbstractThe National Institute of Environmental Health Sciences Superfund Research Program (SRP) funds diverse transdisciplinary research to understand how hazardous substances contribute to disease. SRP research focuses on how to prevent these exposures by promoting problem-based, solution-oriented research. SRP's ma...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2020-0073
更新日期:2020-08-31 00:00:00
abstract::Nanoscale titanium dioxide (nanoTiO2) is a commercially important nanomaterial used in numerous applications. Experimental studies with nanotitania have documented lung injury and inflammation, oxidative stress, and genotoxicity. Production workers in TiO2 manufacturing with a high proportion of nanoparticles and a mi...
journal_title:Reviews on environmental health
pub_type: 杂志文章
doi:10.1515/reveh-2016-0030
更新日期:2017-03-01 00:00:00